| Microbial chaperonin 60 inhibits osteoclast differentiation by interfering with RANK/RANKL binding and overexpression of lipocalin2. | Microbial chaperonin 60 inhibits osteoclast differentiation by interfering with RANK/RANKL binding and overexpression of lipocalin2.
Cho JY, Woo HE, Yeom J, An M, Ma S, Yim DJ, Kim SH, Lim YH. | 10/25/2024 |
| 14-3-3zeta suppresses RANKL signaling by destabilizing TRAF6. | 14-3-3ζ suppresses RANKL signaling by destabilizing TRAF6.
Ayyasamy R, Fan S, Czernik P, Lecka-Czernik B, Chattopadhyay S, Chakravarti R., Free PMC Article | 07/29/2024 |
| Rankl genetic deficiency and functional blockade undermine skeletal stem and progenitor cell differentiation. | Rankl genetic deficiency and functional blockade undermine skeletal stem and progenitor cell differentiation.
Schiavone ML, Crisafulli L, Camisaschi C, De Simone G, Liberati FR, Palagano E, Rucci N, Ficara F, Sobacchi C., Free PMC Article | 07/18/2024 |
| Characterization of a spontaneous osteopetrosis model using RANKL-dysfunctional mice. | Characterization of a spontaneous osteopetrosis model using RANKL-dysfunctional mice.
Kim BC, Lee G, Jang Y, Kim DO, Ju J, Lee CM, Lim W. | 06/28/2024 |
| Ctdnep1 phosphatase is required for negative regulation of RANKL-induced osteoclast differentiation in RAW264.7 cells. | Ctdnep1 phosphatase is required for negative regulation of RANKL-induced osteoclast differentiation in RAW264.7 cells.
Konno T, Murachi H, Otsuka K, Kimura Y, Sampei C, Arasaki Y, Kohara Y, Hayata T. | 06/11/2024 |
| Accumulation of gammadeltaT cells in the decidua is promoted by RANKL which upregulates ICAM-1 via NF-kappaB. | Accumulation of γδT cells in the decidua is promoted by RANKL which upregulates ICAM-1 via NF-κB.
Chang RQ, Dai JC, Qiu YH, Liang Y, Hu XY, Li MQ, He F. | 05/22/2024 |
| Osteocyte RANKL Drives Bone Resorption in Mouse Ligature-Induced Periodontitis. | Osteocyte RANKL Drives Bone Resorption in Mouse Ligature-Induced Periodontitis.
Kittaka M, Yoshimoto T, Levitan ME, Urata R, Choi RB, Teno Y, Xie Y, Kitase Y, Prideaux M, Dallas SL, Robling AG, Ueki Y., Free PMC Article | 05/21/2024 |
| Dysfunction of poly (ADP-ribose) glycohydrolase suppresses osteoclast differentiation in RANKL-stimulated RAW264 cells. | Dysfunction of poly (ADP-ribose) glycohydrolase suppresses osteoclast differentiation in RANKL-stimulated RAW264 cells.
Sasaki Y, Nakatsuka R, Inoue A, Inouchi T, Masutani M, Nozaki T. | 01/11/2024 |
| The effect of osteocyte-derived RANKL on bone graft remodeling: An in vivo experimental study. | The effect of osteocyte-derived RANKL on bone graft remodeling: An in vivo experimental study.
Feher B, Kampleitner C, Heimel P, Tangl S, Helms JA, Kuchler U, Gruber R. | 12/20/2023 |
| RANKL/RANK is required for cytokine-induced beta cell death; osteoprotegerin, a RANKL inhibitor, reverses rodent type 1 diabetes. | RANKL/RANK is required for cytokine-induced beta cell death; osteoprotegerin, a RANKL inhibitor, reverses rodent type 1 diabetes.
Kondegowda NG, Filipowska J, Do JS, Leon-Rivera N, Li R, Hampton R, Ogyaadu S, Levister C, Penninger JM, Reijonen H, Levy CJ, Vasavada RC., Free PMC Article | 11/3/2023 |
| Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation. | Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation.
Miyagawa K, Tenshin H, Mulcrone PL, Delgado-Calle J, Subler MA, Windle JJ, Chirgwin JM, Roodman GD, Kurihara N., Free PMC Article | 07/27/2023 |
| RANKL Inhibition Reduces Cardiac Hypertrophy in mdx Mice and Possibly in Children with Duchenne Muscular Dystrophy. | RANKL Inhibition Reduces Cardiac Hypertrophy in mdx Mice and Possibly in Children with Duchenne Muscular Dystrophy.
Marcadet L, Juracic ES, Khan N, Bouredji Z, Yagita H, Ward LM, Tupling AR, Argaw A, Frenette J., Free PMC Article | 06/14/2023 |
| USP53 Regulates Bone Homeostasis by Controlling Rankl Expression in Osteoblasts and Bone Marrow Adipocytes. | USP53 Regulates Bone Homeostasis by Controlling Rankl Expression in Osteoblasts and Bone Marrow Adipocytes.
Hariri H, Kose O, Bezdjian A, Daniel SJ, St-Arnaud R. | 04/14/2023 |
| Crucial Role of Lysine-Specific Histone Demethylase 1 in RANKL-Mediated Osteoclast Differentiation. | Crucial Role of Lysine-Specific Histone Demethylase 1 in RANKL-Mediated Osteoclast Differentiation.
Ding M, Chen Z, Cho E, Park SW, Lee TH., Free PMC Article | 03/21/2023 |
| RANKL up-regulated by progesterone aggravates lipopolysaccharide-induced acute lung injury during pregnancy. | RANKL up-regulated by progesterone aggravates lipopolysaccharide-induced acute lung injury during pregnancy.
Lai ZZ, Zhou WJ, Shi JW, Meng YH, Wu JN, Ye JF, Peng T, Xu CE, Li MQ. | 01/28/2023 |
| Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus. | Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus.
Szwarc MM, Hai L, Maurya VK, Rajapakshe K, Perera D, Ittmann MM, Mo Q, Lin Y, Bettini ML, Coarfa C, Lydon JP., Free PMC Article | 10/22/2022 |
| Hexokinase 2-mediated glycolysis promotes receptor activator of NF-kappaB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts. | Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Yu Y, Jiang L, Li J, Lei L, Li H. | 08/6/2022 |
| Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice. | Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice.
Shin HR, Kim BS, Kim HJ, Yoon H, Kim WJ, Choi JY, Ryoo HM., Free PMC Article | 05/14/2022 |
| Potential mechanisms of osteoprotegerin-induced damage to osteoclast adhesion structures via P2X7R-mediated MAPK signaling. | Potential mechanisms of osteoprotegerin-induced damage to osteoclast adhesion structures via P2X7R-mediated MAPK signaling.
Ma Y, Shi X, Zhao H, Song R, Zou H, Zhu J, Liu Z., Free PMC Article | 04/16/2022 |
| Serial Passaging of RAW 264.7 Cells Modulates Intracellular AGE Formation and Downregulates RANKL-Induced In Vitro Osteoclastogenesis. | Serial Passaging of RAW 264.7 Cells Modulates Intracellular AGE Formation and Downregulates RANKL-Induced In Vitro Osteoclastogenesis.
Lucy TT, Mamun-Or-Rashid ANM, Yagi M, Yonei Y., Free PMC Article | 03/26/2022 |
| Group 2 innate lymphoid cells in bone marrow regulate osteoclastogenesis in a reciprocal manner via RANKL, GM-CSF and IL-13. | Group 2 innate lymphoid cells in bone marrow regulate osteoclastogenesis in a reciprocal manner via RANKL, GM-CSF and IL-13.
Momiuchi Y, Motomura Y, Suga E, Mizuno H, Kikuta J, Morimoto A, Mochizuki M, Otaki N, Ishii M, Moro K. | 02/19/2022 |
| MYC-mediated miR-320a affects receptor activator of nuclear factor kappaB ligand (RANKL)-induced osteoclast formation by regulating phosphatase and tensin homolog (PTEN). | MYC-mediated miR-320a affects receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast formation by regulating phosphatase and tensin homolog (PTEN).
Chen H, Li S, Yin H, Hua Z, Shao Y, Wei J, Wang J., Free PMC Article | 02/19/2022 |
| Euphoesulatin A prevents osteoclast differentiation and bone loss via inhibiting RANKL-induced ROS production and NF-kappaB and MAPK signal pathways. | Euphoesulatin A prevents osteoclast differentiation and bone loss via inhibiting RANKL-induced ROS production and NF-κB and MAPK signal pathways.
Zhang YT, Hu C, Zhang SX, Zhou HH, Xu J, Ma JD, Dai L, Gu Q. | 02/19/2022 |
| Yukmijihwang-Tang Suppresses Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-Induced Osteoclast Differentiation and Prevents Ovariectomy (OVX)-Mediated Bone Loss. | Yukmijihwang-Tang Suppresses Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-Induced Osteoclast Differentiation and Prevents Ovariectomy (OVX)-Mediated Bone Loss.
Han SY, Kim YK., Free PMC Article | 02/12/2022 |
| Interleukin 19 suppresses RANKL-induced osteoclastogenesis via the inhibition of NF-kappaB and p38MAPK activation and c-Fos expression in RAW264.7 cells. | Interleukin 19 suppresses RANKL-induced osteoclastogenesis via the inhibition of NF-κB and p38MAPK activation and c-Fos expression in RAW264.7 cells.
Tsubaki M, Takeda T, Matsuda T, Yamamoto Y, Higashinaka A, Yamamoto K, Tsurushima K, Ishizaka T, Nishida S. | 02/5/2022 |