| Glucose transporter-2 regulation of VMN GABA neuron metabolic sensor and transmitter gene expression. | Glucose transporter-2 regulation of VMN GABA neuron metabolic sensor and transmitter gene expression.
Roy SC, Sapkota S, Pasula MB, Katakam S, Shrestha R, Briski KP., Free PMC Article | 07/9/2024 |
| NGF effects promote the maturation of rat pancreatic beta cells by regulating GLUT2 levels and distribution, and glucokinase activity. | NGF effects promote the maturation of rat pancreatic beta cells by regulating GLUT2 levels and distribution, and glucokinase activity.
Samario-Román J, Velasco M, Larqué C, Cárdenas-Vázquez R, Ortiz-Huidobro RI, Hiriart M., Free PMC Article | 06/28/2024 |
| HCV affects KATP channels through GnT-IVa-mediated N-glycosylation of GLUT2 on the surface of pancreatic beta-cells leading to impaired insulin secretion. | HCV affects K(ATP) channels through GnT-IVa-mediated N-glycosylation of GLUT2 on the surface of pancreatic β-cells leading to impaired insulin secretion.
Niu B, Ma L, Yao L, Zhang Y, Su H., Free PMC Article | 06/3/2024 |
| Sex Dimorphic Glucose Transporter-2 Regulation of Hypothalamic Astrocyte Glucose and Energy Sensor Expression and Glycogen Metabolism. | Sex Dimorphic Glucose Transporter-2 Regulation of Hypothalamic Astrocyte Glucose and Energy Sensor Expression and Glycogen Metabolism.
Pasula MB, Napit PR, Alhamyani A, Roy SC, Sylvester PW, Bheemanapally K, Briski KP., Free PMC Article | 02/11/2023 |
| Perinatal stress exposure induced oxidative stress, metabolism disorder, and reduced GLUT-2 in adult offspring of rats. | Perinatal stress exposure induced oxidative stress, metabolism disorder, and reduced GLUT-2 in adult offspring of rats.
Salimi M, Eskandari F, Khodagholi F, Abdollahifar MA, Hedayati M, Zardooz H, Keyhanmanesh R. | 12/10/2022 |
| Fructose-rich diet and walnut supplementation differently regulate rat hypothalamic and hippocampal glucose transporters expression. | Fructose-rich diet and walnut supplementation differently regulate rat hypothalamic and hippocampal glucose transporters expression.
Dakic T, Lakic I, Zec M, Takic M, Stojiljkovic M, Jevdjovic T. | 10/23/2021 |
| The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver. | The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver.
Kur P, Kolasa-Wołosiuk A, Grabowska M, Kram A, Tarnowski M, Baranowska-Bosiacka I, Rzeszotek S, Piasecka M, Wiszniewska B., Free PMC Article | 09/11/2021 |
| Piperlongumine attenuates oxidative stress, inflammatory, and apoptosis through modulating the GLUT-2/4 and AKT signaling pathway in streptozotocin-induced diabetic rats. | Piperlongumine attenuates oxidative stress, inflammatory, and apoptosis through modulating the GLUT-2/4 and AKT signaling pathway in streptozotocin-induced diabetic rats.
Xu P, Xiao J, Chi S. | 07/31/2021 |
| Glut2 and Glut4 regulate glucose transport during wound healing beneath the injured dental pulp area. This may contribute to the development of new vital pulp therapy for patients with deep caries | Glucose Transporter 2 and 4 Are Involved in Glucose Supply during Pulpal Wound Healing after Pulpotomy with Mineral Trioxide Aggregate in Rat Molars.
Tohma A, Ohkura N, Yoshiba K, Takeuchi R, Yoshiba N, Edanami N, Shirakashi M, Ibn Belal RS, Ohshima H, Noiri Y. | 02/1/2020 |
| activation of the p38MAPK alpha might be required for thyroid stimulating hormone-induced GLUT2 gene transcription in pancreatic beta cells. | Thyroid stimulating hormone stimulates the expression of glucose transporter 2 via its receptor in pancreatic β cell line, INS-1 cells.
Lyu J, Imachi H, Yoshimoto T, Fukunaga K, Sato S, Ibata T, Kobayashi T, Dong T, Yonezaki K, Yamaji N, Kikuchi F, Iwama H, Ishikawa R, Haba R, Sugiyama Y, Zhang H, Murao K., Free PMC Article | 12/22/2018 |
| GLUT2 inhibition in tanycytes disrupted the hypothalamic glucosensing mechanism that controls feeding behavior. Inhibition of GLUT2 expression resulted in increased food intake and a gain in body weight in rats. | Glial hypothalamic inhibition of GLUT2 expression alters satiety, impacting eating behavior.
Barahona MJ, Llanos P, Recabal A, Escobar-Acuña K, Elizondo-Vega R, Salgado M, Ordenes P, Uribe E, Sepúlveda FJ, Araneda RC, García-Robles MA., Free PMC Article | 08/25/2018 |
| A single low streptozotocin (STZ) dose into the lateral ventricles of the adult rats induces wide-spread neuroinflammation in the cortical, hippocampal and hypothalamic regions and more regional-specific alterations in GLUT2 and insulin receptor (IR) protein expression, observed as early as 1 h after the treatment. GLUT2 and IR expression was altered in areas close to the site of STZ release and downstream the CSF flow. | Rat brain glucose transporter-2, insulin receptor and glial expression are acute targets of intracerebroventricular streptozotocin: risk factors for sporadic Alzheimer's disease?
Knezovic A, Loncar A, Homolak J, Smailovic U, Osmanovic Barilar J, Ganoci L, Bozina N, Riederer P, Salkovic-Petrisic M. | 03/24/2018 |
| High-fat diet alone or combined with foot-shock, predispose female rats to impaired insulin secretion, at least in part, by interfering with estradiol levels in the proestrus phase and decreasing pancreatic GLUT2 protein levels. | High-fat diet with stress impaired islets' insulin secretion by reducing plasma estradiol and pancreatic GLUT2 protein levels in rats' proestrus phase.
Salimi M, Zardooz H, Khodagholi F, Rostamkhani F, Shaerzadeh F. | 05/27/2017 |
| Suggest p-coumaric aicd modulates glucose and lipid metabolism via GLUT 2 activation in the pancreatic and has potentially beneficial effects in improving or treating metabolic disorders. | Antidiabetic and antihyperlipidemic activity of p-coumaric acid in diabetic rats, role of pancreatic GLUT 2: In vivo approach.
Amalan V, Vijayakumar N, Indumathi D, Ramakrishnan A. | 02/18/2017 |
| Data suggest that down-regulation of expression of GLUT2 in liver (which is up-regulated by high-fructose diet) decreases insulin resistance and thus may prevent glucose intolerance and non-alcoholic fatty liver disease; here, expression of GLUT2 in liver was down-regulated by a dietary factor, supplemental beta-hydroxy-beta-methylbutyrate. | The ergogenic supplement β-hydroxy-β-methylbutyrate (HMB) attenuates insulin resistance through suppressing GLUT-2 in rat liver.
Sharawy MH, El-Awady MS, Megahed N, Gameil NM. | 02/18/2017 |
| Attenuation of insulin resistance in rats by agmatine: role of SREBP-1c, mTOR and GLUT-2 | Attenuation of insulin resistance in rats by agmatine: role of SREBP-1c, mTOR and GLUT-2.
Sharawy MH, El-Awady MS, Megahed N, Gameil NM. | 10/8/2016 |
| Ferulic acid reduced hepatic GLUT2 expression in diabetic animals by impairing the interaction between transcription factors SREBP1c, HNF1alpha and HNF3beta and GLUT2 gene promoter. | Ferulic acid regulates hepatic GLUT2 gene expression in high fat and fructose-induced type-2 diabetic adult male rat.
Narasimhan A, Chinnaiyan M, Karundevi B. | 05/21/2016 |
| glucose stimulates neurotensin secretion by uptake through SGLT1 and GLUT2, both causing depolarization either as a consequence of sodium-coupled uptake (SGLT1) or by closure of KATP channels (GLUT2 and SGLT1) secondary to the ATP-generating metabolism of glucose. | Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2, leading to cell depolarization and calcium influx.
Kuhre RE, Bechmann LE, Wewer Albrechtsen NJ, Hartmann B, Holst JJ. | 08/29/2015 |
| Enzyme of the de novo purine synthesis pathway(ATIC)and the putative tyrosine phosphatase PTPLAD1 regulate Glut2(SLC2A2)translocation in HEK293 cells. SiRNA-mediated knockdown of ATIC delayed insulin response of Glut2 translocation while depletion of PTPLAD1(HACD3}enhanced it in HEK293 cells.AICAR stimulation affect Glut2 endocytosis in Golgi/endosomes under insulin stimulation and its translocation in HEK293 cells. | The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network.
Boutchueng-Djidjou M, Collard-Simard G, Fortier S, Hébert SS, Kelly I, Landry CR, Faure RL., Free PMC Article | 08/18/2015 |
| Nuclear translocation of Akt2 and synthesis of GLUT2 is increased in the hepatocytes of chard or/and insulin-treated hyperglycemic rats. | Chard (Beta vulgaris L. var. cicla) extract ameliorates hyperglycemia by increasing GLUT2 through Akt2 and antioxidant defense in the liver of rats.
Gezginci-Oktayoglu S, Sacan O, Bolkent S, Ipci Y, Kabasakal L, Sener G, Yanardag R. | 05/16/2015 |
| SGLT1 or GLUT2 interact with the cytoskeleton in the intestinal epithelium during hexose absorption. | [The interaction between SGLT1 or GLUT2 glucose transporter and the cytoskeleton in the enterocyte as well as Caco2 cell during hexose absorption].
Grefner NM, Gromova LV, Gruzdkov AA, Komissarchik IaIu. | 03/21/2015 |
| The aim of the work was to evaluate GLUT1 and GLUT2 in kidneys of an animal model of metabolic syndrome. | Changes in renal glucose transporters in an animal model of metabolic syndrome.
Lehnen AM, Leguisamo NM, Dias LD, Pinto GH, Okamoto NM, Machado UF, Schaan BD. | 06/7/2014 |
| HNF-1alpha, HNF-4alpha and FOXA2 transcriptional factors are involved in diabetes-induced overexpression of Slc2a2 gene in the liver and kidney. | Hepatocyte nuclear factors 1α/4α and forkhead box A2 regulate the solute carrier 2A2 (Slc2a2) gene expression in the liver and kidney of diabetic rats.
David-Silva A, Freitas HS, Okamoto MM, Sabino-Silva R, Schaan BD, Machado UF. | 12/28/2013 |
| Intestinal dehydroascorbic acid (DHA) transport is mediated by the facilitative sugar transporters, GLUT2 and GLUT8 | Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8.
Corpe CP, Eck P, Wang J, Al-Hasani H, Levine M., Free PMC Article | 06/1/2013 |
| A small amount of GLUT2 is active at the lesser luminal concentrations of glucose, but when exposed to concentrations of 100 mM, the enterocyte presumably changes its phenotype by recruiting GLUT2 apically to markedly augment glucose absorption. | Acute enterocyte adaptation to luminal glucose: a posttranslational mechanism for rapid apical recruitment of the transporter GLUT2.
Chaudhry RM, Scow JS, Madhavan S, Duenes JA, Sarr MG., Free PMC Article | 08/18/2012 |