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    Odc1 ornithine decarboxylase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24609, updated on 17-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The results indicated that overexpression of ODC gene promotes the proliferation while suppressing apoptosis of fibroblast-like synoviocytes in rats with rheumatoid arthritis.

    Effects of lentivirus-mediated ornithine decarboxylase gene on the proliferation and apoptosis of fibroblast-like synoviocytes in rats with arthritis.
    Liu W, Wu YH, Zhang L, Liu XY, Wang Y, Xue B, Liu B, Cai Y, Zhang B, Ji Y.

    02/17/2018
    These results suggest that IPC upregulates the Ornithine decarboxylase/polyamine system and mediates preconditioning cardioprotection.

    Akt and Erk1/2 activate the ornithine decarboxylase/polyamine system in cardioprotective ischemic preconditioning in rats: the role of mitochondrial permeability transition pores.
    Zhang H, Xue G, Zhang W, Wang L, Li H, Zhang L, Lu F, Bai S, Lin Y, Lou Y, Xu C, Zhao Y.

    12/6/2014
    The modulation of ODC activity by AMPK represents a mechanism that may contribute to control cell growth processes.

    Evidence that AMP-activated protein kinase can negatively modulate ornithine decarboxylase activity in cardiac myoblasts.
    Passariello CL, Gottardi D, Cetrullo S, Zini M, Campana G, Tantini B, Pignatti C, Flamigni F, Guarnieri C, Caldarera CM, Stefanelli C.

    11/17/2012
    effect of deep hypothermia on the ODC activity

    The effect of hypothermia on the ornithine decarboxylase activity in tissues of rats.
    Aksenova GE, Logvinovich OS, Fialkovskaya LA, Afanasyev VN, Ignat'ev DA, Kolomiytseva IK, Fesenko E E.

    10/30/2010
    Overexpression of ornithine decarboxylase increases myogenic potential of rat myoblasts.

    Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts.
    Govoni M, Bonavita F, Shantz LM, Guarnieri C, Giordano E.

    06/14/2010
    Results show that transglutaminase-catalyzed polyamination of rhoA regulates its activity, and that ornithine decarboxylase influences the intracellular distribution of rhoA.

    Ornithine decarboxylase regulates the activity and localization of rhoA via polyamination.
    Mäkitie LT, Kanerva K, Andersson LC.

    01/21/2010
    The tumor-like proliferation of synoviocytes from AA rat joint might be related to the increased mRNAs of C-myc and ODC genes.

    [The study on the relationship between the tumor-like proliferation of synoviocytes and the expression of c-myc and ODC genes in adjuvant arthritis rats].
    Meng M, Gu LG, Zhang Q, Xie H, Wang QG.

    01/21/2010
    ODC is necessary for hyperresponsiveness of the proximal tubule to dietary salt and for the paradoxical effect of dietary salt on GFR in early diabetes

    Ornithine decarboxylase inhibitor eliminates hyperresponsiveness of the early diabetic proximal tubule to dietary salt.
    Miracle CM, Rieg T, Mansoury H, Vallon V, Thomson SC., Free PMC Article

    01/21/2010
    The aim of this study was to investigate the role of TG2, ODC, and their products in regenerating rat liver after partial hepatectomy by using retinoic acid.

    Effect of retinoic acid on transglutaminase and ornithine decarboxylase activities during liver regeneration.
    Ohtake Y, Maruko A, Ohishi N, Kawaguchi M, Satoh T, Ohkubo Y.

    01/21/2010
    Corticosterone decreases ODC mRNA and enzyme protein both in the intact liver and the regenerating liver.

    Regulatory effects of corticosterone on ornithine decarboxylase activity during liver regeneration in rats.
    Ning Q, Li C, Wei K, He J, Xu C, Shao Q.

    01/21/2010
    Spermidine induces precocious maturation of glucose transporters in the small intestine, which may be mediated by alterations in ODC expression.

    Oral polyamine administration modifies the ontogeny of hexose transporter gene expression in the postnatal rat intestine.
    Wild GE, Searles LE, Koski KG, Drozdowski LA, Begum-Hasan J, Thomson AB.

    01/21/2010
    temporal profile of renal ODC protein expression and localization, intrarenal polyamine levels, and sites of proliferation in kidneys of rats during the first 7 days of streptozotocin diabetes

    Increased expression of ornithine decarboxylase in distal tubules of early diabetic rat kidneys: are polyamines paracrine hypertrophic factors?
    Deng A, Munger KA, Valdivielso JM, Satriano J, Lortie M, Blantz RC, Thomson SC.

    01/21/2010
    The induction of polyamine transport in hypoxic pulmonary artery endothelial cells thus seems to require decreased ODC activity as an initiating event.

    Regulation of ornithine decarboxylase and polyamine import by hypoxia in pulmonary artery endothelial cells.
    Babal P, Ruchko M, Ault-Ziel K, Cronenberg L, Olson JW, Gillespie MN.

    01/21/2010
    Impaired ODC activity and polyamine production in the kidney may exaggerate salt-sensitive hypertension in Dahl salt sensitive rats.

    Decreased ornithine decarboxylase activity in the kidneys of Dahl salt-sensitive rats.
    Hayashi T, Tsujino T, Iwata S, Nonaka H, Emoto N, Yano Y, Otani S, Hayashi Y, Itoh H, Yokoyama M.

    01/21/2010
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