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    Vim vimentin [ Mus musculus (house mouse) ]

    Gene ID: 22352, updated on 16-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Vimentin supports cell polarization by enhancing centrosome function and microtubule acetylation.

    Vimentin supports cell polarization by enhancing centrosome function and microtubule acetylation.
    Saldanha R, Ho Thanh MT, Krishnan N, Hehnly H, Patteson A., Free PMC Article

    07/9/2024
    Vimentin takes a hike - Emerging roles of extracellular vimentin in cancer and wound healing.

    Vimentin takes a hike - Emerging roles of extracellular vimentin in cancer and wound healing.
    Parvanian S, Coelho-Rato LS, Patteson AE, Eriksson JE., Free PMC Article

    12/15/2023
    Co-expression of galectin-3 and vimentin in triple negative breast cancer cells promotes tumor progression, metastasis and survival.

    Co-expression of galectin-3 and vimentin in triple negative breast cancer cells promotes tumor progression, metastasis and survival.
    Jeethy Ram T, Lekshmi A, Darvin P, Rajappan P, Jagathnath Krishna KM, Anoop TM, Augustine P, Mathew AP, Cherian K, Bhargavan RV, Somanathan T, Radhakrishna Pillai M, Santhosh Kumar TR, Sujathan K.

    08/19/2023
    Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer.

    Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer.
    Berr AL, Wiese K, Dos Santos G, Koch CM, Anekalla KR, Kidd M, Davis JM, Cheng Y, Hu YS, Ridge KM., Free PMC Article

    06/21/2023
    Roles of vimentin in health and disease.

    Roles of vimentin in health and disease.
    Ridge KM, Eriksson JE, Pekny M, Goldman RD., Free PMC Article

    05/14/2022
    Vimentin Inhibits Dengue Virus Type 2 Invasion of the Blood-Brain Barrier.

    Vimentin Inhibits Dengue Virus Type 2 Invasion of the Blood-Brain Barrier.
    Yu J, Li X, Zhou D, Liu X, He X, Huang SH, Wu Q, Zhu L, Yu L, Yao J, Zhang B, Zhao W., Free PMC Article

    04/30/2022
    Vimentin Intermediate Filaments Mediate Cell Morphology on Viscoelastic Substrates.

    Vimentin Intermediate Filaments Mediate Cell Morphology on Viscoelastic Substrates.
    Swoger M, Gupta S, Charrier EE, Bates M, Hehnly H, Patteson AE., Free PMC Article

    04/16/2022
    RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Muller glial cell hypertrophy in progressive retinal degeneration.

    RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration.
    Hippert C, Graca AB, Basche M, Kalargyrou AA, Georgiadis A, Ribeiro J, Matsuyama A, Aghaizu N, Bainbridge JW, Smith AJ, Ali RR, Pearson RA.

    03/19/2022
    Rapid tumor recurrence in a novel murine GBM surgical model is associated with Akt/PD-L1/vimentin signaling.

    Rapid tumor recurrence in a novel murine GBM surgical model is associated with Akt/PD-L1/vimentin signaling.
    Liu F, Xu XH, Li CY, Zhang TT, Yin SL, Liu GQ, Hu F, Yu SB, Chen XQ.

    11/27/2021
    Vimentin Association with Nuclear Grooves in Normal MEF 3T3 Cells.

    Vimentin Association with Nuclear Grooves in Normal MEF 3T3 Cells.
    Feliksiak K, Witko T, Solarz D, Guzik M, Rajfur Z., Free PMC Article

    05/15/2021
    Vimentin protects differentiating stem cells from stress.

    Vimentin protects differentiating stem cells from stress.
    Pattabiraman S, Azad GK, Amen T, Brielle S, Park JE, Sze SK, Meshorer E, Kaganovich D., Free PMC Article

    05/8/2021
    Ablation of miR-144 increases vimentin expression and atherosclerotic plaque formation.

    Ablation of miR-144 increases vimentin expression and atherosclerotic plaque formation.
    He Q, Wang F, Honda T, Greis KD, Redington AN., Free PMC Article

    11/28/2020
    Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress.

    Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress.
    van Engeland NCA, Suarez Rodriguez F, Rivero-Müller A, Ristori T, Duran CL, Stassen OMJA, Antfolk D, Driessen RCH, Ruohonen S, Ruohonen ST, Nuutinen S, Savontaus E, Loerakker S, Bayless KJ, Sjöqvist M, Bouten CVC, Eriksson JE, Sahlgren CM., Free PMC Article

    10/24/2020
    Loss of Vimentin Enhances Cell Motility through Small Confining Spaces.

    Loss of Vimentin Enhances Cell Motility through Small Confining Spaces.
    Patteson AE, Pogoda K, Byfield FJ, Mandal K, Ostrowska-Podhorodecka Z, Charrier EE, Galie PA, Deptuła P, Bucki R, McCulloch CA, Janmey PA., Free PMC Article

    10/3/2020
    Induction of Vimentin-mediated signaling (by CPT) delayed apoptosis progression in cells conferring survival responses by modulating the promoter activity of NFkappaB.

    Vimentin activation in early apoptotic cancer cells errands survival pathways during DNA damage inducer CPT treatment in colon carcinoma model.
    Chakraborty S, Kumar A, Faheem MM, Katoch A, Kumar A, Jamwal VL, Nayak D, Golani A, Rasool RU, Ahmad SM, Jose J, Kumar R, Gandhi SG, Dinesh Kumar L, Goswami A., Free PMC Article

    07/18/2020
    Inhibition of vimentin intermediate filaments decreases the invasiveness of idiopathic pulmonary fibrosis fibroblasts, increases autophagic clearance of collagen type I, and confers protection against fibrosis in a murine model of experimental lung injury. This study provides insights into the functional role of vimentin, which regulates autophagy and restricts the invasiveness of lung fibroblasts.

    Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury.
    Surolia R, Li FJ, Wang Z, Li H, Dsouza K, Thomas V, Mirov S, Pérez-Sala D, Athar M, Thannickal VJ, Antony VB., Free PMC Article

    07/4/2020
    vimentin intermediate filaments provide mechanical support to protect the nucleus and genome during migration

    Vimentin protects cells against nuclear rupture and DNA damage during migration.
    Patteson AE, Vahabikashi A, Pogoda K, Adam SA, Mandal K, Kittisopikul M, Sivagurunathan S, Goldman A, Goldman RD, Janmey PA., Free PMC Article

    06/6/2020
    The siRNA-mediated repression of vimentin in FOXK1-overexpressing cells reversed the epithelial-mesenchymal transition -like phenotype and reduced Gastric Cancer cell migration and invasion in vitro and in vivo.

    Coexpression of FOXK1 and vimentin promotes EMT, migration, and invasion in gastric cancer cells.
    Zhang H, Wu X, Xiao Y, Wu L, Peng Y, Tang W, Liu G, Sun Y, Wang J, Zhu H, Liu M, Zhang W, Dai W, Jiang P, Li A, Li G, Xiang L, Liu S, Wang J.

    05/30/2020
    Mutation of mitotic phosphorylation sites in vimentin triggers formation of vimentin accumulations and cytokinetic failure in immature astrocytes.

    Vimentin Phosphorylation Is Required for Normal Cell Division of Immature Astrocytes.
    de Pablo Y, Marasek P, Pozo-Rodrigálvarez A, Wilhelmsson U, Inagaki M, Pekna M, Pekny M., Free PMC Article

    05/16/2020
    assessed the locomotor and exploratory behavior of GFAP-/-Vim-/- mice, their learning, memory and memory extinction, by using the open field, object recognition and Morris water maze tests, trace fear conditioning, and by recording reversal learning in IntelliCages

    The role of GFAP and vimentin in learning and memory.
    Wilhelmsson U, Pozo-Rodrigalvarez A, Kalm M, de Pablo Y, Widestrand Å, Pekna M, Pekny M.

    02/22/2020
    conclude that vimentin is required for the normal accumulation of body fat

    Vimentin is required for normal accumulation of body fat.
    Wilhelmsson U, Stillemark-Billton P, Borén J, Pekny M.

    02/22/2020
    vimentin has a key role in regulating inflammation in macrophages during atherogenesis

    Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice.
    Håversen L, Sundelin JP, Mardinoglu A, Rutberg M, Ståhlman M, Wilhelmsson U, Hultén LM, Pekny M, Fogelstrand P, Bentzon JF, Levin M, Borén J., Free PMC Article

    12/14/2019
    The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis.

    The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis.
    Deng L, Spencer BL, Holmes JA, Mu R, Rego S, Weston TA, Hu Y, Sanches GF, Yoon S, Park N, Nagao PE, Jenkinson HF, Thornton JA, Seo KS, Nobbs AH, Doran KS., Free PMC Article

    12/7/2019
    vimentin resists the stress fiber contractility, as hypothesized, thus indicating the importance of vimentin in regulating cellular stress generation by adherent cells

    The Mechanical Contribution of Vimentin to Cellular Stress Generation.
    van Loosdregt IAEW, Weissenberger G, van Maris MPFHL, Oomens CWJ, Loerakker S, Stassen OMJA, Bouten CVC.

    10/5/2019
    This study detected a seemingly proliferative first response from ischemia-activated vimentin-induced cardiac endogenous mesenchymal stem cells with spatial enrichment in the early infarction border zone after acute myocardial infarction.

    Vimentin-Induced Cardiac Mesenchymal Stem Cells Proliferate in the Acute Ischemic Myocardium.
    Klopsch C, Gaebel R, Lemcke H, Beyer M, Vasudevan P, Fang HY, Quante M, Vollmar B, Skorska A, David R, Steinhoff G.

    09/21/2019
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