| LncRNA ADAMTS9-AS1 inhibits the stemness of lung adenocarcinoma cells by regulating miR-5009-3p/NPNT axis. | LncRNA ADAMTS9-AS1 inhibits the stemness of lung adenocarcinoma cells by regulating miR-5009-3p/NPNT axis.
Wang P, Zhang Y, Lv X, Zhou J, Cang S, Song Y. | 05/25/2023 |
| Missense Variants in <i>GFRA1</i> and <i>NPNT</i> Are Associated with Congenital Anomalies of the Kidney and Urinary Tract. | Missense Variants in GFRA1 and NPNT Are Associated with Congenital Anomalies of the Kidney and Urinary Tract.
Al-Hamed MH, Sayer JA, Alsahan N, Edwards N, Ali W, Tulbah M, Imtiaz F., Free PMC Article | 11/12/2022 |
| A null founder variant in NPNT, encoding nephronectin, causes autosomal recessive renal agenesis. | A null founder variant in NPNT, encoding nephronectin, causes autosomal recessive renal agenesis.
Al-Hamed MH, Altuwaijri N, Alsahan N, Ali W, Abdulwahab F, Alzahrani F, Majrashi N, Alkuraya FS. | 06/18/2022 |
| Integrated analysis identified NPNT as a potential key regulator in tumor metastasis of hepatocellular carcinoma. | Integrated analysis identified NPNT as a potential key regulator in tumor metastasis of hepatocellular carcinoma.
Huang L, Guan S, Feng L, Wei J, Wu L. | 04/23/2022 |
| Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis. | Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis.
Müller-Deile J, Sopel N, Ohs A, Rose V, Gröner M, Wrede C, Hegermann J, Daniel C, Amann K, Zahner G, Schiffer M., Free PMC Article | 12/18/2021 |
| A Biallelic Frameshift Mutation in Nephronectin Causes Bilateral Renal Agenesis in Humans. | A Biallelic Frameshift Mutation in Nephronectin Causes Bilateral Renal Agenesis in Humans.
Dai L, Li J, Xie L, Wang W, Lu Y, Xie M, Huang J, Shen K, Yang H, Pei C, Zhao Y, Zhang W., Free PMC Article | 10/23/2021 |
| Nephronectin is a prognostic biomarker and promotes gastric cancer cell proliferation, migration and invasion. | Nephronectin is a prognostic biomarker and promotes gastric cancer cell proliferation, migration and invasion.
Mei D, Zhao B, Zhang J, Xu H, Huang B. | 10/16/2021 |
| Serum Npnt was found to be higher in silicosis patients compared to healthy volunteers and seems to play a role in the progression of fibrosis with other cytokines. [review] | Role of Nephronectin in Pathophysiology of Silicosis.
Lee S, Honda M, Yamamoto S, Kumagai-Takei N, Yoshitome K, Nishimura Y, Sada N, Kon S, Otsuki T., Free PMC Article | 11/9/2019 |
| Biopsies from patients with focal segmental glomerulosclerosis and membranous nephropathy had increased miR-378a-3p expression and reduced glomerular levels of NPNT. | Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases.
Müller-Deile J, Dannenberg J, Schroder P, Lin MH, Miner JH, Chen R, Bräsen JH, Thum T, Nyström J, Staggs LB, Haller H, Fiedler J, Lorenzen JM, Schiffer M., Free PMC Article | 05/26/2018 |
| Nephronectin (NPNT), a member of the epidermal growth factor (EGF) repeat superfamily proteins and a homologue of EGFL6, is expressed in osteoblasts. Intriguingly, the gene expression of NPNT is reduced in the bone of osteoporosis patients. | NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase.
Kuek V, Yang Z, Chim SM, Zhu S, Xu H, Chow ST, Tickner J, Rosen V, Erber W, Li X, Qin A, Qian Y, Xu J., Free PMC Article | 04/28/2018 |
| The expression of nephronectin was sufficient to discriminate DN from other kidney diseases with mesangial matrix expansion and nodular lesions. | Nephronectin expression in glomeruli of renal biopsy specimens from various kidney diseases: nephronectin is expressed in the mesangial matrix expansion of diabetic nephropathy.
Nakatani S, Ishimura E, Mori K, Fukumoto S, Yamano S, Wei M, Emoto M, Wanibuchi H, Inaba M. | 02/8/2014 |
| Nephronectin is associated with the development of diabetic glomerulosclerosis. | Proteome analysis of laser microdissected glomeruli from formalin-fixed paraffin-embedded kidneys of autopsies of diabetic patients: nephronectin is associated with the development of diabetic glomerulosclerosis.
Nakatani S, Wei M, Ishimura E, Kakehashi A, Mori K, Nishizawa Y, Inaba M, Wanibuchi H. | 12/8/2012 |
| Observational study of gene-disease association. (HuGE Navigator) | A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP., Free PMC Article | 06/30/2010 |
| MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7 | MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7.
Kahai S, Lee SC, Lee DY, Yang J, Li M, Wang CH, Jiang Z, Zhang Y, Peng C, Yang BB., Free PMC Article | 03/15/2010 |
| Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator) | Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter JI, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, Morrison AC, Enright PL, North KE, Heckbert SR, Lumley T, Stricker BH, O'Connor GT, London SJ., Free PMC Article | 01/20/2010 |