| NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway. | NUPR1 induces autophagy and promotes the progression of Esophageal squamous cell carcinoma via the MAPK-mTOR pathway.
Ren S, Chen Y, Wang Q, Song L, Xin Z, Shi M, Liu X. | 05/29/2024 |
| WTAP Mediates NUPR1 Regulation of LCN2 Through m[6]A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion. | WTAP Mediates NUPR1 Regulation of LCN2 Through m(6)A Modification to Influence Ferroptosis, Thereby Promoting Breast Cancer Proliferation, Migration and Invasion.
Tan M, He Y, Yi J, Chen J, Guo Q, Liao N, Peng L. | 04/25/2024 |
| SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest. | SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest.
Wang C, Wang T, Li KJ, Hu LH, Li Y, Yu YZ, Xie T, Zhu S, Fu DJ, Wang Y, Zeng XZ, Liu FP, Chen H, Chen ZS, Feng NH, Liu J, Jiang Y, Zhao SC. | 11/30/2023 |
| [Mechanism of nuclear protein 1 in the resistance to axitinib in clear cell renal cell carcinoma]. | [Mechanism of nuclear protein 1 in the resistance to axitinib in clear cell renal cell carcinoma].
Liu YC, Wu ZL, Ge LY, DU T, Wu YQ, Song YM, Liu C, Ma LL., Free PMC Article | 11/3/2023 |
| Nuclear protein-1 is the common link for pathways activated by aging and obesity in chondrocytes: A potential therapeutic target for osteoarthritis. | Nuclear protein-1 is the common link for pathways activated by aging and obesity in chondrocytes: A potential therapeutic target for osteoarthritis.
Tan L, Armstrong AR, Rosas S, Patel CM, Vander Wiele SS, Willey JS, Carlson CS, Yammani RR., Free PMC Article | 08/17/2023 |
| NUPR1 imparts oncogenic potential in bladder cancer. | NUPR1 imparts oncogenic potential in bladder cancer.
Zhang L, Gao S, Shi X, Chen Y, Wei S, Mi Y, Zuo L, Qi C., Free PMC Article | 04/5/2023 |
| NUPR1 promotes the proliferation and migration of breast cancer cells by activating TFE3 transcription to induce autophagy. | NUPR1 promotes the proliferation and migration of breast cancer cells by activating TFE3 transcription to induce autophagy.
Xiao H, Long J, Chen X, Tan MD. | 07/23/2022 |
| Knockdown of NUPR1 Enhances the Sensitivity of Non-small-cell Lung Cancer Cells to Metformin by AKT Inhibition. | Knockdown of NUPR1 Enhances the Sensitivity of Non-small-cell Lung Cancer Cells to Metformin by AKT Inhibition.
Kim YJ, Hong SE, Jang SK, Park KS, Kim CH, Park IC, Jin HO. | 07/9/2022 |
| NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy. | NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy.
Fan T, Wang X, Zhang S, Deng P, Jiang Y, Liang Y, Jie S, Wang Q, Li C, Tian G, Zhang Z, Ren Z, Li B, Chen Y, He Z, Luo Y, Chen M, Wu H, Yu Z, Pi H, Zhou Z, Zhang Z., Free PMC Article | 05/14/2022 |
| Histone methyltransferase Dot1L inhibits pancreatic cancer cell apoptosis by promoting NUPR1 expression. | Histone methyltransferase Dot1L inhibits pancreatic cancer cell apoptosis by promoting NUPR1 expression.
Shan L, Hao C, Jun Z, Qinghe C., Free PMC Article | 04/9/2022 |
| Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function. | Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function.
Rizzuti B, Lan W, Santofimia-Castaño P, Zhou Z, Velázquez-Campoy A, Abián O, Peng L, Neira JL, Xia Y, Iovanna JL., Free PMC Article | 01/22/2022 |
| The NUPR1/p73 axis contributes to sorafenib resistance in hepatocellular carcinoma. | The NUPR1/p73 axis contributes to sorafenib resistance in hepatocellular carcinoma.
Augello G, Emma MR, Azzolina A, Puleio R, Condorelli L, Cusimano A, Giannitrapani L, McCubrey JA, Iovanna JL, Cervello M. | 01/8/2022 |
| microRNA-637 promotes apoptosis and suppresses proliferation and autophagy in multiple myeloma cell lines via NUPR1. | microRNA-637 promotes apoptosis and suppresses proliferation and autophagy in multiple myeloma cell lines via NUPR1.
Chen X, Li A, Zhan Q, Jing Z, Chen Y, Chen J., Free PMC Article | 12/18/2021 |
| Trifluoperazine induces cellular apoptosis by inhibiting autophagy and targeting NUPR1 in multiple myeloma. | Trifluoperazine induces cellular apoptosis by inhibiting autophagy and targeting NUPR1 in multiple myeloma.
Li A, Chen X, Jing Z, Chen J., Free PMC Article | 11/27/2021 |
| NUPR1 participates in YAP-mediate gastric cancer malignancy and drug resistance via AKT and p21 activation. | NUPR1 participates in YAP-mediate gastric cancer malignancy and drug resistance via AKT and p21 activation.
Jiang L, Wang W, Li Z, Zhao Y, Qin Z. | 11/13/2021 |
| NUPR1 and its potential role in cancer and pathological conditions (Review). | NUPR1 and its potential role in cancer and pathological conditions (Review).
Martin TA, Li AX, Sanders AJ, Ye L, Frewer K, Hargest R, Jiang WG. | 11/6/2021 |
| Induction of NUPR1 and AP1 contributes to the carcinogenic potential of nickel. | Induction of NUPR1 and AP‑1 contributes to the carcinogenic potential of nickel.
Murphy A, Roy N, Sun H, Jin C, Costa M., Free PMC Article | 10/30/2021 |
| Transcriptional coregualtor NUPR1 maintains tamoxifen resistance in breast cancer cells. | Transcriptional coregualtor NUPR1 maintains tamoxifen resistance in breast cancer cells.
Wang L, Sun J, Yin Y, Sun Y, Ma J, Zhou R, Chang X, Li D, Yao Z, Tian S, Zhang K, Liu Z, Ma Z., Free PMC Article | 09/18/2021 |
| Single-Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells. | Single-Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells.
Schnepp PM, Shelley G, Dai J, Wakim N, Jiang H, Mizokami A, Keller ET., Free PMC Article | 08/14/2021 |
| NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response. | NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response.
Teresa Borrello M, Rita Emma M, Listi A, Rubis M, Coslet S, Augello G, Cusimano A, Cabibi D, Porcasi R, Giannitrapani L, Soresi M, Pantuso G, Blyth K, Montalto G, Pin C, Cervello M, Iovanna J. | 07/31/2021 |
| NUPR1 is a novel potential biomarker and confers resistance to sorafenib in clear cell renal cell carcinoma by increasing stemness and targeting the PTEN/AKT/mTOR pathway. | NUPR1 is a novel potential biomarker and confers resistance to sorafenib in clear cell renal cell carcinoma by increasing stemness and targeting the PTEN/AKT/mTOR pathway.
He W, Cheng F, Zheng B, Wang J, Zhao G, Yao Z, Zhang T., Free PMC Article | 07/24/2021 |
| A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin. | A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin.
Neira JL, Rizzuti B, Jiménez-Alesanco A, Palomino-Schätzlein M, Abián O, Velázquez-Campoy A, Iovanna JL., Free PMC Article | 06/26/2021 |
| Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells. | Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells.
Ko EJ, Ock MS, Choi YH, Iovanna JL, Mun S, Han K, Kim HS, Cha HJ., Free PMC Article | 05/15/2021 |
| Inhibition of NUPR1-Karyopherin beta1 Binding Increases Anticancer Drug Sensitivity. | Inhibition of NUPR1-Karyopherin β1 Binding Increases Anticancer Drug Sensitivity.
Park C, Oh J, Lee WM, Koh HR, Sohn UD, Ham SW, Oh K., Free PMC Article | 05/8/2021 |
| Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1. | Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1.
Santofimia-Castaño P, Rizzuti B, Pey AL, Fárez-Vidal ME, Iovanna JL, Neira JL. | 04/17/2021 |