| Formin Binding Protein 1 (FNBP1) regulates non-canonical Wnt signaling and vertebrate gastrulation. | Formin Binding Protein 1 (FNBP1) regulates non-canonical Wnt signaling and vertebrate gastrulation.
Zeni C, Komiya Y, Habas R., | 08/12/2024 |
| The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis. | The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis.
Phillips AT, Boumil EF, Venkatesan A, Tilstra-Smith C, Castro N, Knox BE, Henty-Ridilla JL, Bernstein AM., Free PMC Article | 12/1/2023 |
| Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression. | Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression.
Chen A, Liu Z, Wu Q, Li H. | 02/26/2022 |
| Preliminary Investigation on the Involvement of Cytoskeleton-Related Proteins, DAAM1 and PREP, in Human Testicular Disorders. | Preliminary Investigation on the Involvement of Cytoskeleton-Related Proteins, DAAM1 and PREP, in Human Testicular Disorders.
Venditti M, Arcaniolo D, De Sio M, Minucci S., Free PMC Article | 09/18/2021 |
| SNHG15 facilitated malignant behaviors of oral squamous cell carcinoma through targeting miR-188-5p/DAAM1. | SNHG15 facilitated malignant behaviors of oral squamous cell carcinoma through targeting miR-188-5p/DAAM1.
Wang T, Liang D, Yang H. | 09/4/2021 |
| Dishevelled Associated Activator Of Morphogenesis (DAAM) Facilitates Invasion of Hepatocellular Carcinoma by Upregulating Hypoxia-Inducible Factor 1alpha (HIF-1alpha) Expression. | Dishevelled Associated Activator Of Morphogenesis (DAAM) Facilitates Invasion of Hepatocellular Carcinoma by Upregulating Hypoxia-Inducible Factor 1α (HIF-1α) Expression.
Fang X, Zhang D, Zhao W, Gao L, Wang L., Free PMC Article | 06/12/2021 |
| DAAM1 and PREP are involved in human spermatogenesis. | DAAM1 and PREP are involved in human spermatogenesis.
Venditti M, Fasano C, Minucci S, Serino I, Sinisi AA, Dale B, Di Matteo L. | 01/16/2021 |
| Overexpressed DAAM1 correlates with metastasis and predicts poor prognosis in breast cancer. | Overexpressed DAAM1 correlates with metastasis and predicts poor prognosis in breast cancer.
Mei J, Xu B, Hao L, Xiao Z, Liu Y, Yan T, Zhu Y. | 11/21/2020 |
| Wnt5a/ROR1 activates DAAM1 and promotes the migration in osteosarcoma cells. | Wnt5a/ROR1 activates DAAM1 and promotes the migration in osteosarcoma cells.
Dai B, Shen Y, Yan T, Zhang A. | 08/22/2020 |
| findings reveal a novel mechanism by which reversible tyrosine phosphorylation of DAAM1 by Src and PTPN3 regulates actin dynamics and lung cancer invasivenes | PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization.
Li MY, Peng WH, Wu CH, Chang YM, Lin YL, Chang GD, Wu HC, Chen GC. | 02/29/2020 |
| Our data suggest that miR-208-5p/DAAM1 axis participates in ovarian cancer migration and invasion. | DAAM1-mediated migration and invasion of ovarian cancer cells are suppressed by miR-208a-5p.
Mei J, Huang Y, Hao L, Liu Y, Yan T, Qiu T, Xu R, Xu B, Xiao Z, Jiang X, Hu K, Zhu Y. | 01/18/2020 |
| miR-613 is involved in cell migration and invasion of triple-negative breast cancer cells via targeting Daam1/RhoA signaling pathway. | miR-613 inhibits cell migration and invasion by downregulating Daam1 in triple-negative breast cancer.
Xiong H, Yan T, Zhang W, Shi F, Jiang X, Wang X, Li S, Chen Y, Chen C, Zhu Y. | 06/29/2019 |
| Integrin alphavbeta3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells | Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
Yan T, Zhang A, Shi F, Chang F, Mei J, Liu Y, Zhu Y., Free PMC Article | 01/19/2019 |
| coiling phagocytosis is a mechanism for borrelial internalization by neuroglial cells mediated by Daam1 | Human neuroglial cells internalize Borrelia burgdorferi by coiling phagocytosis mediated by Daam1.
Williams SK, Weiner ZP, Gilmore RD., Free PMC Article | 12/22/2018 |
| Results provide evidence that Daam1 activates RhoA to regulate Wnt5ainduced glioblastoma cell invasion. | Daam1 activates RhoA to regulate Wnt5a‑induced glioblastoma cell invasion.
Liu G, Yan T, Li X, Sun J, Zhang B, Wang H, Zhu Y., Free PMC Article | 09/8/2018 |
| DAAM1 organizes actin filaments into a nodal complex | Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network.
Luo W, Lieu ZZ, Manser E, Bershadsky AD, Sheetz MP., Free PMC Article | 06/10/2017 |
| Kank1 plays a crucial role in regulating the activity of RhoA through retrieving excess Daam1 and balancing the activities of RhoA and its effectors. | Depletion of tumor suppressor Kank1 induces centrosomal amplification via hyperactivation of RhoA.
Suzuki JI, Roy BC, Ogaeri T, Kakinuma N, Kiyama R. | 05/27/2017 |
| High Daam-1 expression may upregulate the Wnt/PCP pathway and cause idiopathic pulmonary arterial hypertension | Implication of overexpression of dishevelled-associated activator of morphogenesis 1 (Daam-1) for the pathogenesis of human Idiopathic Pulmonary Arterial Hypertension (IPAH).
Yanai S, Wakayama M, Nakayama H, Shinozaki M, Tsukuma H, Tochigi N, Nemoto T, Saji T, Shibuya K., Free PMC Article | 03/18/2017 |
| Kif26b, together with Dvl3/Daam1, initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells. | Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway.
Guillabert-Gourgues A, Jaspard-Vinassa B, Bats ML, Sewduth RN, Franzl N, Peghaire C, Jeanningros S, Moreau C, Roux E, Larrieu-Lahargue F, Dufourcq P, Couffinhal T, Duplàa C., Free PMC Article | 01/14/2017 |
| Daam1 plays a dual role in the phagocytic uptake of borreliae. | Daam1 is a regulator of filopodia formation and phagocytic uptake of Borrelia burgdorferi by primary human macrophages.
Hoffmann AK, Naj X, Linder S. | 09/27/2014 |
| A developmentally restricted function of miR-490 and its putative DAAM1 target are associated with exaggerated megakaryocytopoiesis and/or proplatelet formation. | Systematic analysis of microRNA fingerprints in thrombocythemic platelets using integrated platforms.
Xu X, Gnatenko DV, Ju J, Hitchcock IS, Martin DW, Zhu W, Bahou WF., Free PMC Article | 01/5/2013 |
| Wnt5a promotes breast cancer cell migration via Dvl2/Daam1/RhoA. | Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.
Zhu Y, Tian Y, Du J, Hu Z, Yang L, Liu J, Gu L., Free PMC Article | 09/29/2012 |
| DAAM1 is a formin required for centrosome re-orientation during cell migration. | DAAM1 is a formin required for centrosome re-orientation during cell migration.
Ang SF, Zhao ZS, Lim L, Manser E., Free PMC Article | 02/26/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Fli-I promotes the GTP-bound active Rho-mediated relief of the autoinhibition of Daam1 and mDia1. Thus, Fli-I is a novel positive regulator of Rho-induced linear actin assembly mediated by DRFs. | Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase.
Higashi T, Ikeda T, Murakami T, Shirakawa R, Kawato M, Okawa K, Furuse M, Kimura T, Kita T, Horiuchi H., Free PMC Article | 06/28/2010 |