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    Zeb2 zinc finger E-box binding homeobox 2 [ Mus musculus (house mouse) ]

    Gene ID: 24136, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.

    N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
    Cai Y, Zhou J, Xu A, Huang J, Zhang H, Xie G, Zhong K, Wu Y, Ye P, Wang H, Niu H., Free PMC Article

    10/17/2024
    ABCs begin with ZEB2.

    ABCs begin with ZEB2.
    Knox JJ, Cancro MP.

    04/12/2024
    Zeb2 drives the formation of CD11c[+] atypical B cells to sustain germinal centers that control persistent infection.

    Zeb2 drives the formation of CD11c(+) atypical B cells to sustain germinal centers that control persistent infection.
    Gao X, Shen Q, Roco JA, Dalton B, Frith K, Munier CML, Ballard FD, Wang K, Kelly HG, Nekrasov M, He JS, Jaeger R, Carreira P, Ellyard JI, Beattie L, Enders A, Cook MC, Zaunders JJ, Cockburn IA.

    04/3/2024
    The transcription factor ZEB2 drives the formation of age-associated B cells.

    The transcription factor ZEB2 drives the formation of age-associated B cells.
    Dai D, Gu S, Han X, Ding H, Jiang Y, Zhang X, Yao C, Hong S, Zhang J, Shen Y, Hou G, Qu B, Zhou H, Qin Y, He Y, Ma J, Yin Z, Ye Z, Qian J, Jiang Q, Wu L, Guo Q, Chen S, Huang C, Kottyan LC, Weirauch MT, Vinuesa CG, Shen N., Free PMC Article

    02/1/2024
    The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.

    The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.
    Ninfali C, Cortés M, Martínez-Campanario MC, Domínguez V, Han L, Tobías E, Esteve-Codina A, Enrich C, Pintado B, Garrabou G, Postigo A., Free PMC Article

    11/14/2023
    miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosis.

    miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosis.
    Chen F, Ning Y, Liu J, Lian M, Wang J, Dan H., Free PMC Article

    08/24/2023
    Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration.

    Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration.
    Luo S, Kong C, Zhao S, Tang X, Wang Y, Zhou X, Li R, Liu X, Tang X, Sun S, Xie W, Zhang ZR, Jing Q, Gu A, Chen F, Wang D, Wang H, Han Y, Xie L, Ji Y.

    05/12/2023
    Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome.

    Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome.
    Birkhoff JC, Korporaal AL, Brouwer RWW, Nowosad K, Milazzo C, Mouratidou L, van den Hout MCGN, van IJcken WFJ, Huylebroeck D, Conidi A., Free PMC Article

    04/14/2023
    Long noncoding RNA MALAT1 inhibition attenuates sepsis-induced acute lung injury through modulating the miR-129-5p/PAX6/ZEB2 axis.

    Long noncoding RNA MALAT1 inhibition attenuates sepsis-induced acute lung injury through modulating the miR-129-5p/PAX6/ZEB2 axis.
    Li Y, Xiao W, Lin X.

    03/7/2023
    Pituitary Stem Cell Regulation by Zeb2 and BMP Signaling.

    Pituitary Stem Cell Regulation by Zeb2 and BMP Signaling.
    Winningham AH, Camper SA., Free PMC Article

    02/22/2023
    ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis.

    ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis.
    Kumar S, Fan X, Rasouly HM, Sharma R, Salant DJ, Lu W., Free PMC Article

    01/21/2023
    miR-200b-3p Induces the Formation of Insulin-Producing Cells from Umbilical Cord Mesenchymal Stem Cells by Targeting ZEB2.

    miR-200b-3p Induces the Formation of Insulin-Producing Cells from Umbilical Cord Mesenchymal Stem Cells by Targeting ZEB2.
    Chen W, Jiang W, Dong J, Wang J, Wang B.

    08/27/2022
    Ablation of cDC2 development by triple mutations within the Zeb2 enhancer.

    Ablation of cDC2 development by triple mutations within the Zeb2 enhancer.
    Liu TT, Kim S, Desai P, Kim DH, Huang X, Ferris ST, Wu R, Ou F, Egawa T, Van Dyken SJ, Diamond MS, Johnson PF, Kubo M, Murphy TL, Murphy KM., Free PMC Article

    07/16/2022
    miR-141-3p protects against blood-brain barrier disruption and brain injury after intracerebral hemorrhage by targeting ZEB2.

    miR-141-3p protects against blood-brain barrier disruption and brain injury after intracerebral hemorrhage by targeting ZEB2.
    Yu M, Tian T, Zhang J, Hu T.

    05/7/2022
    Knockout of Zeb2 ameliorates progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia-reperfusion injury.

    Knockout of Zeb2 ameliorates progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia-reperfusion injury.
    Inotani S, Taniguchi Y, Nakamura K, Nishikawa H, Matsumoto T, Horino T, Fujimoto S, Sano S, Yanagita M, Terada Y.

    03/26/2022
    Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated beta-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.

    Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.
    de Jesus DS, Mak TCS, Wang YF, von Ohlen Y, Bai Y, Kane E, Chabosseau P, Chahrour CM, Distaso W, Salem V, Tomas A, Stoffel M, Rutter GA, Latreille M., Free PMC Article

    03/26/2022
    ZEB2, the Mowat-Wilson Syndrome Transcription Factor: Confirmations, Novel Functions, and Continuing Surprises.

    ZEB2, the Mowat-Wilson Syndrome Transcription Factor: Confirmations, Novel Functions, and Continuing Surprises.
    Birkhoff JC, Huylebroeck D, Conidi A., Free PMC Article

    02/5/2022
    Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis.

    Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis.
    Huang X, Ferris ST, Kim S, Choudhary MNK, Belk JA, Fan C, Qi Y, Sudan R, Xia Y, Desai P, Chen J, Ly N, Shi Q, Bagadia P, Liu T, Guilliams M, Egawa T, Colonna M, Diamond MS, Murphy TL, Satpathy AT, Wang T, Murphy KM., Free PMC Article

    09/18/2021
    Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation.

    Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation.
    Birkhoff JC, Brouwer RWW, Kolovos P, Korporaal AL, Bermejo-Santos A, Boltsis I, Nowosad K, van den Hout MCGN, Grosveld FG, van IJcken WFJ, Huylebroeck D, Conidi A., Free PMC Article

    09/4/2021
    Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury.

    Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury.
    Vivinetto AL, Kim ID, Goldberg DC, Fones L, Brown E, Tarabykin VS, Hill CE, Cho S, Cave JW., Free PMC Article

    05/1/2021
    Zeb2 regulates the balance between retinal interneurons and Muller glia by inhibition of BMP-Smad signaling.

    Zeb2 regulates the balance between retinal interneurons and Müller glia by inhibition of BMP-Smad signaling.
    Menuchin-Lasowski Y, Dagan B, Conidi A, Cohen-Gulkar M, David A, Ehrlich M, Giladi PO, Clark BS, Blackshaw S, Shapira K, Huylebroeck D, Henis YI, Ashery-Padan R., Free PMC Article

    03/13/2021
    Roles of ZEB2 and RBM38 in liver cancer stem cell proliferation.

    Roles of ZEB2 and RBM38 in liver cancer stem cell proliferation.
    Yu X, Wang W, Lin X, Zheng X, Yang A.

    02/13/2021
    Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner.

    Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner.
    Gladka MM, Kohela A, Molenaar B, Versteeg D, Kooijman L, Monshouwer-Kloots J, Kremer V, Vos HR, Huibers MMH, Haigh JJ, Huylebroeck D, Boon RA, Giacca M, van Rooij E., Free PMC Article

    01/16/2021
    Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb.

    Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb.
    Deryckere A, Stappers E, Dries R, Peyre E, van den Berghe V, Conidi A, Zampeta FI, Francis A, Bresseleers M, Stryjewska A, Vanlaer R, Maas E, Smal IV, van IJcken WFJ, Grosveld FG, Nguyen L, Huylebroeck D, Seuntjens E.

    12/26/2020
    Zeb2 Regulates Myogenic Differentiation in Pluripotent Stem Cells.

    Zeb2 Regulates Myogenic Differentiation in Pluripotent Stem Cells.
    Di Filippo ES, Costamagna D, Giacomazzi G, Cortés-Calabuig Á, Stryjewska A, Huylebroeck D, Fulle S, Sampaolesi M., Free PMC Article

    12/19/2020
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