| Hepatic Expression of NTN4 and Its Receptors in Patients with Hepatocellular Carcinoma. | Hepatic Expression of NTN4 and Its Receptors in Patients with Hepatocellular Carcinoma.
Vennela J, Pottakkat B, Vairappan BS, Verma SK, Mukherjee V., Free PMC Article | 01/16/2024 |
| Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis. | Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis.
Huang L, An X, Zhu Y, Zhang K, Xiao L, Yao X, Zeng X, Liang S, Yu J., Free PMC Article | 08/27/2022 |
| Delta40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity. | Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity.
Sun Y, Manceau A, Frydman L, Cappuccio L, Neves D, Basso V, Wang H, Fombonne J, Maisse C, Mehlen P, Paradisi A., Free PMC Article | 01/8/2022 |
| UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway. | UNC5B Promotes Vascular Endothelial Cell Senescence via the ROS-Mediated P53 Pathway.
Yang Z, Li H, Luo P, Yan D, Yang N, Zhang Y, Huang Y, Liu Y, Zhang L, Yan J, Zhang C., Free PMC Article | 01/1/2022 |
| UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53. | UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53.
Huang Y, Zhu Y, Zhang Z, Li Z, Kong C. | 12/25/2021 |
| Long non-coding RNA PITPNA-AS1 regulates UNC5B expression in papillary thyroid cancer via sponging miR-129-5p. | Long non-coding RNA PITPNA-AS1 regulates UNC5B expression in papillary thyroid cancer via sponging miR-129-5p.
Mei S, Zong H, Zhou H. | 11/27/2021 |
| The intracellular domain of UNC5B facilities proliferation and metastasis of bladder cancer cells. | The intracellular domain of UNC5B facilities proliferation and metastasis of bladder cancer cells.
Huang Y, Zhang Z, Miao M, Kong C., Free PMC Article | 09/25/2021 |
| A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis. | A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis.
Pradella D, Deflorian G, Pezzotta A, Di Matteo A, Belloni E, Campolungo D, Paradisi A, Bugatti M, Vermi W, Campioni M, Chiapparino A, Scietti L, Forneris F, Giampietro C, Volf N, Rehman M, Zacchigna S, Paronetto MP, Pistocchi A, Eichmann A, Mehlen P, Ghigna C., Free PMC Article | 08/28/2021 |
| LncRNA UNC5B-AS1 promotes malignant progression of prostate cancer by competitive binding to caspase-9. | LncRNA UNC5B-AS1 promotes malignant progression of prostate cancer by competitive binding to caspase-9.
Tan SF, Ni JX, Xiong H. | 03/20/2021 |
| Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease. | Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease.
Jiao X, Zhang D, Hong Q, Yan L, Han Q, Shao F, Cai G, Chen X, Zhu H. | 03/13/2021 |
| UNC-5 netrin receptor B regulates adipogenesis of human adipose-derived stem cells through JNK pathway. | UNC-5 netrin receptor B regulates adipogenesis of human adipose-derived stem cells through JNK pathway.
Hu X, Liu X, Lv L, Zhang X, Liu Y, Zhang P, Zhou Y. | 11/28/2020 |
| Polyomavirus Small T Antigen Induces Apoptosis in Mammalian Cells through the UNC5B Pathway in a PP2A-Dependent Manner. | Polyomavirus Small T Antigen Induces Apoptosis in Mammalian Cells through the UNC5B Pathway in a PP2A-Dependent Manner.
Bhat SA, Sarwar Z, Gillani SQ, Un Nisa M, Reshi I, Nabi N, Xie S, Fazili KM, Roberts TM, Andrabi S., Free PMC Article | 11/21/2020 |
| Netrin-1 and its receptor Unc5b may have essential roles in periodontal inflammation | Netrin-1 and its receptor Unc5b as markers of periodontal disease.
Gunpinar S, Meraci B, Dundar N. | 07/18/2020 |
| silencing of UNC5B, an NTN4 receptor, abrogated the NTN4-induced cellular activities of SEPCs in vitro and blood-flow recovery and neovascularization in vivo in ischemic muscle by reducing EPC homing and incorporation. | Ischemia-induced Netrin-4 promotes neovascularization through endothelial progenitor cell activation via Unc-5 Netrin receptor B.
Lee NG, Jeung IC, Heo SC, Song J, Kim W, Hwang B, Kwon MG, Kim YG, Lee J, Park JG, Shin MG, Cho YL, Son MY, Bae KH, Lee SH, Kim JH, Min JK. | 07/11/2020 |
| Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signaling. | Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling.
Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, Combémorel N, Riemenschneider C, Allègre N, Zhang J, Wajda P, Rama N, Vieugué P, Durand I, Brevet M, Gadot N, Imhof T, Merrill BJ, Koch M, Mehlen P, Chazaud C, Meissner A, Lavial F. | 04/25/2020 |
| UNC5B-AS1 plays an important role in tumourigenesis and metastasis of PTC and may be a potential therapeutic target for PTC. | The lncRNA UNC5B-AS1 promotes proliferation, migration, and invasion in papillary thyroid cancer cell lines.
Wang Y, Bhandari A, Niu J, Yang F, Xia E, Yao Z, Jin Y, Zheng Z, Lv S, Wang O. | 10/19/2019 |
| LncRNA TNRC6C-AS1 regulates UNC5B in thyroid cancer to influence cell proliferation, migration, and invasion as a competing endogenous RNA of miR-129-5p. | LncRNA TNRC6C-AS1 regulates UNC5B in thyroid cancer to influence cell proliferation, migration, and invasion as a competing endogenous RNA of miR-129-5p.
Hou S, Lin Q, Guan F, Lin C. | 10/12/2019 |
| Negative regulation of Naa10 towards NTN1 and its receptor UNC5B were also detected upon treatment of all-trans retinoid acid, which was often used to induce morphological differentiation. | Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-α-Acetyltransferase 10 (Naa10).
Xu H, Han Y, Liu B, Li R., Free PMC Article | 06/9/2018 |
| These findings point to a new important function of UNC5B and provide a potential basis for hASCs-mediated bone regeneration. | UNC-5 netrin receptor B mediates osteogenic differentiation by modulating bone morphogenetic protein signaling in human adipose-derived stem cells.
Hu X, Liu Y, Zhang M, Wang Y, Lv L, Zhang X, Zhang P, Zhou Y. | 12/30/2017 |
| Our results suggest that UNC5B overexpression inhibits the proliferation and migration of bladder cancer cells by inducing cell cycle arrest at G2/M phase. | Overexpression of UNC5B in bladder cancer cells inhibits proliferation and reduces the volume of transplantation tumors in nude mice.
Kong C, Zhan B, Piao C, Zhang Z, Zhu Y, Li Q., Free PMC Article | 09/30/2017 |
| UNC5B expression is decreased in bladder cancer cells compared to normal bladder cell lines. | PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer.
Liu J, Kong CZ, Gong DX, Zhang Z, Zhu YY., Free PMC Article | 11/8/2014 |
| Data indicate that dysregulation of expression of netrin-1 NTN1 in smooth muscle cell (SMC) and its chemorepulsive receptor UNC5B in macrophages are involved in the development of atherosclerosis and unstable plaques. | Association of neuroimmune guidance cue netrin-1 and its chemorepulsive receptor UNC5B with atherosclerotic plaque expression signatures and stability in human(s): Tampere Vascular Study (TVS).
Oksala N, Pärssinen J, Seppälä I, Raitoharju E, Kholova I, Hernesniemi J, Lyytikäinen LP, Levula M, Mäkelä KM, Sioris T, Kähönen M, Laaksonen R, Hytönen V, Lehtimäki T. | 08/16/2014 |
| unc5b expression is greater in adipose tissue of obese versus lean subjects. | Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Ramkhelawon B, Hennessy EJ, Ménager M, Ray TD, Sheedy FJ, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner KJ, Moore KJ., Free PMC Article | 05/31/2014 |
| Higher netrin-1 and lower UNC5B expression in all prostate carcinoma cell lines indicated that netrin-1 and UNC5B could be used to predict metastasis. | Interactional expression of netrin-1 and its dependence receptor UNC5B in prostate carcinoma.
Kong CZ, Liu J, Liu L, Zhang Z, Guo KF. | 11/30/2013 |
| Low UNC5B expression was an independent risk factor for postoperative recurrence in patients with different stages and grades bladder cancer. | Clinical significance of UNC5B expression in bladder cancer.
Liu J, Zhang Z, Li ZH, Kong CZ. | 09/28/2013 |