[Primary pulmonary NUT carcinoma: a clinicopathological analysis of seven cases]. | [Primary pulmonary NUT carcinoma: a clinicopathological analysis of seven cases]. Zhuang XP, Huang HJ, Chen X, Zheng SL, Li BC, Sun H. | 12/18/2023 |
The expanding universe of NUTM1 fusions in pediatric cancer. | The expanding universe of NUTM1 fusions in pediatric cancer. Charlab R, Racz R., Free PMC Article | 08/23/2023 |
NUT Carcinoma in Children and Adolescents: The Expert European Standard Clinical Practice Harmonized Recommendations. | NUT Carcinoma in Children and Adolescents: The Expert European Standard Clinical Practice Harmonized Recommendations. Lemelle L, Flaadt T, Fresneau B, Moya-Plana A, Timmermann B, Roganovic J, Ferrari A, Fichera G, Lauer UM, Ben-Ami T, Schneider DT, Vokuhl C, Bolle S, Fox E, DuBois SG, Rodriguez-Galindo C, Bisogno G, Surun A, Brecht IB, Orbach D. | 04/26/2023 |
Structural mechanism of BRD4-NUT and p300 bipartite interaction in propagating aberrant gene transcription in chromatin in NUT carcinoma. | Structural mechanism of BRD4-NUT and p300 bipartite interaction in propagating aberrant gene transcription in chromatin in NUT carcinoma. Yu D, Liang Y, Kim C, Jaganathan A, Ji D, Han X, Yang X, Jia Y, Gu R, Wang C, Zhang Q, Cheung KL, Zhou MM, Zeng L., Free PMC Article | 02/4/2023 |
Clinicopathologic features of an MXI1::NUTM1 fusion neoplasm; a new molecular variant of the family of NUTM1-rearranged neoplasm. | Clinicopathologic features of an MXI1::NUTM1 fusion neoplasm; a new molecular variant of the family of NUTM1-rearranged neoplasm. Duan FL, Hou J, Guo P, Tan H, Dai J, Tang Z, Chen M, Liu Y. | 10/29/2022 |
NUT carcinoma, an under-recognized malignancy: a clinicopathologic and molecular series of 6 cases showing a subset of patients with better prognosis and a rare ZNF532::NUTM1 fusion. | NUT carcinoma, an under-recognized malignancy: a clinicopathologic and molecular series of 6 cases showing a subset of patients with better prognosis and a rare ZNF532::NUTM1 fusion. Abreu RF, Oliveira TB, Hertzler H, Toledo RN, D'Almeida Costa F, Lopes Pinto CA, Nunes WA, Nascimento AF, French CA, Nascimento AG. | 08/20/2022 |
CIC-NUTM1 Sarcomas Affecting the Spine. | CIC-NUTM1 Sarcomas Affecting the Spine. Yang S, Liu L, Yan Y, Jiang L, Han S, Shen D, Zhang B. | 06/11/2022 |
NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion. | NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion. Chen M, Zhao S, Liang Z, Wang W, Zhou P, Jiang L. | 04/30/2022 |
NUTM1-rearranged colorectal sarcoma: a clinicopathologically and genetically distinctive malignant neoplasm with a poor prognosis. | NUTM1-rearranged colorectal sarcoma: a clinicopathologically and genetically distinctive malignant neoplasm with a poor prognosis. Van Treeck BJ, Thangaiah JJ, Torres-Mora J, Stevens TM, Rothermundt C, Fassan M, Loupakis F, Diebold J, Hornick JL, Halling KC, Folpe AL. | 01/29/2022 |
Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study. | Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study. Boer JM, Valsecchi MG, Hormann FM, Antić Ž, Zaliova M, Schwab C, Cazzaniga G, Arfeuille C, Cavé H, Attarbaschi A, Strehl S, Escherich G, Imamura T, Ohki K, Grüber TA, Sutton R, Pastorczak A, Lammens T, Lambert F, Li CK, Carrillo de Santa Pau E, Hoffmann S, Möricke A, Harrison CJ, Den Boer ML, De Lorenzo P, Stam RW, Bergmann AK, Pieters R., Free PMC Article | 01/1/2022 |
Thoracic nuclear protein in testis (NUT) carcinoma: expanded pathological spectrum with expression of thyroid transcription factor-1 and neuroendocrine markers. | Thoracic nuclear protein in testis (NUT) carcinoma: expanded pathological spectrum with expression of thyroid transcription factor-1 and neuroendocrine markers. Hung YP, Chen AL, Taylor MS, Huynh TG, Kem M, Selig MK, Nielsen GP, Lennerz JK, Azzoli CG, Dagogo-Jack I, Kradin RL, Mino-Kenudson M. | 11/22/2021 |
NUT Is a Specific Immunohistochemical Marker for the Diagnosis of YAP1-NUTM1-rearranged Cutaneous Poroid Neoplasms. | NUT Is a Specific Immunohistochemical Marker for the Diagnosis of YAP1-NUTM1-rearranged Cutaneous Poroid Neoplasms. Macagno N, Kervarrec T, Sohier P, Poirot B, Haffner A, Carlotti A, Balme B, Castillo C, Jullie ML, Osio A, Lehmann-Che J, Frouin E, Battistella M. | 11/22/2021 |
YAP1-NUTM1 Gene Fusion in Porocarcinoma of the External Auditory Canal. | YAP1-NUTM1 Gene Fusion in Porocarcinoma of the External Auditory Canal. Agaimy A, Tögel L, Haller F, Zenk J, Hornung J, Märkl B., Free PMC Article | 09/18/2021 |
Supercharging BRD4 with NUT in carcinoma. | Supercharging BRD4 with NUT in carcinoma. Eagen KP, French CA., Free PMC Article | 07/31/2021 |
Challenges and Opportunities in NUT Carcinoma Research. | Challenges and Opportunities in NUT Carcinoma Research. Hakun MC, Gu B., Free PMC Article | 07/24/2021 |
YAP1-MAML2 and YAP1-NUTM1 fusions have roles in poroma and porocarcinoma | Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma. Sekine S, Kiyono T, Ryo E, Ogawa R, Wakai S, Ichikawa H, Suzuki K, Arai S, Tsuta K, Ishida M, Sasajima Y, Goshima N, Yamazaki N, Mori T., Free PMC Article | 06/27/2020 |
Our results confirm that NUTM1 gene rearrangements are found outside the classic clinicopathological setting of NUT carcinoma | NUTM1-rearranged neoplasia: a multi-institution experience yields novel fusion partners and expands the histologic spectrum. Stevens TM, Morlote D, Xiu J, Swensen J, Brandwein-Weber M, Miettinen MM, Gatalica Z, Bridge JA., Free PMC Article | 04/25/2020 |
CIC-NUTM1 sarcomas represent a new molecular variant of CIC-fused sarcomas with a predilection for the central nervous system and younger pediatric population | Clinicopathologic Features of CIC-NUTM1 Sarcomas, a New Molecular Variant of the Family of CIC-Fused Sarcomas. Le Loarer F, Pissaloux D, Watson S, Godfraind C, Galmiche-Rolland L, Silva K, Mayeur L, Italiano A, Michot A, Pierron G, Vasiljevic A, Ranchère-Vince D, Coindre JM, Tirode F. | 11/16/2019 |
Report subset of undifferentiated soft tissue and visceral tumors with NUTM1 gene fusions. | NUTM1 Gene Fusions Characterize a Subset of Undifferentiated Soft Tissue and Visceral Tumors. Dickson BC, Sung YS, Rosenblum MK, Reuter VE, Harb M, Wunder JS, Swanson D, Antonescu CR., Free PMC Article | 03/23/2019 |
Fluorescence in situ hybridization and targeted next-generation sequencing identified a CIC-NUTM1 fusion resulting from t(15;19)(q14;q13.2). In light of morphologic features that overlap with those of NC from typical anatomical sites we have seen previously, the tumor was best classified as falling within the NC spectrum rather than CIC-associated sarcoma. | CIC-NUTM1 fusion: A case which expands the spectrum of NUT-rearranged epithelioid malignancies. Schaefer IM, Dal Cin P, Landry LM, Fletcher CDM, Hanna GJ, French CA., Free PMC Article | 10/27/2018 |
Review and case series found that NUT midline carcinoma has dismal prognosis. Radiotherapy and chemotherapy improves survival, but do not provide long term control except in anecdotal cases. No impact on overall survival was found based on type of molecular translocation, i.e., NUT-BRD4, NUT-BRD3 or other variants. | Patterns of care and impact of prognostic factors in the outcome of NUT midline carcinoma: a systematic review and individual patient data analysis of 119 cases. Giridhar P, Mallick S, Kashyap L, Rath GK. | 07/21/2018 |
We postulate that BRD4-NUT (B4N) complexes override the preexisting histone code with new posttranslational modifications patterns that reflect aberrant transcription and that epigenetically modulate the nucleosome environment toward the NUT-midline carcinoma (NMC) state. | The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns. Zee BM, Dibona AB, Alekseyenko AA, French CA, Kuroda MI., Free PMC Article | 07/1/2017 |
we also identified a complex genomic rearrangement involving the BRD4-NUT rearrangement underlying the simple t(15;19) karyotype in Nuclear protein in testis (NUT) midline carcinoma | Complex chromosomal rearrangements by single catastrophic pathogenesis in NUT midline carcinoma. Lee JK, Louzada S, An Y, Kim SY, Kim S, Youk J, Park S, Koo SH, Keam B, Jeon YK, Ku JL, Yang F, Kim TM, Ju YS., Free PMC Article | 05/6/2017 |
The clinical, radiographic, and histopathologic features of NUT midline carcinoma are discussed, as well as its management options. | Orbital Involvement by NUT Midline Carcinoma. D'Souza JN, Notz G, Bogdasarian RN, Cognetti DM, Curry JM, Rosen MR, Tuluc M, Evans JJ, Bilyk JR. | 06/11/2016 |
NUT gene rearrangement does not seem to be relevant in primary pulmonary carcinomas or carcinoid tumours of the lung | NUT expression in primary lung tumours. Lund-Iversen M, Grøholt KK, Helland Å, Borgen E, Brustugun OT., Free PMC Article | 05/28/2016 |