| Cold-induced Yes-associated-protein expression through miR-429 mediates the browning of white adipose tissue. | Cold-induced Yes-associated-protein expression through miR-429 mediates the browning of white adipose tissue.
Ye C, Duan J, Zhang X, Yao L, Song Y, Wang G, Li Q, Wang B, Ai D, Wang C, Zhu Y. | 01/1/2022 |
| AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis. | AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis.
Francisco J, Zhang Y, Nakada Y, Jeong JI, Huang CY, Ivessa A, Oka S, Babu GJ, Del Re DP., Free PMC Article | 11/13/2021 |
| Differential effects of the Src family tyrosine kinases Yes and Fyn on lipopolysaccharide-induced lung injury in ice. | Differential effects of the Src family tyrosine kinases Yes and Fyn on lipopolysaccharide-induced lung injury in mice.
Trittmann JK, Jin Y, Liu Y, Nelin LD., Free PMC Article | 09/25/2021 |
| Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis. | Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis.
Singh BN, Gong W, Das S, Theisen JWM, Sierra-Pagan JE, Yannopoulos D, Skie E, Shah P, Garry MG, Garry DJ., Free PMC Article | 10/24/2020 |
| MicroRNA-140 attenuates myocardial ischemia-reperfusion injury through suppressing mitochondria-mediated apoptosis by targeting YES1. | MicroRNA-140 attenuates myocardial ischemia-reperfusion injury through suppressing mitochondria-mediated apoptosis by targeting YES1.
Yang S, Li H, Chen L. | 06/20/2020 |
| a novel insight into the molecular mechanisms underlying lung development and contribute to a better understanding of the characteristics of TAZ-transcriptional coactivator with PDZ-binding motif and YAP | Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development.
Isago H, Mitani A, Mikami Y, Horie M, Urushiyama H, Hamamoto R, Terasaki Y, Nagase T. | 05/16/2020 |
| results suggest that Yes-associated protein fine-tunes the expression of genes associated with spermatogonial fate commitment, but that its loss is not sufficient to alter spermatogenesis in vivo | Yes-associated protein expression in germ cells is dispensable for spermatogenesis in mice.
Abou Nader N, Levasseur A, Zhang X, Boerboom D, Nagano MC, Boyer A. | 03/14/2020 |
| Ganglioside GD3 enhances invasiveness of gliomas by forming a complex with PDGFRalpha and Yes Kinase. | Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase.
Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Kotani N, Honke K, Suzumura A, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K., Free PMC Article | 10/3/2015 |
| serum also activates TEAD-dependent transcription in a time- and dose-dependent manner and we identify Inter-alpha-inhibitor (IalphaI) as a component in serum capable of activating the Yes/YAP/TEAD pathway | Serum Inter-α-inhibitor activates the Yes tyrosine kinase and YAP/TEAD transcriptional complex in mouse embryonic stem cells.
Pijuan-Galitó S, Tamm C, Annerén C., Free PMC Article | 02/14/2015 |
| Differentiation of embryonic stem cells is driven by c-Src is antagonized by c-Yes. | c-Yes tyrosine kinase is a potent suppressor of ES cell differentiation and antagonizes the actions of its closest phylogenetic relative, c-Src.
Zhang X, Meyn MA 3rd, Smithgall TE., Free PMC Article | 09/6/2014 |
| The antiapoptotic effect of YES1 activation in response to testicular heat insult may mediate via the regulation of extracellular signal-regulated kinase (ERK)/metastasis-associated 1 (MTA1) cascade. | YES1 activation elicited by heat stress is anti-apoptotic in mouse pachytene spermatocytes.
Liang Y, Dong Y, Zhao J, Li W. | 08/30/2014 |
| Results suggest that LKB1 inactivation in the context of RAS activation facilitates metastasis by inducing an SFK-dependent expansion of a prometastatic, CD24(+) tumor subpopulation. | LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.
Liu W, Monahan KB, Pfefferle AD, Shimamura T, Sorrentino J, Chan KT, Roadcap DW, Ollila DW, Thomas NE, Castrillon DH, Miller CR, Perou CM, Wong KK, Bear JE, Sharpless NE., Free PMC Article | 09/1/2012 |
| YAP, TEAD2 and Yes are highly expressed in self-renewing embryonic stem cells, and are activated by LIF. | Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF.
Tamm C, Böwer N, Annerén C. | 07/23/2011 |
| Binding of CD95 Ligand to CD95 on glioblastoma cells recruit Yes and the p85 subunit of phosphatidylinositol 3-kinase to CD95, which signal invasion via the glycogen synthase kinase 3-beta pathway and subsequent expression of matrix metalloproteinases. | Yes and PI3K bind CD95 to signal invasion of glioblastoma.
Kleber S, Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O, Thiemann M, Mueller W, Sykora J, Kuhn A, Schreglmann N, Letellier E, Zuliani C, Klussmann S, Teodorczyk M, Gröne HJ, Ganten TM, Sültmann H, Tüttenberg J, von Deimling A, Regnier-Vigouroux A, Herold-Mende C, Martin-Villalba A. | 01/21/2010 |
| Data imply that distinct modes of spatial activation and membrane delivery, under the control of specific acylation attachment sequences and endosome sub-type requirements, define distinct properties of the three SFKs (Src family kinases). | The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements.
Sandilands E, Brunton VG, Frame MC. | 01/21/2010 |
| Data show that in response to angiotensin II, the ability of ERK1/2 to remain within the cytoplasm or translocate into the nucleus is controlled by c-Src/Yes/Fyn or heterotrimeric G protein/PKCzeta signaling, respectively. | ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCzeta-controlled ERK1/2 activity within the nucleus.
Godeny MD, Sayeski PP. | 01/21/2010 |
| eIF4E and yes have cooperative roles in oncogenic transformation | Translational upregulation of yes accompanies eIF4E-mediated oncogenic transformation.
Defatta RJ, De Benedetti A. | 01/21/2010 |