| Exosomal Hsp27 protein are associated with heart failure in STZ-induced type 1 diabetic rats. | Exosomal Hsp27 protein are associated with heart failure in STZ-induced type 1 diabetic rats.
Li C, Kuang J, Wang X, Zhang G, Hong M, Cheng G, Zhao T. | 08/26/2024 |
| Hspb1 and Lgals3 in spinal neurons are closely associated with autophagy following excitotoxicity based on machine learning algorithms. | Hspb1 and Lgals3 in spinal neurons are closely associated with autophagy following excitotoxicity based on machine learning algorithms.
Yan L, Li Z, Li C, Chen J, Zhou X, Cui J, Liu P, Shen C, Chen C, Hong H, Xu G, Cui Z., Free PMC Article | 06/6/2024 |
| Overexpression of HSP27 accelerates stress-induced gastric ulcer healing via the CXCL12/CXCR4 axis. | Overexpression of HSP27 accelerates stress-induced gastric ulcer healing via the CXCL12/CXCR4 axis.
Lu Q, Tang H. | 04/5/2024 |
| HSP27 Modulates Neuropathic Pain by Inhibiting P2X3 Degradation. | HSP27 Modulates Neuropathic Pain by Inhibiting P2X3 Degradation.
Yeh TY, Chang MF, Kan YY, Chiang H, Hsieh ST. | 02/15/2024 |
| Mechanistic insights into the anti-restenotic effects of HSP27 and HO1 modulated by reconstituted HDL on neointimal hyperplasia. | Mechanistic insights into the anti-restenotic effects of HSP27 and HO1 modulated by reconstituted HDL on neointimal hyperplasia.
Kim YJ, Khaleel ZH, Jin M, Lee JWY, Park S, Ga S, Kim NH, Sa DH, Kang ES, Han SH, Lee JY, Ku HJ, Kim SW, Kim KY, Park JE, Kim YH, Lee BS., Free PMC Article | 12/20/2023 |
| Injury-Induced HSP27 Expression in Peripheral Nervous Tissue Is Not Associated with Any Alteration in Axonal Outgrowth after Immediate or Delayed Nerve Repair. | Injury-Induced HSP27 Expression in Peripheral Nervous Tissue Is Not Associated with Any Alteration in Axonal Outgrowth after Immediate or Delayed Nerve Repair.
Stenberg L, Hazer Rosberg DB, Kohyama S, Suganuma S, Dahlin LB., Free PMC Article | 09/18/2021 |
| Up-regulation of heat shock protein 27 inhibits apoptosis in lumbosacral nerve root avulsion-induced neurons. | Up-regulation of heat shock protein 27 inhibits apoptosis in lumbosacral nerve root avulsion-induced neurons.
Zhou ZB, Huang GX, Lu JJ, Ma J, Yuan QJ, Cao Y, Zhu L., Free PMC Article | 10/31/2020 |
| Via regulation of HSP27 and HSP70. | Trehalose protects against spinal cord injury through regulating heat shock proteins 27 and 70 and caspase-3 genes expression.
Nasouti R, Khaksari M, Mirzaee M, Nazari-Robati M. | 06/20/2020 |
| Hsp27 inhibited UVB-induced apoptosis through regulating bax and bcl-2 expression. | The effects of HSP27 against UVB-induced photoaging in rat skin.
Liu Y, Huang X, Wang P, Pan Y, Cao D, Liu C, Chen A. | 04/11/2020 |
| HSPB1 promoted the reduced state of endogenous antioxidant pathways following oxidative stress in H9c2 cardiac myocytes and improved the redox state of the cytoplasm via modulation of the Hippo signaling pathway. | Heat-shock protein B1 upholds the cytoplasm reduced state to inhibit activation of the Hippo pathway in H9c2 cells.
Liu X, Liu K, Li C, Cai J, Huang L, Chen H, Wang H, Zou J, Liu M, Wang K, Tan S, Zhang H. | 03/21/2020 |
| The mechanism was validated in animal experiments. Zhenbao Pill regulated TUG1/miR-214/HSP27 signaling pathway to reduce Treg cell proportion and thus relieve acute Acute spinal cord injury (SCI) | Zhenbao Pill reduces Treg cell proportion in acute spinal cord injury rats by regulating TUG1/miR-214/HSP27 axis.
He Y, Li M, Wujisiguleng, Lv B, Huan Y, Liu B, Wang D, Yu H, Zhang L, Shi Z., Free PMC Article | 07/27/2019 |
| HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis. | HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.
Kennedy D, Mnich K, Oommen D, Chakravarthy R, Almeida-Souza L, Krols M, Saveljeva S, Doyle K, Gupta S, Timmerman V, Janssens S, Gorman AM, Samali A., Free PMC Article | 04/28/2018 |
| These data suggest that among all small heat shock proteins, HspB1 and alpha(B)-crystallin might be most important in the neuronal stress response to ischemia/reperfusion injury in the brain since their protein levels were upregulated to the highest extent after transient middle cerebral artery occlusion. | Upregulation and phosphorylation of HspB1/Hsp25 and HspB5/αB-crystallin after transient middle cerebral artery occlusion in rats.
Bartelt-Kirbach B, Slowik A, Beyer C, Golenhofen N., Free PMC Article | 03/24/2018 |
| activation of the A1 adenosine receptor by N(6)-cyclohexyladenosine could prevent intracerebral hemorrhage-induced secondary brain injury via the P38-MAPKAP2-Hsp27 pathway. | A1 adenosine receptor attenuates intracerebral hemorrhage-induced secondary brain injury in rats by activating the P38-MAPKAP2-Hsp27 pathway.
Zhai W, Chen D, Shen H, Chen Z, Li H, Yu Z, Chen G., Free PMC Article | 11/11/2017 |
| HSP27 suppression may initiate a protective effect for retinal cells, particularly photoreceptors, from light-induced retinal degeneration. | Suppression of HSP27 Restores Retinal Function and Protects Photoreceptors From Apoptosis in a Light-Induced Retinal Degeneration Animal Model.
Chien CC, Huang CJ, Tien LT, Cheng YC, Ke CY, Lee YJ. | 07/22/2017 |
| Exercise-related elevations of body temperature could be the only factor for the inductions of adrenal Hsp72 and Hsp25 expression. | Short-term treadmill exercise in a cold environment does not induce adrenal Hsp72 and Hsp25 expression.
Akin S, Naito H, Ogura Y, Ichinoseki-Sekine N, Kurosaka M, Kakigi R, Demirel HA., Free PMC Article | 07/15/2017 |
| These results were confirmed by analysis with STRING 9.1 software, which indicated that Hsp27 and aB-crystallin are co-expressed in rat myocardial cells | Expression profiles of heat shock protein 27 and αB-crystallin and their effects on heat-stressed rat myocardial cells in vitro and in vivo.
Tang S, Chen H, Cheng Y, Nasir MA, Kemper N, Bao E. | 10/29/2016 |
| data suggest that HspB1 and HspB5 might be of protective value for retinal ganglion cells after optic nerve injury and that this process might be regulated by phosphorylation at serine 86 of HspB1 and serine 19 and serine 45 of HspB5. | Induction and phosphorylation of the small heat shock proteins HspB1/Hsp25 and HspB5/αB-crystallin in the rat retina upon optic nerve injury.
Schmidt T, Fischer D, Andreadaki A, Bartelt-Kirbach B, Golenhofen N., Free PMC Article | 10/1/2016 |
| The findings of the present study augment the understanding of the involvement of Hsp27 and Hsp70 in the response of the visual system to retinal ganglion cells degeneration. | Expression of inducible heat shock proteins Hsp27 and Hsp70 in the visual pathway of rats subjected to various models of retinal ganglion cell injury.
Chidlow G, Wood JP, Casson RJ., Free PMC Article | 03/5/2016 |
| cardiac HMGB1 increases HSPB1 expression and attenuates cardiomyocyte apoptosis associated with doxorubicin-induced cardiomyopathy. | High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis.
Narumi T, Shishido T, Otaki Y, Kadowaki S, Honda Y, Funayama A, Honda S, Hasegawa H, Kinoshita D, Yokoyama M, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Tanaka A, Woo CH, Abe J, Takeishi Y, Kubota I. | 01/16/2016 |
| p-HSP27 supports endothelial barrier function with the promotion of central F-actin. Phosphatases and MK2 sumoylation contribute to the blunting of HSP27 phosphorylation. | HSP27 phosphorylation protects against endothelial barrier dysfunction under burn serum challenge.
Sun HB, Ren X, Liu J, Guo XW, Jiang XP, Zhang DX, Huang YS, Zhang JP. | 09/12/2015 |
| The level of Hsp27 positively correlates with the amount of insoluble tau in the brain. | Intraneuronal accumulation of misfolded tau protein induces overexpression of Hsp27 in activated astrocytes.
Filipcik P, Cente M, Zilka N, Smolek T, Hanes J, Kucerak J, Opattova A, Kovacech B, Novak M. | 08/29/2015 |
| Celastrol induces Hsp32 expression in glial cells in cerebral cortical cultures. | Localization of heat shock proteins in cerebral cortical cultures following induction by celastrol.
Chow AM, Tang DW, Hanif A, Brown IR., Free PMC Article | 07/4/2015 |
| is suggested that renal protective effect may be related to the levels of HSP27 in the reduction of renal ischemia-reperfusion injury by ischemic postconditioning | Roles of MAPKAPK-2 and HSP27 in the reduction of renal ischemia-reperfusion injury by ischemic postconditioning in rats.
Xia A, Li Y, Li N, Xue Z, Xia J, Wei T, Cao J. | 04/25/2015 |
| Cytoskeletal reorganization evoked by Rho-associated kinase- and protein kinase C-catalyzed phosphorylation of cofilin and heat shock protein 27, respectively, contributes to myogenic constriction of rat cerebral arteries. | Cytoskeletal reorganization evoked by Rho-associated kinase- and protein kinase C-catalyzed phosphorylation of cofilin and heat shock protein 27, respectively, contributes to myogenic constriction of rat cerebral arteries.
Moreno-Domínguez A, El-Yazbi AF, Zhu HL, Colinas O, Zhong XZ, Walsh EJ, Cole DM, Kargacin GJ, Walsh MP, Cole WC., Free PMC Article | 02/14/2015 |