| Identification of two novel FUT1 mutations in people with Bombay phenotype from Iran. | Identification of two novel FUT1 mutations in people with Bombay phenotype from Iran.
Shahriyari F, Oodi A, Kenari FN, Shahabi M. | 06/9/2023 |
| FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis. | FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis.
Luo J, Mao K, Zhu Z, Ye J, Li L, Wang D, Zhou J, Lin F, Li J, Ye J., Free PMC Article | 04/26/2023 |
| Molecular Genetic Analysis of Para-Bombay Phenotype in Chinese: Identification of a Novel FUT1 Allele. | Molecular Genetic Analysis of Para-Bombay Phenotype in Chinese: Identification of a Novel FUT1 Allele.
Li T, Shan Y, Zhou X, Wu L, Xie J, Du C, Chong J, Liu J. | 01/21/2023 |
| Two novel alleles on Fucosyltransferase 2 from northern Thai para-Bombay family and computational prediction on mutation effect. | Two novel alleles on Fucosyltransferase 2 from northern Thai para-Bombay family and computational prediction on mutation effect.
Anukul N, Wita R, Leetrakool N, Sirikul C, Veeraphan N, Wongchai S. | 04/23/2022 |
| [Analysis of two novel variants of FUT1 gene in a Chinese family with para-Bombay phenotype]. | [Analysis of two novel variants of FUT1 gene in a Chinese family with para-Bombay phenotype].
Zhang K, Lin F, Li X, Zhang X, Li J. | 10/16/2021 |
| Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma. | Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma.
Loong JH, Wong TL, Tong M, Sharma R, Zhou L, Ng KY, Yu HJ, Li CH, Man K, Lo CM, Guan XY, Lee TK, Yun JP, Ma SK., Free PMC Article | 10/9/2021 |
| miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11. | miR-5193, regulated by FUT1, suppresses proliferation and migration of ovarian cancer cells by targeting TRIM11.
Song Z, Guo Q, Wang H, Gao L, Wang S, Liu D, Liu J, Qi Y, Lin B. | 08/28/2021 |
| [Serological Identification and FUT1 Gene Mutation Analysis of 8 Individuals with Para-Bombay Phenotypes in Guangxi]. | [Serological Identification and FUT1 Gene Mutation Analysis of 8 Individuals with Para-Bombay Phenotypes in Guangxi].
Liu JL, Liu XJ, Ma TT, Chen JR, Li LL. | 08/14/2021 |
| Two novel FUT1 alleles that cause para-Bombay phenotype in a Chinese individual. | Two novel FUT1 alleles that cause para-Bombay phenotype in a Chinese individual.
Lin FQ, Zhang KL, Li XF, Zhang X, Liu Y, Li JP. | 07/3/2021 |
| [Serological and molecular biological analysis of an individual with para-Bombay blood group due to homozygous c.948C>A variant of FUT1 gene]. | [Serological and molecular biological analysis of an individual with para-Bombay blood group due to homozygous c.948C>A variant of FUT1 gene].
Ma C, Luo Y, Yang X, Yu Y, Wang D. | 05/22/2021 |
| ADPGK-AS1 promotes the progression of colorectal cancer via sponging miR-525 to upregulate FUT1. | ADPGK-AS1 promotes the progression of colorectal cancer via sponging miR-525 to upregulate FUT1.
Jiang HY, Wang ZJ. | 03/20/2021 |
| In patients with hepatocellular carcinoma, Kaplan Meier survival analysis showed significantly shorter relapse-free survival for those with high expression of FUT1. | High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma.
Kuo HH, Lin RJ, Hung JT, Hsieh CB, Hung TH, Lo FY, Ho MY, Yeh CT, Huang YL, Yu J, Yu AL., Free PMC Article | 07/20/2019 |
| FUT1 promotes Taxol resistance of ovarian carcinoma through apoptosis-related proteins | Alpha1,2-fucosyl transferase gene, the key enzyme of Lewis y synthesis, promotes Taxol resistance of ovarian carcinoma through apoptosis-related proteins.
Li FF, Sha D, Qin XY, Li CZ, Lin B. | 07/6/2019 |
| The expression of FUT1, an alpha-1,2 fucosyltransferase, is remarkably down-regulated during melanoma progression, and the ectopic expression of FUT1 is sufficient to inhibit invadopodium formation and ECM degradation. | The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells.
Keeley T, Lin S, Lester DK, Lau EK, Yang S., Free PMC Article | 12/29/2018 |
| FUT1 mutations responsible for the H-deficient phenotype in the Polish population, including the first example of an abolished start codon. | FUT1 mutations responsible for the H-deficient phenotype in the Polish population, including the first example of an abolished start codon.
Michalewska B, Olsson ML, Naremska G, Walenciak J, Hult AK, Ozog A, Guz K, Brojer E, Storry JR., Free PMC Article | 12/22/2018 |
| The overexpression of miR-140-5p/149 inhibited apoptosis and promoted proliferation and autophagy of human primary chondrocytes via downregulating FUT1. | miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis.
Wang Z, Hu J, Pan Y, Shan Y, Jiang L, Qi X, Jia L. | 10/13/2018 |
| Results show that c-Fos binding to TPA response element of FUT1 promoter enhances the activation of FUT1 transcription by c-Jun. | c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer.
Hao Y, Zhu L, Yan L, Liu J, Liu D, Gao N, Tan M, Gao S, Lin B., Free PMC Article | 07/28/2018 |
| miR-339-5p downregulation contributes to Taxol resistance in small-cell lung cancer by targeting FUT1. | miR-339-5p downregulation contributes to Taxol resistance in small-cell lung cancer by targeting α1,2-fucosyltransferase 1.
Gan CZ, Li G, Luo QS, Li HM. | 06/16/2018 |
| High FUT1 expression is associated with breast cancer. | Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin).
Breiman A, López Robles MD, de Carné Trécesson S, Echasserieau K, Bernardeau K, Drickamer K, Imberty A, Barillé-Nion S, Altare F, Le Pendu J., Free PMC Article | 12/16/2017 |
| downregulation of FUT1, which leads to the perinuclear localization of LAMP-1 and 2, is correlated with increased rate of autophagic flux by decreasing mTOR signaling and increasing autolysosome formation. | Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells.
Tan KP, Ho MY, Cho HC, Yu J, Hung JT, Yu AL., Free PMC Article | 09/30/2017 |
| The H blood group system is defined by a terminal fucose residue found on red blood cells and in secretions formed by the action of alpha-1,2-fucosyltransferases 1 (alpha2FucT1) and 2 (alpha2FucT2), respectively. Mutant alleles of the corresponding FUT1 and FUT2 genes result in either a H- phenotype (Bombay phenotype) or a weak H phenotype (para-Bombay). Review. | The H blood group system.
Scharberg EA, Olsen C, Bugert P. | 07/22/2017 |
| Two novel FUT1 mutations have been identified in the proband's FUT1 gene. The insertion mutation in the FUT1 that caused a shift of the open reading frame and formed a termination codon early at Amino Acid Position 334 may be the main reason for H deficiency in this case. | Identification of a novel FUT1 allele with two mutations in a Chinese para-Bombay individual.
Wang L, Huang C, Wei Z, Tan J, Qin L, Tian L. | 06/24/2017 |
| Protein O-fucosyltransferase 1 promotes trophoblast cell proliferation by activating MAPK and PI3K/Akt signaling pathways.[poFUT1] | Protein O-fucosyltransferase 1 promotes trophoblast cell proliferation through activation of MAPK and PI3K/Akt signaling pathways.
Liu C, Liang X, Wang J, Zheng Q, Zhao Y, Khan MN, Liu S, Yan Q. | 04/1/2017 |
| Data suggest that the identification of genes in response to alpha1,2-fucosyl transferase (FUT1) may provide a theoretical basis for the investigations of the molecular mechanism of ovarian cancer. | Gene expression profile analysis in response to α1,2-fucosyl transferase (FUT1) gene transfection in epithelial ovarian carcinoma cells.
Gao S, Zhu L, Feng H, Hu Z, Jin S, Song Z, Liu D, Liu J, Hao Y, Li X, Lin B. | 02/25/2017 |
| alpha(1,2)-fucosyltransferase activity is involved in the development of multidrug resistance of chronic myeloid leukemia cells probably through FUT1 regulated the activity of EGFR/MAPK signaling pathway and the expression of P-gp. | Critical involvement of the α(1,2)-fucosyltransferase in multidrug resistance of human chronic myeloid leukemia.
Che Y, Ren X, Xu L, Ding X, Zhang X, Sun X. | 12/31/2016 |