U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    FCER2 Fc epsilon receptor II [ Homo sapiens (human) ]

    Gene ID: 2208, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Role of CD23 Activated ERK Signaling Pathway in the Pathogenesis of Eosinophilic Chronic Sinusitis with Nasal Polyps.

    Role of CD23 Activated ERK Signaling Pathway in the Pathogenesis of Eosinophilic Chronic Sinusitis with Nasal Polyps.
    Xu M, Chen Z, Jiang Q, Gong Y, Tang H.

    12/5/2023
    IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases.

    IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases.
    Aranda CJ, Gonzalez-Kozlova E, Saunders SP, Fernandes-Braga W, Ota M, Narayanan S, He JS, Del Duca E, Swaroop B, Gnjatic S, Shattner G, Reibman J, Soter NA, Guttman-Yassky E, Curotto de Lafaille MA., Free PMC Article

    03/6/2023
    An FCER2 polymorphism is associated with increased oral leukotriene receptor antagonists and allergic rhinitis prescribing.

    An FCER2 polymorphism is associated with increased oral leukotriene receptor antagonists and allergic rhinitis prescribing.
    Soares P, Fidler K, Felton J, Jones CJ, Tavendale R, Hövels A, Bremner S, Palmer CNA, Mukhopadhyay S.

    05/21/2022
    Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23.

    Reviving lost binding sites: Exploring calcium-binding site transitions between human and murine CD23.
    Ilkow VF, Davies AM, Dhaliwal B, Beavil AJ, Sutton BJ, McDonnell JM., Free PMC Article

    04/9/2022
    Bidirectional Transport of IgE by CD23 in the Inner Ear of Patients with Meniere's Disease.

    Bidirectional Transport of IgE by CD23 in the Inner Ear of Patients with Meniere's Disease.
    Zhang N, Lyu Y, Guo J, Liu J, Song Y, Fan Z, Li X, Li N, Zhang D, Wang H., Free PMC Article

    02/26/2022
    Plasmablasts derive from CD23- activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction.

    Plasmablasts derive from CD23- activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction.
    Pignarre A, Chatonnet F, Caron G, Haas M, Desmots F, Fest T.

    07/24/2021
    Correlations between exhaled nitric oxide, rs28364072 polymorphism of FCER2 gene, asthma control, and inhaled corticosteroid responsiveness in children with asthma.

    Correlations between exhaled nitric oxide, rs28364072 polymorphism of FCER2 gene, asthma control, and inhaled corticosteroid responsiveness in children with asthma.
    Duong-Quy S, Le-Thi-Minh H, Nguyen-Thi-Bich H, Pham-Thu H, Thom VT, Pham-Thi-Hong N, Duong-Thi-Ly H, Nguyen-Huy B, Ngo-Minh X, Nguyen-Thi-Dieu T, Craig TJ.

    06/19/2021
    CD23 mediated the induction of pro-inflammatory cytokines Interleukin-1 beta and tumor necrosis factors-alpha in Aspergillus fumigatus keratitis.

    CD23 mediated the induction of pro-inflammatory cytokines Interleukin-1 beta and tumor necrosis factors-alpha in Aspergillus fumigatus keratitis.
    Yan HJ, Jiang N, Hu LT, Xu Q, Peng XD, Yang H, Zhao WY, Lyu LY, Wang LM, Che CY., Free PMC Article

    06/12/2021
    Human DC-SIGN and CD23 do not interact with human IgG.

    Human DC-SIGN and CD23 do not interact with human IgG.
    Temming AR, Dekkers G, van de Bovenkamp FS, Plomp HR, Bentlage AEH, Szittner Z, Derksen NIL, Wuhrer M, Rispens T, Vidarsson G., Free PMC Article

    10/24/2020
    FCER2 T2206C variant associated with FENO levels in asthmatic children using inhaled corticosteroids: The PACMAN study.

    FCER2 T2206C variant associated with FENO levels in asthmatic children using inhaled corticosteroids: The PACMAN study.
    Karimi L, Vijverberg SJH, Farzan N, Ghanbari M, Verhamme KMC, Maitland-van der Zee AH., Free PMC Article

    09/19/2020
    IgE-ICs are noninflammatory through reduced engagement by FcepsilonRI but increased targeting of the CD23 pathway.

    CD23 provides a noninflammatory pathway for IgE-allergen complexes.
    Engeroff P, Caviezel F, Mueller D, Thoms F, Bachmann MF, Vogel M.

    08/1/2020
    CD23 is associated with leukocytosis, a leukemic presentation, bone marrow involvement

    CD23 expression in mantle cell lymphoma is associated with CD200 expression, leukemic non-nodal form, and a better prognosis.
    Saksena A, Yin CC, Xu J, Li J, Zhou J, Wang SA, Lin P, Tang G, Wang L, Wang M, Miranda RN, Medeiros LJ, Li S.

    05/30/2020
    IL-3 transcriptionally regulates surface levels of Fcepsilon RI in human primary basophils.

    IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils.
    Zellweger F, Buschor P, Hobi G, Brigger D, Dahinden CA, Villiger PM, Eggel A., Free PMC Article

    11/30/2019
    these data confirm that CD23 protein is phosphorylated in B cells of B-CLL patients, report the identification of new CD23 phosphorylation sites, and suggest a possible role(s) of such phosphorylations in the activation of CD23 during the process of lymphocytic activation in B-CLL.

    Identification of new phosphorylation sites of CD23 in B-cells of patients with chronic lymphocytic leukemia.
    Maďarová M, Mucha R, Hresko S, Makarová Z, Gdovinová Z, Szilasiová J, Vitková M, Guman T, Štecová N, Dobransky T.

    05/11/2019
    The findings of our study indicate a positive association of circulating sCD23 level and B-NHL risks and highlight the possibility of sCD23 as a predictive marker of B cells non-Hodgkin's lymphomas.

    Elevated soluble CD23 level indicates increased risk of B cell non-Hodgkin's lymphomas: evidence from a meta-analysis.
    Huang YS, Zhou X, Yang ZF, Lv ZT.

    03/23/2019
    Data show that each IgE Fc is targeted by two single-domain antibodies (sdabs) having an epitope largely distinct from the FcepsilonRI binding site but overlapping significantly with the CD23-binding site.

    Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction.
    Jabs F, Plum M, Laursen NS, Jensen RK, Mølgaard B, Miehe M, Mandolesi M, Rauber MM, Pfützner W, Jakob T, Möbs C, Andersen GR, Spillner E., Free PMC Article

    03/10/2018
    Report a variant of t(14;18) negative nodal diffuse follicular lymphoma with CD23 expression, 1p36/TNFRSF14 abnormalities, and STAT6 mutations.

    Characterization of a variant of t(14;18) negative nodal diffuse follicular lymphoma with CD23 expression, 1p36/TNFRSF14 abnormalities, and STAT6 mutations.
    Siddiqi IN, Friedman J, Barry-Holson KQ, Ma C, Thodima V, Kang I, Padmanabhan R, Dias LM, Kelly KR, Brynes RK, Kamalakaran S, Houldsworth J.

    01/27/2018
    High CD23 expression is associated with B-cell Lymphoma.

    Biomarker Dynamics in B-cell Lymphoma: A Longitudinal Prospective Study of Plasma Samples Up to 25 Years before Diagnosis.
    Späth F, Wibom C, Krop EJ, Johansson AS, Bergdahl IA, Vermeulen R, Melin B.

    09/9/2017
    found a higher frequency of LIN1(-) CCR3(+) eosinophils, and decreased expression of CD23 and CD62L receptors in eosinophils of AD patients

    Impaired CD23 and CD62L expression and tissue inhibitors of metalloproteinases secretion by eosinophils in adults with atopic dermatitis.
    de Oliveira Titz T, Orfali RL, de Lollo C, Dos Santos VG, da Silva Duarte AJ, Sato MN, Aoki V.

    04/22/2017
    there is a high CD23a/CD23b ratio of chronic lymphocytic leukemia cells, which demonstrates that in a subset of CLL cases, low CD23 expression together with high CD20 and CD38 expressions may serve as a surrogate for trisomy 12

    Low CD23 expression correlates with high CD38 expression and the presence of trisomy 12 in CLL.
    Kriston C, Bödör C, Szenthe K, Bánáti F, Bánkuti B, Csernus B, Reiniger L, Csomor J, Matolcsy A, Barna G.

    04/1/2017
    Binding of CTLA4Fcepsilon to FcepsilonRII/CD23 appeared stronger than that of IgE

    CTLA4Fcε, a novel soluble fusion protein that binds B7 molecules and the IgE receptors, and reduces human in vitro soluble CD23 production and lymphocyte proliferation.
    Perez-Witzke D, Miranda-García MA, Suárez N, Becerra R, Duque K, Porras V, Fuenmayor J, Montano RF., Free PMC Article

    08/20/2016
    Human and murine P2X7 activation induces the rapid shedding of CD23 from B cells, with a potential role for ADAM10 in this process.

    Activation of the P2X7 receptor induces the rapid shedding of CD23 from human and murine B cells.
    Pupovac A, Geraghty NJ, Watson D, Sluyter R.

    09/5/2015
    Elevated serum sCD23 is associated with increased risk of non-Hodgkin lymphoma.

    Elevated serum sCD23 and sCD30 up to two decades prior to diagnosis associated with increased risk of non-Hodgkin lymphoma.
    Purdue MP, Lan Q, Kemp TJ, Hildesheim A, Weinstein SJ, Hofmann JN, Virtamo J, Albanes D, Pinto LA, Rothman N., Free PMC Article

    08/29/2015
    Data suggest that the protective immune response involving CD23-IgE-mediated nitric oxide release in cutaneous leishmaniasis (LCL).

    Protective Profile Involving CD23/IgE-mediated NO Release is a Hallmark of Cutaneous Leishmaniasis Patients from the Xakriabá Indigenous Community in Minas Gerais, Brazil.
    Carvalho-Gontijo R, Peruhype-Magalhães V, Costa-Silva MF, Martins-Filho OA, Quaresma PF, Freire Jde M, Moreno Ede C, Teixeira-Carvalho A, Gontijo CM.

    08/1/2015
    Crystal structure of the CD23-Fc3-4 complex with different molecular-packing constraints.

    A range of Cℇ3-Cℇ4 interdomain angles in IgE Fc accommodate binding to its receptor CD23.
    Dhaliwal B, Pang MO, Yuan D, Beavil AJ, Sutton BJ., Free PMC Article

    11/8/2014
    firstprevious page of 5 nextlast