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    FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens (human) ]

    Gene ID: 2263, updated on 1-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Expression of fibroblast growth factor receptor 2 (FGFR2) in combined hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma: clinicopathological study.

    Expression of fibroblast growth factor receptor 2 (FGFR2) in combined hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma: clinicopathological study.
    Sasaki M, Sato Y, Nakanuma Y., Free PMC Article

    06/28/2024
    Perinatal imaging findings of a fetus with Pfeiffer syndrome and a heterozygous c.1019A>G, p.Tyr340Cys (Y340C) mutation in FGFR2 presenting a cloverleaf skull, craniosynostosis and short limbs on prenatal ultrasound mimicking thanatophoric dysplasia type II.

    Perinatal imaging findings of a fetus with Pfeiffer syndrome and a heterozygous c.1019A>G, p.Tyr340Cys (Y340C) mutation in FGFR2 presenting a cloverleaf skull, craniosynostosis and short limbs on prenatal ultrasound mimicking thanatophoric dysplasia type II.
    Chen CP, Huang JP, Huang KS, Chen YY, Wu FT, Pan YT, Chiu CL, Wang W.

    05/30/2024
    Elucidating the Role of Wildtype and Variant FGFR2 Structural Dynamics in (Dys)Function and Disorder.

    Elucidating the Role of Wildtype and Variant FGFR2 Structural Dynamics in (Dys)Function and Disorder.
    Lian Y, Bodian D, Shehu A., Free PMC Article

    05/13/2024
    Superficial acral calcified chondroid mesenchymal neoplasm harboring an FN1::FGFR2 fusion and review of the literature.

    Superficial acral calcified chondroid mesenchymal neoplasm harboring an FN1::FGFR2 fusion and review of the literature.
    Machado I, Damaskou V, Ioannidis E, Jour G, Linos K.,

    04/12/2024
    Genetic insights into the 'sandwich fusion' subtype of Klippel-Feil syndrome: novel FGFR2 mutations identified by 21 cases of whole-exome sequencing.

    Genetic insights into the 'sandwich fusion' subtype of Klippel-Feil syndrome: novel FGFR2 mutations identified by 21 cases of whole-exome sequencing.
    Xu N, Hung KL, Gong X, Fan D, Tian Y, Yan M, Wei Y, Wang S., Free PMC Article

    04/5/2024
    Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes.

    Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes.
    Schmidt J, Kaulfuß S, Ott H, Gaubert M, Reintjes N, Bremmer F, Dreha-Kulaczewski S, Stroebel P, Yigit G, Wollnik B., Free PMC Article

    02/23/2024
    Investigating FGFR2 gene as a blood-based epigenetic biomarker in gastric cancer.

    Investigating FGFR2 gene as a blood-based epigenetic biomarker in gastric cancer.
    Aleyasin SA, Moradi A, Abolhasani N, Abdollahi M.

    02/12/2024
    FGFR2 genetic variants in women with breast cancer.

    FGFR2 genetic variants in women with breast cancer.
    Dix-Peek T, Dickens C, Augustine TN, Phakathi BP, Van Den Berg EJ, Joffe M, Ayeni OA, Cubasch H, Nietz S, Mathew CG, Hayat M, Neugut AI, Jacobson JS, Ruff P, Duarte RAB., Free PMC Article

    11/28/2023
    Facial skeleton dysmorphology in syndromic craniosynostosis: differences between FGFR2 and no-FGFR2-related syndromes and relationship with skull base and facial sutural patterns.

    Facial skeleton dysmorphology in syndromic craniosynostosis: differences between FGFR2 and no-FGFR2-related syndromes and relationship with skull base and facial sutural patterns.
    Calandrelli R, Pilato F, Massimi L, D'Apolito G, Colosimo C.

    11/16/2023
    miRNA-381-3p Functions as a Tumor Suppressor to Inhibit Gastric Cancer by Targeting Fibroblast Growth Factor Receptor-2.

    miRNA-381-3p Functions as a Tumor Suppressor to Inhibit Gastric Cancer by Targeting Fibroblast Growth Factor Receptor-2.
    Gao X, Liu H, Wu Q, Wang R, Huang M, Ma Q, Liu Y.

    10/30/2023
    Postzygotic gain-of-function variants in FGFR2 in two patients with hair follicle naevus.

    Postzygotic gain-of-function variants in FGFR2 in two patients with hair follicle naevus.
    Cheng Q, Yang F, Xue R, Wang H, Lin Z.

    10/28/2023
    Functional Distinctions of Endometrial Cancer-Associated Mutations in the Fibroblast Growth Factor Receptor 2 Gene.

    Functional Distinctions of Endometrial Cancer-Associated Mutations in the Fibroblast Growth Factor Receptor 2 Gene.
    Dixit G, Pappas BA, Bhardwaj G, Schanz W, Maretzky T., Free PMC Article

    10/24/2023
    Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion.

    Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion.
    Alshahrany N, Begum A, Siebzehnrubl D, Jimenez-Pascual A, Siebzehnrubl FA., Free PMC Article

    09/1/2023
    Integrating transcriptomics and genomics to identify fibroblast growth factor/receptor candidate genes for non-syndromic orofacial cleft in Chinese.

    Integrating transcriptomics and genomics to identify fibroblast growth factor/receptor candidate genes for non-syndromic orofacial cleft in Chinese.
    Ge B, Lin Y, Shi B, Jia Z.

    07/17/2023
    FGF10/FGFR2 Signaling: Therapeutically Targetable Vulnerability in Ligand-responsive Cholangiocarcinoma Cells.

    FGF10/FGFR2 Signaling: Therapeutically Targetable Vulnerability in Ligand-responsive Cholangiocarcinoma Cells.
    Oeurn K, Jusakul A, Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S., Free PMC Article

    06/30/2023
    FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin beta1 Degradation.

    FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation.
    Mieczkowski K, Popeda M, Lesniak D, Sadej R, Kitowska K., Free PMC Article

    05/19/2023
    FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways.

    FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways.
    Dixit G, Gonzalez-Bosquet J, Skurski J, Devor EJ, Dickerson EB, Nothnick WB, Issuree PD, Leslie KK, Maretzky T., Free PMC Article

    05/15/2023
    FGFR2 modulates the Akt/Nrf2/ARE signaling pathway to improve angiotensin II-induced hypertension-related endothelial dysfunction.

    FGFR2 modulates the Akt/Nrf2/ARE signaling pathway to improve angiotensin II-induced hypertension-related endothelial dysfunction.
    Jiao K, Su P, Li Y.

    05/12/2023
    Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma.

    Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma.
    Goyal L, Meric-Bernstam F, Hollebecque A, Valle JW, Morizane C, Karasic TB, Abrams TA, Furuse J, Kelley RK, Cassier PA, Klümpen HJ, Chang HM, Chen LT, Tabernero J, Oh DY, Mahipal A, Moehler M, Mitchell EP, Komatsu Y, Masuda K, Ahn D, Epstein RS, Halim AB, Fu Y, Salimi T, Wacheck V, He Y, Liu M, Benhadji KA, Bridgewater JA, FOENIX-CCA2 Study Investigators.

    01/28/2023
    Malrotation and Fibroblast Growth Factor Receptor-2-Associated Craniosynostosis: An Underrecognized Association and Management Pathway.

    Malrotation and Fibroblast Growth Factor Receptor-2-Associated Craniosynostosis: An Underrecognized Association and Management Pathway.
    Harwood R, O'Shea K, Hennedige A, Parks C, Turnock C, Wood S.

    01/21/2023
    Aberrations in FGFR1, FGFR2, and RIP5 Expression in Human Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).

    Aberrations in FGFR1, FGFR2, and RIP5 Expression in Human Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).
    Kelam N, Racetin A, Polović M, Benzon B, Ogorevc M, Vukojević K, Glavina Durdov M, Dunatov Huljev A, Kuzmić Prusac I, Čarić D, Raguž F, Kostić S., Free PMC Article

    01/11/2023
    Identification of Diagnostic Variants in FGFR2 and NPR2 Genes in a Chinese Family Affected by Crouzon Syndrome and Acromesomelic Dysplasia, Type Maroteaux.

    Identification of Diagnostic Variants in FGFR2 and NPR2 Genes in a Chinese Family Affected by Crouzon Syndrome and Acromesomelic Dysplasia, Type Maroteaux.
    Zhu J, Meng R, Zhao H, Cai L, Wen X, Zeng W, Luo Y, Qi H.

    11/19/2022
    Impact of FGFR2 gene fusions on survival of patients with intrahepatic cholangiocarcinoma following curative intent resection.

    Impact of FGFR2 gene fusions on survival of patients with intrahepatic cholangiocarcinoma following curative intent resection.
    Buckarma E, De La Cruz G, Truty M, Nagorney D, Cleary S, Kendrick M, Borad M, Graham RP, Gores G, Smoot R.

    10/29/2022
    FGFR2 Mutation p.Cys342Arg Enhances Mitochondrial Metabolism-Mediated Osteogenesis via FGF/FGFR-AMPK-Erk1/2 Axis in Crouzon Syndrome.

    FGFR2 Mutation p.Cys342Arg Enhances Mitochondrial Metabolism-Mediated Osteogenesis via FGF/FGFR-AMPK-Erk1/2 Axis in Crouzon Syndrome.
    Wang Y, Liu Y, Chen H, Liu X, Zhang Y, Wang Y, Gu Y., Free PMC Article

    10/22/2022
    FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.

    FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.
    Moes-Sosnowska J, Skupinska M, Lechowicz U, Szczepulska-Wojcik E, Skronska P, Rozy A, Stepniewska A, Langfort R, Rudzinski P, Orlowski T, Popiel D, Stanczak A, Wieczorek M, Chorostowska-Wynimko J., Free PMC Article

    10/8/2022
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