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    FCGR2A Fc gamma receptor IIa [ Homo sapiens (human) ]

    Gene ID: 2212, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD32 captures committed haemogenic endothelial cells during human embryonic development.

    CD32 captures committed haemogenic endothelial cells during human embryonic development.
    Scarfò R, Randolph LN, Abou Alezz M, El Khoury M, Gersch A, Li ZY, Luff SA, Tavosanis A, Ferrari Ramondo G, Valsoni S, Cascione S, Didelon E, Passerini L, Amodio G, Brandas C, Villa A, Gregori S, Merelli I, Freund JN, Sturgeon CM, Tavian M, Ditadi A., Free PMC Article

    08/13/2024
    Regulatory mechanism of FCGR2A in macrophage polarization and its effects on intervertebral disc degeneration.

    Regulatory mechanism of FCGR2A in macrophage polarization and its effects on intervertebral disc degeneration.
    Luo J, Jin G, Cui S, Wang H, Liu Q.

    04/12/2024
    Genetic variation of FcgammaRIIa induces higher uptake of Leishmania infantum and modulates cytokine production by adherent mononuclear cells in vitro.

    Genetic variation of FcγRIIa induces higher uptake of Leishmania infantum and modulates cytokine production by adherent mononuclear cells in vitro.
    Catarino JDS, de Oliveira RF, Silva MV, Sales-Campos H, de Vito FB, da Silva DAA, Naves LL, Oliveira CJF, Rodrigues DBR, Rodrigues V Jr., Free PMC Article

    03/13/2024
    New candidate SNPs for genetic association with Alzheimer's disease: a linkage disequilibrium analysis for the FCGRIIB and PILRA genes.

    New candidate SNPs for genetic association with Alzheimer's disease: a linkage disequilibrium analysis for the FCGRIIB and PILRA genes.
    Levi-Monsalve A, Flores SV, Manriquez G, Roco-Videla Á.

    02/29/2024
    Platelet FcgammaRIIa expression in patients with stable coronary artery disease.

    Platelet FcγRIIa expression in patients with stable coronary artery disease.
    Adamian R, McCleary P, Sharma T, Schneider DJ.

    02/27/2024
    Relationship Between Human FCgammaRIIA rs1801274 G Allele and Risk of Death Among Different SARS-CoV-2 Variants.

    Relationship Between Human FCγRIIA rs1801274 G Allele and Risk of Death Among Different SARS-CoV-2 Variants.
    Moghaddam N, Goodarzi MT, Moghaddam S, Sakhaee F, Ahmadi I, Anvari E, Fateh A.

    01/3/2024
    Association between functional FCGR3A F158V and FCGR2A R131H polymorphisms and responsiveness to rituximab in patients with autoimmune diseases: a meta-analysis.

    Association between functional FCGR3A F158V and FCGR2A R131H polymorphisms and responsiveness to rituximab in patients with autoimmune diseases: a meta-analysis.
    Lee YH, Song GG.

    11/22/2023
    Association between the functional FCGR3A F158V and FCGR2A R131H polymorphisms and responsiveness to biologics in rheumatoid arthritis patients: A meta-analysis.

    Association between the functional FCGR3A F158V and FCGR2A R131H polymorphisms and responsiveness to biologics in rheumatoid arthritis patients: A meta-analysis.
    Lee YH, Song GG.

    07/7/2023
    Comparative Analysis of FCGR Gene Polymorphism in Pulmonary Sarcoidosis and Tuberculosis.

    Comparative Analysis of FCGR Gene Polymorphism in Pulmonary Sarcoidosis and Tuberculosis.
    Typiak M, Rękawiecki B, Rębała K, Dubaniewicz A., Free PMC Article

    05/24/2023
    Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease.

    Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease.
    Dahlqvist J, Fulco CP, Ray JP, Liechti T, de Boer CG, Lieb DJ, Eisenhaure TM, Engreitz JM, Roederer M, Hacohen N., Free PMC Article

    07/2/2022
    Cytoskeleton Dependent Mobility Dynamics of FcgammaRIIA Facilitates Platelet Haptotaxis and Capture of Opsonized Bacteria.

    Cytoskeleton Dependent Mobility Dynamics of FcγRIIA Facilitates Platelet Haptotaxis and Capture of Opsonized Bacteria.
    Palankar R, Sachs L, Wesche J, Greinacher A., Free PMC Article

    06/11/2022
    Genetic polymorphisms of FCGR2A, ORAI1 and CD40 are associated with risk of lung cancer.

    Genetic polymorphisms of FCGR2A, ORAI1 and CD40 are associated with risk of lung cancer.
    He J, Yu L, Qiao Z, Yu B, Liu Y, Ren H.

    04/30/2022
    The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients.

    The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients.
    López-Martínez R, Albaiceta GM, Amado-Rodríguez L, Cuesta-Llavona E, Gómez J, García-Clemente M, Vázquez-Coto D, Alvarez V, Coto E., Free PMC Article

    03/19/2022
    Fc fragment of immunoglobulin G receptor IIa (FCGR2A) as a new potential prognostic biomarker of esophageal squamous cell carcinoma.

    Fc fragment of immunoglobulin G receptor IIa (FCGR2A) as a new potential prognostic biomarker of esophageal squamous cell carcinoma.
    Lu S, Li N, Peng Z, Lu Z, Tu X, Zhang W, Kang Y., Free PMC Article

    03/5/2022
    Association of Variants in FCGR2A, PTPN2, and GM-CSF with Cerebral Cavernous Malformation: Potential Biomarkers for a Symptomatic Disease.

    Association of Variants in FCGR2A, PTPN2, and GM-CSF with Cerebral Cavernous Malformation: Potential Biomarkers for a Symptomatic Disease.
    da Fontoura Galváo G, Fontes-Dantas FL, da Silva EV, Alves-Leon SV, de Souza JM.

    02/26/2022
    Significant differences in FcgammaRIIa, FcgammaRIIIa and FcgammaRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children.

    Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children.
    Nasr A, Aljada A, Hamid O, Elsheikh HA, Masuadi E, Al-Bawab A, Alenazi TH, Abushouk A, Salah AM., Free PMC Article

    01/15/2022
    Functional Fc Gamma Receptor Gene Polymorphisms and Long-Term Kidney Allograft Survival.

    Functional Fc Gamma Receptor Gene Polymorphisms and Long-Term Kidney Allograft Survival.
    Wahrmann M, Döhler B, Arnold ML, Scherer S, Mayer KA, Haindl S, Haslacher H, Böhmig GA, Süsal C., Free PMC Article

    12/25/2021
    CD137 ligand interacts with CD32a to trigger reverse CD137 ligand signaling.

    CD137 ligand interacts with CD32a to trigger reverse CD137 ligand signaling.
    Zeng Q, Soe YM, Lim Y, Sobota RM, Schwarz H., Free PMC Article

    10/2/2021
    FCGR2A Could Function as a Prognostic Marker and Correlate with Immune Infiltration in Head and Neck Squamous Cell Carcinoma.

    FCGR2A Could Function as a Prognostic Marker and Correlate with Immune Infiltration in Head and Neck Squamous Cell Carcinoma.
    Dai Y, Chen W, Huang J, Cui T., Free PMC Article

    09/25/2021
    Association of TNF-alpha rs1800629, CASP3 rs72689236 and FCGR2A rs1801274 Polymorphisms with Susceptibility to Kawasaki Disease: A Comprehensive Meta-Analysis.

    Association of TNF-α rs1800629, CASP3 rs72689236 and FCGR2A rs1801274 Polymorphisms with Susceptibility to Kawasaki Disease: A Comprehensive Meta-Analysis.
    Ferdosian F, Dastgheib SA, Hosseini-Jangjou SH, Nafei Z, Lookzadeh MH, Noorishadkam M, Mirjalili SR, Neamatzadeh H.

    09/4/2021
    Fcgamma Receptor IIa (FCGR2A) Polymorphism Is Associated With Severe Respiratory Syncytial Virus Disease in Argentinian Infants.

    Fcγ Receptor IIa (FCGR2A) Polymorphism Is Associated With Severe Respiratory Syncytial Virus Disease in Argentinian Infants.
    Holgado MP, Raiden S, Sananez I, Seery V, De Lillo L, Maldonado LL, Kamenetzky L, Geffner J, Arruvito L., Free PMC Article

    07/24/2021
    Susceptibility to Plasmodium falciparum Malaria: Influence of Combined Polymorphisms of IgG3 Gm Allotypes and Fc Gamma Receptors IIA, IIIA, and IIIB.

    Susceptibility to Plasmodium falciparum Malaria: Influence of Combined Polymorphisms of IgG3 Gm Allotypes and Fc Gamma Receptors IIA, IIIA, and IIIB.
    Fall AKDJ, Dechavanne C, Sabbagh A, Guitard E, Milet J, Garcia A, Dugoujon JM, Courtin D, Migot-Nabias F., Free PMC Article

    06/26/2021
    A FcRIIa polymorphism has a HLA-B57 and HLA-B27 independent effect on HIV disease outcome.

    A FcɣRIIa polymorphism has a HLA-B57 and HLA-B27 independent effect on HIV disease outcome.
    Carapito R, Mayr L, Molitor A, Verniquet M, Schmidt S, Tahar O, Partisani M, Rey D, Lambotte O, Bahram S, Moog C.

    05/29/2021
    Biolayer Interferometry-based FcgammaRIIa binding assay for a therapeutic antibody with strong effector function.

    Biolayer Interferometry-based FcγRIIa binding assay for a therapeutic antibody with strong effector function.
    Bajardi-Taccioli A, Co C, Bond C, Masci A, Brantley T, Xu C, Bergelson S, Feschenko M.

    05/29/2021
    Functional Interactions of Common Allotypes of Rhesus Macaque FcgammaR2A and FcgammaR3A with Human and Macaque IgG Subclasses.

    Functional Interactions of Common Allotypes of Rhesus Macaque FcγR2A and FcγR3A with Human and Macaque IgG Subclasses.
    Grunst MW, Grandea AG 3rd, Janaka SK, Hammad I, Grimes P, Karl JA, Wiseman R, O'Connor DH, Evans DT., Free PMC Article

    04/17/2021
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