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    RBM24 RNA binding motif protein 24 [ Homo sapiens (human) ]

    Gene ID: 221662, updated on 19-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    YAP1-induced RBM24 promotes the tumorigenesis of triple-negative breast cancer through the beta-catenin pathway.

    YAP1-induced RBM24 promotes the tumorigenesis of triple-negative breast cancer through the β-catenin pathway.
    Chen X, Lin X, Xia X, Xiang X.

    09/5/2024
    Rbm24 modulates neuronal RNA splicing to restrict cognitive dysfunction.

    Rbm24 modulates neuronal RNA splicing to restrict cognitive dysfunction.
    Yao D, Wang X, Liu J, Xu XQ.

    08/21/2024
    MiR-20a-5p targets RBM24 and alleviates hypertensive intracerebral hemorrhage.

    MiR-20a-5p targets RBM24 and alleviates hypertensive intracerebral hemorrhage.
    Xu L, Mo C, Lu M, Wang P, Liu Y.

    01/4/2024
    RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5'-untranslated region.

    RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5'-untranslated region.
    Yao Y, Sun H, Chen Y, Tian L, Huang D, Liu C, Zhou Y, Wang Y, Wen Z, Yang B, Chen X, Pei R., Free PMC Article

    01/21/2023
    RBM24 controls cardiac QT interval through CaMKIIdelta splicing.

    RBM24 controls cardiac QT interval through CaMKIIδ splicing.
    Liu J, Wang K, Liu X, Pan L, Zhou W, Huang J, Liu H, Su Z, Xu XQ.

    12/10/2022
    RBM24 exacerbates bladder cancer progression by forming a Runx1t1/TCF4/miR-625-5p feedback loop.

    RBM24 exacerbates bladder cancer progression by forming a Runx1t1/TCF4/miR-625-5p feedback loop.
    Yin YW, Liu KL, Lu BS, Li W, Niu YL, Zhao CM, Yang Z, Guo PY, Qi JC., Free PMC Article

    03/26/2022
    Alternative Splicing Mediated by RNA-Binding Protein RBM24 Facilitates Cardiac Myofibrillogenesis in a Differentiation Stage-Specific Manner.

    Alternative Splicing Mediated by RNA-Binding Protein RBM24 Facilitates Cardiac Myofibrillogenesis in a Differentiation Stage-Specific Manner.
    Lu SH, Lee KZ, Hsu PW, Su LY, Yeh YC, Pan CY, Tsai SY.

    02/26/2022
    RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA.

    RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA.
    Xia RM, Liu T, Li WG, Xu XQ., Free PMC Article

    02/26/2022
    TPRG1-AS1 induces RBM24 expression and inhibits liver cancer progression by sponging miR-4691-5p and miR-3659.

    TPRG1-AS1 induces RBM24 expression and inhibits liver cancer progression by sponging miR-4691-5p and miR-3659.
    Choi JH, Kwon SM, Moon SU, Yoon S, Shah M, Lee BG, Yang J, Park YN, Wang HJ, Woo HG.

    11/6/2021
    TRIM56 suppresses the malignant development of hepatocellular carcinoma via targeting RBM24 and inactivating the Wnt signaling.

    TRIM56 suppresses the malignant development of hepatocellular carcinoma via targeting RBM24 and inactivating the Wnt signaling.
    Yang Y, Mao FF, Guo L, Guo WX.

    07/3/2021
    Circular RNA SMARCA5 suppressed non-small cell lung cancer progression by regulating miR-670-5p/RBM24 axis.

    Circular RNA SMARCA5 suppressed non-small cell lung cancer progression by regulating miR-670-5p/RBM24 axis.
    Zhang D, Ma Y, Ma Z, Liu S, Sun L, Li J, Zhao F, Li Y, Zhang J, Li S, Jiang J.

    05/1/2021
    The host factor RBM24 is involved in pregenomic RNA (pgRNA) packaging.

    RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element.
    Yao Y, Yang B, Chen Y, Wang H, Hu X, Zhou Y, Gao X, Lu M, Niu J, Wen Z, Wu C, Chen X., Free PMC Article

    11/23/2019
    The RBM24 is a novel host factor involved in HCV replication and may function at the switch from translation to replication.

    RNA binding protein 24 regulates the translation and replication of hepatitis C virus.
    Cao H, Zhao K, Yao Y, Guo J, Gao X, Yang Q, Guo M, Zhu W, Wang Y, Wu C, Chen J, Zhou Y, Hu X, Lu M, Chen X, Pei R., Free PMC Article

    07/20/2019
    Data suggests that RBM24 binds to coding region of CHRM2 to regulate mRNA stability in cardiomyocytes; RBM24appears to drive changes in alternative splicing and in production of alternative transcript isoforms. (RBM24 = RNA binding motif protein-24; CHRM2 = cholinergic receptor muscarinic 2)

    Global profiling of Rbm24 bound RNAs uncovers a multi-tasking RNA binding protein.
    Lin Y, Tan KT, Liu J, Kong X, Huang Z, Xu XQ.

    10/20/2018
    RBM24 interacted with the 5' TR of HBV pregenomic RNA to block 80S ribosome assembly on HBV pgRNA and thus inhibited core protein translation, whereas the interaction between RBM24 and the 3' TR enhanced the stability of HBV RNA.

    RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence.
    Yao Y, Yang B, Cao H, Zhao K, Yuan Y, Chen Y, Zhang Z, Wang Y, Pei R, Chen J, Hu X, Zhou Y, Lu M, Wu C, Chen X., Free PMC Article

    09/15/2018
    embryonic stem cell switching into the differentiation state can be initiated by a tissue-specific splicing regulator, Rbm24.

    Rbm24 Regulates Alternative Splicing Switch in Embryonic Stem Cell Cardiac Lineage Differentiation.
    Zhang T, Lin Y, Liu J, Zhang ZG, Fu W, Guo LY, Pan L, Kong X, Zhang MK, Lu YH, Huang ZR, Xie Q, Li WH, Xu XQ.

    12/9/2017
    Our results show that tissue-specific expression of RBM24 can explain the neuron-specific aberrant splicing of IKBKAP exon 20 in familial dysautonomia, and that ectopic expression of RBM24 in neuronal tissue could be a novel therapeutic target of the disease.

    RBM24 promotes U1 snRNP recognition of the mutated 5' splice site in the IKBKAP gene of familial dysautonomia.
    Ohe K, Yoshida M, Nakano-Kobayashi A, Hosokawa M, Sako Y, Sakuma M, Okuno Y, Usui T, Ninomiya K, Nojima T, Kataoka N, Hagiwara M., Free PMC Article

    10/14/2017
    RBM24 acts at least in part through upregulating the expression of miR-25, which in turn targets MALAT1 for degradation.

    RBM24 suppresses cancer progression by upregulating miR-25 to target MALAT1 in nasopharyngeal carcinoma.
    Hua WF, Zhong Q, Xia TL, Chen Q, Zhang MY, Zhou AJ, Tu ZW, Qu C, Li MZ, Xia YF, Wang HY, Xie D, Claret FX, Song EW, Zeng MS., Free PMC Article

    10/7/2017
    Authors have identified a new function of microRNA-222 leading to alteration of myogenic differentiation at the level of alternative splicing, and provided evidence that this effect is mediated by Rbm24 protein.

    MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells.
    Cardinali B, Cappella M, Provenzano C, Garcia-Manteiga JM, Lazarevic D, Cittaro D, Martelli F, Falcone G., Free PMC Article

    12/17/2016
    Study suggests that p63 is regulated by RBM24 via mRNA stability, which gives an insight into understanding how posttranscriptional regulatory mechanisms contribute to p63 expression.

    RNA-binding protein RBM24 regulates p63 expression via mRNA stability.
    Xu E, Zhang J, Zhang M, Jiang Y, Cho SJ, Chen X., Free PMC Article

    01/17/2015
    Rbm24 is a novel player in the p53 pathway, which may be explored to restore proper cell cycle control in p53-deficient tumors via p21.

    Rbm24, an RNA-binding protein and a target of p53, regulates p21 expression via mRNA stability.
    Jiang Y, Zhang M, Qian Y, Xu E, Zhang J, Chen X., Free PMC Article

    04/12/2014
    it was found that this protein Rbm24 regulates myogenic differentiation via the p21 signal pathway.

    RNA-binding proteins Rbm38 and Rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways.
    Miyamoto S, Hidaka K, Jin D, Morisaki T.

    03/15/2010
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