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    FGF7 fibroblast growth factor 7 [ Homo sapiens (human) ]

    Gene ID: 2252, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Primer on fibroblast growth factor 7 (FGF 7).

    Primer on fibroblast growth factor 7 (FGF 7).
    Zheng Y, Liu WH, Yang B, Milman Krentsis I.

    09/19/2024
    FGF7 and FGF10 Promote Fate Transition of Human Epidermal Cell-derived Organoids to an Eccrine Gland Phenotype.

    FGF7 and FGF10 Promote Fate Transition of Human Epidermal Cell-derived Organoids to an Eccrine Gland Phenotype.
    Zhao J, Zhang L, Zhang Y, Cao M, Wang C, Hu A, Cao L, Luo Q, You Z, Ma X, Gong L, Zhang C, Li H., Free PMC Article

    09/17/2024
    FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection.

    FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection.
    Meng H, Liao Z, Ji Y, Wang D, Han Y, Huang C, Hu X, Chen J, Zhang H, Li Z, Wang C, Sun H, Sun J, Chen L, Yin J, Zhao J, Xu T, Liu H., Free PMC Article

    05/14/2024
    Hepatocyte survival and proliferation by fibroblast growth factor 7 attenuates liver inflammation, and fibrogenesis during acute liver injury via paracrine mechanisms.

    Hepatocyte survival and proliferation by fibroblast growth factor 7 attenuates liver inflammation, and fibrogenesis during acute liver injury via paracrine mechanisms.
    Geervliet E, Terstappen LWMM, Bansal R.

    11/1/2023
    Upregulation of FGF7 Induced Intravesical Prostatic Protrusion of Benign Prostatic Hyperplasia via the ERK1/2 Signaling Pathway.

    Upregulation of FGF7 Induced Intravesical Prostatic Protrusion of Benign Prostatic Hyperplasia via the ERK1/2 Signaling Pathway.
    Zhou Z, Wu L, Zhao S, Xia SJ, Pan L, Chen M, Zhu YP, Jiang JT, Shi F.

    06/2/2023
    Down-Regulation of circCOL1A2 Suppresses the Dysfunction of Diabetes-Related Retinal Microvascular Endothelial Cells via miR-646/FGF7 Axis.

    Down-Regulation of circCOL1A2 Suppresses the Dysfunction of Diabetes-Related Retinal Microvascular Endothelial Cells via miR-646/FGF7 Axis.
    Cao H, Xu X, Wang K, Li C.

    10/22/2022
    Genotyping Helicobacter pylori and fgf7 gene expression in gastric cancer.

    Genotyping Helicobacter pylori and fgf7 gene expression in gastric cancer.
    Hedayati MA, Khani D, Bashiri H.

    09/24/2022
    FGF7/FGFR2-JunB signalling counteracts the effect of progesterone in luminal breast cancer.

    FGF7/FGFR2-JunB signalling counteracts the effect of progesterone in luminal breast cancer.
    Mieczkowski K, Kitowska K, Braun M, Galikowska-Bogut B, Gorska-Arcisz M, Piasecka D, Stawiski K, Zaczek AJ, Nejc D, Kordek R, Romanska HM, Sadej R., Free PMC Article

    08/13/2022
    Cell-subpopulation alteration and FGF7 activation regulate the function of tendon stem/progenitor cells in 3D microenvironment revealed by single-cell analysis.

    Cell-subpopulation alteration and FGF7 activation regulate the function of tendon stem/progenitor cells in 3D microenvironment revealed by single-cell analysis.
    Zhang H, Chen Y, Fan C, Liu R, Huang J, Zhang Y, Tang C, Zhou B, Chen X, Ju W, Zhao Y, Han J, Wu P, Zhang S, Shen W, Yin Z, Chen X, Ouyang H.

    03/26/2022
    Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.

    Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
    Hu H, Piotrowska Z, Hare PJ, Chen H, Mulvey HE, Mayfield A, Noeen S, Kattermann K, Greenberg M, Williams A, Riley AK, Wilson JJ, Mao YQ, Huang RP, Banwait MK, Ho J, Crowther GS, Hariri LP, Heist RS, Kodack DP, Pinello L, Shaw AT, Mino-Kenudson M, Hata AN, Sequist LV, Benes CH, Niederst MJ, Engelman JA., Free PMC Article

    01/8/2022
    Keratinocyte growth factor in focus: A comprehensive review from structural and functional aspects to therapeutic applications of palifermin.

    Keratinocyte growth factor in focus: A comprehensive review from structural and functional aspects to therapeutic applications of palifermin.
    Sadeghi S, Kalhor H, Panahi M, Abolhasani H, Rahimi B, Kalhor R, Mehrabi A, Vahdatinia M, Rahimi H.

    01/1/2022
    Exosome-transmitted circ-CARD6 facilitates posterior capsule opacification development by miR-31/FGF7 axis.

    Exosome-transmitted circ-CARD6 facilitates posterior capsule opacification development by miR-31/FGF7 axis.
    Liu Y, Chen T, Zheng G.

    09/18/2021
    The proliferative and anti-apoptosis functions of KGF/KGFR contributes to bronchial epithelial repair in asthma.

    The proliferative and anti-apoptosis functions of KGF/KGFR contributes to bronchial epithelial repair in asthma.
    Wang J, Sun H, Liu Y.

    09/4/2021
    LncRNA BCRT1 facilitates osteosarcoma progression via regulating miR-1303/FGF7 axis.

    LncRNA BCRT1 facilitates osteosarcoma progression via regulating miR-1303/FGF7 axis.
    Han G, Guo Q, Ma N, Bi W, Xu M, Jia J, Wang W., Free PMC Article

    07/24/2021
    [Expression of serous fibroblast growth factor 7 and related inflammatory factors in patients with acute exacerbation of chronic obstructive pulmonary disease].

    [Expression of serous fibroblast growth factor 7 and related inflammatory factors in patients with acute exacerbation of chronic obstructive pulmonary disease].
    Wan Q, Guo Z, Caikai S, Wei Q, Jia W, Luo X, Yang T, Shi Y, Gu X, Xu S.

    06/5/2021
    Hyperphosphatemia with low FGF7 and normal FGF23 and sFRP4 levels in the circulation characterizes pediatric hypophosphatasia.

    Hyperphosphatemia with low FGF7 and normal FGF23 and sFRP4 levels in the circulation characterizes pediatric hypophosphatasia.
    Whyte MP, Zhang F, Wenkert D, Mumm S, Berndt TJ, Kumar R., Free PMC Article

    05/22/2021
    Mechanism of FGF7 gene silencing in regulating viability, apoptosis, invasion of retinoblastoma cell line HXO-Rb44 and angiogenesis.

    Mechanism of FGF7 gene silencing in regulating viability, apoptosis, invasion of retinoblastoma cell line HXO-Rb44 and angiogenesis.
    Chen WJ, Sun CX, Li W.

    04/3/2021
    Cyclodextrin inclusion complex inhibits circulating galectin-3 and FGF-7 and affects the reproductive integrity and mobility of Caco-2 cells.

    Cyclodextrin inclusion complex inhibits circulating galectin-3 and FGF-7 and affects the reproductive integrity and mobility of Caco-2 cells.
    Maki MAA, Cheah SC, Bayazeid O, Kumar PV., Free PMC Article

    03/13/2021
    Long Noncoding RNA AFAP1-AS1 Promotes Cell Proliferation and Metastasis via the miR-155-5p/FGF7 Axis and Predicts Poor Prognosis in Gastric Cancer.

    Long Noncoding RNA AFAP1-AS1 Promotes Cell Proliferation and Metastasis via the miR-155-5p/FGF7 Axis and Predicts Poor Prognosis in Gastric Cancer.
    Ma HW, Xi DY, Ma JZ, Guo M, Ma L, Ma DH, Li PW, Guo CA., Free PMC Article

    10/10/2020
    findings illustrate a role for miR-455-3p-1 in modulating FGF7-RAS/ERK signaling and suggest that an agomir of miR-455-3p-1 could inhibit the proliferation of PASMCs and mitigate PAH in vivo.

    Mir-455-3p-1 represses FGF7 expression to inhibit pulmonary arterial hypertension through inhibiting the RAS/ERK signaling pathway.
    Zhou C, Chen Y, Kang W, Lv H, Fang Z, Yan F, Li L, Zhang W, Shi J.

    06/20/2020
    MiR-381-3p was lowly expressed while FGF7 was highly expressed in cervical cancer cells. This study validated a direct target relationship and a negative correlation between miR-381-3p and FGF7.

    miR-381-3p restrains cervical cancer progression by downregulating FGF7.
    Shang A, Zhou C, Bian G, Chen W, Lu W, Wang W, Li D.

    02/29/2020
    These results indicate that FGF-7 induces TNF-alpha expression in HaCaT cells.

    FGF-7 facilitates the process of psoriasis by inducing TNF-α expression in HaCaT cells.
    Pu J, Wang R, Zhang G, Wang J.

    02/8/2020
    Panning against the purified FGF7 was performed, and the identified single-domain antibodies showed significant affinity.

    Identification of Novel Single-Domain Antibodies against FGF7 Using Phage Display Technology.
    Jafari B, Hamzeh-Mivehroud M, Moosavi-Movahedi AA, Dastmalchi S.

    09/14/2019
    Study assessed genetic association of FGF7 variant rs12905203 in a new established-COPD cohort in Chinese Han, and identified a functional variant that modulates the gene expression of FGF7 through the regulation of AP-1 binding.

    A functional variant alters binding of activating protein 1 regulating expression of FGF7 gene associated with chronic obstructive pulmonary disease.
    Zhang X, Guo Y, Yang J, Niu J, Du L, Li H, Li X., Free PMC Article

    08/24/2019
    the expression levels of FGF7, FGF10, and FGFR2 were lower in IPF lung regions undergoing active remodeling, and inversely correlated with Idiopathic pulmonary arterial hypertension severity, indicating that increased expression might reflect lung repair rather than lung pathology, and warranting further research on the precise role of FGF signaling in pulmonary parenchymal and vascular remodeling.

    Is the fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling?
    El Agha E, Schwind F, Ruppert C, Günther A, Bellusci S, Schermuly RT, Kosanovic D.

    07/6/2019
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