| FKBP4 promotes glycolysis and hepatocellular carcinoma progression via p53/HK2 axis. | FKBP4 promotes glycolysis and hepatocellular carcinoma progression via p53/HK2 axis.
Zeng Z, Xu S, Wang R, Han X., Free PMC Article | 11/8/2024 |
| FKBP4 correlates with CD8[+] T cells and lymphatic metastases in oral squamous cell carcinoma. | FKBP4 correlates with CD8(+) T cells and lymphatic metastases in oral squamous cell carcinoma.
Zhang Y, Wang J, Yu J, Zhu H. | 03/1/2024 |
| Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations. | Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations.
Kojima R, Paslawski W, Lyu G, Arenas E, Zhang X, Svenningsson P., Free PMC Article | 02/6/2024 |
| Impact of FKBP52 on cell proliferation and hormone-dependent cancers. | Impact of FKBP52 on cell proliferation and hormone-dependent cancers.
Hanaki S, Shimada M., Free PMC Article | 07/17/2023 |
| Concomitant Neuronal Tau Deposition and FKBP52 Decrease Is an Early Feature of Different Human and Experimental Tauopathies. | Concomitant Neuronal Tau Deposition and FKBP52 Decrease Is an Early Feature of Different Human and Experimental Tauopathies.
Meduri G, Guillemeau K, Daguinot C, Dounane O, Genet M, Ferrara L, Chambraud B, Baulieu EE, Giustiniani J., Free PMC Article | 07/7/2023 |
| E2F Transcription Factor 1 Activates FKBP Prolyl Isomerase 4 to Promote Angiogenesis in Cervical Squamous Cell Carcinoma Via the PI3K/AKT Signaling Pathway. | E2F Transcription Factor 1 Activates FKBP Prolyl Isomerase 4 to Promote Angiogenesis in Cervical Squamous Cell Carcinoma Via the PI3K/AKT Signaling Pathway.
Huang J, Zhao Y. | 05/10/2023 |
| Functions of the Hsp90-Binding FKBP Immunophilins. | Functions of the Hsp90-Binding FKBP Immunophilins.
Ortiz NR, Guy N, Garcia YA, Sivils JC, Galigniana MD, Cox MB. | 12/31/2022 |
| LncRNA MAFG-AS1 deregulated in breast cancer affects autophagy and progression of breast cancer by interacting with miR-3612 and FKBP4 invitro. | LncRNA MAFG-AS1 deregulated in breast cancer affects autophagy and progression of breast cancer by interacting with miR-3612 and FKBP4 invitro.
Gao Z, Zheng G, Gong X, Hu H, Shao L, Pang Y, Wang Y, Qi A. | 07/2/2022 |
| FKBP52 and FKBP51 differentially regulate the stability of estrogen receptor in breast cancer. | FKBP52 and FKBP51 differentially regulate the stability of estrogen receptor in breast cancer.
Habara M, Sato Y, Goshima T, Sakurai M, Imai H, Shimizu H, Katayama Y, Hanaki S, Masaki T, Morimoto M, Nishikawa S, Toyama T, Shimada M., Free PMC Article | 05/14/2022 |
| FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells. | FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells.
Maeda K, Habara M, Kawaguchi M, Matsumoto H, Hanaki S, Masaki T, Sato Y, Matsuyama H, Kunieda K, Nakagawa H, Shimada M., Free PMC Article | 04/16/2022 |
| Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress. | Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
Chambraud B, Daguinot C, Guillemeau K, Genet M, Dounane O, Meduri G, Poüs C, Baulieu EE, Giustiniani J., Free PMC Article | 03/26/2022 |
| KDM5D inhibits the transcriptional activation of FKBP4 by suppressing the expression of E2F1 in colorectal cancer in males. | KDM5D inhibits the transcriptional activation of FKBP4 by suppressing the expression of E2F1 in colorectal cancer in males.
Liu M, Gao N. | 01/8/2022 |
| FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-kappaB signaling. | FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-κB signaling.
Zong S, Jiao Y, Liu X, Mu W, Yuan X, Qu Y, Xia Y, Liu S, Sun H, Wang L, Cui B, Liu X, Li P, Zhao Y., Free PMC Article | 11/6/2021 |
| The Influence Mechanism of Abnormal Immunophilin FKBP52 on the Expression Levels of PR-A and PR-B in Endometriosis Based on Endometrial Stromal Cell Model in Vitro. | The Influence Mechanism of Abnormal Immunophilin FKBP52 on the Expression Levels of PR-A and PR-B in Endometriosis Based on Endometrial Stromal Cell Model in Vitro.
Liu L, Cheng J, Wei F, Pang L, Zhi Z, Yang W, Tan W., Free PMC Article | 10/30/2021 |
| FKBP4 Accelerates Malignant Progression of Non-Small-Cell Lung Cancer by Activating the Akt/mTOR Signaling Pathway. | FKBP4 Accelerates Malignant Progression of Non-Small-Cell Lung Cancer by Activating the Akt/mTOR Signaling Pathway.
Meng W, Meng J, Jiang H, Feng X, Wei D, Ding Q., Free PMC Article | 08/28/2021 |
| Genes involved in glucocorticoid receptor signalling affect susceptibility to mood disorders. | Genes involved in glucocorticoid receptor signalling affect susceptibility to mood disorders.
Szczepankiewicz D, Narożna B, Celichowski P, Sakrajda K, Kołodziejski P, Banach E, Zakowicz P, Pruszyńska-Oszmałek E, Pawlak J, Wiłkość M, Dmitrzak-Węglarz M, Skibińska M, Bejger A, Twarowska-Hauser J, Rybakowski JK, Nogowski L, Szczepankiewicz A. | 08/21/2021 |
| Associations of FKBP4 and FKBP5 gene polymorphisms with disease susceptibility, glucocorticoid efficacy, anxiety, depression, and health-related quality of life in systemic lupus erythematosus patients. | Associations of FKBP4 and FKBP5 gene polymorphisms with disease susceptibility, glucocorticoid efficacy, anxiety, depression, and health-related quality of life in systemic lupus erythematosus patients.
Lou QY, Li Z, Teng Y, Xie QM, Zhang M, Huang SW, Li WF, Chen YF, Pan FM, Xu SQ, Cai J, Liu S, Tao JH, Liu SX, Huang HL, Wang F, Pan HF, Su H, Xu ZW, Hu WB, Zou YF. | 06/26/2021 |
| The FKBP4 Gene, Encoding a Regulator of the Androgen Receptor Signaling Pathway, Is a Novel Candidate Gene for Androgen Insensitivity Syndrome. | The FKBP4 Gene, Encoding a Regulator of the Androgen Receptor Signaling Pathway, Is a Novel Candidate Gene for Androgen Insensitivity Syndrome.
Ilaslan E, Markosyan R, Sproll P, Stevenson BJ, Sajek M, Sajek MP, Hayrapetyan H, Sarkisian T, Livshits L, Nef S, Jaruzelska J, Kusz-Zamelczyk K., Free PMC Article | 05/22/2021 |
| FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer. | FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer.
Mangé A, Coyaud E, Desmetz C, Laurent E, Béganton B, Coopman P, Raught B, Solassol J., Free PMC Article | 10/24/2020 |
| The study therefore strongly implicates FKBP4 as associated with fetal losses in humans, particularly in the Asian population. | Exome sequencing identifies variants in FKBP4 that are associated with recurrent fetal loss in humans.
Demetriou C, Chanudet E, GOSgene, Joseph A, Topf M, Thomas AC, Bitner-Glindzicz M, Regan L, Stanier P, Moore GE. | 05/23/2020 |
| elevated FKBP4 expression was associated with poor survival of patients with hormone-naive prostate cancer | Delineation of human prostate cancer evolution identifies chromothripsis as a polyclonal event and FKBP4 as a potential driver of castration resistance.
Federer-Gsponer JR, Quintavalle C, Müller DC, Dietsche T, Perrina V, Lorber T, Juskevicius D, Lenkiewicz E, Zellweger T, Gasser T, Barrett MT, Rentsch CA, Bubendorf L, Ruiz C. | 10/19/2019 |
| ID4 selectively regulates AR activity through direct interaction with FKBP52. | Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52.
Joshi JB, Patel D, Morton DJ, Sharma P, Zou J, Hewa Bostanthirige D, Gorantla Y, Nagappan P, Komaragiri SK, Sivils JC, Xie H, Palaniappan R, Wang G, Cox MB, Chaudhary J., Free PMC Article | 11/4/2017 |
| FKBP52 could be abnormally released from NFTs negative neurons in AD brains in correlation with the early pathologic Tau-D(421) neuronal accumulation. | Caspase-cleaved Tau-D(421) is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons.
Meduri G, Guillemeau K, Dounane O, Sazdovitch V, Duyckaerts C, Chambraud B, Baulieu EE, Giustiniani J. | 09/30/2017 |
| Mechanistically, USP49 deubiquitinates and stabilizes FKBP51, which in turn enhances PHLPP's capability to dephosphorylate AKT. | USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.
Luo K, Li Y, Yin Y, Li L, Wu C, Chen Y, Nowsheen S, Hu Q, Zhang L, Lou Z, Yuan J., Free PMC Article | 07/15/2017 |
| Low expression of FKBP4 is associated with Progesterone Resistance in Endometriosis. | Progesterone Resistance in Endometriosis Is Modulated by the Altered Expression of MicroRNA-29c and FKBP4.
Joshi NR, Miyadahira EH, Afshar Y, Jeong JW, Young SL, Lessey BA, Serafini PC, Fazleabas AT., Free PMC Article | 06/24/2017 |