| Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma. | Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma.
Jiang Y, Zhang C, Zhang J, Han D, Shi X. | 03/19/2022 |
| IFIT5 Negatively Regulates the Type I IFN Pathway by Disrupting TBK1-IKKepsilon-IRF3 Signalosome and Degrading IRF3 and IKKepsilon. | IFIT5 Negatively Regulates the Type I IFN Pathway by Disrupting TBK1-IKKε-IRF3 Signalosome and Degrading IRF3 and IKKε.
Zhang N, Shi H, Yan M, Liu G. | 08/28/2021 |
| Development of bis-ANS-based modified fluorescence titration assay for IFIT/RNA studies. | Development of bis-ANS-based modified fluorescence titration assay for IFIT/RNA studies.
Dobieżyńska A, Miszkiewicz J, Darżynkiewicz ZM, Tyras M, Stankiewicz-Drogoń A, Trylska J, Darżynkiewicz E, Grzela R. | 03/20/2021 |
| Expression of interferon induced protein with tetratricopeptide repeats 5 (IFIT5) is positively correlated with pathological characteristics, and predicts a poor prognosis of bladder cancer patients. | The roles and mechanism of IFIT5 in bladder cancer epithelial-mesenchymal transition and progression.
Huang J, Lo UG, Wu S, Wang B, Pong RC, Lai CH, Lin H, He D, Hsieh JT, Wu K., Free PMC Article | 07/11/2020 |
| IFIT5 promotes SeV-induced IKK phosphorylation and NF-kappaB activation by regulating the recruitment of IKK to TAK1. | IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1).
Zheng C, Zheng Z, Zhang Z, Meng J, Liu Y, Ke X, Hu Q, Wang H. | 09/24/2016 |
| show that IFIT5 binds precursor and processed tRNAs, as well as other RNA polymerase III transcripts. Our findings establish the RNA recognition specificity of the human innate immune response protein IFIT5 | Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5.
Katibah GE, Qin Y, Sidote DJ, Yao J, Lambowitz AM, Collins K., Free PMC Article | 11/8/2014 |
| TRIF-N-terminal helical domain shares structural similarity with IFIT5. | The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins.
Ullah MO, Ve T, Mangan M, Alaidarous M, Sweet MJ, Mansell A, Kobe B. | 07/12/2014 |
| IFIT5 consists of 24 alpha-helices that pack into a special "V"-like structure. | Crystal structure and nucleotide selectivity of human IFIT5/ISG58.
Feng F, Yuan L, Wang YE, Crowley C, Lv Z, Li J, Liu Y, Cheng G, Zeng S, Liang H., Free PMC Article | 03/8/2014 |
| IFIT5 recognizes cellular RNA instead of protein partners. | tRNA binding, structure, and localization of the human interferon-induced protein IFIT5.
Katibah GE, Lee HJ, Huizar JP, Vogan JM, Alber T, Collins K., Free PMC Article | 04/20/2013 |
| crystal structures of human IFIT5, its complex with PPP-RNAs, and an amino-terminal fragment of IFIT1 | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Abbas YM, Pichlmair A, Górna MW, Superti-Furga G, Nagar B., Free PMC Article | 03/9/2013 |
| Observational study of gene-disease association. (HuGE Navigator) | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A., Free PMC Article | 12/2/2009 |