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    FGA fibrinogen alpha chain [ Homo sapiens (human) ]

    Gene ID: 2243, updated on 19-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Fibrinogen Aalpha gene genotyping in patients with inherited afibrinogenemia deficiency; a novel mutation in Iranian afibrinogenemia patients.

    Fibrinogen Aα gene genotyping in patients with inherited afibrinogenemia deficiency; a novel mutation in Iranian afibrinogenemia patients.
    Moazzeni A, Naderi M, Dorgalaleh A, Alizadeh S.

    03/19/2024
    [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene].

    [Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene].
    Shao X, Ma J, Wang Z, Sun M, Huang Z, Jiang Z, Liu X, Li S, Liu Y.

    12/18/2023
    Two Novel Heterozygous Mutations (p.gammaPhe230Val and p.AalphaAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families.

    Two Novel Heterozygous Mutations (p.γPhe230Val and p.AαAsn839Thr) Cause Hereditary Hypodysfibrinogenemia in Two Chinese Independent Families.
    Ge S, Luo Y, Dong R, Guo X, Wang M, Chen Y.

    06/13/2023
    Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients.

    Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients.
    Maslow A, Cheves T, Joyce MF, Apruzzese P, Sweeney J.

    05/8/2023
    Fibrinogen-Aalpha THR312ALA Polymorphism is Associated to Chronic Thromboembolic Pulmonary Hypertension in Turkey.

    Fibrinogen-Aα THR312ALA Polymorphism is Associated to Chronic Thromboembolic Pulmonary Hypertension in Turkey.
    Çörtük M, Yıldızeli B, Kurar E, Kayış SA, Tanrıverdi E, Çetinkaya E., Free PMC Article

    03/6/2023
    FGA Controls VEGFA Secretion to Promote Angiogenesis by Activating the VEGFR2-FAK Signalling Pathway.

    FGA Controls VEGFA Secretion to Promote Angiogenesis by Activating the VEGFR2-FAK Signalling Pathway.
    Li H, Cai E, Cheng H, Ye X, Ma R, Zhu H, Chang X., Free PMC Article

    05/7/2022
    An association between fibrinogen gene polymorphisms and diabetic peripheral neuropathy in young patients with type 1 diabetes.

    An association between fibrinogen gene polymorphisms and diabetic peripheral neuropathy in young patients with type 1 diabetes.
    Vojtková J, Kolková Z, Motyková K, Kostková M, Suroviaková S, Grendár M, Bánovčin P.

    01/1/2022
    Fibrinogen and Antifibrinolytic Proteins: Interactions and Future Therapeutics.

    Fibrinogen and Antifibrinolytic Proteins: Interactions and Future Therapeutics.
    Pechlivani N, Kearney KJ, Ajjan RA., Free PMC Article

    12/18/2021
    Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.

    Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.
    Padilla-Godínez FJ, Ramos-Acevedo R, Martínez-Becerril HA, Bernal-Conde LD, Garrido-Figueroa JF, Hiriart M, Hernández-López A, Argüero-Sánchez R, Callea F, Guerra-Crespo M., Free PMC Article

    12/18/2021
    Afibrinogenemia with two compound heterozygous mutations in FGA gene.

    Afibrinogenemia with two compound heterozygous mutations in FGA gene.
    Feugray G, Billoir P, Casini A, Neerman-Arbez M, Barbay V, Chamouni P, Schneider P, Le Cam Duchez V.

    10/23/2021
    Osteoclasts degrade fibrinogen scaffolds and induce mesenchymal stem/stromal osteogenic differentiation.

    Osteoclasts degrade fibrinogen scaffolds and induce mesenchymal stem/stromal osteogenic differentiation.
    Almeida AR, Bessa-Gonçalves M, Vasconcelos DM, Barbosa MA, Santos SG.

    10/2/2021
    Analysis of an Inherited Dysfibrinogenemia Pedigree Associated with a Heterozygous Mutation in the FGA Gene.

    Analysis of an Inherited Dysfibrinogenemia Pedigree Associated with a Heterozygous Mutation in the FGA Gene.
    Li S, Wang M, Li X, Xu Q, Liu S, Luo S, Chen Y.

    08/14/2021
    Identification of a novel mutation in congenital afibrinogenemia in Iranian patients.

    Identification of a novel mutation in congenital afibrinogenemia in Iranian patients.
    Nojehdeh ST, Mojbafan M, Masoodifard M, Amini M, Zeinali S.

    07/17/2021
    Identification and expression of a novel heterozygous frameshift mutation in FGA accounting for congenital hypofibrinogenemia in carriers of severe hemophilia A.

    Identification and expression of a novel heterozygous frameshift mutation in FGA accounting for congenital hypofibrinogenemia in carriers of severe hemophilia A.
    Vilar R, Casini A, Fournel A, Mourey G, Neerman-Arbez M.

    07/3/2021
    Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders.

    Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders.
    Zhou P, Yu M, Peng Y, Ma P, Wan L.

    07/3/2021
    Fibrinogen Alpha Chain Knockout Promotes Tumor Growth and Metastasis through Integrin-AKT Signaling Pathway in Lung Cancer.

    Fibrinogen Alpha Chain Knockout Promotes Tumor Growth and Metastasis through Integrin-AKT Signaling Pathway in Lung Cancer.
    Wang M, Zhang G, Zhang Y, Cui X, Wang S, Gao S, Wang Y, Liu Y, Bae JH, Yang WH, Qi LS, Wang L, Liu R.

    07/3/2021
    Serum sCD14, PGLYRP2 and FGA as potential biomarkers for multidrug-resistant tuberculosis based on data-independent acquisition and targeted proteomics.

    Serum sCD14, PGLYRP2 and FGA as potential biomarkers for multidrug-resistant tuberculosis based on data-independent acquisition and targeted proteomics.
    Chen J, Han YS, Yi WJ, Huang H, Li ZB, Shi LY, Wei LL, Yu Y, Jiang TT, Li JC., Free PMC Article

    05/8/2021
    GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen alphaC-Region.

    GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen αC-Region.
    Xu RG, Gauer JS, Baker SR, Slater A, Martin EM, McPherson HR, Duval C, Manfield IW, Bonna AM, Watson SP, Ariëns RAS., Free PMC Article

    03/20/2021
    Relation of alpha2-Antiplasmin Genotype and Genetic Determinants of Fibrinogen Synthesis and Fibrin Clot Formation with Vascular Endothelial Growth Factor Level in Axial Spondyloarthritis.

    Relation of α(2)-Antiplasmin Genotype and Genetic Determinants of Fibrinogen Synthesis and Fibrin Clot Formation with Vascular Endothelial Growth Factor Level in Axial Spondyloarthritis.
    Hoppe B, Schwedler C, Haibel H, Verba M, Proft F, Protopopov M, Heuft HG, Rios Rodriguez V, Edelmann A, Rudwaleit M, Sieper J, Poddubnyy D., Free PMC Article

    03/6/2021
    Evaluation of lipoprotein-associated phospholipase A2, serum amyloid A, and fibrinogen as diagnostic biomarkers for patients with acute cerebral infarction.

    Evaluation of lipoprotein-associated phospholipase A2, serum amyloid A, and fibrinogen as diagnostic biomarkers for patients with acute cerebral infarction.
    Tao L, ShiChuan W, DeTai Z, Lihua H., Free PMC Article

    12/19/2020
    Quantitative Serum Proteomic Study Reveals that Fibrinogen-Related Proteins May Participate in the Pathophysiological Process of Simple Febrile Convulsion.

    Quantitative Serum Proteomic Study Reveals that Fibrinogen-Related Proteins May Participate in the Pathophysiological Process of Simple Febrile Convulsion.
    Li C, Zhao X, Zhao Y, Liu X, Zhang J, Li S, Zhou Z, Yin Y, Ma W, Wang H.

    12/5/2020
    Preoperative Serum Fibrinogen is Associated With Acute Kidney Injury after Cardiac Valve Replacement Surgery.

    Preoperative Serum Fibrinogen is Associated With Acute Kidney Injury after Cardiac Valve Replacement Surgery.
    Yang JJ, Lei WH, Hu P, Wu BB, Chen JX, Ni YM, Lai EY, Han F, Chen JH, Yang Y., Free PMC Article

    11/28/2020
    Combination of preoperative fibrinogen and neutrophil to lymphocyte ratio is a predictive prognostic factor in ESCC and AEG systematic review.

    Combination of preoperative fibrinogen and neutrophil to lymphocyte ratio is a predictive prognostic factor in ESCC and AEG systematic review.
    Tianxing G, Xiaojie P, Lihuan Z, Yangyun H., Free PMC Article

    10/3/2020
    High D-dimer levels are associated with prostate cancer.

    High D-dimer levels are associated with prostate cancer.
    Kalkan S, Caliskan S.

    09/19/2020
    Fibrinogen alpha chain is up-regulated and affects the pathogenesis of endometriosis.

    Fibrinogen alpha chain is up-regulated and affects the pathogenesis of endometriosis.
    Chen Y, Li H, Cheng HY, Rui-Qiong M, Ye X, Cui H, Hong-Lan Z, Chang XH.

    08/29/2020
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