| Zfp281 and Zfp148 control CD4[+] T cell thymic development and TH2 functions. | Zfp281 and Zfp148 control CD4(+) T cell thymic development and T(H)2 functions.
Chopp LB, Zhu X, Gao Y, Nie J, Singh J, Kumar P, Young KZ, Patel S, Li C, Balmaceno-Criss M, Vacchio MS, Wang MM, Livak F, Merchant JL, Wang L, Kelly MC, Zhu J, Bosselut R. | 11/14/2023 |
| Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis. | Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis.
Kuang LW, Zhang CC, Li BH, Liu HZ, Wang H, Li GC. | 03/4/2023 |
| beta Cell-specific deletion of Zfp148 improves nutrient-stimulated beta cell Ca2+ responses. | β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses.
Emfinger CH, de Klerk E, Schueler KL, Rabaglia ME, Stapleton DS, Simonett SP, Mitok KA, Wang Z, Liu X, Paulo JA, Yu Q, Cardone RL, Foster HR, Lewandowski SL, Perales JC, Kendziorski CM, Gygi SP, Kibbey RG, Keller MP, Hebrok M, Merrins MJ, Attie AD., Free PMC Article | 05/28/2022 |
| Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway. | Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway.
Zou ZV, Gul N, Lindberg M, Bokhari AA, Eklund EM, Garellick V, Patel AAH, Dzanan JJ, Titmuss BO, Le Gal K, Johansson I, Tivesten Å, Forssell-Aronsson E, Bergö MO, Staffas A, Larsson E, Sayin VI, Lindahl P., Free PMC Article | 01/9/2021 |
| ZFP148 is important in the regulation of proliferation, smooth muscle gene downregulation, and apoptosis in aneurysm development. | ZFP148 (Zinc-Finger Protein 148) Binds Cooperatively With NF-1 (Neurofibromin 1) to Inhibit Smooth Muscle Marker Gene Expression During Abdominal Aortic Aneurysm Formation.
Salmon M, Schaheen B, Spinosa M, Montgomery W, Pope NH, Davis JP, Johnston WF, Sharma AK, Owens GK, Merchant JL, Zehner ZE, Upchurch GR Jr, Ailawadi G., Free PMC Article | 12/7/2019 |
| Data indicate zinc finger protein 148 (ZFP148) as a transcription factor that differentially binds to the zinc finger protein 30 protein (Zfp30) promoter region harboring rs51434084. | Differential Regulation of Zfp30 Expression in Murine Airway Epithelia Through Altered Binding of ZFP148 to rs51434084.
Laudermilk LT, Thomas JM, Kelada SN., Free PMC Article | 10/13/2018 |
| The results suggest that Zfp148 controls the fate of newly transformed intestinal tumor cells by repressing p53 and that targeting Zfp148 might be useful in the treatment of colorectal cancer. | Targeting Zfp148 activates p53 and reduces tumor initiation in the gut.
Nilton A, Sayin VI, Zou ZV, Sayin SI, Bondjers C, Gul N, Agren P, Fogelstrand P, Nilsson O, Bergo MO, Lindahl P., Free PMC Article | 01/20/2018 |
| Zfp148 deficiency increases p53 activity and protects against atherosclerosis by causing proliferation arrest of lesional macrophages. | Loss of one copy of Zfp148 reduces lesional macrophage proliferation and atherosclerosis in mice by activating p53.
Sayin VI, Khan OM, Pehlivanoglu LE, Staffas A, Ibrahim MX, Asplund A, Agren P, Nilton A, Bergström G, Bergo MO, Borén J, Lindahl P. | 12/20/2014 |
| These data identify an important role for ZBP-89 in regulating stress hematopoiesis in adult mouse bone marrow. | Stress hematopoiesis is regulated by the Krüppel-like transcription factor ZBP-89.
Li X, Romain RD, Park D, Scadden DT, Merchant JL, Arnaout MA., Free PMC Article | 10/11/2014 |
| Results indicate that Zfp148-deficient mice generate normal mature hematopoietic populations. | Zinc finger protein 148 is dispensable for primitive and definitive hematopoiesis in mice.
Nilton A, Sayin VI, Staffas A, Larsson E, Rolf J, Petit MM, Palmqvist L, Swolin B, Cardell S, Lindahl P., Free PMC Article | 04/26/2014 |
| Zfp148 deficiency causes lung maturation defects and lethality. | Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment.
Sayin VI, Nilton A, Ibrahim MX, Ågren P, Larsson E, Petit MM, Hultén LM, Ståhlman M, Johansson BR, Bergo MO, Lindahl P., Free PMC Article | 08/31/2013 |
| ZBP-89 is required for expression of the Tph1 gene and subsequent production of 5HT in response to bacterial infection in mice. Reductions in epithelial ZBP-89 increase susceptibility to colitis and sepsis after infection with S. typhimurium. | ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice.
Essien BE, Grasberger H, Romain RD, Law DJ, Veniaminova NA, Saqui-Salces M, El-Zaatari M, Tessier A, Hayes MM, Yang AC, Merchant JL., Free PMC Article | 08/3/2013 |
| MiR-203 expression downregulated ZFP-148 mRNA translation by specifically targeting its 3' UTR, which resulted in differential expression of its downstream target genes, which in turn promote cell survival to foster Coxsackievirus B3 replication | MicroRNA-203 enhances coxsackievirus B3 replication through targeting zinc finger protein-148.
Hemida MG, Ye X, Zhang HM, Hanson PJ, Liu Z, McManus BM, Yang D., Free PMC Article | 03/2/2013 |
| the G(5) string is necessary for Gata1 gene expression in vivo and ZBP-89 is the functional trans-acting factor for this cis-acting region. | Characterization of a functional ZBP-89 binding site that mediates Gata1 gene expression during hematopoietic development.
Ohneda K, Ohmori S, Ishijima Y, Nakano M, Yamamoto M., Free PMC Article | 01/21/2010 |
| The transcriptional repressor ZBP-89 and the lack of Sp1/Sp3, c-jun and Stat3 are important for the down-regulation of the vimentin gene during C2C12 myogenesis. | The transcriptional repressor ZBP-89 and the lack of Sp1/Sp3, c-Jun and Stat3 are important for the down-regulation of the vimentin gene during C2C12 myogenesis.
Salmon M, Zehner ZE., Free PMC Article | 01/21/2010 |
| identify ZBP-89 as being a novel transcription factor involved in erythroid and megakaryocytic development and suggest that it serves a cooperative function with GATA-1 and/or FOG-1 in a developmental stage-specific manner | Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development.
Woo AJ, Moran TB, Schindler YL, Choe SK, Langer NB, Sullivan MR, Fujiwara Y, Paw BH, Cantor AB., Free PMC Article | 01/21/2010 |
| ataxia telangiectasia mutated protein phosphorylation of ZBP-89 contributes to Histone deacetylase inhibitors induction of p21(waf1) gene expression | ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate.
Bai L, Merchant JL., Free PMC Article | 01/21/2010 |