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    Mrtfa myocardin related transcription factor A [ Mus musculus (house mouse) ]

    Gene ID: 223701, updated on 10-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex.

    The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex.
    Khudayberdiev S, Weiss K, Heinze A, Colombaretti D, Trausch N, Linne U, Rust MB.

    06/3/2024
    MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium.

    MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium.
    Singh AK, Rai A, Weber A, Gericke M, Janssen KP, Moser M, Posern G., Free PMC Article

    10/24/2023
    An MRTF-A-ZEB1-IRF9 axis contributes to fibroblast-myofibroblast transition and renal fibrosis.

    An MRTF-A-ZEB1-IRF9 axis contributes to fibroblast-myofibroblast transition and renal fibrosis.
    Zhao Q, Shao T, Zhu Y, Zong G, Zhang J, Tang S, Lin Y, Ma H, Jiang Z, Xu Y, Wu X, Zhang T., Free PMC Article

    06/7/2023
    Myocardin-related transcription factor A, regulated by serum response factor, contributes to diabetic cardiomyopathy in mice.

    Myocardin-related transcription factor A, regulated by serum response factor, contributes to diabetic cardiomyopathy in mice.
    Liu L, Sun K, Luo Y, Wang B, Yang Y, Chen L, Zheng S, Wu T, Xiao P.

    02/28/2023
    MKL1 fuels ROS-induced proliferation of vascular smooth muscle cells by modulating FOXM1 transcription.

    MKL1 fuels ROS-induced proliferation of vascular smooth muscle cells by modulating FOXM1 transcription.
    Wu T, Li N, Zhang Q, Liu R, Zhao H, Fan Z, Zhuo L, Yang Y, Xu Y., Free PMC Article

    01/28/2023
    MRTF-A-mediated protection against amyloid-beta-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models.

    MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models.
    Zhang W, Yang Y, Xiang Z, Cheng J, Yu Z, Wang W, Hu L, Ma F, Deng Y, Jin Z, Hu X., Free PMC Article

    07/2/2022
    Myocardin-related transcription factor A regulates integrin beta 2 transcription to promote macrophage infiltration and cardiac hypertrophy in mice.

    Myocardin-related transcription factor A regulates integrin beta 2 transcription to promote macrophage infiltration and cardiac hypertrophy in mice.
    Liu L, Zhao Q, Kong M, Mao L, Yang Y, Xu Y.

    04/9/2022
    Lamina-associated polypeptide 2alpha is required for intranuclear MRTF-A activity.

    Lamina-associated polypeptide 2α is required for intranuclear MRTF-A activity.
    Sidorenko E, Sokolova M, Pennanen AP, Kyheröinen S, Posern G, Foisner R, Vartiainen MK., Free PMC Article

    03/12/2022
    MRTF-A regulates myoblast commitment to differentiation by targeting PAX7 during muscle regeneration.

    MRTF-A regulates myoblast commitment to differentiation by targeting PAX7 during muscle regeneration.
    Song R, Zhao S, Xu Y, Hu J, Ke S, Li F, Tian G, Zheng X, Li J, Gu L, Xu Y., Free PMC Article

    02/26/2022
    Therapeutic effects of myocardin-related transcription factor A (MRTF-A) knockout on experimental mice with nonalcoholic steatohepatitis induced by high-fat diet.

    Therapeutic effects of myocardin-related transcription factor A (MRTF-A) knockout on experimental mice with nonalcoholic steatohepatitis induced by high-fat diet.
    Zhang L, Li HL, Zhang DD, Cui XC.

    02/5/2022
    Lamin A/C-Dependent Translocation of Megakaryoblastic Leukemia-1 and beta-Catenin in Cyclic Strain-Induced Osteogenesis.

    Lamin A/C-Dependent Translocation of Megakaryoblastic Leukemia-1 and β-Catenin in Cyclic Strain-Induced Osteogenesis.
    Khan AU, Qu R, Yang Y, Fan T, Peng Y, Sun B, Qiu X, Wu S, Wang Z, Zhou Z, Khan MA, Dai J, Ouyang J., Free PMC Article

    01/8/2022
    Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts.

    Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts.
    Kepser LJ, Khudayberdiev S, Hinojosa LS, Macchi C, Ruscica M, Marcello E, Culmsee C, Grosse R, Rust MB., Free PMC Article

    12/18/2021
    Aortic carboxypeptidase-like protein regulates vascular adventitial progenitor and fibroblast differentiation through myocardin related transcription factor A.

    Aortic carboxypeptidase-like protein regulates vascular adventitial progenitor and fibroblast differentiation through myocardin related transcription factor A.
    Wang D, Rabhi N, Yet SF, Farmer SR, Layne MD., Free PMC Article

    12/11/2021
    MRTF-A regulates Ca(2+) release through CACNA1S.

    MRTF-A regulates Ca(2+) release through CACNA1S.
    Liang C, Xu Y, Peng Z, Luo Y, Zhang T.

    12/4/2021
    MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm.

    MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm.
    Gao P, Gao P, Zhao J, Shan S, Luo W, Slivano OJ, Zhang W, Tabuchi A, LeMaire SA, Maegdefessel L, Shen YH, Miano JM, Singer HA, Long X., Free PMC Article

    08/21/2021
    Myocardin-Related Transcription Factor A Mediates LPS-Induced iNOS Transactivation.

    Myocardin-Related Transcription Factor A Mediates LPS-Induced iNOS Transactivation.
    Lin L, Zhang Q, Fan H, Zhao H, Yang Y.

    06/12/2021
    SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-beta/BMP pathway.

    SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-β/BMP pathway.
    Liu R, Xiong X, Nam D, Yechoor V, Ma K., Free PMC Article

    06/12/2021
    Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling.

    Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling.
    Guo Y, Cao Y, Jardin BD, Sethi I, Ma Q, Moghadaszadeh B, Troiano EC, Mazumdar N, Trembley MA, Small EM, Yuan GC, Beggs AH, Pu WT., Free PMC Article

    05/15/2021
    PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR(-/-) Mice by Inhibiting Myocardin-Related Transcription Factor Relays.

    PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR(-/-) Mice by Inhibiting Myocardin-Related Transcription Factor Relays.
    Behrmann A, Zhong D, Li L, Cheng SL, Mead M, Ramachandran B, Sabaeifard P, Goodarzi M, Lemoff A, Kronenberg HM, Towler DA., Free PMC Article

    02/27/2021
    Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts.

    Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts.
    Holstein I, Singh AK, Pohl F, Misiak D, Braun J, Leitner L, Hüttelmaier S, Posern G., Free PMC Article

    10/31/2020
    Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells.

    Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells.
    Yang Y, Li Z, Guo J, Xu Y.

    10/31/2020
    Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A.

    Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A.
    Shao J, Xu H, Wu X, Xu Y.

    10/24/2020
    Profibrotic epithelial phenotype: a central role for MRTF and TAZ.

    Profibrotic epithelial phenotype: a central role for MRTF and TAZ.
    Bialik JF, Ding M, Speight P, Dan Q, Miranda MZ, Di Ciano-Oliveira C, Kofler MM, Rotstein OD, Pedersen SF, Szászi K, Kapus A., Free PMC Article

    10/3/2020
    MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription.

    MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription.
    Li Z, Chen B, Dong W, Kong M, Fan Z, Yu L, Wu D, Lu J, Xu Y., Free PMC Article

    09/5/2020
    A beta2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation.

    A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation.
    Guenther C, Faisal I, Uotila LM, Asens ML, Harjunpää H, Savinko T, Öhman T, Yao S, Moser M, Morris SW, Tojkander S, Fagerholm SC., Free PMC Article

    08/22/2020
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