The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex. | The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex. Khudayberdiev S, Weiss K, Heinze A, Colombaretti D, Trausch N, Linne U, Rust MB. | 06/3/2024 |
MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium. | MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium. Singh AK, Rai A, Weber A, Gericke M, Janssen KP, Moser M, Posern G., Free PMC Article | 10/24/2023 |
An MRTF-A-ZEB1-IRF9 axis contributes to fibroblast-myofibroblast transition and renal fibrosis. | An MRTF-A-ZEB1-IRF9 axis contributes to fibroblast-myofibroblast transition and renal fibrosis. Zhao Q, Shao T, Zhu Y, Zong G, Zhang J, Tang S, Lin Y, Ma H, Jiang Z, Xu Y, Wu X, Zhang T., Free PMC Article | 06/7/2023 |
Myocardin-related transcription factor A, regulated by serum response factor, contributes to diabetic cardiomyopathy in mice. | Myocardin-related transcription factor A, regulated by serum response factor, contributes to diabetic cardiomyopathy in mice. Liu L, Sun K, Luo Y, Wang B, Yang Y, Chen L, Zheng S, Wu T, Xiao P. | 02/28/2023 |
MKL1 fuels ROS-induced proliferation of vascular smooth muscle cells by modulating FOXM1 transcription. | MKL1 fuels ROS-induced proliferation of vascular smooth muscle cells by modulating FOXM1 transcription. Wu T, Li N, Zhang Q, Liu R, Zhao H, Fan Z, Zhuo L, Yang Y, Xu Y., Free PMC Article | 01/28/2023 |
MRTF-A-mediated protection against amyloid-beta-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models. | MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models. Zhang W, Yang Y, Xiang Z, Cheng J, Yu Z, Wang W, Hu L, Ma F, Deng Y, Jin Z, Hu X., Free PMC Article | 07/2/2022 |
Myocardin-related transcription factor A regulates integrin beta 2 transcription to promote macrophage infiltration and cardiac hypertrophy in mice. | Myocardin-related transcription factor A regulates integrin beta 2 transcription to promote macrophage infiltration and cardiac hypertrophy in mice. Liu L, Zhao Q, Kong M, Mao L, Yang Y, Xu Y. | 04/9/2022 |
Lamina-associated polypeptide 2alpha is required for intranuclear MRTF-A activity. | Lamina-associated polypeptide 2α is required for intranuclear MRTF-A activity. Sidorenko E, Sokolova M, Pennanen AP, Kyheröinen S, Posern G, Foisner R, Vartiainen MK., Free PMC Article | 03/12/2022 |
MRTF-A regulates myoblast commitment to differentiation by targeting PAX7 during muscle regeneration. | MRTF-A regulates myoblast commitment to differentiation by targeting PAX7 during muscle regeneration. Song R, Zhao S, Xu Y, Hu J, Ke S, Li F, Tian G, Zheng X, Li J, Gu L, Xu Y., Free PMC Article | 02/26/2022 |
Therapeutic effects of myocardin-related transcription factor A (MRTF-A) knockout on experimental mice with nonalcoholic steatohepatitis induced by high-fat diet. | Therapeutic effects of myocardin-related transcription factor A (MRTF-A) knockout on experimental mice with nonalcoholic steatohepatitis induced by high-fat diet. Zhang L, Li HL, Zhang DD, Cui XC. | 02/5/2022 |
Lamin A/C-Dependent Translocation of Megakaryoblastic Leukemia-1 and beta-Catenin in Cyclic Strain-Induced Osteogenesis. | Lamin A/C-Dependent Translocation of Megakaryoblastic Leukemia-1 and β-Catenin in Cyclic Strain-Induced Osteogenesis. Khan AU, Qu R, Yang Y, Fan T, Peng Y, Sun B, Qiu X, Wu S, Wang Z, Zhou Z, Khan MA, Dai J, Ouyang J., Free PMC Article | 01/8/2022 |
Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts. | Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts. Kepser LJ, Khudayberdiev S, Hinojosa LS, Macchi C, Ruscica M, Marcello E, Culmsee C, Grosse R, Rust MB., Free PMC Article | 12/18/2021 |
Aortic carboxypeptidase-like protein regulates vascular adventitial progenitor and fibroblast differentiation through myocardin related transcription factor A. | Aortic carboxypeptidase-like protein regulates vascular adventitial progenitor and fibroblast differentiation through myocardin related transcription factor A. Wang D, Rabhi N, Yet SF, Farmer SR, Layne MD., Free PMC Article | 12/11/2021 |
MRTF-A regulates Ca(2+) release through CACNA1S. | MRTF-A regulates Ca(2+) release through CACNA1S. Liang C, Xu Y, Peng Z, Luo Y, Zhang T. | 12/4/2021 |
MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm. | MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm. Gao P, Gao P, Zhao J, Shan S, Luo W, Slivano OJ, Zhang W, Tabuchi A, LeMaire SA, Maegdefessel L, Shen YH, Miano JM, Singer HA, Long X., Free PMC Article | 08/21/2021 |
Myocardin-Related Transcription Factor A Mediates LPS-Induced iNOS Transactivation. | Myocardin-Related Transcription Factor A Mediates LPS-Induced iNOS Transactivation. Lin L, Zhang Q, Fan H, Zhao H, Yang Y. | 06/12/2021 |
SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-beta/BMP pathway. | SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-β/BMP pathway. Liu R, Xiong X, Nam D, Yechoor V, Ma K., Free PMC Article | 06/12/2021 |
Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling. | Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling. Guo Y, Cao Y, Jardin BD, Sethi I, Ma Q, Moghadaszadeh B, Troiano EC, Mazumdar N, Trembley MA, Small EM, Yuan GC, Beggs AH, Pu WT., Free PMC Article | 05/15/2021 |
PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR(-/-) Mice by Inhibiting Myocardin-Related Transcription Factor Relays. | PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR(-/-) Mice by Inhibiting Myocardin-Related Transcription Factor Relays. Behrmann A, Zhong D, Li L, Cheng SL, Mead M, Ramachandran B, Sabaeifard P, Goodarzi M, Lemoff A, Kronenberg HM, Towler DA., Free PMC Article | 02/27/2021 |
Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts. | Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts. Holstein I, Singh AK, Pohl F, Misiak D, Braun J, Leitner L, Hüttelmaier S, Posern G., Free PMC Article | 10/31/2020 |
Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells. | Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells. Yang Y, Li Z, Guo J, Xu Y. | 10/31/2020 |
Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A. | Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A. Shao J, Xu H, Wu X, Xu Y. | 10/24/2020 |
Profibrotic epithelial phenotype: a central role for MRTF and TAZ. | Profibrotic epithelial phenotype: a central role for MRTF and TAZ. Bialik JF, Ding M, Speight P, Dan Q, Miranda MZ, Di Ciano-Oliveira C, Kofler MM, Rotstein OD, Pedersen SF, Szászi K, Kapus A., Free PMC Article | 10/3/2020 |
MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription. | MKL1 promotes endothelial-to-mesenchymal transition and liver fibrosis by activating TWIST1 transcription. Li Z, Chen B, Dong W, Kong M, Fan Z, Yu L, Wu D, Lu J, Xu Y., Free PMC Article | 09/5/2020 |
A beta2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation. | A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation. Guenther C, Faisal I, Uotila LM, Asens ML, Harjunpää H, Savinko T, Öhman T, Yao S, Moser M, Morris SW, Tojkander S, Fagerholm SC., Free PMC Article | 08/22/2020 |