A novel heterozygous missense variant of PANX1 causes human oocyte death and female infertility. | A novel heterozygous missense variant of PANX1 causes human oocyte death and female infertility. Zhou J, Mao R, Wang M, Long R, Gao L, Wang X, Jin L, Zhu L., Free PMC Article | 09/5/2024 |
Human pannexin 1 channel is not phosphorylated by Src tyrosine kinase at Tyr199 and Tyr309. | Human pannexin 1 channel is not phosphorylated by Src tyrosine kinase at Tyr199 and Tyr309. Ruan Z, Lee J, Li Y, Du J, Lü W., Free PMC Article | 09/4/2024 |
Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death. | Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death. Xiong Y, Luo J, Hong ZY, Zhu WZ, Hu A, Song BL., Free PMC Article | 08/14/2024 |
Pannexin-1 expression in tumor cells correlates with colon cancer progression and survival. | Pannexin-1 expression in tumor cells correlates with colon cancer progression and survival. Fierro-Arenas A, Landskron G, Camhi-Vainroj I, Basterrechea B, Parada-Venegas D, Lobos-González L, Dubois-Camacho K, Araneda C, Romero C, Domínguez A, Vásquez G, López-K F, Alvarez K, González CM, Hager Ribeiro C, Balboa E, Eugenin E, Hermoso MA, De la Fuente López M. | 07/8/2024 |
PANX1-mediated ATP release confers FAM3A's suppression effects on hepatic gluconeogenesis and lipogenesis. | PANX1-mediated ATP release confers FAM3A's suppression effects on hepatic gluconeogenesis and lipogenesis. Hu CQ, Hou T, Xiang R, Li X, Li J, Wang TT, Liu WJ, Hou S, Wang D, Zhao QH, Yu XX, Xu M, Liu XK, Chi YJ, Yang JC., Free PMC Article | 07/2/2024 |
Ca[2+] permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death. | Ca(2+) permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death. Salgado M, Márquez-Miranda V, Ferrada L, Rojas M, Poblete-Flores G, González-Nilo FD, Ardiles ÁO, Sáez JC., | 06/15/2024 |
Reduced Ca[2+] mobilization in neonatal human platelets involves SARAF and pannexin-1. | Reduced Ca(2+) mobilization in neonatal human platelets involves SARAF and pannexin-1. Rosado JA. | 03/15/2024 |
Differential activation of mouse and human Panx1 channel variants. | Differential activation of mouse and human Panx1 channel variants. Cibelli A, Dohare P, Spray DC, Scemes E., Free PMC Article | 12/26/2023 |
Pannexin 1 Modulates Angiogenic Activities of Human Endothelial Colony-Forming Cells Through IGF-1 Mechanism and Is a Marker of Senescence. | Pannexin 1 Modulates Angiogenic Activities of Human Endothelial Colony-Forming Cells Through IGF-1 Mechanism and Is a Marker of Senescence. Tien TY, Wu YJ, Su CH, Hsieh CL, Wang BJ, Lee YN, Su Y, Yeh HI. | 09/29/2023 |
Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels. | Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels. Wu YL, Yang AH, Chiu YH. | 09/12/2023 |
Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and [10]Panx1 Peptides. | Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and (10)Panx1 Peptides. Lissoni A, Tao S, Allewaert R, Witschas K, Leybaert L., Free PMC Article | 08/19/2023 |
Expression of pannexin1 in lung cancer brain metastasis and immune microenvironment. | Expression of pannexin1 in lung cancer brain metastasis and immune microenvironment. Abdo R, Bholat A, Jackson-Boeters L, Johnston D, Penuela S, Zhang Q. | 06/28/2023 |
Carboxyl terminus of Pannexin-1 plays a crucial role in P2X7 receptor-mediated signaling. | Carboxyl terminus of Pannexin-1 plays a crucial role in P2X7 receptor-mediated signaling. Purohit R, Bera AK. | 06/12/2023 |
Increased serum pannexin-1 concentrations reflect illness severity and predict a poor prognosis after acute supratentorial intracerebral hemorrhage: A prospective longitudinal cohort study. | Increased serum pannexin-1 concentrations reflect illness severity and predict a poor prognosis after acute supratentorial intracerebral hemorrhage: A prospective longitudinal cohort study. Zhang L, Xie Q, Hong H, Wang X, Miao L, Zhang X. | 03/1/2023 |
A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death. | A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death. Zhou J, Wang M, Hu J, Li Z, Zhu L, Jin L., Free PMC Article | 01/21/2023 |
Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies. | Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies. Zhou B, Ryder CB, Dubyak GR, Abbott DW., Free PMC Article | 12/24/2022 |
A2A receptor-induced overexpression of pannexin-1 channels indirectly mediates adenosine fibrogenic actions by favouring ATP release from human subcutaneous fibroblasts. | A(2A) receptor-induced overexpression of pannexin-1 channels indirectly mediates adenosine fibrogenic actions by favouring ATP release from human subcutaneous fibroblasts. Herman-de-Sousa C, Costa MA, Silva RP, Ferreirinha F, Ribeiro S, Correia-de-Sá P. | 11/19/2022 |
Activity and Stability of Panx1 Channels in Astrocytes and Neuroblastoma Cells Are Enhanced by Cholesterol Depletion. | Activity and Stability of Panx1 Channels in Astrocytes and Neuroblastoma Cells Are Enhanced by Cholesterol Depletion. Cibelli A, Scemes E, Spray DC., Free PMC Article | 11/5/2022 |
ER-resident STIM1/2 couples Ca(2+) entry by NMDA receptors to pannexin-1 activation. | ER-resident STIM1/2 couples Ca(2+) entry by NMDA receptors to pannexin-1 activation. Patil CS, Li H, Lavine NE, Shi R, Bodalia A, Siddiqui TJ, Jackson MF., Free PMC Article | 09/3/2022 |
Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells. | Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells. Rougé S, Genetet S, Leal Denis MF, Dussiot M, Schwarzbaum PJ, Ostuni MA, Mouro-Chanteloup I., Free PMC Article | 09/3/2022 |
A novel heterozygous variant in PANX1 is associated with oocyte death and female infertility. | A novel heterozygous variant in PANX1 is associated with oocyte death and female infertility. Wu XW, Liu PP, Zou Y, Xu DF, Zhang ZQ, Cao LY, Lu-Fan, Xia LZ, Huang JL, Chen J, Xin CL, Huang ZH, Tan J, Wu QF, Li ZM., Free PMC Article | 09/3/2022 |
Pannexin1 inhibits autophagy of cisplatin-resistant testicular cancer cells by mediating ATP release. | Pannexin1 inhibits autophagy of cisplatin-resistant testicular cancer cells by mediating ATP release. Yuan M, Yao Y, Wu D, Zhu C, Dong S, Tong X., Free PMC Article | 07/23/2022 |
Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Kuzuya M, Hirano H, Hayashida K, Watanabe M, Kobayashi K, Terada T, Mahmood MI, Tama F, Tani K, Fujiyoshi Y, Oshima A. | 07/16/2022 |
Pannexin-1 Activation by Phosphorylation Is Crucial for Platelet Aggregation and Thrombus Formation. | Pannexin-1 Activation by Phosphorylation Is Crucial for Platelet Aggregation and Thrombus Formation. Metz LM, Elvers M., Free PMC Article | 05/28/2022 |
Novel insights into the SLC7A11-mediated ferroptosis signaling pathways in preeclampsia patients: identifying pannexin 1 and toll-like receptor 4 as innovative prospective diagnostic biomarkers. | Novel insights into the SLC7A11-mediated ferroptosis signaling pathways in preeclampsia patients: identifying pannexin 1 and toll-like receptor 4 as innovative prospective diagnostic biomarkers. El-Khalik SRA, Ibrahim RR, Ghafar MTA, Shatat D, El-Deeb OS., Free PMC Article | 05/28/2022 |