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    Il1b interleukin 1 beta [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24494, updated on 1-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Up-regulation of IL-1beta and sPLA2-III in the medial prefrontal cortex contributes to orofacial and somatic hyperalgesia induced by malocclusion via glial-neuron crosstalk.

    Up-regulation of IL-1β and sPLA2-III in the medial prefrontal cortex contributes to orofacial and somatic hyperalgesia induced by malocclusion via glial-neuron crosstalk.
    Feng HN, Zhong LQ, Xu CX, Wang TT, Wu H, Wang L, Traub RJ, Chen X, Cao DY.

    09/24/2024
    Ex Vivo Production of IL-1beta and IL-10 by Activated Blood Cells of Wistar Rats with Different Resistance to Hypoxia after Systemic Inflammatory Response Syndrome.

    Ex Vivo Production of IL-1β and IL-10 by Activated Blood Cells of Wistar Rats with Different Resistance to Hypoxia after Systemic Inflammatory Response Syndrome.
    Kosyreva AM, Dzhalilova DS, Tsvetkov IS, Makarova MA, Makarova OV.

    01/30/2024
    Interleukin-1beta and inflammasome expression in spinal cord following chronic constriction injury in male and female rats.

    Interleukin-1beta and inflammasome expression in spinal cord following chronic constriction injury in male and female rats.
    Green-Fulgham SM, Ball JB, Kwilasz AJ, Harland ME, Frank MG, Dragavon JM, Grace PM, Watkins LR.,

    12/26/2023
    TXNIP activates NLRP3/IL-1beta and participate in inflammatory response and oxidative stress to promote deep venous thrombosis.

    TXNIP activates NLRP3/IL-1β and participate in inflammatory response and oxidative stress to promote deep venous thrombosis.
    Fei J, Wang H, Han J, Zhang X, Ma H, Qin X, Yu C, Jiang J., Free PMC Article

    12/23/2023
    ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic Female NOD Mice and Is Rapidly Upregulated by NF-kappaB in Pancreatic beta-Cells.

    ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic Female NOD Mice and Is Rapidly Upregulated by NF-κB in Pancreatic β-Cells.
    Martin TM, Burke SJ, Batdorf HM, Burk DH, Ghosh S, Dupuy SD, Karlstad MD, Collier JJ., Free PMC Article

    11/13/2023
    Swimming exercise improves SIRT1, NF-kappaB, and IL-1beta protein levels and pancreatic tissue injury in ovariectomized diabetic rats.

    Swimming exercise improves SIRT1, NF-κB, and IL-1β protein levels and pancreatic tissue injury in ovariectomized diabetic rats.
    Habibi P, Ahmadiasl N, Nourazarian A, Yousefi H.

    10/8/2022
    Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1beta/KCC2 signaling during early development.

    Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development.
    Zhang D, Yang Y, Yang Y, Liu J, Zhu T, Huang H, Zhou C., Free PMC Article

    07/30/2022
    Dopaminergic neuronal death in the substantia nigra associates with change in serum levels of TNF-alpha and IL-1beta; evidence from early experimental model of Parkinson's disease.

    Dopaminergic neuronal death in the substantia nigra associates with change in serum levels of TNF-α and IL-1β; evidence from early experimental model of Parkinson's disease.
    Piri H, Sharifi S, Nigjeh S, Haghdoost-Yazdi H.

    06/18/2022
    MAPK p38/Ulk1 pathway inhibits autophagy and induces IL-1beta expression in hepatic stellate cells.

    MAPK p38/Ulk1 pathway inhibits autophagy and induces IL-1β expression in hepatic stellate cells.
    Jin L, Li J, Yang S, Zhang R, Hu C, Chen Y, Tian Z, Ma W, Feng Y, Liu N, Liu J, Yang Y, Chen T, Zhao Y, He Y, Yan T.

    05/7/2022
    Inhibition of the NLRP3/IL-1beta axis protects against sepsis-induced cardiomyopathy.

    Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
    Busch K, Kny M, Huang N, Klassert TE, Stock M, Hahn A, Graeger S, Todiras M, Schmidt S, Chamling B, Willenbrock M, Groß S, Biedenweg D, Heuser A, Scheidereit C, Butter C, Felix SB, Otto O, Luft FC, Slevogt H, Fielitz J., Free PMC Article

    02/5/2022
    InterleukinIbeta promotes cartilage degeneration by regulating forkhead box protein O4 and type collagen.

    Interleukin‑Iβ promotes cartilage degeneration by regulating forkhead box protein O4 and type Ⅱ collagen.
    Wu J, Zhang H, Deng R, Xing L, Hu M, Fu X., Free PMC Article

    01/22/2022
    Vagotomy and Splenectomy Reduce Insulin Secretion and Interleukin-1beta.

    Vagotomy and Splenectomy Reduce Insulin Secretion and Interleukin-1β.
    Siqueira BS, Ceglarek VM, Gomes ECZ, Vettorazzi JF, Rentz T, Nenevê JZ, Volinski KZ, Moraes SS, Malta A, de Freitas Mathias PC, de Oliveira Emilio HR, Balbo SL, Grassiolli S.

    01/22/2022
    Exercise induced hypoalgesia profile in rats is associated with IL-10 and IL-1 beta levels and pain severity following nerve injury.

    Exercise induced hypoalgesia profile in rats is associated with IL-10 and IL-1 β levels and pain severity following nerve injury.
    Khan J, Wang Q, Ren Y, Eliav R, Korczeniewska OA, Benoliel R, Eliav E.

    01/22/2022
    Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine.

    Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine.
    Wang YC, Chiu WC, Cheng CN, Lee C, Chih Wei Huang A.

    01/15/2022
    Adipose-Derived Extract Suppresses IL-1beta-Induced Inflammatory Signaling Pathways in Human Chondrocytes and Ameliorates the Cartilage Destruction of Experimental Osteoarthritis in Rats.

    Adipose-Derived Extract Suppresses IL-1β-Induced Inflammatory Signaling Pathways in Human Chondrocytes and Ameliorates the Cartilage Destruction of Experimental Osteoarthritis in Rats.
    Ohashi H, Nishida K, Yoshida A, Nasu Y, Nakahara R, Matsumoto Y, Takeshita A, Kaneda D, Saeki M, Ozaki T., Free PMC Article

    10/23/2021
    Hypothyroidism Induces Interleukin-1-Dependent Autophagy Mechanism as a Key Mediator of Hippocampal Neuronal Apoptosis and Cognitive Decline in Postnatal Rats.

    Hypothyroidism Induces Interleukin-1-Dependent Autophagy Mechanism as a Key Mediator of Hippocampal Neuronal Apoptosis and Cognitive Decline in Postnatal Rats.
    Mishra J, Vishwakarma J, Malik R, Gupta K, Pandey R, Maurya SK, Garg A, Shukla M, Chattopadhyay N, Bandyopadhyay S.

    10/16/2021
    Cytokines in the colon, central nervous system and serum of irritable bowel syndrome rats.

    Cytokines in the colon, central nervous system and serum of irritable bowel syndrome rats.
    Chao G, Wang Z, Chen X, Zhang S., Free PMC Article

    10/16/2021
    Elevated intracranial pressure induces IL1beta and IL18 overproduction via activation of the NLRP3 inflammasome in microglia of ischemic adult rats.

    Elevated intracranial pressure induces IL‑1β and IL‑18 overproduction via activation of the NLRP3 inflammasome in microglia of ischemic adult rats.
    Ding H, Li Y, Wen M, Liu X, Han Y, Zeng H., Free PMC Article

    07/17/2021
    Omega-3 PUFAs Suppress IL-1beta-Induced Hyperactivity of Immunoproteasomes in Astrocytes.

    Omega-3 PUFAs Suppress IL-1β-Induced Hyperactivity of Immunoproteasomes in Astrocytes.
    Zgorzynska E, Dziedzic B, Markiewicz M, Walczewska A., Free PMC Article

    06/26/2021
    Cardamonin protects nucleus pulposus cells against IL-1beta-induced inflammation and catabolism via Nrf2/NF-kappaB axis.

    Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
    Xie C , Ma H , Shi Y , Li J , Wu H , Wang B , Shao Z , Huang C , Chen J , Sun L , Zhou Y , Tian N , Wu Y , Gao W , Wu A , Wang X , Zhang X .

    06/5/2021
    Simiaosan alleviates the symptoms of gouty arthritis via the NALP3/IL1beta pathway.

    Simiaosan alleviates the symptoms of gouty arthritis via the NALP3/IL‑1β pathway.
    Zhang X, Ding H, Hu G, Lu Y., Free PMC Article

    05/22/2021
    Protective effects of curcumin against rat intestinal inflammationrelated motility disorders.

    Protective effects of curcumin against rat intestinal inflammation‑related motility disorders.
    Yao Y, Luo R, Xiong S, Zhang C, Zhang Y., Free PMC Article

    05/8/2021
    Effects of exercise modalities on BDNF and IL-1beta content in circulating total extracellular vesicles and particles obtained from aged rats.

    Effects of exercise modalities on BDNF and IL-1β content in circulating total extracellular vesicles and particles obtained from aged rats.
    Barcellos N, Cechinel LR, de Meireles LCF, Lovatel GA, Bruch GE, Carregal VM, Massensini AR, Dalla Costa T, Pereira LO, Siqueira IR.

    05/8/2021
    Chronic intrahippocampal interleukin-1beta overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition.

    Chronic intrahippocampal interleukin-1β overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition.
    Pawley LC, Hueston CM, O'Leary JD, Kozareva DA, Cryan JF, O'Leary OF, Nolan YM.

    03/13/2021
    Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model.

    Blocking Interleukin-1 Beta Reduces the Evolution of Thoracic Aortic Dissection in a Rodent Model.
    Guo LL, Wu MT, Zhang LW, Chu YX, Tian P, Jing ZP, Li JS, Sun YD, Yeung KK, Zhang L.

    02/13/2021
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