FGFR3 alterations in bladder cancer: Sensitivity and resistance to targeted therapies. | FGFR3 alterations in bladder cancer: Sensitivity and resistance to targeted therapies. Noeraparast M, Krajina K, Pichler R, Niedersüß-Beke D, Shariat SF, Grünwald V, Ahyai S, Pichler M., Free PMC Article | 10/25/2024 |
Muscle-Invasive Bladder Cancer With Hydronephrosis Exhibits a High Frequency of Mutations in Fibroblast Growth Factor Receptor 3 Gene. | Muscle-Invasive Bladder Cancer With Hydronephrosis Exhibits a High Frequency of Mutations in Fibroblast Growth Factor Receptor 3 Gene. Kobatake K, Ikeda K, Kohada Y, Tasaka R, Takemoto K, Fukushima T, Miyamoto S, Sekino Y, Kitano H, Goto K, Hieda K, Goriki A, Hayashi T, Hinata N. | 05/29/2024 |
[Clinical characteristics and prognosis of newly diagnosed multiple myeloma patients with FGFR3 gene mutations]. | [Clinical characteristics and prognosis of newly diagnosed multiple myeloma patients with FGFR3 gene mutations]. Shen N, Zhang J, Xia Y, Shen XX, Wang J, Jin YY, Zhang R, Li JY, Chen LJ., Free PMC Article | 03/21/2024 |
Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts. | Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts. Bahlinger V, Branz A, Strissel PL, Strick R, Lange F, Geppert CI, Klümper N, Hölzel M, Wach S, Taubert H, Sikic D, Wullich B, Angeloni M, Ferrazzi F, Diehl L, Kovalenko M, Elboudwarej E, Jürgensmeier JM, Hartmann A, Eckstein M. | 03/6/2024 |
Exploring FGFR3 Mutations in the Male Germline: Implications for Clonal Germline Expansions and Paternal Age-Related Dysplasias. | Exploring FGFR3 Mutations in the Male Germline: Implications for Clonal Germline Expansions and Paternal Age-Related Dysplasias. Moura S, Hartl I, Brumovska V, Calabrese PP, Yasari A, Striedner Y, Bishara M, Mair T, Ebner T, Schütz GJ, Sevcsik E, Tiemann-Boege I., Free PMC Article | 02/28/2024 |
N-glycan on N262 of FGFR3 regulates the intracellular localization and phosphorylation of the receptor. | N-glycan on N262 of FGFR3 regulates the intracellular localization and phosphorylation of the receptor. Hashimoto U, Fujitani N, Uehara Y, Okamoto H, Saitou A, Ito F, Ariki S, Shiratsuchi A, Hasegawa Y, Takahashi M. | 02/24/2024 |
Non-Small Cell Lung Carcinoma With Clear Cell Features and FGFR3::TACC3 Gene Rearrangement : Clinicopathologic and Next Generation Sequencing Study of 7 Cases. | Non-Small Cell Lung Carcinoma With Clear Cell Features and FGFR3::TACC3 Gene Rearrangement : Clinicopathologic and Next Generation Sequencing Study of 7 Cases. Suster D, Mackinnon AC, Ronen N, Mejbel HA, Harada S, Suster S. | 02/22/2024 |
FGFR3 Alterations in Bladder Cancer Stimulate Serine Synthesis to Induce Immune-Inert Macrophages That Suppress T-cell Recruitment and Activation. | FGFR3 Alterations in Bladder Cancer Stimulate Serine Synthesis to Induce Immune-Inert Macrophages That Suppress T-cell Recruitment and Activation. Ouyang Y, Ou Z, Zhong W, Yang J, Fu S, Ouyang N, Chen J, Xu L, Wu D, Qian J, Lin Y, Lin T, Huang J., Free PMC Article | 01/3/2024 |
Unravelling the pathogenesis of foramen magnum stenosis in patients with severe achondroplasia: a CT-based comparison with age-matched controls and FGFR3 craniosynostosis syndromes. | Unravelling the pathogenesis of foramen magnum stenosis in patients with severe achondroplasia: a CT-based comparison with age-matched controls and FGFR3 craniosynostosis syndromes. Zhang CH, D'Arco F, Borghi A, Picariello S, Cheung M, Irving M, Thompson D. | 12/1/2023 |
Genome-wide open reading frame profiling identifies fibroblast growth factor signaling as a driver of PD-L1 expression in head and neck squamous cell carcinoma. | Genome-wide open reading frame profiling identifies fibroblast growth factor signaling as a driver of PD-L1 expression in head and neck squamous cell carcinoma. Mann JE, Smith JD, Kulkarni A, Foltin SK, Scheftz EB, Murray IR, Gensterblum-Miller E, Brummel CV, Bhangale A, Hoesli RC, Brenner JC., Free PMC Article | 11/3/2023 |
Fibroblast growth factor receptor 3 mutation attenuates response to immune checkpoint blockade in metastatic urothelial carcinoma by driving immunosuppressive microenvironment. | Fibroblast growth factor receptor 3 mutation attenuates response to immune checkpoint blockade in metastatic urothelial carcinoma by driving immunosuppressive microenvironment. Song Y, Peng Y, Qin C, Wang Y, Yang W, Du Y, Xu T., Free PMC Article | 10/10/2023 |
The Association of P53, CK29, and FGFR3 Overexpression with the Characteristics of Urothelial Cell Carcinoma of the Bladder. | P53, CK20, and FGFR3 Overexpression is Associated with the Characteristics of Urothelial Cell Carcinoma of the Bladder. Asgari M, Firouzi F, Abolhasani M, Bahadoram M, Barahman M, Madjd Z, Mehrazam M, Hassanzadeh S, Akade E., Free PMC Article | 10/5/2023 |
KLF2 regulates stemness of human mesenchymal stem cells by targeting FGFR3. | KLF2 regulates stemness of human mesenchymal stem cells by targeting FGFR3. Gong Z, Shu Z, Zhou Y, Chen Y, Zhu H. | 09/29/2023 |
FGFR3 mutation characterization identifies prognostic and immune-related gene signatures in bladder cancer. | FGFR3 mutation characterization identifies prognostic and immune-related gene signatures in bladder cancer. Xu PH, Chen S, Wang Y, Jin S, Wang J, Ye D, Zhu X, Shen Y. | 08/28/2023 |
Frequent Telomerase Reverse Transcriptase Promoter and Fibroblast Growth Factor Receptor 3 Mutations Support the Precursor Nature of Papillary Urothelial Hyperplasia of the Urinary Bladder. | Frequent Telomerase Reverse Transcriptase Promoter and Fibroblast Growth Factor Receptor 3 Mutations Support the Precursor Nature of Papillary Urothelial Hyperplasia of the Urinary Bladder. Cheng L, Lopez-Beltran A, Wang M, Whaley RD, De Souza A, Au S, Ge R, Cimadamore A, Amin A, Golijanin B, MacLennan GT, Osunkoya AO, Montironi R, Zhang S. | 07/31/2023 |
Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway. | Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway. Zhang H, Xiang G, Li J, He S, Wang Y, Deng A, Wang Y, Guo C., Free PMC Article | 06/23/2023 |
Autoantibodies Against Trisulfated Heparin Disaccharide and Fibroblast Growth Factor Receptor-3 May Play a Role in the Pathogenesis of Neuropathic Corneal Pain. | Autoantibodies Against Trisulfated Heparin Disaccharide and Fibroblast Growth Factor Receptor-3 May Play a Role in the Pathogenesis of Neuropathic Corneal Pain. Bayraktutar BN, Atocha V, Farhad K, Soto O, Hamrah P., Free PMC Article | 06/13/2023 |
Familial isolated acanthosis nigricans as a result of a recurrent FGFR3 truncating mutation. | Familial isolated acanthosis nigricans as a result of a recurrent FGFR3 truncating mutation. Pesqué D, March-Rodriguez Á, Abreu-Rodríguez I, Pérez-Jurado LA, Pujol RM. | 06/8/2023 |
[Investigation of the mutational status of the FGFR3 gene in urothelial bladder carcinoma]. | [Investigation of the mutational status of the FGFR3 gene in urothelial bladder carcinoma]. Oliushina EM, Zavalishina LE, Alekseenok EY, Oskina NA, Andreeva YY, Kuznetsova OA, Filipenko ML, Frank GA. | 04/17/2023 |
P4HA2-mediated HIF-1alpha stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer. | P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer. Li X, Li Y, Liu B, Chen L, Lyu F, Zhang P, He Q, Cheng L, Liu C, Song Y, Xing Y. | 03/27/2023 |
PRMT5/FGFR3/AKT Signaling Axis Facilitates Lung Cancer Cell Metastasis. | PRMT5/FGFR3/AKT Signaling Axis Facilitates Lung Cancer Cell Metastasis. Zheng Y, Lu J, Hu X, Hu X, Gao X, Zhou J., Free PMC Article | 03/20/2023 |
FGFR3 Mutation Status and FGFR3 Expression in a Large Bladder Cancer Cohort Treated by Radical Cystectomy: Implications for Anti-FGFR3 Treatment? | FGFR3 Mutation Status and FGFR3 Expression in a Large Bladder Cancer Cohort Treated by Radical Cystectomy: Implications for Anti-FGFR3 Treatment?(†). van Rhijn BWG, Mertens LS, Mayr R, Bostrom PJ, Real FX, Zwarthoff EC, Boormans JL, Abas C, van Leenders GJLH, Götz S, Hippe K, Bertz S, Neuzillet Y, Sanders J, Broeks A, van der Heijden MS, Jewett MAS, Marquez M, Stoehr R, Zlotta AR, Eckstein M, Soorojebally Y, Roshani H, Burger M, Otto W, Radvanyi F, Sirab N, Pouessel D, Wullich B, van der Kwast TH, Malats N, Hartmann A, Allory Y, Zuiverloon TCM. | 02/22/2023 |
Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability. | Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability. Wang CG, Peiris MN, Meyer AN, Nelson KN, Donoghue DJ., Free PMC Article | 02/16/2023 |
Infiltrating gliomas with FGFR alterations: Histologic features, genetic alterations, and potential clinical implications. | Infiltrating gliomas with FGFR alterations: Histologic features, genetic alterations, and potential clinical implications. Dono A, El Achi H, Bundrant BE, Goli PS, Zhu P, Ozkizilkaya HI, Esquenazi Y, Ballester LY. | 02/15/2023 |
Genetic Interference of FGFR3 Impedes Invasion of Upper Tract Urothelial Carcinoma Cells by Alleviating RAS/MAPK Signal Activity. | Genetic Interference of FGFR3 Impedes Invasion of Upper Tract Urothelial Carcinoma Cells by Alleviating RAS/MAPK Signal Activity. Huang GK, Huang CC, Kang CH, Cheng YT, Tsai PC, Kao YH, Chung YH., Free PMC Article | 01/28/2023 |