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    GOLGA3 golgin A3 [ Homo sapiens (human) ]

    Gene ID: 2802, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    An exome-first approach to aid in the diagnosis of primary ciliary dyskinesia.

    An exome-first approach to aid in the diagnosis of primary ciliary dyskinesia.
    Shamseldin HE, Al Mogarri I, Alqwaiee MM, Alharbi AS, Baqais K, AlSaadi M, AlAnzi T, Alhashem A, Saghier A, Ameen W, Ibrahim N, Yang J, Abdulwahab F, Hashem M, Chivukula RR, Alkuraya FS.

    09/26/2020
    Golgin-160 disperses from Golgi membranes in cells subjected to cold temperature. Activated ARF1 can prevent cold-induced dispersal of golgin-160.

    Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins.
    Gilbert CE, Sztul E, Machamer CE., Free PMC Article

    02/2/2019
    The golgin-160 binds directly to the third intracellular loop of beta1AR and that this binding depends on three basic residues in this loop.

    Three basic residues of intracellular loop 3 of the beta-1 adrenergic receptor are required for golgin-160-dependent trafficking.
    Gilbert CE, Zuckerman DM, Currier PL, Machamer CE., Free PMC Article

    04/4/2015
    Golgi protein golgin160 recruits dynein to Golgi membranes.

    Golgin160 recruits the dynein motor to position the Golgi apparatus.
    Yadav S, Puthenveedu MA, Linstedt AD., Free PMC Article

    10/13/2012
    A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic patient

    Identification of a common autoantigenic epitope of protein disulfide isomerase, golgin-160 and voltage-gated potassium channel in type 1 diabetes.
    Fierabracci A, Saura F.

    08/16/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    nuclear translocation of golgin-160-(140-311) is a highly coordinated event regulated not only by cleavage of the golgin-160 head but also by the oxidation state of GCP60

    Identification of a redox-sensitive cysteine in GCP60 that regulates its interaction with golgin-160.
    Sbodio JI, Machamer CE.

    01/21/2010
    results indicate that GCP16 is the acylated membrane protein, associated with GCP170, and possibly involved in vesicular transport from the Golgi to the cell surface

    Identification and characterization of GCP16, a novel acylated Golgi protein that interacts with GCP170.
    Ohta E, Misumi Y, Sohda M, Fujiwara T, Yano A, Ikehara Y.

    01/21/2010
    NH2 terminal domain of Golgin 160 has a role in nuclear transport and Golgi apparatus localization

    The NH2-terminal domain of Golgin-160 contains both Golgi and nuclear targeting information.
    Hicks SW, Machamer CE.

    01/21/2010
    golgin-160 may promote efficient surface delivery of a subset of cargo molecules

    Golgin-160 promotes cell surface expression of the beta-1 adrenergic receptor.
    Hicks SW, Horn TA, McCaffery JM, Zuckerman DM, Machamer CE.

    01/21/2010
    Caspase-resistant GOLGA3 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors.

    Caspase-resistant Golgin-160 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors.
    Maag RS, Mancini M, Rosen A, Machamer CE., Free PMC Article

    01/21/2010
    GCP60 interacts preferentially with one of the golgin-160 caspase cleavage fragments (residues 140-311). This strong interaction prevented the golgin-160 fragment from accumulating in the nucleus when this fragment and GCP60 were overexpressed.

    GCP60 preferentially interacts with a caspase-generated golgin-160 fragment.
    Sbodio JI, Hicks SW, Simon D, Machamer CE.

    01/21/2010
    golgin-160 assosiates in an isoform-specific manner with the Golgi-associated protein PIST

    Isoform-specific interaction of golgin-160 with the Golgi-associated protein PIST.
    Hicks SW, Machamer CE.

    01/21/2010
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