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    RAB11FIP5 RAB11 family interacting protein 5 [ Homo sapiens (human) ]

    Gene ID: 26056, updated on 6-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.

    Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.
    Fan X, Zhou D, Zhao B, Sha H, Li M, Li X, Yang J, Yan H., Free PMC Article

    11/13/2021
    RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures.

    RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures.
    Li D, Bradley T, Cain DW, Pedroza-Pacheco I, Aggelakopoulou M, Parks R, Barr M, Xia SM, Scearce R, Bowman C, Stevens G, Newman A, Hora B, Chen Y, Riebe K, Wang Y, Sempowski G, Saunders KO, Borrow P, Haynes BF., Free PMC Article

    11/13/2021
    Host RAB11FIP5 protein inhibits the release of Kaposi's sarcoma-associated herpesvirus particles by promoting lysosomal degradation of ORF45.

    Host RAB11FIP5 protein inhibits the release of Kaposi's sarcoma-associated herpesvirus particles by promoting lysosomal degradation of ORF45.
    Wei X, Dong J, Cheng CC, Ji M, Yu L, Luo S, Wu S, Bai L, Lan K., Free PMC Article

    02/2/2021
    The Rab-binding module of FERARI (factors for endosome recycling and Rab interactions) consists of Rab11FIP5 and rabenosyn-5, while the SNARE-interacting module comprises VPS45 and VIPAS39.

    FERARI is required for Rab11-dependent endocytic recycling.
    Solinger JA, Rashid HO, Prescianotto-Baschong C, Spang A.

    04/18/2020
    FIP5-T276 phosphorylation occurs specifically during metaphase and anaphase.

    FIP5 phosphorylation during mitosis regulates apical trafficking and lumenogenesis.
    Li D, Mangan A, Cicchini L, Margolis B, Prekeris R., Free PMC Article

    11/29/2014
    FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells.

    Interaction between FIP5 and SNX18 regulates epithelial lumen formation.
    Willenborg C, Jing J, Wu C, Matern H, Schaack J, Burden J, Prekeris R., Free PMC Article

    11/19/2011
    These data introduce Rab11b as a crucial regulator and Rip11 as mediator of acidosis-induced V-ATPase traffic in duct cells of submandibular gland.

    Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts.
    Oehlke O, Martin HW, Osterberg N, Roussa E.

    01/29/2011
    Observational study of gene-disease association. (HuGE Navigator)

    Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
    Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ., Free PMC Article

    12/5/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    Rip11/FIP5-kinesin-II complex plays a key role in the routing of internalized receptors through the perinuclear recycling endosomes.

    The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling.
    Schonteich E, Wilson GM, Burden J, Hopkins CR, Anderson K, Goldenring JR, Prekeris R., Free PMC Article

    01/21/2010
    analysis of the rearrangement breakpoints suggests that the reciprocal translocation may have formed secondary to incorrect repair of double strand breaks (DSBs) by nonhomologous end-joining (NHEJ).

    A de novo apparently balanced translocation [46,XY,t(2;9)(p13;p24)] interrupting RAB11FIP5 identifies a potential candidate gene for autism spectrum disorder.
    Roohi J, Tegay DH, Pomeroy JC, Burkett S, Stone G, Stanyon R, Hatchwell E., Free PMC Article

    01/21/2010
    These data therefore show that (i) Rab11a regulates cell surface abundance of both GLUT4 and FAT/CD36.

    FIP2 and Rip11 specify Rab11a-mediated cellular distribution of GLUT4 and FAT/CD36 in H9c2-hIR cells.
    Schwenk RW, Luiken JJ, Eckel J.

    01/21/2010
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