| [Mechanism of ring finger protein 11 regulating Akt signaling pathway to promote osteogenic differentiation of bone marrow mesenchymal stem cells]. | [Mechanism of ring finger protein 11 regulating Akt signaling pathway to promote osteogenic differentiation of bone marrow mesenchymal stem cells].
Deng W, Long T, Du Y., Free PMC Article | 01/22/2022 |
| Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism. | Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism.
Massart J, Sjögren RJO, Egan B, Garde C, Lindgren M, Gu W, Ferreira DMS, Katayama M, Ruas JL, Barrès R, O'Gorman DJ, Zierath JR, Krook A., Free PMC Article | 11/6/2021 |
| RNF11 at the Crossroads of Protein Ubiquitination. | RNF11 at the Crossroads of Protein Ubiquitination.
Mattioni A, Castagnoli L, Santonico E., Free PMC Article | 09/11/2021 |
| Ring Finger Protein 11 acts on ligand-activated EGFR via the direct interaction with the UIM region of ANKRD13 protein family. | Ring Finger Protein 11 acts on ligand-activated EGFR via the direct interaction with the UIM region of ANKRD13 protein family.
Mattioni A, Boldt K, Auciello G, Komada M, Rappoport JZ, Ueffing M, Castagnoli L, Cesareni G, Santonico E. | 05/22/2021 |
| miR-425-5p Acts as a Molecular Marker and Promoted Proliferation, Migration by Targeting RNF11 in Hepatocellular Carcinoma. | miR-425-5p Acts as a Molecular Marker and Promoted Proliferation, Migration by Targeting RNF11 in Hepatocellular Carcinoma.
Rao D, Guan S, Huang J, Chang Q, Duan S., Free PMC Article | 05/8/2021 |
| RNF11 may regulate the activity of E3s that rely on Ubc13 for ubiquitin chain assembly by limiting the availability of Ubc13 and its conjugate. | The RING domain of RING Finger 11 (RNF11) protein binds Ubc13 and inhibits formation of polyubiquitin chains.
Budhidarmo R, Zhu J, Middleton AJ, Day CL. | 02/23/2019 |
| data suggest for the first time that the choice of binding partners for SMURF2 can sustain or repress TGFbeta signaling, and RNF11 may promote TGFbeta-induced cell migration. | RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.
Malonis RJ, Fu W, Jelcic MJ, Thompson M, Canter BS, Tsikitis M, Esteva FJ, Sánchez I., Free PMC Article | 06/10/2017 |
| Up-regulation of COPII components requires the transcriptional regulator RNF11, which localizes to early endosomes and appears additionally in the cell nucleus upon continuous EGF stimulation. | The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R., Free PMC Article | 06/3/2017 |
| RNF11 is at the center of a finally regulated system where it acts both as an adaptor and a modulator of itch-mediated control of ubiquitination events underlying membrane traffic. | RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.
Santonico E, Mattioni A, Panni S, Belleudi F, Mattei M, Torrisi MR, Cesareni G, Castagnoli L. | 09/26/2015 |
| Our data exemplifies the relevance of RNF11 and persistent NF-kappaB activation in Parkinson's disease | NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease.
Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R., Free PMC Article | 01/18/2014 |
| The negative influence that perturbation of RNF11 and SARA levels exerts on the lysosomal degradation of EGFRs could underscore the significance of overexpression of RNF11 in certain cancers. | SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.
Kostaras E, Sflomos G, Pedersen NM, Stenmark H, Fotsis T, Murphy C. | 01/4/2014 |
| RNF11 functions together with TAX1BP1 to restrict antiviral signaling and IFN-beta production. | RING finger protein 11 targets TBK1/IKKi kinases to inhibit antiviral signaling.
Charoenthongtrakul S, Gao L, Parvatiyar K, Lee D, Harhaj EW., Free PMC Article | 07/6/2013 |
| RNF11 negatively regulates canonical NF-kappaB signaling in the nervous system. | Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling.
Pranski EL, Dalal NV, Herskowitz JH, Orr AL, Roesch LA, Fritz JJ, Heilman C, Lah JJ, Levey AI, Betarbet RS., Free PMC Article | 06/15/2013 |
| Microglial RNF11 is a negative regulator of NF-kappaB signalling pathway and could be a strong potential target for modulating inflammatory responses in neurodegenerative diseases. | RNF11 modulates microglia activation through NF-κB signalling cascade.
Dalal NV, Pranski EL, Tansey MG, Lah JJ, Levey AI, Betarbet RS., Free PMC Article | 12/22/2012 |
| Data show that membrane anchoring through acylation is necessary for RNF11 to be post-translationally modified by the addition of several ubiquitin moieties. | Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment.
Santonico E, Belleudi F, Panni S, Torrisi MR, Cesareni G, Castagnoli L. | 11/27/2010 |
| RNF11, together with TAX1BP1 and Itch, is an essential component of an A20 ubiquitin-editing protein complex that ensures transient activation of inflammatory signalling pathways. | The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling.
Shembade N, Parvatiyar K, Harhaj NS, Harhaj EW., Free PMC Article | 01/21/2010 |
| Analysis reveals that the main determinants of selectivity between ubiquitin ligases RNF11 and E2 ubiquitin-conjugating enzymes resides on ring domains, rather than on the E2s. | Analysis of electrostatic contributions to the selectivity of interactions between RING-finger domains and ubiquitin-conjugating enzymes.
Scheper J, Oliva B, Villà-Freixa J, Thomson TM. | 01/21/2010 |
| WWP1 may promote cell proliferation and survival partially through suppressing RNF11-mediated ErbB2 and EGFR downregulation in human cancer cells. | The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.
Chen C, Zhou Z, Liu R, Li Y, Azmi PB, Seth AK. | 01/21/2010 |
| these findings identify RNF11 as a strong candidate gene at the PARK10 locus and highlight its potential significance in the development of the common form of Parkinson disease | PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain.
Anderson LR, Betarbet R, Gearing M, Gulcher J, Hicks AA, Stefánsson K, Lah JJ, Levey AI. | 01/21/2010 |
| overexpression of RNF11, through its interaction with Smurf2, can restore TGFbeta responsiveness in transfected tumor cells | The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.
Subramaniam V, Li H, Wong M, Kitching R, Attisano L, Wrana J, Zubovits J, Burger AM, Seth A., Free PMC Article | 01/21/2010 |
| RNF11 is a small RING E3 ligase that affects transforming growth factorbeta and EGF-R signaling and is overexpressed in invasive breast cancers | Novel RING E3 ubiquitin ligases in breast cancer.
Burger A, Amemiya Y, Kitching R, Seth AK., Free PMC Article | 01/21/2010 |
| characterization of ring finger protein 11 | Molecular characterization of ring finger protein 11.
Connor MK, Azmi PB, Subramaniam V, Li H, Seth A. | 01/21/2010 |