| SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner. | SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner.
Geng A, Sun J, Tang H, Yu Y, Wang X, Zhang J, Wang X, Sun X, Zhou X, Gao N, Tan R, Xu Z, Jiang Y, Mao Z., Free PMC Article | 06/10/2024 |
| Biophysical insights into the dimer formation of human Sirtuin 2. | Biophysical insights into the dimer formation of human Sirtuin 2.
Suzuki N, Konuma T, Ikegami T, Akashi S., | 05/7/2024 |
| Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice. | Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B. | 03/29/2024 |
| Construction of a prediction model for postoperative prognosis in patients with resectable cholangiocarcinoma based on silence information regulator 2 expression. | Construction of a prediction model for postoperative prognosis in patients with resectable cholangiocarcinoma based on silence information regulator 2 expression.
Wang W, Ji W, Lyu Z, Sun W, Shao Y, Liu J, Yang Y., Free PMC Article | 03/4/2024 |
| KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2. | KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2.
Bai Q, Jin W, Chen F, Zhu J, Cao L, Yang Y, Zhong F, Li L. | 03/1/2024 |
| FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation. | FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation.
Chen K, Wang Y, Dai X, Luo J, Hu S, Zhou Z, Shi J, Pan X, Cao T, Xia J, Li Y, Wang Z, Ma J., Free PMC Article | 02/6/2024 |
| Decoding the multifaceted interventions between human sirtuin 2 and dynamic hepatitis B viral proteins to confirm their roles in HBV replication. | Decoding the multifaceted interventions between human sirtuin 2 and dynamic hepatitis B viral proteins to confirm their roles in HBV replication.
Piracha ZZ, Saeed U, Piracha IE, Noor S, Noor E., Free PMC Article | 01/31/2024 |
| Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma. | Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma.
Malgulwar PB, Danussi C, Dharmaiah S, Johnson W, Singh A, Rai K, Rao A, Huse JT., | 01/9/2024 |
| Sirtuin 2 promotes human cytomegalovirus replication by regulating cell cycle progression. | Sirtuin 2 promotes human cytomegalovirus replication by regulating cell cycle progression.
Betsinger CN, Justice JL, Tyl MD, Edgar JE, Budayeva HG, Abu YF, Cristea IM., Free PMC Article | 01/6/2024 |
| Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis. | Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis.
Zhao Q, Xia N, Xu J, Wang Y, Feng L, Su D, Cheng Z., Free PMC Article | 01/4/2024 |
| Effects of Dimerization on the Deacylase Activities of Human SIRT2. | Effects of Dimerization on the Deacylase Activities of Human SIRT2.
Yang J, Nicely NI, Weiser BP., Free PMC Article | 12/20/2023 |
| SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells. | SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells.
Yang S, Yang G, Wang X, Xiang J, Kang L, Liang Z., Free PMC Article | 10/13/2023 |
| Paraneoplastic or not? Sirtuin 2 in anti-N-methyl-d-aspartate receptor encephalitis. | Paraneoplastic or not? Sirtuin 2 in anti-N-methyl-d-aspartate receptor encephalitis.
Stevens-Jones O, Mojzisova H, Elisak M, Constantinescu R, Hanzalova J, Axelsson M, Krysl D. | 09/12/2023 |
| Inhibition of SIRT2 promotes death of human cytomegalovirus-infected peripheral blood monocytes via apoptosis and necroptosis. | Inhibition of SIRT2 promotes death of human cytomegalovirus-infected peripheral blood monocytes via apoptosis and necroptosis.
Cheung J, Remiszewski S, Chiang LW, Ahmad E, Pal M, Rahman SA, Nikolovska-Coleska Z, Chan GC. | 08/31/2023 |
| DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining. | DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.
Head PE, Kapoor-Vazirani P, Nagaraju GP, Zhang H, Rath SK, Luong NC, Haji-Seyed-Javadi R, Sesay F, Wang SY, Duong DM, Daddacha W, Minten EV, Song B, Danelia D, Liu X, Li S, Ortlund EA, Seyfried NT, Smalley DM, Wang Y, Deng X, Dynan WS, El-Rayes B, Davis AJ, Yu DS., Free PMC Article | 08/30/2023 |
| SIRT2 regulates extracellular vesicle-mediated liver-bone communication. | SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
Lin L, Guo Z, He E, Long X, Wang D, Zhang Y, Guo W, Wei Q, He W, Wu W, Li J, Wo L, Hong D, Zheng J, He M, Zhao Q., Free PMC Article | 06/3/2023 |
| SIRT2 plays complex roles in neuroinflammation neuroimmunology-associated disorders. | SIRT2 plays complex roles in neuroinflammation neuroimmunology-associated disorders.
Lu W, Ji H, Wu D., Free PMC Article | 05/30/2023 |
| Frequency of the rs2015 (T>G) and rs2241703 (G>A) polymorphisms in the miRNA-SIRT2 gene in type 2 diabetes mellitus in Saudi Arabia. | Frequency of the rs2015 (T>G) and rs2241703 (G>A) polymorphisms in the miRNA-SIRT2 gene in type 2 diabetes mellitus in Saudi Arabia.
Alshaikh NA, Abdelwahab SI, Habibullah MM, Jerah AA, Bakri MA, Kaabi YA., Free PMC Article | 04/19/2023 |
| A novel circ_0018553 protects against angiotensin-induced cardiac hypertrophy in cardiomyocytes by modulating the miR-4731/SIRT2 signaling pathway. | A novel circ_0018553 protects against angiotensin-induced cardiac hypertrophy in cardiomyocytes by modulating the miR-4731/SIRT2 signaling pathway.
Zuo H, Li L, Wang X, Chen S, Liao Z, Wei S, Ruan H, Li T, Chen J. | 02/14/2023 |
| Promotion of Lung Cancer Metastasis by SIRT2-Mediated Extracellular Protein Deacetylation. | Promotion of Lung Cancer Metastasis by SIRT2-Mediated Extracellular Protein Deacetylation.
Wu M, Zhang JB, Xiong YW, Zhao YX, Zheng MG, Huang XL, Huang F, Wu XX, Li X, Fan WJ, Hu L, Zeng YY, Cheng XJ, Yue JC, Du JJ, Chen NN, Wei WX, Yao QH, Lu XM, Huang C, Deng J, Chang ZJ, Liu HB, Zhao TC, Chinn YE., Free PMC Article | 02/4/2023 |
| SIRT2 promotes cell proliferation and migration through mediating ERK1/2 activation and lactosylceramide accumulation in prostate cancer. | SIRT2 promotes cell proliferation and migration through mediating ERK1/2 activation and lactosylceramide accumulation in prostate cancer.
Lin R, Yang Y, Wu E, Zhou M, Wang S, Zhang Q. | 12/24/2022 |
| SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail. | SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.
Tian Y, Liu R, Hou X, Gao Z, Liu X, Zhang W., Free PMC Article | 11/19/2022 |
| Small Changes Make the Difference for SIRT2: Two Different Binding Modes for 3-Arylmercapto-Acylated Lysine Derivatives. | Small Changes Make the Difference for SIRT2: Two Different Binding Modes for 3-Arylmercapto-Acylated Lysine Derivatives.
Kalbas D, Meleshin M, Liebscher S, Zessin M, Melesina J, Schiene-Fischer C, Bülbül EF, Bordusa F, Sippl W, Schutkowski M. | 09/24/2022 |
| Sirt2 promotes white matter oligodendrogenesis during development and in models of neonatal hypoxia. | Sirt2 promotes white matter oligodendrogenesis during development and in models of neonatal hypoxia.
Jablonska B, Adams KL, Kratimenos P, Li Z, Strickland E, Haydar TF, Kusch K, Nave KA, Gallo V., Free PMC Article | 08/20/2022 |
| The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription. | The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription.
Hisada R, Yoshida N, Umeda M, Burbano C, Bhargava R, Scherlinger M, Kono M, Kyttaris VC, Krishfield S, Tsokos GC., Free PMC Article | 06/11/2022 |