| Gastrin: a new branch of the gastropancreatic axis that can explain the effect of sleeve gastrectomy on glucose metabolism. | Gastrin: a new branch of the gastropancreatic axis that can explain the effect of sleeve gastrectomy on glucose metabolism.
Pérez-Arana GM, Almorza-Gomar D, Mayo-Ossorio MA, Ramírez AC, Castro-Santiago MJ, Valverde-Martínez A, Casado-Maestre MD, Visiedo F, Bohórquez-Sierra JC, Prada-Oliveira JA. | 04/12/2024 |
| we examined the chronic effects of a GLP-1-gastrin dual agonist ZP3022 on glycemic control and beta cell dysfunction in overtly diabetic Zucker Diabetic Fatty | The anti-diabetic effects of GLP-1-gastrin dual agonist ZP3022 in ZDF rats.
Skarbaliene J, Secher T, Jelsing J, Ansarullah, Neerup TS, Billestrup N, Fosgerau K. | 03/5/2016 |
| treatment with gastrin, a CCK2R agonist, stimulated the secretion of GLP-1, and that this effect was likely due to increased expression of proglucagon and PCSK1 (also known as prohormone convertase 3 (PC3 gene)). | Expression of cholecystokinin2-receptor in rat and human L cells and the stimulation of glucagon-like peptide-1 secretion by gastrin treatment.
Cao Y, Cao X, Liu XM. | 11/21/2015 |
| The results suggested that clusterin may contribute to gastrin's growth-promoting effect on the oxyntic mucosa. | Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats.
Fjeldbo CS, Bakke I, Erlandsen SE, Holmseth J, Lægreid A, Sandvik AK, Thommesen L, Bruland T. | 02/18/2012 |
| G cells are luminal sampling chemomechanosensory cells whose gastrin secretion is regulated by neural, hormonal, luminal, and mechanical factors through protein kinase A activation, cAMP signaling, and mitogen-activated protein kinase phosphorylation. | Delineation of the chemomechanosensory regulation of gastrin secretion using pure rodent G cells.
Kidd M, Hauso Ø, Drozdov I, Gustafsson BI, Modlin IM. | 01/21/2010 |
| the role of JAK-dependent pathways in the regulation of E-cadherin-dependent cell-cell adhesion by gastrin | Involvement of JAK2 upstream of the PI 3-kinase in cell-cell adhesion regulation by gastrin.
Ferrand A, Kowalski-Chauvel A, Bertrand C, Pradayrol L, Fourmy D, Dufresne M, Seva C. | 01/21/2010 |
| role in increasing expression of COX-2 mRNA and protein, the activity of the COX-2 promoter, and the release of prostaglandin E(2) | Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor.
Guo YS, Cheng JZ, Jin GF, Gutkind JS, Hellmich MR, Townsend CM Jr. | 01/21/2010 |
| gastrin induces Akt through activation of CCKB receptors and of intracellular calcium-dependent, PKC-independent, pathways | Intracellular mechanisms mediating the anti-apoptotic action of gastrin.
Ramamoorthy S, Stepan V, Todisco A. | 01/21/2010 |
| GIP, GLP-1, insulin and gastrin have roles in ghrelin release in the isolated rat stomach | Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach.
Lippl F, Kircher F, Erdmann J, Allescher HD, Schusdziarra V. | 01/21/2010 |
| plays a role in the development of gastric mucosa, ECL cells and A-like cells in newborn and young rats | Role of gastrin in the development of gastric mucosa, ECL cells and A-like cells in newborn and young rats.
Björkqvist M, Dornonville de la Cour C, Zhao CM, Gagnemo-Persson R, Håkanson R, Norlén P. | 01/21/2010 |
| High temperature can affect gastrin, somatostatin and motilin production in the gastric antral mucosa of rats with gastric ulcer. | Effect of high temperature on gastrin, somatostatin and motilin production in ulcerous gastric antral mucosa of rats.
Sun FP, Dan HL, Song YG, Cheng W. | 01/21/2010 |
| gastrin- and PACAP-stimulated secretion of histamine and pancreastatin is inhibited by somatostatin, misoprostol and galanin in enterochromaffin-like cells | Somatostatin, misoprostol and galanin inhibit gastrin- and PACAP-stimulated secretion of histamine and pancreastatin from ECL cells by blocking specific Ca2+ channels.
Björkqvist M, Bernsand M, Eliasson L, Håkanson R, Lindström E. | 01/21/2010 |
| hypogastrinemia and impaired enterochromaffin cell function in the oxyntic mucosa of the stomach might be partially responsible for the reduction in body weight that occurs after gastric bypass | Is gastrin partially responsible for body weight reduction after gastric bypass?
Stenstrom B, Zhao CM, Tømmerås K, Arum CJ, Chen D. | 01/21/2010 |
| study demonstrates that gastrin enhances gastric mucosal integrity through cyclooxygenase-2 | Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats.
Komori M, Tsuji S, Sun WH, Tsujii M, Kawai N, Yasumaru M, Kakiuchi Y, Kimura A, Sasaki Y, Higashiyama S, Kawano S, Hori M. | 01/21/2010 |
| Data suggest that distention of isolated rat stomach stimulates somatostatin release via cholinergic and non-cholinergic TTX-insensitive pathways, and that these pathways are responsible for distention-induced inhibition of gastrin release. | Mechanisms for regulation of gastrin and somatostatin release from isolated rat stomach during gastric distention.
Li YY., Free PMC Article | 01/21/2010 |