| YAP represses intestinal inflammation through epigenetic silencing of JMJD3. | YAP represses intestinal inflammation through epigenetic silencing of JMJD3.
Zhu H, Lu J, Fu M, Chen P, Yu Y, Chen M, Zhao Q, Wu M, Ye M., Free PMC Article | 02/1/2024 |
| MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B. | MicroRNA-93-5p regulates odontogenic differentiation and dentin formation via KDM6B.
Wu S, Xu X, Gao S, Huo S, Wan M, Zhou X, Zhou X, Zheng L, Zhou Y., Free PMC Article | 01/17/2024 |
| Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models. | Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models.
Ge G, Zhang P, Sui P, Chen S, Yang H, Guo Y, Rubalcava IP, Noor A, Delma CR, Agosto-Peña J, Geng H, Medina EA, Liang Y, Nimer SD, Mesa R, Abdel-Wahab O, Xu M, Yang FC., Free PMC Article | 01/8/2024 |
| The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study. | The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study.
Yu S, Guo J, Yang D, Yan X, Zhang Z, Wei P, Qiu L. | 12/26/2023 |
| KDM6B drives epigenetic reprogramming associated with lymphoid stromal cell early commitment and immune properties. | KDM6B drives epigenetic reprogramming associated with lymphoid stromal cell early commitment and immune properties.
Sylvestre M, Barbier N, Sibut V, Nayar S, Monvoisin C, Leonard S, Saint-Vanne J, Martin A, Guirriec M, Latour M, Jouan F, Baulande S, Bohec M, Verdière L, Mechta-Grigoriou F, Mourcin F, Bertheuil N, Barone F, Tarte K, Roulois D., Free PMC Article | 12/4/2023 |
| Echinococcus granulosus cyst fluid inhibits KDM6B-mediated demethylation of trimethylated histone H3 lysine 27 and interleukin-1beta production in macrophages. | Echinococcus granulosus cyst fluid inhibits KDM6B-mediated demethylation of trimethylated histone H3 lysine 27 and interleukin-1β production in macrophages.
Lin R, Wang X, Ni C, Fu C, Yang C, Dong D, Wu X, Chen X, Wang L, Hou J., Free PMC Article | 11/28/2023 |
| Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade. | Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade.
Goswami S, Raychaudhuri D, Singh P, Natarajan SM, Chen Y, Poon C, Hennessey M, Tannir AJ, Zhang J, Anandhan S, Kerrigan BP, Macaluso MD, He Z, Jindal S, Lang FF, Basu S, Sharma P. | 10/30/2023 |
| NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis. | NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis.
López-López S, Romero de Ávila MJ, González-Gómez MJ, Nueda ML, Baladrón V, Monsalve EM, García-Ramírez JJ, Díaz-Guerra MJM. | 10/11/2023 |
| Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease-related HCC. | Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease-related HCC.
Hatano M, Akiyama Y, Shimada S, Yagi K, Akahoshi K, Itoh M, Tanabe M, Ogawa Y, Tanaka S., Free PMC Article | 10/5/2023 |
| JMJD3 is Involved in Intracranial Aneurysm Development by Regulating DLX2 Expression through H3K27me3 Modification. | JMJD3 is Involved in Intracranial Aneurysm Development by Regulating DLX2 Expression through H3K27me3 Modification.
Wang X, Li N, Li T. | 09/25/2023 |
| Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3. | Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3.
Kobori C, Takagi R, Yokomizo R, Yoshihara S, Mori M, Takahashi H, Javaregowda PK, Akiyama T, Ko MSH, Kishi K, Umezawa A., Free PMC Article | 09/14/2023 |
| E2F1-driven histone demethylase KDM6B enhances thyroid malignancy via manipulating TFEB-dependent autophagy axis. | E2F1-driven histone demethylase KDM6B enhances thyroid malignancy via manipulating TFEB-dependent autophagy axis.
Wang X, Zhang C, Dong N, Xu H, Zhou Y, Hou D. | 09/11/2023 |
| KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress. | KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress.
Issa N, Bjeije H, Wilson ER, Krishnan A, Dunuwille WMB, Parsons TM, Zhang CR, Han W, Young AL, Ren Z, Ge K, Wang ES, Weng AP, Cashen A, Spencer DH, Challen GA., Free PMC Article | 04/12/2023 |
| Aberrant expression of JMJD3 in SLE promotes B-cell differentiation. | Aberrant expression of JMJD3 in SLE promotes B-cell differentiation.
Mei Y, Xin Y, Li X, Yin H, Xiong F, Yang M, Wu H. | 03/7/2023 |
| KDM6B promotes gastric carcinogenesis and metastasis via upregulation of CXCR4 expression. | KDM6B promotes gastric carcinogenesis and metastasis via upregulation of CXCR4 expression.
Liu F, Wang Y, Yang Z, Cui X, Zheng L, Fu Y, Shao W, Zhang L, Yang Q, Jia J., Free PMC Article | 01/11/2023 |
| KDM6B regulates M2 polarization of macrophages by modulating the stability of nuclear beta-catenin. | KDM6B regulates M2 polarization of macrophages by modulating the stability of nuclear β-catenin.
Du L, Dai B, Liu X, Zhou D, Yan H, Shen T, Wang D, Tan X. | 12/31/2022 |
| A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates. | A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates.
Lesbon JCC, Garnica TK, Xavier PLP, Rochetti AL, Reis RM, Müller S, Fukumasu H., Free PMC Article | 10/22/2022 |
| Decreased Jumonji Domain-Containing 3 at the Promoter Downregulates Hematopoietic Progenitor Kinase 1 Expression and Cytoactivity of T Follicular Helper Cells from Systemic Lupus Erythematosus Patients. | Decreased Jumonji Domain-Containing 3 at the Promoter Downregulates Hematopoietic Progenitor Kinase 1 Expression and Cytoactivity of T Follicular Helper Cells from Systemic Lupus Erythematosus Patients.
Luo S, Xie Y, Huang J, Liu J, Zhang Q., Free PMC Article | 10/22/2022 |
| JMJD3 Promotes Porphyromonas gingivalis Lipopolysaccharide-Induced Th17-Cell Differentiation by Modulating the STAT3-RORc Signaling Pathway. | JMJD3 Promotes Porphyromonas gingivalis Lipopolysaccharide-Induced Th17-Cell Differentiation by Modulating the STAT3-RORc Signaling Pathway.
Huang D, Zhang C, Wang P, Li X, Gao L, Zhao C., Free PMC Article | 08/20/2022 |
| Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia. | Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia.
Wei Y, Kanagal-Shamanna R, Zheng H, Bao N, Lockyer PP, Class CA, Darbaniyan F, Lu Y, Lin K, Yang H, Montalban-Bravo G, Ganan-Gomez I, Soltysiak KA, Do KA, Colla S, Garcia-Manero G. | 08/13/2022 |
| Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1. | Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1.
Jin Y, Liu Z, Li Z, Li H, Zhu C, Li R, Zhou T, Fang B., Free PMC Article | 07/23/2022 |
| Histone Demethylase Jmjd3 Regulates the Osteogenic Differentiation and Cytokine Expressions of Periodontal Ligament Cells. | Histone Demethylase Jmjd3 Regulates the Osteogenic Differentiation and Cytokine Expressions of Periodontal Ligament Cells.
Yu B, Wang R, Luo H, Yang D, Wang S, Yu Y, Okamura H, Qiu L. | 07/9/2022 |
| Jumonji Domain-containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility. | Jumonji Domain-containing Protein-3 (JMJD3/Kdm6b) Is Critical for Normal Ovarian Function and Female Fertility.
Roy S, Sinha N, Huang B, Cline-Fedewa H, Gleicher N, Wang J, Sen A., Free PMC Article | 05/14/2022 |
| The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells. | The Epigenetic Regulation of OLIG2 by Histone Demethylase KDM6B in Glioma Cells.
Sui A, Han B, Ren W, He W, Gao C, Han X, Liu S, Zhang Y, Qi X, Guo X. | 05/7/2022 |
| Lysine Demethylase 6B Regulates Prostate Cancer Cell Proliferation by Controlling c-MYC Expression. | Lysine Demethylase 6B Regulates Prostate Cancer Cell Proliferation by Controlling c-MYC Expression.
Yıldırım-Buharalıoğlu G. | 03/5/2022 |