| MAVS signaling shapes microglia responses to neurotropic virus infection. | MAVS signaling shapes microglia responses to neurotropic virus infection.
Gern OL, Pavlou A, Mulenge F, Busker LM, Ghita L, Aringo A, Costa B, Spanier J, Waltl I, Stangel M, Kalinke U., Free PMC Article | 10/28/2024 |
| Fetal MAVS and type I IFN signaling pathways control ZIKV infection in the placenta and maternal decidua. | Fetal MAVS and type I IFN signaling pathways control ZIKV infection in the placenta and maternal decidua.
Alippe Y, Wang L, Coskun R, Muraro SP, Zhao FR, Elam-Noll M, White JM, Vota DM, Hauk VC, Gordon JI, Handley SA, Diamond MS., | 08/23/2024 |
| Dual modifying of MAVS at lysine 7 by SIRT3-catalyzed deacetylation and SIRT5-catalyzed desuccinylation orchestrates antiviral innate immunity. | Dual modifying of MAVS at lysine 7 by SIRT3-catalyzed deacetylation and SIRT5-catalyzed desuccinylation orchestrates antiviral innate immunity.
Liu X, Zhu C, Jia S, Deng H, Tang J, Sun X, Zeng X, Chen X, Wang Z, Liu W, Liao Q, Zha H, Cai X, Xiao W., Free PMC Article | 04/26/2024 |
| MAVS promotes interferon signaling in RNA virus infection by ZUFSP-mediated chromatin regulation. | MAVS promotes interferon signaling in RNA virus infection by ZUFSP-mediated chromatin regulation.
Li T, Li S. | 04/12/2024 |
| The aldehyde dehydrogenase ALDH1B1 exerts antiviral effects through the aggregation of the adaptor MAVS. | The aldehyde dehydrogenase ALDH1B1 exerts antiviral effects through the aggregation of the adaptor MAVS.
Sun N, Cai Q, Zhang Y, Zhang RR, Jiang J, Yang H, Qin CF, Cheng G. | 01/12/2024 |
| 3beta-hydroxysteroid-Delta24 reductase dampens anti-viral innate immune responses by targeting K27 ubiquitination of MAVS and STING. | 3β-hydroxysteroid-Δ24 reductase dampens anti-viral innate immune responses by targeting K27 ubiquitination of MAVS and STING.
Liu Q, Chen S, Tian R, Xue B, Li H, Guo M, Liu S, Yan M, You R, Wang L, Yang D, Wan M, Zhu H., Free PMC Article | 01/4/2024 |
| MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade. | MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade.
Liu F, Zhuang W, Song B, Yang Y, Liu J, Zheng Y, Liu B, Zheng J, Zhao W, Gao C., Free PMC Article | 10/5/2023 |
| MAVS integrates glucose metabolism and RIG-I-like receptor signaling. | MAVS integrates glucose metabolism and RIG-I-like receptor signaling.
He QQ, Huang Y, Nie L, Ren S, Xu G, Deng F, Cheng Z, Zuo Q, Zhang L, Cai H, Wang Q, Wang F, Ren H, Yan H, Xu K, Zhou L, Lu M, Lu Z, Zhu Y, Liu S., Free PMC Article | 09/8/2023 |
| MAVS Positively Regulates Mitochondrial Integrity and Metabolic Fitness in B Cells. | MAVS Positively Regulates Mitochondrial Integrity and Metabolic Fitness in B Cells.
Wang H, Sun W, Traba J, Wu J, Qi CF, Amo L, Kole HK, Scott B, Singh K, Sack MN, Bolland S., Free PMC Article | 08/30/2023 |
| WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response. | WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response.
Li J, Zhang R, Wang C, Zhu J, Ren M, Jiang Y, Hou X, Du Y, Wu Q, Qi S, Li L, Chen S, Yang H, Hou F., Free PMC Article | 08/16/2023 |
| MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation. | MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation.
Noval MG, Spector SN, Bartnicki E, Izzo F, Narula N, Yeung ST, Damani-Yokota P, Dewan MZ, Mezzano V, Rodriguez-Rodriguez BA, Loomis C, Khanna KM, Stapleford KA., Free PMC Article | 08/7/2023 |
| Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling. | Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.
Rupani DN, Thege FI, Chandra V, Rajaei H, Cowan RW, Wörmann SM, Le Roux O, Malaney P, Manning SL, Hashem J, Bailey-Lundberg J, Rhim AD, McAllister F., Free PMC Article | 01/21/2023 |
| BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS. | BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS.
Huang JP, Li J, Xiao YP, Xu LG., Free PMC Article | 09/17/2022 |
| A conventional immune regulator mitochondrial antiviral signaling protein blocks hepatic steatosis by maintaining mitochondrial homeostasis. | A conventional immune regulator mitochondrial antiviral signaling protein blocks hepatic steatosis by maintaining mitochondrial homeostasis.
Fu J, Hu F, Ma T, Zhao WJ, Tian H, Zhang Y, Hu M, Zhou J, Zhang Y, Jian C, Ji YX, Zhang XJ, Jiang J, She ZG, Cheng X, Zhang P, Bai L, Yang J, Li H. | 03/5/2022 |
| Methyltransferase-Like Protein 14 Attenuates Mitochondrial Antiviral Signaling Protein Expression to Negatively Regulate Antiviral Immunity via N(6) -methyladenosine Modification. | Methyltransferase-Like Protein 14 Attenuates Mitochondrial Antiviral Signaling Protein Expression to Negatively Regulate Antiviral Immunity via N(6) -methyladenosine Modification.
Qin F, Cai B, Zhao J, Zhang L, Zheng Y, Liu B, Gao C., Free PMC Article | 01/22/2022 |
| Innate Immune Nod1/RIP2 Signaling Is Essential for Cardiac Hypertrophy but Requires Mitochondrial Antiviral Signaling Protein for Signal Transductions and Energy Balance. | Innate Immune Nod1/RIP2 Signaling Is Essential for Cardiac Hypertrophy but Requires Mitochondrial Antiviral Signaling Protein for Signal Transductions and Energy Balance.
Lin HB, Naito K, Oh Y, Farber G, Kanaan G, Valaperti A, Dawood F, Zhang L, Li GH, Smyth D, Moon M, Liu Y, Liang W, Rotstein B, Philpott DJ, Kim KH, Harper ME, Liu PP. | 10/16/2021 |
| Novel insights into stress-induced susceptibility to influenza: corticosterone impacts interferon-beta responses by Mfn2-mediated ubiquitin degradation of MAVS. | Novel insights into stress-induced susceptibility to influenza: corticosterone impacts interferon-β responses by Mfn2-mediated ubiquitin degradation of MAVS.
Luo Z, Liu LF, Jiang YN, Tang LP, Li W, Ouyang SH, Tu LF, Wu YP, Gong HB, Yan CY, Jiang S, Lu YH, Liu T, Jiang Z, Kurihara H, Yu Y, Yao XS, Li YF, He RR., Free PMC Article | 10/16/2021 |
| SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA. | SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA.
Guo W, Wei J, Zhong X, Zang R, Lian H, Hu MM, Li S, Shu HB, Yang Q., Free PMC Article | 10/2/2021 |
| PINK1 Inhibits Multimeric Aggregation and Signaling of MAVS and MAVS-Dependent Lung Pathology. | PINK1 Inhibits Multimeric Aggregation and Signaling of MAVS and MAVS-Dependent Lung Pathology.
Kim SH, Shin HJ, Yoon CM, Lee SW, Sharma L, Dela Cruz CS, Kang MJ., Free PMC Article | 07/31/2021 |
| MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice. | MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice.
Paulsen M, Varese A, Pinpathomrat N, Kirsebom FCM, Paulsen M, Johansson C., Free PMC Article | 06/19/2021 |
| USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS. | USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
Hou J, Han L, Zhao Z, Liu H, Zhang L, Ma C, Yi F, Liu B, Zheng Y, Gao C., Free PMC Article | 06/5/2021 |
| SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation. | SIRT5 impairs aggregation and activation of the signaling adaptor MAVS through catalyzing lysine desuccinylation.
Liu X, Zhu C, Zha H, Tang J, Rong F, Chen X, Fan S, Xu C, Du J, Zhu J, Wang J, Ouyang G, Yu G, Cai X, Chen Z, Xiao W., Free PMC Article | 04/13/2021 |
| The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis. | The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis.
Zhang W, Gong J, Yang H, Wan L, Peng Y, Wang X, Sun J, Li F, Geng Y, Li D, Liu N, Mei G, Cao Y, Yan Q, Li H, Zhang Y, He X, Zhang Q, Zhang R, Wu F, Zhong H, Wei C. | 03/20/2021 |
| RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA. | RNF115 plays dual roles in innate antiviral responses by catalyzing distinct ubiquitination of MAVS and MITA.
Zhang ZD, Xiong TC, Yao SQ, Wei MC, Chen M, Lin D, Zhong B., Free PMC Article | 11/21/2020 |
| The Japanese Encephalitis Virus NS1' Protein Inhibits Type I IFN Production by Targeting MAVS. | The Japanese Encephalitis Virus NS1' Protein Inhibits Type I IFN Production by Targeting MAVS.
Zhou D, Li Q, Jia F, Zhang L, Wan S, Li Y, Song Y, Chen H, Cao S, Ye J. | 09/12/2020 |