FASN contributes to ADM resistance of diffuse large B-cell lymphoma by inhibiting ferroptosis via nf-κB/STAT3/GPX4 axis.
Zhong X, Zhang W, Zhang W, Yu N, Li W, Song X., Free PMC Article

2-Deoxy-D-Glucose Downregulates Fatty Acid Synthase Gene Expression Via an Endoplasmic Reticulum Stress-Dependent Pathway in HeLa Cells.
Harada N, Yoshikatsu A, Yamamoto H, Nakaya Y.

Deficiency of SIAH1 promotes the formation of filopodia by increasing the accumulation of FASN in liver cancer.
Liu Z, Hu Q, Cao K, Sun J, Cui L, Ji M, Shan W, Yang W, Zhang G, Tian Z, Shi H, Zhang B, Wang R., Free PMC Article

Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer.
Papulino C, Chianese U, Ali A, Favale G, Tuccillo C, Ciardiello F, Di Mauro A, Mignogna C, Ferrara G, Budillon A, Megchelenbrink WL, Del Gaudio N, Conte M, Merciai F, Campiglia P, Altucci L, Carafa V, Sommella E, Benedetti R., Free PMC Article

FASN regulates STING palmitoylation via malonyl-CoA in macrophages to alleviate sepsis-induced liver injury.
Kang J, Wu J, Liu Q, Jiang H, Li W, Li Y, Li X, Ni C, Wu L, Liu M, Liu H, Deng L, Lin Z, Wu X, Zhao Y, Ren J.

Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27(KIP1) Regulation.
Cigliano A, Simile MM, Vidili G, Pes GM, Dore MP, Urigo F, Cossu E, Che L, Feo C, Steinmann SM, Ribback S, Pascale RM, Evert M, Chen X, Calvisi DF., Free PMC Article

DPP3 promotes breast cancer tumorigenesis by stabilizing FASN and promoting lipid synthesis.
Fu X, Li X, Wang W, Li J., Free PMC Article

Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth.
Drury J, Geisen ME, Tessmann JW, Rychahou PG, Kelson CO, He D, Wang C, Evers BM, Zaytseva YY., Free PMC Article

The Role of Fatty Acid Synthase in the Vascular Smooth Muscle Cell to Foam Cell Transition.
Bogan BJ, Williams HC, Holden CM, Patel V, Joseph G, Fierro C, Sepulveda H, Taylor WR, Rezvan A, San Martin A., Free PMC Article

The Regulation of Fatty Acid Synthase by Exosomal miR-143-5p and miR-342-5p in Idiopathic Pulmonary Fibrosis.
Hayek H, Rehbini O, Kosmider B, Brandt T, Chatila W, Marchetti N, Criner GJ, Bolla S, Kishore R, Bowler RP, Bahmed K.,

FAS/SREBP-1c contributes to colorectal carcinogenesis through calcium signaling pathway and cAMP signaling pathway.
Xu Y, Hu H, An J, Zong L.

The m(6)A modification mediated-lncRNA POU6F2-AS1 reprograms fatty acid metabolism and facilitates the growth of colorectal cancer via upregulation of FASN.
Jiang T, Qi J, Xue Z, Liu B, Liu J, Hu Q, Li Y, Ren J, Song H, Xu Y, Xu T, Fan R, Song J., Free PMC Article

FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma.
Huang J, Tsang WY, Fang XN, Zhang Y, Luo J, Gong LQ, Zhang BF, Wong CN, Li ZH, Liu BL, Huang JL, Yang YM, Liu S, Ban LX, Chan YH, Guan XY.

GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Chen Y, Feng Y, Lin Y, Zhou X, Wang L, Zhou Y, Lin K, Cai L., Free PMC Article

PITPNC1 Suppress CD8(+) T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155.
Liang J, Liao L, Xie L, Tang W, Yu X, Lu Y, Chen H, Xu J, Sun L, Wu H, Cui C, Tan Y., Free PMC Article

FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-genomic Features of Prostate Cancer.
Dairo O, DePaula Oliveira L, Schaffer E, Vidotto T, Mendes AA, Lu J, Huynh SV, Hicks J, Sowalsky AG, De Marzo AM, Joshu CE, Hanratty B, Sfanos KS, Isaacs WB, Haffner MC, Lotan TL., Free PMC Article

Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer.
Zhou L, Du K, Dai Y, Zeng Y, Luo Y, Ren M, Pan W, Liu Y, Zhang L, Zhu R, Feng D, Tian F, Gu C., Free PMC Article

Differential Sperm Proteomics Reveals the Significance of Fatty Acid Synthase and Clusterin in Idiopathic Recurrent Pregnancy Loss.
Thapliyal A, Tomar AK, Chandra KB, Naglot S, Dhiman S, Singh N, Sharma JB, Yadav S.

Mitochondrial pyruvate carrier 1 regulates fatty acid synthase lactylation and mediates treatment of nonalcoholic fatty liver disease.
Gao R, Li Y, Xu Z, Zhang F, Xu J, Hu Y, Yin J, Yang K, Sun L, Wang Q, He X, Huang K.

BCAT2 promotes melanoma progression by activating lipogenesis via the epigenetic regulation of FASN and ACLY expressions.
Tian Y, Ma J, Wang H, Yi X, Wang H, Zhang H, Guo S, Yang Y, Zhang B, Du J, Shi Q, Gao T, Guo W, Li C., Free PMC Article

Sex differences in FASN protein concentrations in urinary exosomes related to serum triglycerides levels in healthy adults.
Li T, Meng W, Liu TC, Wang YZ, Zhang M., Free PMC Article

Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.
Hasan SMN, Lou JW, Keszei AFA, Dai DL, Mazhab-Jafari MT., Free PMC Article

Overexpression of fatty acid synthase attenuates bleomycin induced lung fibrosis by restoring mitochondrial dysfunction in mice.
Shin H, Park S, Hong J, Baek AR, Lee J, Kim DJ, Jang AS, Chin SS, Jeong SH, Park SW., Free PMC Article

EIF4A3-induced circZFAND6 promotes breast cancer proliferation and metastasis through the miR-647/FASN axis.
Huang X, Tan W, Liu Z, Fu X, Li Z, Lai S, Li Q, Zhong X, Qu F, Zhang H, Li H.

FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth.
Wei W, Qin B, Wen W, Zhang B, Luo H, Wang Y, Xu H, Xie X, Liu S, Jiang X, Wang M, Tang Q, Zhang J, Yang R, Fan Z, Lyu H, Lin J, Li K, Lee MH., Free PMC Article