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    FKBP5 FKBP prolyl isomerase 5 [ Homo sapiens (human) ]

    Gene ID: 2289, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients.

    KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients.
    Terrelonge M, LaHue SC, Tang C, Movsesyan I, Pullinger CR, Dubal DB, Leung J, Douglas VC., Free PMC Article

    07/26/2024
    The association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment- a systematic review.

    The association of FKBP5 gene polymorphism with genetic susceptibility to depression and response to antidepressant treatment- a systematic review.
    Zhang Y, Yue W, Li J., Free PMC Article

    06/18/2024
    Differential impact of prenatal PTSD symptoms and preconception trauma exposure on placental NR3C1 and FKBP5 methylation.

    Differential impact of prenatal PTSD symptoms and preconception trauma exposure on placental NR3C1 and FKBP5 methylation.
    Stroud LR, Jao NC, Ward LG, Lee SY, Marsit CJ., Free PMC Article

    05/16/2024
    Sex-dependent association of DNA methylation of HPA axis-related gene FKBP5 with obsessive-compulsive disorder.

    Sex-dependent association of DNA methylation of HPA axis-related gene FKBP5 with obsessive-compulsive disorder.
    Seo JH, Kim ST, Jeon S, Kang JI, Kim SJ.

    03/20/2024
    HPA flexibility and FKBP5: promising physiological targets for conservation.

    HPA flexibility and FKBP5: promising physiological targets for conservation.
    Zimmer C, Jimeno B, Martin LB.,

    03/6/2024
    Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders.

    Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders.
    Großmann NL, Weihs A, Kühn L, Sauer S, Röh S, Wiechmann T, Rex-Haffner M, Völzke H, Völker U, Binder EB, Teumer A, Homuth G, Klinger-König J, Grabe HJ., Free PMC Article

    02/28/2024
    Blood mRNA expression levels of glucocorticoid receptors and FKBP5 are associated with depressive disorder and altered HPA axis.

    Blood mRNA expression levels of glucocorticoid receptors and FKBP5 are associated with depressive disorder and altered HPA axis.
    Hori H, Yoshida F, Ishida I, Matsuo J, Ogawa S, Hattori K, Kim Y, Kunugi H.

    02/14/2024
    Decreased mononuclear cell NR3C1 SKA2 and FKPB5 expression levels among adult survivors of suicide bombing terror attacks in childhood are associated with the development of PTSD.

    Decreased mononuclear cell NR3C1 SKA2 and FKPB5 expression levels among adult survivors of suicide bombing terror attacks in childhood are associated with the development of PTSD.
    Goltser-Dubner T, Shalev A, Benarroch F, Canetti L, Yogev M, Kalla C, Masarwa R, Martin J, Pevzner D, Oz O, Saloner C, Amer R, Lavon M, Lotan A, Galili-Weisstub E, Segman R.

    12/23/2023
    FKBP5 associated CD8 T cell infiltration is a novel prognostic biomarker in luminal B breast cancer.

    FKBP5 associated CD8 T cell infiltration is a novel prognostic biomarker in luminal B breast cancer.
    Tong F, Lu G, Zang J, Hao D, Xu W, Chen J, Ding Q, Xiong H., Free PMC Article

    11/27/2023
    Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis.

    Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis.
    Wang X, Song J, Yuan Y, Li L, Abu-Taha I, Heijman J, Sun L, Dobrev S, Kamler M, Xie L, Wehrens XHT, Horrigan FT, Dobrev D, Li N., Free PMC Article

    10/30/2023
    A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain.

    A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain.
    Maiarù M, Acton RJ, Woźniak EL, Mein CA, Bell CG, Géranton SM., Free PMC Article

    10/5/2023
    MicroRNA hsa-miR-320a-3p and Its Targeted mRNA FKBP5 Were Differentially Expressed in Patients with HIV/TB Co-Infection.

    MicroRNA hsa-miR-320a-3p and Its Targeted mRNA FKBP5 Were Differentially Expressed in Patients with HIV/TB Co-Infection.
    Li A, Bao J, Gao S, He Y, Nie X, Hosyanto FF, He X, Li T, Xu L.

    09/13/2023
    Epigenetic differences in stress response gene FKBP5 among children with abusive vs accidental injuries.

    Epigenetic differences in stress response gene FKBP5 among children with abusive vs accidental injuries.
    Everson TM, Kaczor K, Makoroff K, Meyers G, Rosado N, Charleston E, Bertocci G, Young A, Flores J, Lehnig K, Pierce MC.

    07/21/2023
    FKBP5, a Modulator of Stress Responses Involved in Malignant Mesothelioma: The Link between Stress and Cancer.

    FKBP5, a Modulator of Stress Responses Involved in Malignant Mesothelioma: The Link between Stress and Cancer.
    Cugliari G., Free PMC Article

    06/7/2023
    Potential role of FKBP5 single-nucleotide polymorphisms in functional seizures.

    Potential role of FKBP5 single-nucleotide polymorphisms in functional seizures.
    Asadi-Pooya AA, Simani L, Asadollahi M, Rashidi FS, Ahmadipour E, Alavi A, Roozbeh M, Akbari N, Firouzabadi N., Free PMC Article

    06/5/2023
    Sequencing of 19,219 exomes identifies a low-frequency variant in FKBP5 promoter predisposing to high myopia in a Han Chinese population.

    Sequencing of 19,219 exomes identifies a low-frequency variant in FKBP5 promoter predisposing to high myopia in a Han Chinese population.
    Su J, Yuan J, Xu L, Xing S, Sun M, Yao Y, Ma Y, Chen F, Jiang L, Li K, Yu X, Xue Z, Zhang Y, Fan D, Zhang J, Liu H, Liu X, Zhang G, Wang H, Zhou M, Lyu F, An G, Yu X, Myopia Associated Genetics and Intervention Consortium, Xue Y, Yang J, Qu J.

    06/5/2023
    DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression.

    DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression.
    Mendonça MS, Mangiavacchi PM, Mendes AV, Loureiro SR, Martín-Santos R, Glória LS, Marques W, De Marco SPG, Kanashiro MM, Hallak JEC, Crippa JAS, Rios ÁFL.

    04/19/2023
    Longitudinal relation between maladaptive parenting and nonsuicidal self-injury among Chinese early adolescents: The roles of internalizing symptoms and FKBP5 gene variation.

    Longitudinal relation between maladaptive parenting and nonsuicidal self-injury among Chinese early adolescents: The roles of internalizing symptoms and FKBP5 gene variation.
    Zhou J, Gong X.

    04/14/2023
    Circ_0000479 promotes proliferation, invasion, migration and inflammation and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes via miR-766/FKBP5 axis.

    Circ_0000479 promotes proliferation, invasion, migration and inflammation and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes via miR-766/FKBP5 axis.
    Zhao P, Ma G, Ma L., Free PMC Article

    03/29/2023
    LncRNA CASC19 Enhances the Radioresistance of Nasopharyngeal Carcinoma by Regulating the miR-340-3p/FKBP5 Axis.

    LncRNA CASC19 Enhances the Radioresistance of Nasopharyngeal Carcinoma by Regulating the miR-340-3p/FKBP5 Axis.
    Liu H, Chen Q, Zheng W, Zhou Y, Bai Y, Pan Y, Zhang J, Shao C., Free PMC Article

    02/22/2023
    Methylation and expression of glucocorticoid receptor exon-1 variants and FKBP5 in teenage suicide-completers.

    Methylation and expression of glucocorticoid receptor exon-1 variants and FKBP5 in teenage suicide-completers.
    Rizavi HS, Khan OS, Zhang H, Bhaumik R, Grayson DR, Pandey GN., Free PMC Article

    02/16/2023
    Association of job stress, FK506 binding protein 51 (FKBP5) gene polymorphisms and their interaction with sleep disturbance.

    Association of job stress, FK506 binding protein 51 (FKBP5) gene polymorphisms and their interaction with sleep disturbance.
    Li P, Wang Y, Liu B, Wu C, He C, Lv X, Jiang Y., Free PMC Article

    02/9/2023
    FKBP5 intron 7 methylation is associated with higher anxiety proneness and smaller right thalamus volume in adolescents.

    FKBP5 intron 7 methylation is associated with higher anxiety proneness and smaller right thalamus volume in adolescents.
    Womersley JS, Roeh S, Martin L, Ahmed-Leitao F, Sauer S, Rex-Haffner M, Hemmings SMJ, Binder EB, Seedat S.

    11/5/2022
    Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans.

    Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans.
    Beach SRH, Ong ML, Lei MK, Carter SE, Simons RL, Gibbons FX, Philibert RA., Free PMC Article

    09/24/2022
    The GR-FKBP51 interaction modulates fear memory but not spatial or recognition memory.

    The GR-FKBP51 interaction modulates fear memory but not spatial or recognition memory.
    Jiang A, Zhou C, Samsom J, Yan S, Yu DZ, Jia ZP, Wong AHC, Liu F.

    09/17/2022
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