| CEBPD aggravates apoptosis and oxidative stress of neuron after ischemic stroke by Nrf2/HO-1 pathway. | CEBPD aggravates apoptosis and oxidative stress of neuron after ischemic stroke by Nrf2/HO-1 pathway.
Chen N, Xu Y, Liu Y, Zhao H, Liu R, Zhang Z. | 07/19/2024 |
| Four upregulated transcription factors Pax6, Tp73, Cebpd, and Spi1, appeared as potent regulators of chronic post-traumatic brain injury (TBI) gene expression. They regulate molecular networks contributing to post-injury secondary damage, including apoptosis and inflammation, strengthening the feasibility of therapeutically targeting these molecular networks even after the acute post-TBI period. | Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury.
Lipponen A, El-Osta A, Kaspi A, Ziemann M, Khurana I, Kn H, Navarro-Ferrandis V, Puhakka N, Paananen J, Pitkänen A., Free PMC Article | 09/22/2018 |
| DHT activated AR inhibits gene transactivation by C/EBPdelta, and transgenic C/EBPdelta expression inhibits AR activity | Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ.
McCarthy TL, Centrella M. | 12/19/2015 |
| novel function of C/EBPdelta as a modulatory transcription factor that inhibits the pro-apoptotic and pro-inflammatory gene networks activated by cytokines in pancreatic beta-cells. | The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
Moore F, Santin I, Nogueira TC, Gurzov EN, Marselli L, Marchetti P, Eizirik DL., Free PMC Article | 09/5/2014 |
| C/EBPdelta plays a critical role in both memory consolidation and reconsolidation. | CCAAT enhancer binding protein δ plays an essential role in memory consolidation and reconsolidation.
Arguello AA, Ye X, Bozdagi O, Pollonini G, Tronel S, Bambah-Mukku D, Huntley GW, Platano D, Alberini CM., Free PMC Article | 04/27/2013 |
| The results show that PRL expression and cell proliferation are controlled in part by CEBPD. | CEBPD suppresses prolactin expression and prolactinoma cell proliferation.
Tong Y, Zhou J, Mizutani J, Fukuoka H, Ren SG, Gutierrez-Hartmann A, Koeffler HP, Melmed S., Free PMC Article | 05/19/2012 |
| These data suggest that both expression and function of C/EBPdelta are dysregulated in Alzheimer's disease. | The CCAAT/enhancer binding protein (C/EBP) δ is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-β peptide.
Ramberg V, Tracy LM, Samuelsson M, Nilsson LN, Iverfeldt K., Free PMC Article | 09/3/2011 |
| Increase of plasma glucose is related to the lower expression of C/EBPbeta and C/EBPdelta proteins in the lung of STZ-diabetic rats. | Changes of CCAAT enhancer-binding proteins (CEBPs) in the lung of streptozotocin-induced diabetic rats.
Fong Y, Shen KH, Chen LJ, Cheng JT. | 07/16/2011 |
| CCAAT enhancer-binding protein isoforms have distinct functions in the regulation of manganese superoxide dismutase during interleukin-1beta stimulation | Distinct functions of CCAAT enhancer-binding protein isoforms in the regulation of manganese superoxide dismutase during interleukin-1beta stimulation.
Qiu X, Aiken KJ, Chokas AL, Beachy DE, Nick HS., Free PMC Article | 01/21/2010 |
| that interactions between C/EBPs and HDAC1 negatively regulate C/EBPdelta-dependent haptoglobin expression in intestinal epithelial cells. | Regulation of C/EBPdelta-dependent transactivation by histone deacetylases in intestinal epithelial cells.
Turgeon N, Valiquette C, Blais M, Routhier S, Seidman EG, Asselin C. | 01/21/2010 |
| Prostaglandin E2 increases transforming growth factor-beta type III receptor expression through CCAAT enhancer-binding protein delta in osteoblasts | Prostaglandin E2 increases transforming growth factor-beta type III receptor expression through CCAAT enhancer-binding protein delta in osteoblasts.
McCarthy TL, Pham TH, Knoll BI, Centrella M. | 01/21/2010 |
| Role of this C/EBP in the mechanism of upregulation of CCL2, an inflammation-related protein, observed in the hyperinsulinaemic state, which may initiate the process of atherosclerosis. | Increased expression of CCAAT/enhancer binding protein-beta and -delta and monocyte chemoattractant protein-1 genes in aortas from hyperinsulinaemic rats.
Sato Y, Nishio Y, Sekine O, Kodama K, Nagai Y, Nakamura T, Maegawa H, Kashiwagi A. | 01/21/2010 |
| Role for CCAAT/enhancing binding protein delta in the regulation of inducible nitric oxide synthase gene expression in glial cells. | The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein.
Won JS, Im YB, Key L, Singh I, Singh AK., Free PMC Article | 01/21/2010 |
| C/EBP-delta is induced by gp130 signaling | C/EBP-delta induction by gp130 signaling. Role in transition to myelin gene expressing phenotype in a melanoma cell line model.
Kamaraju AK, Adjalley S, Zhang P, Chebath J, Revel M. | 01/21/2010 |
| CEBPB and CEBPD regulate PI3K inflammatory gene expression | Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.
Sekine O, Nishio Y, Egawa K, Nakamura T, Maegawa H, Kashiwagi A. | 01/21/2010 |
| glucocorticoids increase C/EBPbeta and delta activity and expression through a direct effect in skeletal muscle | Expression and activity of C/EBPbeta and delta are upregulated by dexamethasone in skeletal muscle.
Yang H, Mammen J, Wei W, Menconi M, Evenson A, Fareed M, Petkova V, Hasselgren PO. | 01/21/2010 |
| C/EBPdelta has a role in abolishing CBP phosphorylation as well as transcriptional activation and could be important in C/EBP-mediated transcription | CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation.
Kovács KA, Steinmann M, Magistretti PJ, Halfon O, Cardinaux JR. | 01/21/2010 |
| multiple domains of C/EBPdelta and ERalpha can physically interact to alter gene expression in osteoblasts in selective ways that depend on variations in the local hormone environment. | Interactions between CCAAT enhancer binding protein delta and estrogen receptor alpha control insulin-like growth factor I (igf1) and estrogen receptor-dependent gene expression in osteoblasts.
Chang W, Parra M, Centrella M, McCarthy TL. | 01/21/2010 |
| CEBPd has a role in regulating lipogenic enzymes and transport proteins stimulated by keratinocyte growth factor in type II alveolar cells | Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells.
Mason RJ, Pan T, Edeen KE, Nielsen LD, Zhang F, Longphre M, Eckart MR, Neben S., Free PMC Article | 01/21/2010 |
| critical role for C/EBPdelta in regional expression of NGF in the brain implicating CREB | CAAT/enhancer-binding protein delta and cAMP-response element-binding protein mediate inducible expression of the nerve growth factor gene in the central nervous system.
McCauslin CS, Heath V, Colangelo AM, Malik R, Lee S, Mallei A, Mocchetti I, Johnson PF. | 01/21/2010 |
| C/EBP-delta was induced in the mesangial region during the early stages of anti-Thy1.1 glomerulonephritis. C/EBP-delta contributes to inflammatory gene expression and MC proliferation. | CCAAT/enhancer-binding protein-delta is induced in mesangial area during the early stages of anti-Thy1.1 glomerulonephritis and regulates cell proliferation and inflammatory gene expression in cultured rat mesangial cells.
Miyoshi K, Okura T, Fukuoka T, Higaki J. | 01/21/2010 |