| Heat shock protein B7 (HSPB7) inhibits lung adenocarcinoma progression by inhibiting glycolysis. | Heat shock protein B7 (HSPB7) inhibits lung adenocarcinoma progression by inhibiting glycolysis.
Chen Z, Li P, Shen L, Jiang X., Free PMC Article | 09/26/2023 |
| HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis. | HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis.
Zhang S, van de Peppel J, Koedam M, van Leeuwen JPTM, van der Eerden BCJ., Free PMC Article | 05/18/2023 |
| Is the small heat shock protein HSPB7 (cvHsp) a genuine actin-binding protein? | Is the small heat shock protein HSPB7 (cvHsp) a genuine actin-binding protein?
Muranova LK, Shatov VM, Slushchev AV, Gusev NB. | 11/26/2022 |
| HSPB7 regulates osteogenic differentiation of human adipose derived stem cells via ERK signaling pathway. | HSPB7 regulates osteogenic differentiation of human adipose derived stem cells via ERK signaling pathway.
Jin C, Shuai T, Tang Z., Free PMC Article | 07/3/2021 |
| Cardio-Vascular Heat Shock Protein (cvHsp, HspB7), an Unusual Representative of Small Heat Shock Protein Family. | Cardio-Vascular Heat Shock Protein (cvHsp, HspB7), an Unusual Representative of Small Heat Shock Protein Family.
Muranova LK, Shatov VM, Bukach OV, Gusev NB. | 05/29/2021 |
| HSPB7 Gene Polymorphism Associated with Anthropometric Parameters of Obesity and Fat Intake in a Central European Population. | HSPB7 gene polymorphism associated with anthropometric parameters of obesity and fat intake in a Central European population.
Pavlová T, Novák J, Zlámal F, Bienertová-Vašků J. | 05/11/2019 |
| SRARP and HSPB7 are tumor suppressors that are commonly inactivated in malignancies. | SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies.
Naderi A., Free PMC Article | 03/30/2019 |
| Loss of Hspb7 in zebrafish or human cardiomyocytes stimulated autophagic pathways and expression of the sister gene encoding Hspb5. Inhibiting autophagy caused FilaminC aggregation in HSPB7 mutant human cardiomyocytes and developmental cardiomyopathy in hspb7 mutant zebrafish embryos. | Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis.
Mercer EJ, Lin YF, Cohen-Gould L, Evans T., Free PMC Article | 03/31/2018 |
| our findings characterize HSPB7 as an intercalated disc protein and suggest it has an essential role in maintaining intercalated disc integrity and conduction function in the adult heart. | HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity.
Liao WC, Juo LY, Shih YL, Chen YH, Yan YT., Free PMC Article | 09/16/2017 |
| Patients with central sleep apnea and congestive heart failure had higher T allele frequencies in the HSPB7 gene. | Association between polymorphisms of the HSPB7 gene and Cheyne-Stokes respiration with central sleep apnea in patients with dilated cardiomyopathy and congestive heart failure.
Wang M, Ding H, Kang J, Hu K, Lu W, Zhou X, Xu L. | 09/9/2017 |
| HSPB7 loci is associated in the pathophysiologuy of ischemic heart failure. | Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients.
Garnier S, Hengstenberg C, Lamblin N, Dubourg O, De Groote P, Fauchier L, Trochu JN, Arbustini E, Esslinger U, Barton PJ, Meder B, Katus H, Frese K, Komajda M, Cook SA, Isnard R, Tiret L, Villard E, Charron P. | 04/23/2016 |
| Results imply that HSBP7 is likely to be a tumor suppressor gene regulated by p53 and its downregulation by hypermethylation may play a critical role in renal carcinogenesis. | Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Lin J, Deng Z, Tanikawa C, Shuin T, Miki T, Matsuda K, Nakamura Y., Free PMC Article | 11/22/2014 |
| HSPB7 is a potential early biomarker after MI and serves as an independent risk factor of ACS in patients with acute chest pain. | Association of plasma concentration of small heat shock protein B7 with acute coronary syndrome.
Chiu TF, Li CH, Chen CC, Chen CH, Cheng CJ, Yan YT, Yang RB. | 02/2/2013 |
| Overexpression of HSPB1, as well as HSPB6, HSPB7 and HSPB8 independently protect against tachycardia remodeling by attenuation of the RhoA GTPase pathway at different levels. | HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes.
Ke L, Meijering RA, Hoogstra-Berends F, Mackovicova K, Vos MJ, Van Gelder IC, Henning RH, Kampinga HH, Brundel BJ., Free PMC Article | 11/5/2011 |
| Data show a significant association between a SNP in HSPB7 gene (rs1739843, minor allele frequency 39%) and idiopathic DCM. | Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy.
Stark K, Esslinger UB, Reinhard W, Petrov G, Winkler T, Komajda M, Isnard R, Charron P, Villard E, Cambien F, Tiret L, Aumont MC, Dubourg O, Trochu JN, Fauchier L, Degroote P, Richter A, Maisch B, Wichter T, Zollbrecht C, Grassl M, Schunkert H, Linsel-Nitschke P, Erdmann J, Baumert J, Illig T, Klopp N, Wichmann HE, Meisinger C, Koenig W, Lichtner P, Meitinger T, Schillert A, König IR, Hetzer R, Heid IM, Regitz-Zagrosek V, Hengstenberg C, Stark K, Esslinger UB, Reinhard W, Petrov G, Winkler T, Komajda M, Isnard R, Charron P, Villard E, Cambien F, Tiret L, Aumont MC, Dubourg O, Trochu JN, Fauchier L, Degroote P, Richter A, Maisch B, Wichter T, Zollbrecht C, Grassl M, Schunkert H, Linsel-Nitschke P, Erdmann J, Baumert J, Illig T, Klopp N, Wichmann HE, Meisinger C, Koenig W, Lichtner P, Meitinger T, Schillert A, König IR, Hetzer R, Heid IM, Regitz-Zagrosek V, Hengstenberg C., Free PMC Articles: PMC2958814, PMC2958814 | 03/12/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesGenetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy.
Stark K, Esslinger UB, Reinhard W, Petrov G, Winkler T, Komajda M, Isnard R, Charron P, Villard E, Cambien F, Tiret L, Aumont MC, Dubourg O, Trochu JN, Fauchier L, Degroote P, Richter A, Maisch B, Wichter T, Zollbrecht C, Grassl M, Schunkert H, Linsel-Nitschke P, Erdmann J, Baumert J, Illig T, Klopp N, Wichmann HE, Meisinger C, Koenig W, Lichtner P, Meitinger T, Schillert A, König IR, Hetzer R, Heid IM, Regitz-Zagrosek V, Hengstenberg C, Stark K, Esslinger UB, Reinhard W, Petrov G, Winkler T, Komajda M, Isnard R, Charron P, Villard E, Cambien F, Tiret L, Aumont MC, Dubourg O, Trochu JN, Fauchier L, Degroote P, Richter A, Maisch B, Wichter T, Zollbrecht C, Grassl M, Schunkert H, Linsel-Nitschke P, Erdmann J, Baumert J, Illig T, Klopp N, Wichmann HE, Meisinger C, Koenig W, Lichtner P, Meitinger T, Schillert A, König IR, Hetzer R, Heid IM, Regitz-Zagrosek V, Hengstenberg C. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. | 09/15/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| The rs1738943 shows that although this SNP is located within HSPB7, it resides in a block of high LD that spans HSPB7 and a nearby gene, CLCNKA, which encodes a voltage-sensitive chloride channel expressed mainly in the kidney. | Common variants in HSPB7 and FRMD4B associated with advanced heart failure.
Cappola TP, Li M, He J, Ky B, Gilmore J, Qu L, Keating B, Reilly M, Kim CE, Glessner J, Frackelton E, Hakonarson H, Syed F, Hindes A, Matkovich SJ, Cresci S, Dorn GW 2nd., Free PMC Article | 08/2/2010 |
| Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease. | Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.
Matkovich SJ, Van Booven DJ, Hindes A, Kang MY, Druley TE, Vallania FL, Mitra RD, Reilly MP, Cappola TP, Dorn GW 2nd., Free PMC Article | 01/25/2010 |
| HSPB7 constitutively localized to SC35 splicing speckles, driven by its N-terminus. Unlike HSPB1 and HSPB5, that chaperoned heat unfolded substrates and kept them folding competent, HSPB7 did not support refolding. | HSPB7 is a SC35 speckle resident small heat shock protein.
Vos MJ, Kanon B, Kampinga HH. | 01/21/2010 |