RICTOR/mTORC2 downregulation in BRAF(V600E) melanoma cells promotes resistance to BRAF/MEK inhibition.
Ponzone L, Audrito V, Landi C, Moiso E, Levra Levron C, Ferrua S, Savino A, Vitale N, Gasparrini M, Avalle L, Vantaggiato L, Shaba E, Tassone B, Saoncella S, Orso F, Viavattene D, Marina E, Fiorilla I, Burrone G, Abili Y, Altruda F, Bini L, Deaglio S, Defilippi P, Menga A, Poli V, Porporato PE, Provero P, Raffaelli N, Riganti C, Taverna D, Cavallo F, Calautti E., Free PMC Article

KLF4 Suppresses the Progression of Hepatocellular Carcinoma by Reducing Tumor ATP Synthesis through Targeting the Mir-206/RICTOR Axis.
Wang Y, Zuo D, Huang Z, Qiu Y, Wu Z, Liu S, Zeng Y, Qiu Z, He W, Li B, Yuan Y, Niu Y, Qiu J., Free PMC Article

RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.
Wang C, Chen Z, Yi Y, Ding Y, Xu F, Kang H, Lin K, Shu X, Zhong Z, Zhang Z, Liu J, Xu Z, Liu L, He X, Chang Y, Zhao Q.

Rictor mediates p53 deactivation to facilitate the malignant transformation of hepatocytes and promote hepatocarcinogenesis.
Wang C, Kang H, Yi Y, Ding Y, Wang F, Luo J, Ye M, Hong Y, Xia C, Yan J, Liu L, Liu J, Zhong Z, Zhang Z, Zhao Q, Chang Y., Free PMC Article

Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing.
Sztankovics D, Krencz I, Moldvai D, Dankó T, Nagy Á, Nagy N, Bedics G, Rókusz A, Papp G, Tőkés AM, Pápay J, Sápi Z, Dezső K, Bödör C, Sebestyén A., Free PMC Article

UBXN2A suppresses the Rictor-mTORC2 signaling pathway, an established tumorigenic pathway in human colorectal cancer.
Sane S, Srinivasan R, Potts RA, Eikanger M, Zagirova D, Freeling J, Reihe CA, Antony RM, Gupta BK, Lynch D, Bleeker J, Turaihi H, Pillatzki A, Zhou W, Luo X, Linnebacher M, Agany D, Zohim EG, Humphrey LE, Black AR, Rezvani K., Free PMC Article

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.
Luciano AK, Korobkina ED, Lyons SP, Haley JA, Fluharty SM, Jung SM, Kettenbach AN, Guertin DA., Free PMC Article

Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt.
Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D., Free PMC Article

Epithelial-mesenchymal reprogramming by KLF4-regulated Rictor expression contributes to metastasis of non-small cell lung cancer cells.
Zhou H, Guan Q, Hou X, Liu L, Zhou L, Li W, Liu H., Free PMC Article

LncRNA KCNQ1OT1 promotes osteogenic differentiation via miR-205-5p/RICTOR axis.
Yang JJ, Peng WX, Zhang MB.

Rictor promotes cell migration and actin polymerization through regulating ABLIM1 phosphorylation in Hepatocellular Carcinoma.
Dong X, Feng M, Yang H, Liu H, Guo H, Gao X, Liu Y, Liu R, Zhang N, Chen R, Kong R., Free PMC Article

An RNA-RNA crosstalk network involving HMGB1 and RICTOR facilitates hepatocellular carcinoma tumorigenesis by promoting glutamine metabolism and impedes immunotherapy by PD-L1+ exosomes activity.
Wei Y, Tang X, Ren Y, Yang Y, Song F, Fu J, Liu S, Yu M, Chen J, Wang S, Zhang K, Tan Y, Han Z, Wei L, Zhang B, Cheng Z, Li L, Wang H., Free PMC Article

Rictor, an essential component of mTOR complex 2, undergoes caspase-mediated cleavage during apoptosis induced by multiple stimuli.
Zhao L, Zhu L, Oh YT, Qian G, Chen Z, Sun SY.

TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2.
Guo Z, Zhang X, Zhu H, Zhong N, Luo X, Zhang Y, Tu F, Zhong J, Wang X, He J, Huang L., Free PMC Article

RICTOR Amplification Promotes NSCLC Cell Proliferation through Formation and Activation of mTORC2 at the Expense of mTORC1.
Kim LC, Rhee CH, Chen J., Free PMC Article

Different Role of Raptor and Rictor in Regulating Rasfonin-Induced Autophagy and Apoptosis in Renal Carcinoma Cells.
Hou B, Liu S, Li E, Jiang X.

The role of RICTOR amplification in targeted therapy and drug resistance.
Zhao D, Jiang M, Zhang X, Hou H., Free PMC Article

Raptor and rictor expression in patients with human papillomavirus-related oropharyngeal squamous cell carcinoma.
Kondo S, Hirakawa H, Ikegami T, Uehara T, Agena S, Uezato J, Kinjyo H, Kise N, Yamashita Y, Tanaka K, Hasegawa N, Kiyuna A, Maeda H, Suzuki M, Gahana A., Free PMC Article

Rictor promotes tumor progression of rapamycin-insensitive triple-negative breast cancer cells.
Watanabe R, Miyata M, Oneyama C.

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.
Wong CK, Lambert AW, Ozturk S, Papageorgis P, Lopez D, Shen N, Sen Z, Abdolmaleky HM, Győrffy B, Feng H, Thiagalingam S., Free PMC Article

LncRNA FOXD3-AS1 Mediates AKT Pathway to Promote Growth and Invasion in Hepatocellular Carcinoma Through Regulating RICTOR.
Liu C, Zhang M, Zhao J, Zhu X, Zhu L, Yan M, Zhang X, Zhang R.

Correlation between RICTOR overexpression and amplification in advanced solid tumors.
Bang H, Ahn S, Ji Kim E, Kim ST, Park HY, Lee J, Kim KM.

MiR-155 aggravates impaired autophagy of pancreatic acinar cells through targeting Rictor.
Zhang X, Chu J, Sun H, Zhao D, Ma B, Xue D, Zhang W, Li Z.

Expression of Raptor and Rictor and their relationships with angiogenesis in colorectal cancer.
Wen FF, Li XY, Li YY, He S, Xu XY, Liu YH, Liu L, Wu SH.

PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers.
Beck C, Rodriguez-Vargas JM, Boehler C, Robert I, Heyer V, Hanini N, Gauthier LR, Tissier A, Schreiber V, Elofsson M, Reina San Martin B, Dantzer F., Free PMC Article