| Mutations in the NUP93, NUP107 and NUP160 genes cause steroid-resistant nephrotic syndrome in Chinese children. | Mutations in the NUP93, NUP107 and NUP160 genes cause steroid-resistant nephrotic syndrome in Chinese children.
Han Y, Sha H, Yang Y, Yu Z, Zhou L, Wang Y, Yang F, Qiu L, Zhang Y, Zhou J., Free PMC Article | 06/30/2024 |
| Role and Mechanism of NUP160-regulated Autophagy in Pathogenesis of Diabetic Nephropathy. | Role and Mechanism of NUP160-regulated Autophagy in Pathogenesis of Diabetic Nephropathy.
Xie J, Yuan Y, Yao G, Yu W, Zhu Q. | 12/6/2023 |
| Nup107-160 complex and its partner Elys dynamically colocalize with Nup98 and CRM1 into endogenous GLFG bodies present in specific HeLa sublines. | Intranuclear dynamics of the Nup107-160 complex.
Morchoisne-Bolhy S, Geoffroy MC, Bouhlel IB, Alves A, Audugé N, Baudin X, Van Bortle K, Powers MA, Doye V., Free PMC Article | 05/21/2016 |
| transcriptome sequencing of patient-derived angiosarcoma cells, identified a novel fusion gene NUP160-SLC43A3 found to be expressed in 9 of 25 human angiosarcoma specimens that were examined. | NUP160-SLC43A3 is a novel recurrent fusion oncogene in angiosarcoma.
Shimozono N, Jinnin M, Masuzawa M, Masuzawa M, Wang Z, Hirano A, Tomizawa Y, Etoh-Kira T, Kajihara I, Harada M, Fukushima S, Ihn H. | 02/27/2016 |
| The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex. | The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex.
Goeres J, Chan PK, Mukhopadhyay D, Zhang H, Raught B, Matunis MJ., Free PMC Article | 08/4/2012 |
| The interactions of Nup160 with Pom121 and are predicted to assist in the formation of the nuclear pore and the anchoring of the Nuclear pore complexes to the pore membrane. | Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane.
Mitchell JM, Mansfeld J, Capitanio J, Kutay U, Wozniak RW., Free PMC Article | 12/11/2010 |
| A major function of the Nup107 complex in mitosis is to ensure the proper localization of the chromosome passenger complex at the centromere. | The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex.
Platani M, Santarella-Mellwig R, Posch M, Walczak R, Swedlow JR, Mattaj IW., Free PMC Article | 03/15/2010 |
| Data show that Nup107-160 promotes spindle assembly through Ran-GTP-regulated nucleation of microtubules by gamma-TuRC at kinetochores, and reveal a relationship between nucleoporins and the microtubule cytoskeleton. | The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores.
Mishra RK, Chakraborty P, Arnaoutov A, Fontoura BM, Dasso M., Free PMC Article | 03/1/2010 |
| Data show that structure-guided sequence comparison of Nup160 and Saccharomyces cerevisiae Nup120 strongly suggests that both proteins adopt the same unique fold despite a low sequence identity of 10%. | The structure of the scaffold nucleoporin Nup120 reveals a new and unexpected domain architecture.
Leksa NC, Brohawn SG, Schwartz TU., Free PMC Article | 02/22/2010 |
| These data thus provide the first molecular clues underlying the function of the human Nup107-160 complex at kinetochores. | The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.
Zuccolo M, Alves A, Galy V, Bolhy S, Formstecher E, Racine V, Sibarita JB, Fukagawa T, Shiekhattar R, Yen T, Doye V., Free PMC Article | 01/21/2010 |
| Nup107-160 complex is dynamic in mitosis and that it promotes spindle assembly in a manner that is distinct from its functions at interphase nuclear pores. | The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.
Orjalo AV, Arnaoutov A, Shen Z, Boyarchuk Y, Zeitlin SG, Fontoura B, Briggs S, Dasso M, Forbes DJ., Free PMC Article | 01/21/2010 |
| phosphorylation does not affect interactions within the Nup107-160 subcomplex, but regulates the association of the subcomplex with the NPC and other proteins | Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.
Glavy JS, Krutchinsky AN, Cristea IM, Berke IC, Boehmer T, Blobel G, Chait BT., Free PMC Article | 01/21/2010 |