| Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS. | Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.
Vazquez-Sanchez S, Tilkin B, Gasset-Rosa F, Zhang S, Piol D, McAlonis-Downes M, Artates J, Govea-Perez N, Verresen Y, Guo L, Cleveland DW, Shorter J, Da Cruz S., Free PMC Article | 06/25/2024 |
| FUS reads histone H3K36me3 to regulate alternative polyadenylation. | FUS reads histone H3K36me3 to regulate alternative polyadenylation.
Jia J, Fan H, Wan X, Fang Y, Li Z, Tang Y, Zhang Y, Huang J, Fang D., Free PMC Article | 06/11/2024 |
| The crucial role of HFM1 in regulating FUS ubiquitination and localization for oocyte meiosis prophase I progression in mice. | The crucial role of HFM1 in regulating FUS ubiquitination and localization for oocyte meiosis prophase I progression in mice.
Zhong C, Wang H, Yuan X, He Y, Cong J, Yang R, Ma W, Gao L, Gao C, Cui Y, Wu J, Tan R, Pu D., Free PMC Article | 06/7/2024 |
| FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease. | FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease.
Kodavati M, Wang H, Guo W, Mitra J, Hegde PM, Provasek V, Rao VHM, Vedula I, Zhang A, Mitra S, Tomkinson AE, Hamilton DJ, Van Den Bosch L, Hegde ML., Free PMC Article | 03/28/2024 |
| Cytoplasmic retention of the DNA/RNA-binding protein FUS ameliorates organ fibrosis in mice. | Cytoplasmic retention of the DNA/RNA-binding protein FUS ameliorates organ fibrosis in mice.
Chiusa M, Lee YA, Zhang MZ, Harris RC, Sherrill T, Lindner V, Brooks CR, Yu G, Fogo AB, Flynn CR, Zienkiewicz J, Hawiger J, Zent R, Pozzi A., Free PMC Article | 03/19/2024 |
| Aging-disturbed FUS phase transition impairs hematopoietic stem cells by altering chromatin structure. | Aging-disturbed FUS phase transition impairs hematopoietic stem cells by altering chromatin structure.
Tang B, Wang X, He H, Chen R, Qiao G, Yang Y, Xu Z, Wang L, Dong Q, Yu J, Zhang MQ, Shi M, Wang J. | 01/12/2024 |
| CircZNF367 promotes osteoclast differentiation and osteoporosis by interacting with FUS to maintain CRY2 mRNA stability. | CircZNF367 promotes osteoclast differentiation and osteoporosis by interacting with FUS to maintain CRY2 mRNA stability.
Deng M, Wang Z, Luo J, Cao H, Li Y, Chen L, Liu G., Free PMC Article | 07/13/2023 |
| Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes. | Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes.
Tzeplaeff L, Seguin J, Le Gras S, Megat S, Cosquer B, Plassard D, Dieterlé S, Paiva I, Picchiarelli G, Decraene C, Alcala-Vida R, Cassel JC, Merienne K, Dupuis L, Boutillier AL. | 07/12/2023 |
| Brain region-specific synaptic function of FUS underlies the FTLD-linked behavioural disinhibition. | Brain region-specific synaptic function of FUS underlies the FTLD-linked behavioural disinhibition.
Wang JY, Ma GM, Tang XQ, Shi QL, Yu MC, Lou MM, He KW, Wang WY. | 05/5/2023 |
| LncRNA XIST facilitates S1P-mediated osteoclast differentiation via interacting with FUS. | LncRNA XIST facilitates S1P-mediated osteoclast differentiation via interacting with FUS.
Zhang DW, Wang HG, Zhang KB, Guo YQ, Yang LJ, Lv H. | 03/19/2022 |
| Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation. | Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation.
Sanjuan-Ruiz I, Govea-Perez N, McAlonis-Downes M, Dieterle S, Megat S, Dirrig-Grosch S, Picchiarelli G, Piol D, Zhu Q, Myers B, Lee CZ, Cleveland DW, Lagier-Tourenne C, Da Cruz S, Dupuis L., Free PMC Article | 02/5/2022 |
| circGrm1 promotes pulmonary artery smooth muscle cell proliferation and migration via suppression of GRM1 expression by FUS. | circ‑Grm1 promotes pulmonary artery smooth muscle cell proliferation and migration via suppression of GRM1 expression by FUS.
Sun S, Kong Q, Cai Z, Wang M, Zhao H, Zhao C., Free PMC Article | 01/29/2022 |
| FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development. | FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development.
Chioccarelli T, Falco G, Cappetta D, De Angelis A, Roberto L, Addeo M, Ragusa M, Barbagallo D, Berrino L, Purrello M, Ambrosino C, Cobellis G, Pierantoni R, Chianese R, Manfrevola F., Free PMC Article | 01/22/2022 |
| ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity. | ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity.
Garone MG, Birsa N, Rosito M, Salaris F, Mochi M, de Turris V, Nair RR, Cunningham TJ, Fisher EMC, Morlando M, Fratta P, Rosa A., Free PMC Article | 12/11/2021 |
| Conditional depletion of Fus in oligodendrocytes leads to motor hyperactivity and increased myelin deposition associated with Akt and cholesterol activation. | Conditional depletion of Fus in oligodendrocytes leads to motor hyperactivity and increased myelin deposition associated with Akt and cholesterol activation.
Guzman KM, Brink LE, Rodriguez-Bey G, Bodnar RJ, Kuang L, Xing B, Sullivan M, Park HJ, Koppes E, Zhu H, Padiath Q, Cambi F., Free PMC Article | 11/13/2021 |
| FUS-dependent loading of SUV39H1 to OCT4 pseudogene-lncRNA programs a silencing complex with OCT4 promoter specificity. | FUS-dependent loading of SUV39H1 to OCT4 pseudogene-lncRNA programs a silencing complex with OCT4 promoter specificity.
Scarola M, Comisso E, Rosso M, Del Sal G, Schneider C, Schoeftner S, Benetti R., Free PMC Article | 07/3/2021 |
| FUS regulates autophagy by mediating the transcription of genes critical to the autophagosome formation. | FUS regulates autophagy by mediating the transcription of genes critical to the autophagosome formation.
Arenas A, Kuang L, Zhang J, Kingren MS, Zhu H., Free PMC Article | 06/26/2021 |
| FUS/TLS Suppresses Enterovirus Replication and Promotes Antiviral Innate Immune Responses. | FUS/TLS Suppresses Enterovirus Replication and Promotes Antiviral Innate Immune Responses.
Xue YC, Ng CS, Mohamud Y, Fung G, Liu H, Bahreyni A, Zhang J, Luo H., Free PMC Article | 06/19/2021 |
| Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS. | Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS.
Sahadevan S, Hembach KM, Tantardini E, Pérez-Berlanga M, Hruska-Plochan M, Megat S, Weber J, Schwarz P, Dupuis L, Robinson MD, De Rossi P, Polymenidou M., Free PMC Article | 06/12/2021 |
| Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects. | Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Scekic-Zahirovic J, Sanjuan-Ruiz I, Kan V, Megat S, De Rossi P, Dieterlé S, Cassel R, Jamet M, Kessler P, Wiesner D, Tzeplaeff L, Demais V, Sahadevan S, Hembach KM, Muller HP, Picchiarelli G, Mishra N, Antonucci S, Dirrig-Grosch S, Kassubek J, Rasche V, Ludolph A, Boutillier AL, Roselli F, Polymenidou M, Lagier-Tourenne C, Liebscher S, Dupuis L., Free PMC Article | 06/12/2021 |
| Molecular and behavioural abnormalities in the FUS-tg mice mimic frontotemporal lobar degeneration: Effects of old and new anti-inflammatory therapies. | Molecular and behavioural abnormalities in the FUS-tg mice mimic frontotemporal lobar degeneration: Effects of old and new anti-inflammatory therapies.
de Munter J, Babaevskaya D, Wolters EC, Pavlov D, Lysikova E, V Kalueff A, Gorlova A, Oplatchikova M, Pomytkin IA, Proshin A, Umriukhin A, Lesch KP, Strekalova T., Free PMC Article | 05/8/2021 |
| Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes. | Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.
Sleigh JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K, Schiavo G., Free PMC Article | 03/27/2021 |
| Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis. | Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Jutzi D, Campagne S, Schmidt R, Reber S, Mechtersheimer J, Gypas F, Schweingruber C, Colombo M, von Schroetter C, Loughlin FE, Devoy A, Hedlund E, Zavolan M, Allain FH, Ruepp MD., Free PMC Article | 01/9/2021 |
| LncRNA KCNQ1OT1 contributes to cardiomyocyte apoptosis by targeting FUS in heart failure. | LncRNA KCNQ1OT1 contributes to cardiomyocyte apoptosis by targeting FUS in heart failure.
Lai L, Xu Y, Kang L, Yang J, Zhu G. | 10/31/2020 |
| FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention. | FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Humphrey J, Birsa N, Milioto C, McLaughlin M, Ule AM, Robaldo D, Eberle AB, Kräuchi R, Bentham M, Brown AL, Jarvis S, Bodo C, Garone MG, Devoy A, Soraru G, Rosa A, Bozzoni I, Fisher EMC, Mühlemann O, Schiavo G, Ruepp MD, Isaacs AM, Plagnol V, Fratta P., Free PMC Article | 09/12/2020 |