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    ZBTB20 zinc finger and BTB domain containing 20 [ Homo sapiens (human) ]

    Gene ID: 26137, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    [Le miR-224-5p regule sert de biomarqueur pour l'insuffisance hepatique aigue pediatrique et regule l'inflammation en modulant ZBTB20].

    [Le miR-224-5p régulé sert de biomarqueur pour l'insuffisance hépatique aiguë pédiatrique et régule l'inflammation en modulant ZBTB20].
    Wang Q, Zhang G, Zhang M, Zhang Y, Ruan L, Hao H.

    04/25/2024
    Zinc Finger and BTB Domain-Containing 20: A Newly Emerging Player in Pathogenesis and Development of Human Cancers.

    Zinc Finger and BTB Domain-Containing 20: A Newly Emerging Player in Pathogenesis and Development of Human Cancers.
    Liu J, Zhang H., Free PMC Article

    02/28/2024
    Transcription Factor Zbtb20 as a Regulator of Malignancy and Its Practical Applications.

    Transcription Factor Zbtb20 as a Regulator of Malignancy and Its Practical Applications.
    Stoyanov D, Stoyanov GS, Ivanov MN, Spasov RH, Tonchev AB., Free PMC Article

    09/30/2023
    Circ_0001602 aggravates the progression of acute myeloid leukemia by regulating the miR-192-5p/ZBTB20 axis.

    Circ_0001602 aggravates the progression of acute myeloid leukemia by regulating the miR-192-5p/ZBTB20 axis.
    Wu W, Deng J, Chen C, Ma X, Yu L, Chen L.

    08/19/2023
    The long non-coding RNA KLF3-AS1/miR-10a-3p/ZBTB20 axis improves the degenerative changes in human nucleus pulposus cells.

    The long non-coding RNA KLF3-AS1/miR-10a-3p/ZBTB20 axis improves the degenerative changes in human nucleus pulposus cells.
    Chen S, Zhuang Q, Li P, Zeng J, Peng Y, Ding Z, Cao H, Zheng R, Wang W.

    07/6/2023
    Spatial control of astrogenesis progression by cortical arealization genes.

    Spatial control of astrogenesis progression by cortical arealization genes.
    Santo M, Rigoldi L, Falcone C, Tuccillo M, Calabrese M, Martínez-Cerdeño V, Mallamaci A.

    03/21/2023
    Circ-SFMBT2 facilitates the malignant growth of acute myeloid leukemia cells by modulating miR-582-3p/ZBTB20 pathway.

    Circ-SFMBT2 facilitates the malignant growth of acute myeloid leukemia cells by modulating miR-582-3p/ZBTB20 pathway.
    Chang W, Shang Z, Ming X, Wu J, Xiao Y.

    04/16/2022
    An association study in the Taiwan Biobank elicits three novel candidates for cognitive aging in old adults: NCAM1, TTC12 and ZBTB20.

    An association study in the Taiwan Biobank elicits three novel candidates for cognitive aging in old adults: NCAM1, TTC12 and ZBTB20.
    Lin E, Kuo PH, Lin WY, Liu YL, Yang AC, Tsai SJ., Free PMC Article

    12/11/2021
    LncRNA SNHG8 promotes cell migration and invasion in breast cancer cell through miR-634/ZBTB20 axis.

    LncRNA SNHG8 promotes cell migration and invasion in breast cancer cell through miR-634/ZBTB20 axis.
    Fan D, Qiu B, Yang XJ, Tang HL, Peng SJ, Yang P, Dong YM, Yang L, Bao GQ, Zhao HD.

    07/3/2021
    Primrose syndrome: Characterization of the phenotype in 42 patients.

    Primrose syndrome: Characterization of the phenotype in 42 patients.
    Melis D, Carvalho D, Barbaro-Dieber T, Espay AJ, Gambello MJ, Gener B, Gerkes E, Hitzert MM, Hove HB, Jansen S, Jira PE, Lachlan K, Menke LA, Narayanan V, Ortiz D, Overwater E, Posmyk R, Ramsey K, Rossi A, Sandoval RL, Stumpel C, Stuurman KE, Cordeddu V, Turnpenny P, Strisciuglio P, Tartaglia M, Unger S, Waters T, Turnbull C, Hennekam RC., Free PMC Article

    06/5/2021
    Primrose syndrome: a phenotypic comparison of patients with a ZBTB20 missense variant versus a 3q13.31 microdeletion including ZBTB20.

    Primrose syndrome: a phenotypic comparison of patients with a ZBTB20 missense variant versus a 3q13.31 microdeletion including ZBTB20.
    Juven A, Nambot S, Piton A, Jean-Marçais N, Masurel A, Callier P, Marle N, Mosca-Boidron AL, Kuentz P, Philippe C, Chevarin M, Duffourd Y, Gautier E, Munnich A, Rio M, Rondeau S, El Chehadeh S, Schaefer É, Gérard B, Bouquillon S, Delorme CV, Francannet C, Laffargue F, Gouas L, Isidor B, Vincent M, Blesson S, Giuliano F, Pichon O, Le Caignec C, Journel H, Perrin-Sabourin L, Fabre-Teste J, Martin D, Vieville G, Dieterich K, Lacombe D, Denommé-Pichon AS, Thauvin-Robinet C, Faivre L., Free PMC Article

    06/5/2021
    The diagnostic challenges and clinical course of a myeloid/lymphoid neoplasm with eosinophilia and ZBTB20-JAK2 gene fusion presenting as B-lymphoblastic leukemia.

    The diagnostic challenges and clinical course of a myeloid/lymphoid neoplasm with eosinophilia and ZBTB20-JAK2 gene fusion presenting as B-lymphoblastic leukemia.
    Lee WY, Pfau RB, Choi SM, Yang J, Xiao H, Putnam EM, Ryan RJ, Bixby DL, Shao L., Free PMC Article

    05/29/2021
    ZBTB20 Positively Regulates Oxidative Stress, Mitochondrial Fission, and Inflammatory Responses of ox-LDL-Induced Macrophages in Atherosclerosis.

    ZBTB20 Positively Regulates Oxidative Stress, Mitochondrial Fission, and Inflammatory Responses of ox-LDL-Induced Macrophages in Atherosclerosis.
    Tao J, Qiu J, Lu L, Zhang L, Fu Y, Wang M, Han J, Shi M, Li L, Zhao Z, Wei F, Wang C, Zhang H, Liang S, Zheng J., Free PMC Article

    05/22/2021
    Prediction of gastric cancer risk: association between ZBTB20 genetic variance and gastric cancer risk in Chinese Han population.

    Prediction of gastric cancer risk: association between ZBTB20 genetic variance and gastric cancer risk in Chinese Han population.
    Bai F, Xiao K., Free PMC Article

    04/3/2021
    HBV DNA integrates into upregulated ZBTB20 in patients with hepatocellular carcinoma.

    HBV DNA integrates into upregulated ZBTB20 in patients with hepatocellular carcinoma.
    He Z, Zhu J, Mo J, Zhao H, Chen Q., Free PMC Article

    02/20/2021
    Primrose syndrome associated with unclassified immunodeficiency and a novel ZBTB20 mutation.

    Primrose syndrome associated with unclassified immunodeficiency and a novel ZBTB20 mutation.
    Yamamoto-Shimojima K, Imaizumi T, Akagawa H, Kanno H, Yamamoto T.

    01/9/2021
    Long non-coding RNA LINC00641 promotes cell growth and migration through modulating miR-378a/ZBTB20 axis in acute myeloid leukemia.

    Long non-coding RNA LINC00641 promotes cell growth and migration through modulating miR-378a/ZBTB20 axis in acute myeloid leukemia.
    Wang J, Liu ZH, Yu LJ.

    10/10/2020
    an important role for ZBTB20 in controlling gastric cancer development

    ZBTB20 promotes cell migration and invasion of gastric cancer by inhibiting IκBα to induce NF-κB activation.
    Zhang Y, Zhou X, Zhang M, Cheng L, Zhang Y, Wang X.

    02/22/2020
    Our data document that both mutations have dominant negative impact on wild-type ZBTB20, providing further evidence of the specific behavior of Primrose syndrome (PS)-causing mutations on ZBTB20 function.

    Clinical and functional characterization of two novel ZBTB20 mutations causing Primrose syndrome.
    Stellacci E, Steindl K, Joset P, Mercurio L, Anselmi M, Cecchetti S, Gogoll L, Zweier M, Hackenberg A, Bocchinfuso G, Stella L, Tartaglia M, Rauch A.

    06/15/2019
    we report novel de novo ZBTB20 mutations in three independent cases with characteristic features of Primrose syndrome including constant CCA.

    Novel de novo ZBTB20 mutations in three cases with Primrose syndrome and constant corpus callosum anomalies.
    Alby C, Boutaud L, Bessières B, Serre V, Rio M, Cormier-Daire V, de Oliveira J, Ichkou A, Mouthon L, Gordon CT, Bonnière M, Mechler C, Nitschke P, Bole C, Lyonnet S, Bahi-Buisson N, Boddaert N, Colleaux L, Roth P, Ville Y, Vekemans M, Encha-Razavi F, Attié-Bitach T, Thomas S.

    05/25/2019
    ZBTB20 is a candidate susceptibility gene for seasonal affective disorder

    Genome-wide association study of seasonal affective disorder.
    Ho KWD, Han S, Nielsen JV, Jancic D, Hing B, Fiedorowicz J, Weissman MM, Levinson DF, Potash JB., Free PMC Article

    03/16/2019
    Two ZBTB20 single nucleotide variants, located at the N-terminal and central regions of the protein and potentially conferring autism risk, altered dendritic spine morphology. In contrast, a single nucleotide variant identified in patients with intellectual disability and located at the C-terminus of ZBTB20 affected dendritic arborization and dendritic length but had no effect on dendritic spine morphology

    Neurodevelopmental disorder-associated ZBTB20 gene variants affect dendritic and synaptic structure.
    Jones KA, Luo Y, Dukes-Rimsky L, Srivastava DP, Koul-Tewari R, Russell TA, Shapiro LP, Srivastava AK, Penzes P., Free PMC Article

    03/9/2019
    ZBTB20 knockdown inhibited glioblastoma cell proliferation, migration, and invasion.

    Mir-758-5p Suppresses Glioblastoma Proliferation, Migration and Invasion by Targeting ZBTB20.
    Liu J, Jiang J, Hui X, Wang W, Fang D, Ding L.

    09/15/2018
    High ZBTB20 expression is associated with hepatocellular carcinoma.

    Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1.
    Kan H, Huang Y, Li X, Liu D, Chen J, Shu M., Free PMC Article

    12/16/2017
    We report a boy with intellectual disability carrying two de novo missense mutations in the last exon of ZBTB20 (Ser616Phe and Gly741Arg; both previously unreported). One of them, Ser616Phe, affects an amino acid located in one of the C2H2 zing-fingers involved in DNA-binding and close to other missense mutations already described. Reverse phenotyping showed that this patient presents with classic features of Primrose syn

    Novel de novo mutations in ZBTB20 in Primrose syndrome with congenital hypothyroidism.
    Mattioli F, Piton A, Gérard B, Superti-Furga A, Mandel JL, Unger S.

    10/28/2017
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