Coronin 1C, Regulated by Multiple microRNAs, Facilitates Cancer Cell Aggressiveness in Pancreatic Ductal Adenocarcinoma. | Coronin 1C, Regulated by Multiple microRNAs, Facilitates Cancer Cell Aggressiveness in Pancreatic Ductal Adenocarcinoma. Fukuda K, Seki N, Yasudome R, Mitsueda R, Asai S, Kato M, Idichi T, Kurahara H, Ohtsuka T., Free PMC Article | 06/2/2023 |
CORO1C, a novel PAK4 binding protein, recruits phospho-PAK4 at serine 99 to the leading edge and promotes the migration of gastric cancer cells. | CORO1C, a novel PAK4 binding protein, recruits phospho-PAK4 at serine 99 to the leading edge and promotes the migration of gastric cancer cells. Li X, Chen M, Yuan Y, Li J, Li F., Free PMC Article | 10/29/2022 |
CircRNA CORO1C Regulates miR-654-3p/USP7 Axis to Mediate Laryngeal Squamous Cell Carcinoma Progression. | CircRNA CORO1C Regulates miR-654-3p/USP7 Axis to Mediate Laryngeal Squamous Cell Carcinoma Progression. Zhang J, Li H, Li J, Ke S. | 09/24/2022 |
Circ_0020123 plays an oncogenic role in non-small cell lung cancer depending on the regulation of miR-512-3p/CORO1C. | Circ_0020123 plays an oncogenic role in non-small cell lung cancer depending on the regulation of miR-512-3p/CORO1C. Zhang H, Huang T, Yuan S, Long Y, Tan S, Niu G, Zhang P, Yang M., Free PMC Article | 05/7/2022 |
Circ_0025039 acts an oncogenic role in the progression of non-small cell lung cancer through miR-636-dependent regulation of CORO1C. | Circ_0025039 acts an oncogenic role in the progression of non-small cell lung cancer through miR-636-dependent regulation of CORO1C. Wang L, Zeng C, Chen Z, Qi J, Huang S, Liang H, Huang S, Ou Z. | 03/26/2022 |
Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis. | Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis. Li J, Tian L, Jing Z, Guo Z, Nan P, Liu F, Zou S, Yang L, Xie X, Zhu Y, Zhao Y, Sun W, Sun Y, Zhao X. | 12/25/2021 |
A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis. | A peptide CORO1C-47aa encoded by the circular noncoding RNA circ-0000437 functions as a negative regulator in endometrium tumor angiogenesis. Li F, Cai Y, Deng S, Yang L, Liu N, Chang X, Jing L, Zhou Y, Li H., Free PMC Article | 12/18/2021 |
Circ_0003998 Regulates the Progression and Docetaxel Sensitivity of DTX-Resistant Non-Small Cell Lung Cancer Cells by the miR-136-5p/CORO1C Axis. | Circ_0003998 Regulates the Progression and Docetaxel Sensitivity of DTX-Resistant Non-Small Cell Lung Cancer Cells by the miR-136-5p/CORO1C Axis. Zhang W, Song C, Ren X., Free PMC Article | 11/27/2021 |
MiR-206 may suppress non-small lung cancer metastasis by targeting CORO1C. | MiR-206 may suppress non-small lung cancer metastasis by targeting CORO1C. Liao M, Peng L., Free PMC Article | 12/5/2020 |
miR-26 suppresses renal cell cancer via down-regulating coronin-3. | miR-26 suppresses renal cell cancer via down-regulating coronin-3. Wang XJ, Yan ZJ, Luo GC, Chen YY, Bai PM. | 03/21/2020 |
CORO1C promoted both proliferation and metastasis, stimulated cellular mitosis and inhibited cell apoptosis in gastric cancer cells. Gastric cancer patients with positive CORO1C expression were associated with poor prognosis and lower survival rate. | CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro. Cheng X, Wang X, Wu Z, Tan S, Zhu T, Ding K., Free PMC Article | 02/29/2020 |
These results identify coronin 1C as a novel player of the multi-faceted mechanism responsible for invadopodia formation, MT1-MMP surface exposure and invasiveness in breast cancer cells. | Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function. Castagnino A, Castro-Castro A, Irondelle M, Guichard A, Lodillinsky C, Fuhrmann L, Vacher S, Agüera-González S, Zagryazhskaya-Masson A, Romao M, El Kesrouani C, Noegel AA, Dubois T, Raposo G, Bear JE, Clemen CS, Vincent-Salomon A, Bièche I, Chavrier P. | 03/2/2019 |
Coronin 1c protein and F-actin protein are highly expressed in breast cancer and their expression may be related to the metastasis of breast cancer cells. | Coronin 1c and F-actin Promote Metastasis of Breast Cancer. Shao J, Zhang H, Wang Z., Free PMC Article | 12/22/2018 |
circBIRC6 and circCORO1C are functionally associated with the pluripotent state in undifferentiated human embryonic stem cells | The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency. Yu CY, Li TC, Wu YY, Yeh CH, Chiang W, Chuang CY, Kuo HC., Free PMC Article | 10/6/2018 |
It would appear that YB-1 could regulate cell invasion and migration via downregulation of its indirect target coronin-1C. The association between YB-1 and coronin-1C offers a novel approach by which metastasis of breast cancer cells could be targeted and abrogated. | YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro. Lim JP, Shyamasundar S, Gunaratne J, Scully OJ, Matsumoto K, Bay BH., Free PMC Article | 02/17/2018 |
findings emphasize the power of genetic modifiers, PLS3 and CORO1C, to unravel the cellular pathomechanisms underlying spinal muscular atrophy (SMA)--and the power of combinatorial therapy based on splice correction of SMN2 and endocytosis improvement to efficiently treat SMA | The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype. Hosseinibarkooie S, Peters M, Torres-Benito L, Rastetter RH, Hupperich K, Hoffmann A, Mendoza-Ferreira N, Kaczmarek A, Janzen E, Milbradt J, Lamkemeyer T, Rigo F, Bennett CF, Guschlbauer C, Büschges A, Hammerschmidt M, Riessland M, Kye MJ, Clemen CS, Wirth B., Free PMC Article | 05/7/2017 |
Data indicate that coronin 1C protein (CORO1C) was a direct target of the microRNA miR-1/133a cluster in EBC-1 CORO1C was a direct target of the miR-1/133a cluster in lung-squamous cell carcinoma cell line EBC-1. | Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C. Mataki H, Enokida H, Chiyomaru T, Mizuno K, Matsushita R, Goto Y, Nishikawa R, Higashimoto I, Samukawa T, Nakagawa M, Inoue H, Seki N. | 04/2/2016 |
Coro1C mediated Rac1 trafficking through actin-rich vesicles. | Integration of the Rac1- and actin-binding properties of Coronin-1C. Tilley FC, Williamson RC, Race PR, Rendall TC, Bass MD., Free PMC Article | 12/5/2015 |
Coronin-1C overexpression is associated withand hepatocellular carcinoma growth through enhancement of tumor cell proliferation and migration, which are correlated with Rac-1 activation. | Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells. Wang ZG, Jia MK, Cao H, Bian P, Fang XD. | 04/12/2014 |
Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K. | Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K. Ren G, Tian Q, An Y, Feng B, Lu Y, Liang J, Li K, Shang Y, Nie Y, Wang X, Fan D., Free PMC Article | 03/23/2013 |
Patients with higher coronin-1C expression had a more advanced stage of hepatocellular carcinoma. | [Increased coronin-1C expression is related to hepatocellular carcinoma invasion and metastasis]. Wu L, Hou JX, Peng CW, Zhang YH, Chen C, Chen LD, Li Y. | 12/4/2010 |
There is a strong expression of both SELPLG and coronin-1C in the majority of primary effusion lymphomas, irrespective of their gene dosage. SELPLG is critical for cell migration and chemotaxis, while CORO1C regulates actin-dependent processes. | Primary effusion lymphoma: genomic profiling revealed amplification of SELPLG and CORO1C encoding for proteins important for cell migration. Luan SL, Boulanger E, Ye H, Chanudet E, Johnson N, Hamoudi RA, Bacon CM, Liu H, Huang Y, Said J, Chu P, Clemen CS, Cesarman E, Chadburn A, Isaacson PG, Du MQ. | 10/23/2010 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Polymorphisms in innate immunity genes and risk of childhood leukemia. Han S, Lan Q, Park AK, Lee KM, Park SK, Ahn HS, Shin HY, Kang HJ, Koo HH, Seo JJ, Choi JE, Ahn YO, Chanock SJ, Kim H, Rothman N, Kang D., Free PMC Article | 06/30/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesRisk of meningioma and common variation in genes related to innate immunity. Rajaraman P, Brenner AV, Neta G, Pfeiffer R, Wang SS, Yeager M, Thomas G, Fine HA, Linet MS, Rothman N, Chanock SJ, Inskip PD. Common variation in genes related to innate immunity and risk of adult glioma. Rajaraman P, Brenner AV, Butler MA, Wang SS, Pfeiffer RM, Ruder AM, Linet MS, Yeager M, Wang Z, Orr N, Fine HA, Kwon D, Thomas G, Rothman N, Inskip PD, Chanock SJ. | 06/30/2010 |
Coronin 1C negatively regulates epithelial cell migration via FAK-mediated inhibition of cell-matrix adhesion. | Coronin 1C negatively regulates cell-matrix adhesion and motility of intestinal epithelial cells. Samarin SN, Koch S, Ivanov AI, Parkos CA, Nusrat A., Free PMC Article | 03/22/2010 |