| New kids on the block: FOS and FOSB gene. | New kids on the block: FOS and FOSB gene.
Cordier F, Creytens D. | 10/28/2023 |
| NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis. | NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis.
López-López S, Romero de Ávila MJ, González-Gómez MJ, Nueda ML, Baladrón V, Monsalve EM, García-Ramírez JJ, Díaz-Guerra MJM. | 10/11/2023 |
| Expression of SARS-CoV-2 receptor angiotensin-converting enzyme 2 by activating protein-1 in human mast cells. | Expression of SARS-CoV-2 receptor angiotensin-converting enzyme 2 by activating protein-1 in human mast cells.
Kim HY, Kang HG, Kim HM, Jeong HJ., Free PMC Article | 04/4/2023 |
| Identifying DUSP-1 and FOSB as hub genes in immunoglobulin A nephropathy by WGCNA and DEG screening and validation. | Identifying DUSP-1 and FOSB as hub genes in immunoglobulin A nephropathy by WGCNA and DEG screening and validation.
Jianping W, Wei X, Li J, Zhang R, Han Q, Yang Q., Free PMC Article | 02/14/2023 |
| Inflammatory lobular hemangioma (T-cell-rich angiomatoid polypoid pseudolymphoma)-Assessment of FOS/FOSB and lymphoid markers and comparison with epithelioid hemangioma. | Inflammatory lobular hemangioma (T-cell-rich angiomatoid polypoid pseudolymphoma)-Assessment of FOS/FOSB and lymphoid markers and comparison with epithelioid hemangioma.
Vargas AC, Maclean FM, Tsu KY, Ma L, Moir D. | 12/10/2022 |
| [The Prognostic Value of FOSB Gene in Acute Myeloid Leukemia]. | [The Prognostic Value of FOSB Gene in Acute Myeloid Leukemia].
Luan SH, Ma YQ, Yang JJ, Wang H, Liu DH, Dou LP. | 08/27/2022 |
| Knockout of FosB gene changes drug sensitivity and invasion activity via the regulation of Bcl-2, E-cadherin, beta-catenin, and vimentin expression. | Knockout of FosB gene changes drug sensitivity and invasion activity via the regulation of Bcl-2, E-cadherin, β-catenin, and vimentin expression.
Na HH, Ryu JM, Kim KC. | 11/22/2021 |
| MicroRNA-27a-3p directly targets FosB to regulate cell proliferation, apoptosis, and inflammation responses in immunoglobulin a nephropathy. | MicroRNA-27a-3p directly targets FosB to regulate cell proliferation, apoptosis, and inflammation responses in immunoglobulin a nephropathy.
Liao Y, Wang Z, Wang L, Lin Y, Ye Z, Zeng X, Wei F. | 02/13/2021 |
| FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner. | FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner.
Du J, Fu L, Ji F, Wang C, Liu S, Qiu X. | 10/24/2020 |
| Clinicopathologic study of 6 cases of epithelioid osteoblastoma of the jaws with immunoexpression analysis of FOS and FOSB. | Clinicopathologic study of 6 cases of epithelioid osteoblastoma of the jaws with immunoexpression analysis of FOS and FOSB.
Pereira TDSF, Andrade BAB, Romañach MJ, Pereira NB, Gomes CC, Mariz BALA, Almeida OP, Agostini M, van Heerden WFP, Carlos R, Gomez RS, Fonseca FP. | 08/29/2020 |
| Association of FOSB exon 4 unmethylation with poor prognosis in patients with latestage nonsmall cell lung cancer. | Association of FOSB exon 4 unmethylation with poor prognosis in patients with late‑stage non‑small cell lung cancer.
Kim DS, Lee WK, Park JY. | 08/22/2020 |
| Poly(ADP-ribose) Polymerases (PARP) cleavage and positive annexin V level are increased during piperlongumine (PL) treatment with FosB overexpression in MCF7 breast cancer cells, whereas PARP cleavage and positive annexin V level were decreased during PL treatment with siFosB transfection, implying that FosB is a pro-apoptotic protein for induction of cell death in PL-treated MCF7 breast cancer cells. | Increased Expression of FosB through Reactive Oxygen Species Accumulation Functions as Pro-Apoptotic Protein in Piperlongumine Treated MCF7 Breast Cancer Cells.
Park JA, Na HH, Jin HO, Kim KC., Free PMC Article | 05/9/2020 |
| Recurrent ACTB-FOSB fusion occurs in pseudomyogenic hemangioendothelioma. | Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma.
Zhu G, Benayed R, Ho C, Mullaney K, Sukhadia P, Rios K, Berry R, Rubin BP, Nafa K, Wang L, Klimstra DS, Ladanyi M, Hameed MR., Free PMC Article | 05/2/2020 |
| We identified increased level of Fos-B mRNA, the binding target of FUS, in FUS-mutant MNs. While Fos-B reduction using si-RNA or an inhibitor ameliorated the observed aberrant axon branching, Fos-B overexpression resulted in aberrant axon branching even in vivo. The commonality of those phenotypes was further confirmed with other amyotrophic lateral sclerosis (ALS) causative mutation than FUS | Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
Akiyama T, Suzuki N, Ishikawa M, Fujimori K, Sone T, Kawada J, Funayama R, Fujishima F, Mitsuzawa S, Ikeda K, Ono H, Shijo T, Osana S, Shirota M, Nakagawa T, Kitajima Y, Nishiyama A, Izumi R, Morimoto S, Okada Y, Kamei T, Nishida M, Nogami M, Kaneda S, Ikeuchi Y, Mitsuhashi H, Nakayama K, Fujii T, Warita H, Okano H, Aoki M., Free PMC Article | 12/21/2019 |
| Recurrent ACTB-FOSB fusions are found in pseudomyogenic hemangioendothelioma. | Expanding the Spectrum of Genetic Alterations in Pseudomyogenic Hemangioendothelioma With Recurrent Novel ACTB-FOSB Gene Fusions.
Agaram NP, Zhang L, Cotzia P, Antonescu CR., Free PMC Article | 09/7/2019 |
| Findings iindicate a human bone tumour defined by mutations of FOS and FOSB. | Recurrent rearrangements of FOS and FOSB define osteoblastoma.
Fittall MW, Mifsud W, Pillay N, Ye H, Strobl AC, Verfaillie A, Demeulemeester J, Zhang L, Berisha F, Tarabichi M, Young MD, Miranda E, Tarpey PS, Tirabosco R, Amary F, Grigoriadis AE, Stratton MR, Van Loo P, Antonescu CR, Campbell PJ, Flanagan AM, Behjati S., Free PMC Article | 12/22/2018 |
| miR-144-3p plays an important role in pancreatic cancer cell proliferation, migration, and invasion by targeting FOSB | miR-144-3p Targets FosB Proto-oncogene, AP-1 Transcription Factor Subunit (FOSB) to Suppress Proliferation, Migration, and Invasion of PANC-1 Pancreatic Cancer Cells.
Liu S, Luan J, Ding Y., Free PMC Article | 10/6/2018 |
| FOSB immunohistochemistry is sensitive in the diagnosis of angiolymphoid hyperplasia with eosinophilia, and allows differentiation from its histological mimics | FOSB immunoreactivity in endothelia of epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia).
Ortins-Pina A, Llamas-Velasco M, Turpin S, Soares-de-Almeida L, Filipe P, Kutzner H. | 10/6/2018 |
| FOSB overexpression results in TNBC cell death, whereas inhibition of calcium signaling eliminates FOSB induction and blocks TP4-induced TNBC cell death | Targeting FOSB with a cationic antimicrobial peptide, TP4, for treatment of triple-negative breast cancer.
Ting CH, Chen YC, Wu CJ, Chen JY., Free PMC Article | 01/20/2018 |
| results shows the involvement of Spry2 in regulation of FosB and Runx2 genes, MAPK signaling and proliferation of mesenchymal stem cells. | Sprouty 2, an Early Response Gene Regulator of FosB and Mesenchymal Stem Cell Proliferation During Mechanical Loading and Osteogenic Differentiation.
Schneider AK, Cama G, Ghuman M, Hughes FJ, Gharibi B. | 12/30/2017 |
| the mechanism underlying redox-regulation of AP-1 Fos/Jun transcription factors and provide structural insight for therapeutic interventions targeting AP-1 proteins. | Activator Protein-1: redox switch controlling structure and DNA-binding.
Yin Z, Machius M, Nestler EJ, Rudenko G., Free PMC Article | 12/2/2017 |
| The NFATc3 first induced the expression of its interaction partner FosB before forming the heterodimeric NFATc3-FosB transcription factor complex, which bound the proximal AP-1 site in the TF gene promoter and activated TF expression. | Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid-induced monocyte trafficking.
Kotla S, Singh NK, Kirchhofer D, Rao GN., Free PMC Article | 09/30/2017 |
| FosB expression in the prefrontal cortex and hippocampus of the cocaine addicted and depression patients | Differential Expression of FosB Proteins and Potential Target Genes in Select Brain Regions of Addiction and Depression Patients.
Gajewski PA, Turecki G, Robison AJ., Free PMC Article | 08/5/2017 |
| FOSB is a highly sensitive and diagnostically useful marker for pseudomyogenic hemangioendothelioma. | FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma.
Hung YP, Fletcher CD, Hornick JL. | 04/29/2017 |
| our findings show that DeltaFosB increases the expression of MMP-9 and exhibits a significantly high survival and proliferation in MCF-7 cells. | Regulatory effects of ΔFosB on proliferation and apoptosis of MCF-7 breast cancer cells.
Li H, Li L, Zheng H, Yao X, Zang W. | 03/11/2017 |