| Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier. | Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier.
Shen S, Nan W, Zhang W, Wu H, Zhang Y. | 10/17/2024 |
| Bone Morphogenetic Protein-4 Promotes Phenotypic Modulation via SMAD-4/MCT-4 Axis in Vascular Smooth Muscle Cells. | Bone Morphogenetic Protein-4 Promotes Phenotypic Modulation via SMAD-4/MCT-4 Axis in Vascular Smooth Muscle Cells.
Li Q, Li Z, Li J, Qin X, Wu F, Chen C. | 10/7/2024 |
| Regulation of Shh/Bmp4 Signaling Pathway by DNA Methylation in Rectal Nervous System Development of Fetal Rats with Anorectal Malformation. | Regulation of Shh/Bmp4 Signaling Pathway by DNA Methylation in Rectal Nervous System Development of Fetal Rats with Anorectal Malformation.
Zhou Y, Yang Y, Dong R, Huang Y. | 06/23/2023 |
| Hypermethylation of the Bmp4 promoter dampens binding of HIF-1alpha and impairs its cardiac protective effects from oxidative stress in prenatally GC-exposed offspring. | Hypermethylation of the Bmp4 promoter dampens binding of HIF-1α and impairs its cardiac protective effects from oxidative stress in prenatally GC-exposed offspring.
Gao LT, Yuan JQ, Zhang ZY, Zhao HM, Gao L., Free PMC Article | 02/28/2023 |
| BMP-4 impedes endothelial cell migration in neointimal hyperplasia via FoXO-3 specific modulation of reactive oxygen species. | BMP-4 impedes endothelial cell migration in neointimal hyperplasia via FoXO-3 specific modulation of reactive oxygen species.
Li Q, Kou X, Qin X, Li Z, Li J, Chen C. | 07/2/2022 |
| Secreted key regulators (Fgf1, Bmp4, Gdf3) are expressed by PAC1-immunopositive retinal ganglion cells in the postnatal rat retina. | Secreted key regulators (Fgf1, Bmp4, Gdf3) are expressed by PAC1-immunopositive retinal ganglion cells in the postnatal rat retina.
Dénes V, Kovacs K, Lukáts Á, Mester A, Berta G, Szabó A, Gabriel R., Free PMC Article | 05/14/2022 |
| Bone morphogenetic proteins in biomineralization of two endodontic restorative cements. | Bone morphogenetic proteins in biomineralization of two endodontic restorative cements.
Souza TA, Bezerra MM, Silva PGB, Costa JJN, Carneiro RFLA, Barcelos JOF, Vasconcelos BC, Chaves HV. | 01/22/2022 |
| The role of bone morphogenetic protein 4 in corneal injury repair. | The role of bone morphogenetic protein 4 in corneal injury repair.
Hu H, Wang S, He Y, Shen S, Yao B, Xu D, Liu X, Zhang Y. | 12/18/2021 |
| Stimulation of Epithelial Sodium Channels in Endothelial Cells by Bone Morphogenetic Protein-4 Contributes to Salt-Sensitive Hypertension in Rats. | Stimulation of Epithelial Sodium Channels in Endothelial Cells by Bone Morphogenetic Protein-4 Contributes to Salt-Sensitive Hypertension in Rats.
Yang X, Niu N, Liang C, Wu MM, Tang LL, Wang QS, Lou J, Song BL, Zheng WW, Ma HP, Zhang ZR., Free PMC Article | 05/22/2021 |
| Acute upregulation of bone morphogenetic protein-4 regulates endogenous cell response and promotes cell death in spinal cord injury. | Acute upregulation of bone morphogenetic protein-4 regulates endogenous cell response and promotes cell death in spinal cord injury.
Hart CG, Dyck SM, Kataria H, Alizadeh A, Nagakannan P, Thliveris JA, Eftekharpour E, Karimi-Abdolrezaee S. | 10/24/2020 |
| reductions in BMP4 expression were possibly responsible for dysfunction of the lumbosacral spinal cord during late developmental stages in anorectal malformations fetal rats | Bone morphogenetic protein 4 expression in the developing lumbosacral spinal cord of rat embryos with anorectal malformations.
Yang Z, Jia H, Bai Y, Wang W. | 12/22/2018 |
| elevated serum BMP-2 and BMP-4 levels may serve as serum markers for chronic kidney disease vascular calcification. | Bone Morphogenetic Proteins 2/4 Are Upregulated during the Early Development of Vascular Calcification in Chronic Kidney Disease.
Wei X, Wu W, Li L, Lin J, Liu Q, Gan L, Ou S., Free PMC Article | 10/6/2018 |
| beta-Catenin siRNA reduces Ngnl1 and increases BMP4 mRNA expression levels in rat neural stem cells. | Impact of siRNA targeting of β-catenin on differentiation of rat neural stem cells and gene expression of Ngn1 and BMP4 following in vitro hypoxic-ischemic brain damage.
Zhang X, Zhu C, Luo Q, Dong J, Liu L, Li M, Zhu H, Ma X, Wang J., Free PMC Article | 04/15/2017 |
| Art is able to improve the renal function decline and renal fibrosis induced by UUO, which may be associated with the up-regulation of BMP-7 and down-regulation of USAG-1. | Artesunate attenuates unilateral ureteral obstruction-induced renal fibrosis by regulating the expressions of bone morphogenetic protein-7 and uterine sensitization-associated gene-1 in rats.
Cao J, Wang W, Li Y, Xia J, Peng Y, Zhang Y, Xia A. | 01/14/2017 |
| Data suggest that the bone morphogenetic protein (BMP) signaling pathway may be a key regulatory point in neurotrophin-3 (NT-3) transfected neuronal differentiation of mesenchymal stem cells (MSCs). | Neurotrophine-3 may contribute to neuronal differentiation of mesenchymal stem cells through the activation of the bone morphogenetic protein pathway.
Li L, Li Y, Jiang H. | 04/30/2016 |
| calbindin1 in rat primary islet cells reduced glucose-stimulated insulin secretion (GSIS), and the effect of BMP4 on GSIS was lost in islets from calbindin1 (Calb1) knockout mice | Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents.
Christensen GL, Jacobsen ML, Wendt A, Mollet IG, Friberg J, Frederiksen KS, Meyer M, Bruun C, Eliasson L, Billestrup N. | 03/12/2016 |
| In the presence of BMP4, the inner ear genes NF-M, Neurog1, GluR4, NeuroD, Calretinin, NeuN, Tau, and GATA3 were up-regulated in mesenchymal stromal cells. | BMP4: a Possible Key Factor in Differentiation of Auditory Neuron-Like Cells from Bone-Derived Mesenchymal Stromal Cells.
Peng T, Zhu G, Dong Y, Zeng J, Li W, Guo W, Chen Y, Duan M, Hocher B, Xie D. | 12/19/2015 |
| The endothelial markers co-localized with the enhanced BMP4 expression, suggesting that vascular cells play a role BMP4 induction. | Effect of Diabetes Mellitus on Adipocyte-Derived Stem Cells in Rat.
Jumabay M, Moon JH, Yeerna H, Boström KI., Free PMC Article | 10/17/2015 |
| BMP-4 promoted protein carbonylation, which was followed by decarbonylation or degradation in primary rat aortic endothelial cells. | Bone morphogenic protein-4-induced oxidant signaling via protein carbonylation for endothelial dysfunction.
Wong CM, Zhang Y, Huang Y. | 06/20/2015 |
| BMP4 may affect the expression of NR2B, thus playing a role in regulating the survival of cochlear epithelial cells. | NMDA receptors are involved in the regulation of BMP4-mediated survival in rat cochlear epithelial cells.
Chen J, Zheng Y, Xiong H, Ou Y. | 11/22/2014 |
| BMP2 antagonizes BMP4-induced cardiomyocyte hypertrophy and apoptosis. The anti-apoptotic effects of BMP2 on BMP4-induced cardiomyocyte apoptosis might be through activating Akt and inhibiting JNK activation. | Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis.
Lu J, Sun B, Huo R, Wang YC, Yang D, Xing Y, Xiao XL, Xie X, Dong DL. | 09/6/2014 |
| The current study indicates that CHRDL1 protein antagonizes BMP4 activity and induces spinal cordderived NSCs to differentiate into neurons. | Chordin-like protein 1 promotes neuronal differentiation by inhibiting bone morphogenetic protein-4 in neural stem cells.
Gao WL, Zhang SQ, Zhang H, Wan B, Yin ZS. | 07/26/2014 |
| conclude that BMP4 contributes to the downregulation of Kv4.3 K(+) channels in pathological cardiac hypertrophy and the underlying mechanism might be through increasing ROS production | Bone morphogenetic protein-4 contributes to the down-regulation of Kv4.3 K+ channels in pathological cardiac hypertrophy.
Sun B, Sheng Y, Huo R, Hu CW, Lu J, Li SL, Liu X, Wang YC, Dong DL. | 10/26/2013 |
| BMP4 participates in the regulation of Ca(2+) signaling in PASMCs by modulating TRPC channel expression via activating p38 and ERK1/2 MAPK pathways. | BMP4 increases canonical transient receptor potential protein expression by activating p38 MAPK and ERK1/2 signaling pathways in pulmonary arterial smooth muscle cells.
Li X, Lu W, Fu X, Zhang Y, Yang K, Zhong N, Ran P, Wang J., Free PMC Article | 10/19/2013 |
| These data suggest that BMP4 may regulate survival through the Id1/EGFR pathway during development of the rat inner ear. | Bone morphogenetic protein 4, inhibitor of differentiation 1, and epidermal growth factor receptor regulate the survival of cochlear sensory epithelial cells.
Chen J, Sun W, Zheng Y, Xiong H, Cai Y. | 08/10/2013 |