| BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer. | BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer.
Chehade H, Gogoi R, Adzibolosu NK, Galoforo S, Fehmi RA, Kheil M, Fox A, Kim S, Rattan R, Hou Z, Morris RT, Matherly LH, Mor G, Alvero AB., Free PMC Article | 09/20/2024 |
| RIPK4 downregulation impairs Wnt3A-stimulated invasiveness via Wnt/beta-catenin signaling in melanoma cells and tumor growth in vivo. | RIPK4 downregulation impairs Wnt3A-stimulated invasiveness via Wnt/β-catenin signaling in melanoma cells and tumor growth in vivo.
Wronski N, Madej E, Grabacka M, Brożyna AA, Wolnicka-Glubisz A. | 12/5/2023 |
| Abnormal activation of the Wnt3a/beta-catenin signaling pathway promotes the expression of T-box transcription factor 3(TBX3) and the epithelial-mesenchymal transition pathway to mediate the occurrence of adenomyosis. | Abnormal activation of the Wnt3a/β-catenin signaling pathway promotes the expression of T-box transcription factor 3(TBX3) and the epithelial-mesenchymal transition pathway to mediate the occurrence of adenomyosis.
Li M, Li T, Jin T, Chen Y, Cheng L, Liang Q, Yan S, Li T, Ran Q, Chen W. | 11/30/2023 |
| PDLIM1 inhibits cell migration and invasion in diabetic retinopathy via negatively regulating Wnt3a. | PDLIM1 inhibits cell migration and invasion in diabetic retinopathy via negatively regulating Wnt3a.
Xie P, You Q, Zhu J, Xie W, Wei P, Zhu S, Du Y, Gao X., Free PMC Article | 04/12/2023 |
| Wnt3a/YTHDF1 Regulated Oxaliplatin-Induced Neuropathic Pain Via TNF-alpha/IL-18 Expression in the Spinal Cord. | Wnt3a/YTHDF1 Regulated Oxaliplatin-Induced Neuropathic Pain Via TNF-α/IL-18 Expression in the Spinal Cord.
Bai X, Huang Y, Huang W, Zhang Y, Zhang K, Li Y, Ouyang H. | 04/10/2023 |
| Colonic healing requires Wnt produced by epithelium as well as Tagln+ and Acta2+ stromal cells. | Colonic healing requires Wnt produced by epithelium as well as Tagln+ and Acta2+ stromal cells.
Das S, Feng Q, Balasubramanian I, Lin X, Liu H, Pellón-Cardenas O, Yu S, Zhang X, Liu Y, Wei Z, Bonder EM, Verzi MP, Hsu W, Zhang L, Wang TC, Gao N., Free PMC Article | 02/12/2022 |
| WNT3A-loaded exosomes enable cartilage repair. | WNT3A-loaded exosomes enable cartilage repair.
Thomas BL, Eldridge SE, Nosrati B, Alvarez M, Thorup AS, Nalesso G, Caxaria S, Barawi A, Nicholson JG, Perretti M, Gaston-Massuet C, Pitzalis C, Maloney A, Moore A, Jupp R, Dell'Accio F., Free PMC Article | 01/22/2022 |
| Noncanonical Wnt Signaling Promotes Myofibroblast Differentiation in Pulmonary Fibrosis. | Noncanonical Wnt Signaling Promotes Myofibroblast Differentiation in Pulmonary Fibrosis.
Liu T, Gonzalez De Los Santos F, Hirsch M, Wu Z, Phan SH., Free PMC Article | 11/22/2021 |
| Joint single-cell multiomic analysis in Wnt3a induced asymmetric stem cell division. | Joint single-cell multiomic analysis in Wnt3a induced asymmetric stem cell division.
Sun Z, Tang Y, Zhang Y, Fang Y, Jia J, Zeng W, Fang D., Free PMC Article | 11/6/2021 |
| Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration. | Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration.
Ankawa R, Goldberger N, Yosefzon Y, Koren E, Yusupova M, Rosner D, Feldman A, Baror-Sebban S, Buganim Y, Simon DJ, Tessier-Lavigne M, Fuchs Y. | 10/23/2021 |
| Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division. | Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division.
Junyent S, Reeves JC, Szczerkowski J, Garcin CL, Trieu TJ, Wilson M, Lundie-Brown J, Habib SJ., Free PMC Article | 10/23/2021 |
| FKBP8 variants are risk factors for spina bifida. | FKBP8 variants are risk factors for spina bifida.
Tian T, Cao X, Kim SE, Lin YL, Steele JW, Cabrera RM, Karki M, Yang W, Marini NJ, Hoffman EN, Han X, Hu C, Wang L, Wlodarczyk BJ, Shaw GM, Ren A, Finnell RH, Lei Y., Free PMC Article | 08/28/2021 |
| M2-like tumor-associated macrophages-secreted Wnt1 and Wnt3a promotes dedifferentiation and metastasis via activating beta-catenin pathway in thyroid cancer. | M2-like tumor-associated macrophages-secreted Wnt1 and Wnt3a promotes dedifferentiation and metastasis via activating β-catenin pathway in thyroid cancer.
Lv J, Feng ZP, Chen FK, Liu C, Jia L, Liu PJ, Yang CZ, Hou F, Deng ZY. | 02/20/2021 |
| Spinal Wnt5a Plays a Key Role in Spinal Dendritic Spine Remodeling in Neuropathic and Inflammatory Pain Models and in the Proalgesic Effects of Peripheral Wnt3a. | Spinal Wnt5a Plays a Key Role in Spinal Dendritic Spine Remodeling in Neuropathic and Inflammatory Pain Models and in the Proalgesic Effects of Peripheral Wnt3a.
Simonetti M, Kuner R., Free PMC Article | 01/2/2021 |
| Overexpressed microRNA-140 inhibits pulmonary fibrosis in interstitial lung disease via the Wnt signaling pathway by downregulating osteoglycin. | Overexpressed microRNA-140 inhibits pulmonary fibrosis in interstitial lung disease via the Wnt signaling pathway by downregulating osteoglycin.
Shi S, Li H. | 12/19/2020 |
| WNT3A Promotes Neuronal Regeneration upon Traumatic Brain Injury. | WNT3A Promotes Neuronal Regeneration upon Traumatic Brain Injury.
Chang CY, Liang MZ, Wu CC, Huang PY, Chen HI, Yet SF, Tsai JW, Kao CF, Chen L., Free PMC Article | 11/21/2020 |
| Dopamine D2 receptor modulates Wnt expression and control of cell proliferation. | Dopamine D(2) receptor modulates Wnt expression and control of cell proliferation.
Han F, Konkalmatt P, Mokashi C, Kumar M, Zhang Y, Ko A, Farino ZJ, Asico LD, Xu G, Gildea J, Zheng X, Felder RA, Lee REC, Jose PA, Freyberg Z, Armando I., Free PMC Article | 10/31/2020 |
| Vitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts. | Vitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts.
Ferrer-Mayorga G, Niell N, Cantero R, González-Sancho JM, Del Peso L, Muñoz A, Larriba MJ., Free PMC Article | 10/24/2020 |
| Findings show that Wnt3A Protein (Wnt3a) induces mitochondrial biogenesis through p38 mitogen-activated protein kinase/cAMP response element-binding protein (p38/CREB) pathway. | Wnt3a regulates mitochondrial biogenesis through p38/CREB pathway.
Ning X, He J, Shi X, Yu T, Yang G. | 07/11/2020 |
| TLR4 activation promotes Wnt3a-Dvl3 signaling. | TLR4 induced Wnt3a-Dvl3 restrains the intensity of inflammation and protects against endotoxin-driven organ failure through GSK3β/β-catenin signaling.
Yang D, Li S, Duan X, Ren J, Liang S, Yakoumatos L, Kang Y, Uriarte SM, Shang J, Li W, Wang H., Free PMC Article | 04/11/2020 |
| These results suggest that hotspot formation during early adipogenesis is related to cytoskeletal remodeling, which is regulated by the antagonistic action of GR and beta-catenin, and that Wnt3a reinforces beta-catenin function. | Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis.
Park B, Chang S, Lee GJ, Kang B, Kim JK, Park H., Free PMC Article | 02/29/2020 |
| This study shows that RGCs are direct cellular targets of Wnt3a-induced axonal growth, and we identified a novel association between Wnt signaling and Rip kinases in neurite formation. | Wnt signaling induces neurite outgrowth in mouse retinal ganglion cells.
Udeh A, Dvoriantchikova G, Carmy T, Ivanov D, Hackam AS. | 02/22/2020 |
| This study suggests that glutamine could protect against oxidative stress-induced injury in Alzheimer's disease (AD) mice via the Wnt3a/beta-catenin signaling pathway. | Glutamine Improves Oxidative Stress through the Wnt3a/β-Catenin Signaling Pathway in Alzheimer's Disease In Vitro and In Vivo.
Wang Y, Wang Q, Li J, Lu G, Liu Z., Free PMC Article | 11/16/2019 |
| the effect of morphological changes in Wnt-producing cells on intercellular signaling in the spinal cord, was examined. | Wnt produced by stretched roof-plate cells is required for the promotion of cell proliferation around the central canal of the spinal cord.
Shinozuka T, Takada R, Yoshida S, Yonemura S, Takada S. | 09/14/2019 |
| Gfi1b regulates the level of Wnt3a/beta-catenin signaling in hematopoietic stem cells and megakaryocytes. | Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.
Shooshtarizadeh P, Helness A, Vadnais C, Brouwer N, Beauchemin H, Chen R, Bagci H, Staal FJT, Coté JF, Möröy T., Free PMC Article | 04/6/2019 |