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    FOXO1 forkhead box O1 [ Homo sapiens (human) ]

    Gene ID: 2308, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Inhibition of the FOXO1-ROCK1 axis mitigates cardiomyocyte injury under chronic hypoxia in Tetralogy of Fallot by maintaining mitochondrial quality control.

    Inhibition of the FOXO1-ROCK1 axis mitigates cardiomyocyte injury under chronic hypoxia in Tetralogy of Fallot by maintaining mitochondrial quality control.
    Ren C, Xi L, Li H, Pan Z, Li Y, Wang G, Dai J, He D, Fan S, Wang Q.

    10/25/2024
    miR-132-3p downregulates FOXO1 in CD4[+] T cells and is associated with disease manifestations in patients with lupus.

    miR-132-3p downregulates FOXO1 in CD4(+) T cells and is associated with disease manifestations in patients with lupus.
    Qin H, Chen S, Liu X, Liang J, Wu H, Zhu X., Free PMC Article

    10/22/2024
    FOXO1 induced fatty acid oxidation in hepatic cells by targeting ALDH1L2.

    FOXO1 induced fatty acid oxidation in hepatic cells by targeting ALDH1L2.
    Cheng J, Yang S, Shou D, Chen J, Li Y, Huang C, Chen H, Zhou Y.

    10/17/2024
    Circular RNA circMRPS35 represses malignant progression in osteosarcoma cells via targeting miR-105-5p/FOXO1.

    Circular RNA circMRPS35 represses malignant progression in osteosarcoma cells via targeting miR-105-5p/FOXO1.
    Jiang C, Jiang Z, Zhang X., Free PMC Article

    10/1/2024
    STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma.

    STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma.
    Zhao Z, Chu Y, Feng A, Zhang S, Wu H, Li Z, Sun M, Zhang L, Chen T, Xu M., Free PMC Article

    09/25/2024
    The roles of stress-induced premature senescence and Akt/FoxO1 signaling in periapical lesions.

    The roles of stress-induced premature senescence and Akt/FoxO1 signaling in periapical lesions.
    Liu Q, Li S, Tang T, Wu Y.

    09/24/2024
    Forkhead box O1 transcription factor; a therapeutic target for diabetic cardiomyopathy.

    Forkhead box O1 transcription factor; a therapeutic target for diabetic cardiomyopathy.
    Shafaati T, Gopal K., Free PMC Article

    09/11/2024
    SIRT1 silencing ameliorates malignancy of non-small cell lung cancer via activating FOXO1.

    SIRT1 silencing ameliorates malignancy of non-small cell lung cancer via activating FOXO1.
    Chen J, Chen K, Zhang S, Huang X., Free PMC Article

    09/10/2024
    CircGNAO1 suppresses hepatocellular carcinoma progression and metastasis via sponging miR-182-5p and regulating FOXO1 expression.

    CircGNAO1 suppresses hepatocellular carcinoma progression and metastasis via sponging miR-182-5p and regulating FOXO1 expression.
    Ju L, Luo Y, Shan J, Lu R, Chen L, Shao J, Bian Z, Yao M.

    09/9/2024
    FoxO1-Overexpressed Small Extracellular Vesicles Derived from hPDLSCs Promote Periodontal Tissue Regeneration by Reducing Mitochondrial Dysfunction to Regulate Osteogenesis and Inflammation.

    FoxO1-Overexpressed Small Extracellular Vesicles Derived from hPDLSCs Promote Periodontal Tissue Regeneration by Reducing Mitochondrial Dysfunction to Regulate Osteogenesis and Inflammation.
    Niu Q, Lin C, Yang S, Rong S, Wei J, Zhao T, Peng Y, Cheng Z, Xie Y, Wang Y., Free PMC Article

    09/4/2024
    Identification of FOXO1 as a geroprotector in human synovium through single-nucleus transcriptomic profiling.

    Identification of FOXO1 as a geroprotector in human synovium through single-nucleus transcriptomic profiling.
    Liu F, Lu Y, Wang X, Sun S, Pan H, Wang M, Wang Z, Zhang W, Ma S, Sun G, Chu Q, Wang S, Qu J, Liu GH., Free PMC Article

    08/22/2024
    Cancer-associated fibroblasts promote the malignant development of lung cancer through the FOXO1 protein/LIF signaling.

    Cancer-associated fibroblasts promote the malignant development of lung cancer through the FOXO1 protein/LIF signaling.
    Shen J, Wu W, Zhang X, Xie X, Shen W, Wang Q.

    08/21/2024
    FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.

    FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease.
    Jiang C, Yao D, Liu Z, Zheng Y, Chen M, Yim WY, Zheng Q, Zhang T, Fan L, Fan Z, Geng B, Tian R, Zhou T, Qiao W, Shi J, Li F, Xu L, Huang Y, Dong N., Free PMC Article

    06/25/2024
    NEK2 promotes the development of ovarian endometriosis and impairs decidualization by phosphorylating FOXO1.

    NEK2 promotes the development of ovarian endometriosis and impairs decidualization by phosphorylating FOXO1.
    Wang M, Sun F, Zhang S, Zhang X, Sun Y, Yu T, Li Y, Jiang A, Qiao P, Ren C, Yang T., Free PMC Article

    06/3/2024
    Silencing FUT4 Inhibits the Progression of Osteosarcoma through Activation of FOXO1.

    Silencing FUT4 Inhibits the Progression of Osteosarcoma through Activation of FOXO1.
    Yang Y, Yan X, Chen Y, Liu J, Xue J, Sheng X, Qin J, Xue Q, Liu X., Free PMC Article

    06/3/2024
    BMP4 in Human Endometrial Stromal Cells Can Affect Decidualization by Regulating FOXO1 Expression.

    BMP4 in Human Endometrial Stromal Cells Can Affect Decidualization by Regulating FOXO1 Expression.
    Huang Y, Dai F, Chen L, Li Z, Liu H, Cheng Y.

    06/3/2024
    FOXO1 regulates wound-healing responses in human gingival fibroblasts.

    FOXO1 regulates wound-healing responses in human gingival fibroblasts.
    Rojas L, Tobar N, Espinoza J, Ríos S, Martínez C, Martínez J, Graves DT, Smith PC.,

    05/31/2024
    FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation.

    FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation.
    Tomiyasu H, Habara M, Hanaki S, Sato Y, Miki Y, Shimada M., Free PMC Article

    05/20/2024
    An extensive analysis of the prognostic and immune role of FOXO1 in various types of cancer.

    An extensive analysis of the prognostic and immune role of FOXO1 in various types of cancer.
    Li J, Wang C, Xu X, Chen J, Guo H., Free PMC Article

    05/13/2024
    FoxO1 promotes ovarian cancer by increasing transcription and METTL14-mediated m[6]A modification of SMC4.

    FoxO1 promotes ovarian cancer by increasing transcription and METTL14-mediated m(6)A modification of SMC4.
    Tan L, Wang S, Huang S, Tie Y, Sai N, Mao Y, Zhao S, Hou Y, Dou H., Free PMC Article

    04/24/2024
    Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1.

    Homeobox B2 promotes malignant behavior and contributes to the radioresistance of nasopharyngeal carcinoma by regulating forkhead box protein O1.
    Chen J, Mao M, Ma Z, Liu J, Jiang M, Chen G, Xu Y., Free PMC Article

    04/18/2024
    The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5-fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway.

    The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5-fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway.
    Han A, Liu T, Du P, Wang M, Liu J, Chen L.

    03/15/2024
    Human Amniotic MSC Response in LPS-Stimulated Ascites from Patients with Cirrhosis: FOXO1 Gene and Th17 Activation in Enhanced Antibacterial Activation.

    Human Amniotic MSC Response in LPS-Stimulated Ascites from Patients with Cirrhosis: FOXO1 Gene and Th17 Activation in Enhanced Antibacterial Activation.
    Pampalone M, Cuscino N, Iannolo G, Amico G, Ricordi C, Vitale G, Carcione C, Castelbuono S, Scilabra SD, Coronnello C, Gruttadauria S, Pietrosi G., Free PMC Article

    03/14/2024
    Brg1/PRMT5 nuclear complex epigenetically regulates FOXO1 in IPF mesenchymal progenitor cells.

    Brg1/PRMT5 nuclear complex epigenetically regulates FOXO1 in IPF mesenchymal progenitor cells.
    Jbeli AH, Yang L, Xia H, Gilbertsen AJ, Bitterman PB, Henke CA.,

    03/7/2024
    The Roles and Regulatory Mechanisms of Tight Junction Protein Cingulin and Transcription Factor Forkhead Box Protein O1 in Human Lung Adenocarcinoma A549 Cells and Normal Lung Epithelial Cells.

    The Roles and Regulatory Mechanisms of Tight Junction Protein Cingulin and Transcription Factor Forkhead Box Protein O1 in Human Lung Adenocarcinoma A549 Cells and Normal Lung Epithelial Cells.
    Ishii D, Shindo Y, Arai W, Konno T, Kohno T, Honda K, Miyajima M, Watanabe A, Kojima T., Free PMC Article

    02/27/2024
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