| Mechanical induction of osteoanabolic Wnt1 promotes osteoblast differentiation via Plat. | Mechanical induction of osteoanabolic Wnt1 promotes osteoblast differentiation via Plat.
Ahmad M, Haffner-Luntzer M, Schoppa A, Najafova Z, Lukic T, Yorgan TA, Amling M, Schinke T, Ignatius A. | 02/28/2024 |
| KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/beta-Catenin Signaling Pathway. | KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway.
Li Y, Wang Y, Zou Q, Li S, Zhang F. | 06/29/2023 |
| Early Wnt Signaling Activation Promotes Inner Ear Differentiation via Cell Caudalization in Mouse Stem Cell-Derived Organoids. | Early Wnt Signaling Activation Promotes Inner Ear Differentiation via Cell Caudalization in Mouse Stem Cell-Derived Organoids.
Tang PC, Chen L, Singh S, Groves AK, Koehler KR, Liu XZ, Nelson RF., Free PMC Article | 06/15/2023 |
| The protective effect of lncRNA NEAT1/miR-122-5p/Wnt1 axis on hippocampal damage in hepatic ischemic reperfusion young mice. | The protective effect of lncRNA NEAT1/miR-122-5p/Wnt1 axis on hippocampal damage in hepatic ischemic reperfusion young mice.
Dong Z, Jia L, Han W, Wang Y, Sheng M, Ren Y, Weng Y, Li H, Yu W. | 05/28/2023 |
| Wnt1 Boosts Fracture Healing by Enhancing Bone Formation in the Fracture Callus. | Wnt1 Boosts Fracture Healing by Enhancing Bone Formation in the Fracture Callus.
Haffner-Luntzer M, Ragipoglu D, Ahmad M, Schoppa A, Steppe L, Fischer V, Luther J, Yorgan T, Bockamp E, Amling M, Schinke T, Ignatius A. | 05/18/2023 |
| Mesenchymal cell-derived Wnt1 signaling regulates subchondral bone remodeling but has no effects on the development of growth plate or articular cartilage in mice. | Mesenchymal cell-derived Wnt1 signaling regulates subchondral bone remodeling but has no effects on the development of growth plate or articular cartilage in mice.
Wang F, Rummukainen P, Pehkonen M, Säämänen AM, Heino TJ, Kiviranta R. | 09/3/2022 |
| Wnt family member 1 (Wnt1) overexpression-induced M2 polarization of microglia alleviates inflammation-sensitized neonatal brain injuries. | Wnt family member 1 (Wnt1) overexpression-induced M2 polarization of microglia alleviates inflammation-sensitized neonatal brain injuries.
Gao J, Xu H, Rong Z, Chen L., Free PMC Article | 07/30/2022 |
| N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/beta-catenin signaling. | N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling.
Shi X, Cen Y, Shan L, Tian L, Zhu E, Yuan H, Li X, Liu Y, Wang B., Free PMC Article | 04/2/2022 |
| Cumulative inactivation of Nell-1 in Wnt1 expressing cell lineages results in craniofacial skeletal hypoplasia and postnatal hydrocephalus. | Cumulative inactivation of Nell-1 in Wnt1 expressing cell lineages results in craniofacial skeletal hypoplasia and postnatal hydrocephalus.
Chen X, Wang H, Yu M, Kim JK, Qi H, Ha P, Jiang W, Chen E, Luo X, Needle RB, Baik L, Yang C, Shi J, Kwak JH, Ting K, Zhang X, Soo C., Free PMC Article | 07/3/2021 |
| Osteoblastic Wnt1 regulates periosteal bone formation in adult mice. | Osteoblastic Wnt1 regulates periosteal bone formation in adult mice.
Wang F, Rummukainen P, Heino TJ, Kiviranta R. | 06/26/2021 |
| M2-like tumor-associated macrophages-secreted Wnt1 and Wnt3a promotes dedifferentiation and metastasis via activating beta-catenin pathway in thyroid cancer. | M2-like tumor-associated macrophages-secreted Wnt1 and Wnt3a promotes dedifferentiation and metastasis via activating β-catenin pathway in thyroid cancer.
Lv J, Feng ZP, Chen FK, Liu C, Jia L, Liu PJ, Yang CZ, Hou F, Deng ZY. | 02/20/2021 |
| The expression and regulation of Wnt1 in tooth movement-initiated mechanotransduction. | The expression and regulation of Wnt1 in tooth movement-initiated mechanotransduction.
Ei Hsu Hlaing E, Ishihara Y, Odagaki N, Wang Z, Ikegame M, Kamioka H. | 12/5/2020 |
| Long non-coding RNA MALAT1 sponges microRNA-429 to regulate apoptosis of hippocampal neurons in hypoxic-ischemic brain damage by regulating WNT1. | Long non-coding RNA MALAT1 sponges microRNA-429 to regulate apoptosis of hippocampal neurons in hypoxic-ischemic brain damage by regulating WNT1.
Fang H, Li HF, He MH, Yan JY, Yang M, Zhang FX, Wang RR, Wang QY, Zhang JP. | 08/15/2020 |
| loss of Lrp5, the co-receptor thought to transmit extracellular WNT signals during bone mass regulation, did not reduce the bone-anabolic effect of Wnt1, providing direct evidence that Wnt1 function does not require the LRP5 co-receptor. | Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
Luther J, Yorgan TA, Rolvien T, Ulsamer L, Koehne T, Liao N, Keller D, Vollersen N, Teufel S, Neven M, Peters S, Schweizer M, Trumpp A, Rosigkeit S, Bockamp E, Mundlos S, Kornak U, Oheim R, Amling M, Schinke T, David JP. | 11/9/2019 |
| the effect of morphological changes in Wnt-producing cells on intercellular signaling in the spinal cord, was examined. | Wnt produced by stretched roof-plate cells is required for the promotion of cell proliferation around the central canal of the spinal cord.
Shinozuka T, Takada R, Yoshida S, Yonemura S, Takada S. | 09/14/2019 |
| LBH plays an essential role in WNT-induced mammary tumorigenesis by promoting hyperplastic growth and tumor formation. | Loss of Limb-Bud-and-Heart (LBH) attenuates mammary hyperplasia and tumor development in MMTV-Wnt1 transgenic mice.
Ashad-Bishop K, Garikapati K, Lindley LE, Jorda M, Briegel KJ., Free PMC Article | 06/8/2019 |
| miR-34b/c modulates Wnt1 expression, promotes cell cycle exit, and induces dopaminergic differentiation. | miR-34b/c Regulates Wnt1 and Enhances Mesencephalic Dopaminergic Neuron Differentiation.
De Gregorio R, Pulcrano S, De Sanctis C, Volpicelli F, Guatteo E, von Oerthel L, Latagliata EC, Esposito R, Piscitelli RM, Perrone-Capano C, Costa V, Greco D, Puglisi-Allegra S, Smidt MP, di Porzio U, Caiazzo M, Mercuri NB, Li M, Bellenchi GC., Free PMC Article | 04/27/2019 |
| Major findings of the last decade document that Wnt/beta-catenin signaling in partnership with glial cells is critically involved in each step and at every level in the regulation of nigrostriatal dopaminergic neuronal health, protection, and regeneration in in the MPTP mouse model of Parkinson's disease. (Review) | Wnt/β-Catenin Signaling Pathway Governs a Full Program for Dopaminergic Neuron Survival, Neurorescue and Regeneration in the MPTP Mouse Model of Parkinson's Disease.
Marchetti B., Free PMC Article | 03/9/2019 |
| aberrant expression of AF1q may activate Wnt/beta-catenin signaling and result in podocyte injury. | AF1q Contributes to Adriamycin-Induced Podocyte Injury by Activating Wnt/β-Catenin Signaling.
Zhang H, Ren R, Du J, Sun T, Wang P, Kang P. | 09/1/2018 |
| Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system | Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system.
Dong L, Hao H, Liu J, Tong C, Ti D, Chen D, Chen L, Li M, Liu H, Fu X, Han W. | 03/3/2018 |
| These data suggested that Wnt/beta-catenin pathway might be a potential target to treat the LPS-induced inflammation in ALI. | Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice.
Cheng L, Zhao Y, Qi D, Li W, Wang D. | 02/17/2018 |
| Wnt signaling regulates airway epithelial stem cells in adult murine submucosal glands. | Wnt Signaling Regulates Airway Epithelial Stem Cells in Adult Murine Submucosal Glands.
Lynch TJ, Anderson PJ, Xie W, Crooke AK, Liu X, Tyler SR, Luo M, Kusner DM, Zhang Y, Neff T, Burnette DC, Walters KS, Goodheart MJ, Parekh KR, Engelhardt JF., Free PMC Article | 01/27/2018 |
| Pax9-dependent Wnt signaling has a role in palatogenesis and cleft palates | Small-molecule Wnt agonists correct cleft palates in Pax9 mutant mice in utero.
Jia S, Zhou J, Fanelli C, Wee Y, Bonds J, Schneider P, Mues G, D'Souza RN., Free PMC Article | 11/11/2017 |
| Data show that autocrine Wnt secretion is important for the survival, chromosomal stability, differentiation, and tumorigenic potential of embryonic stem cells (ESCs). | Autocrine Wnt regulates the survival and genomic stability of embryonic stem cells.
Augustin I, Dewi DL, Hundshammer J, Erdmann G, Kerr G, Boutros M. | 11/11/2017 |
| Results demonstrated functional differences in the molecular mechanisms downstream of Wnt1 function in the diencephalon, in relation to the spinal cord. Wnt1 signal determines the patterning of the diencephalic dorso-ventral axis | Wnt1 signal determines the patterning of the diencephalic dorso-ventral axis.
Navarro-Garberi M, Bueno C, Martinez S. | 09/30/2017 |