| TRIM28 Fosters Microglia Ferroptosis via Autophagy Modulation to Enhance Neuropathic Pain and Neuroinflammation. | TRIM28 Fosters Microglia Ferroptosis via Autophagy Modulation to Enhance Neuropathic Pain and Neuroinflammation.
Tang J, Chen Q, Xiang L, Tu T, Zhang Y, Ou C. | 10/25/2024 |
| TIF1beta activates leukemic transcriptional program in HSCs and promotes BCR::ABL1-induced myeloid leukemia. | TIF1β activates leukemic transcriptional program in HSCs and promotes BCR::ABL1-induced myeloid leukemia.
Morii M, Kubota S, Iimori M, Yokomizo-Nakano T, Hamashima A, Bai J, Nishimura A, Tasaki M, Ando Y, Araki K, Sashida G. | 10/7/2024 |
| Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis. | Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis.
Lin KH, Hibbert JE, Flynn CG, Lemens JL, Torbey MM, Steinert ND, Flejsierowicz PM, Melka KM, Lindley GT, Lares M, Setaluri V, Wagers AJ, Hornberger TA., Free PMC Article | 09/18/2024 |
| The correlation between TRIM28 expression and immune checkpoints in CRPC. | The correlation between TRIM28 expression and immune checkpoints in CRPC.
Xue D, Zuo Q, Chang J, Wu X. | 07/29/2024 |
| Heat shock protein gp96 drives natural killer cell maturation and anti-tumor immunity by counteracting Trim28 to stabilize Eomes. | Heat shock protein gp96 drives natural killer cell maturation and anti-tumor immunity by counteracting Trim28 to stabilize Eomes.
Xu Y, Li X, Cheng F, Zhao B, Fang M, Li Z, Meng S., Free PMC Article | 02/14/2024 |
| Co-option of endogenous retroviruses through genetic escape from TRIM28 repression. | Co-option of endogenous retroviruses through genetic escape from TRIM28 repression.
Enriquez-Gasca R, Gould PA, Tunbak H, Conde L, Herrero J, Chittka A, Beck CR, Gifford R, Rowe HM. | 10/12/2023 |
| Loss of Trim28 in muscle alters mitochondrial signalling but not systemic metabolism. | Loss of Trim28 in muscle alters mitochondrial signalling but not systemic metabolism.
King EJ, Bond ST, Yang C, Liu Y, Calkin AC, Henstridge DC, Drew BG. | 10/10/2023 |
| TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance. | TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance.
Ma X, Jia S, Wang G, Liang M, Guo T, Du H, Li S, Li X, Huangfu L, Guo J, Xing X, Ji J., Free PMC Article | 06/29/2023 |
| Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx. | Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.
Liu C, Zhao K, Chen Y, Yao Y, Tang J, Wang J, Xu C, Yang Q, Zheng Y, Yuan Y, Sun H, Zhang Y, Zhou Y, Chen J, Wang Y, Wu C, Pei R, Chen X., Free PMC Article | 06/2/2023 |
| TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy. | TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy.
Song T, Lv S, Ma X, Zhao X, Fan L, Zou Q, Li N, Yan Y, Zhang W, Sun L., Free PMC Article | 06/1/2023 |
| TRIM28 promotes luminal cell plasticity in a mouse model of prostate cancer. | TRIM28 promotes luminal cell plasticity in a mouse model of prostate cancer.
Yende AS, Williams EC, Pletcher A, Helfand A, Ibeawuchi H, North TM, Latham PS, Horvath A, Shibata M., Free PMC Article | 04/27/2023 |
| Trim28 citrullination maintains mouse embryonic stem cell pluripotency via regulating Nanog and Klf4 transcription. | Trim28 citrullination maintains mouse embryonic stem cell pluripotency via regulating Nanog and Klf4 transcription.
Zhang Y, Wan X, Qiu L, Zhou L, Huang Q, Wei M, Liu X, Liu S, Zhang B, Han J. | 03/27/2023 |
| TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis. | TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis.
Liu H, Liu Y, Jin SG, Johnson J, Xuan H, Lu D, Li J, Zhai L, Li X, Zhao Y, Liu M, Craig SEL, Floramo JS, Molchanov V, Li J, Li JD, Krawczyk C, Shi X, Pfeifer GP, Yang T., Free PMC Article | 02/13/2023 |
| TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway. | TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.
Rossitto M, Déjardin S, Rands CM, Le Gras S, Migale R, Rafiee MR, Neirijnck Y, Pruvost A, Nguyen AL, Bossis G, Cammas F, Le Gallic L, Wilhelm D, Lovell-Badge R, Boizet-Bonhoure B, Nef S, Poulat F., Free PMC Article | 08/13/2022 |
| Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function. | Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function.
Steinert ND, Potts GK, Wilson GM, Klamen AM, Lin KH, Hermanson JB, McNally RM, Coon JJ, Hornberger TA., Free PMC Article | 01/29/2022 |
| LARP7 Suppresses Endothelial-to-Mesenchymal Transition by Coupling With TRIM28. | LARP7 Suppresses Endothelial-to-Mesenchymal Transition by Coupling With TRIM28.
Liang X, Wu S, Geng Z, Liu L, Zhang S, Wang S, Zhang Y, Huang Y, Zhang B. | 01/15/2022 |
| Kap1 regulates the self-renewal of embryonic stem cells and cellular reprogramming by modulating Oct4 protein stability. | Kap1 regulates the self-renewal of embryonic stem cells and cellular reprogramming by modulating Oct4 protein stability.
Do EK, Moon HJ, Kang KT, Yoon JW, Kim YS, Seo JK, Kim JH., Free PMC Article | 12/18/2021 |
| Activation of endogenous retroviruses during brain development causes an inflammatory response. | Activation of endogenous retroviruses during brain development causes an inflammatory response.
Jönsson ME, Garza R, Sharma Y, Petri R, Södersten E, Johansson JG, Johansson PA, Atacho DA, Pircs K, Madsen S, Yudovich D, Ramakrishnan R, Holmberg J, Larsson J, Jern P, Jakobsson J., Free PMC Article | 11/6/2021 |
| TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus. | TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus.
Chikuma S, Yamanaka S, Nakagawa S, Ueda MT, Hayabuchi H, Tokifuji Y, Kanayama M, Okamura T, Arase H, Yoshimura A. | 08/28/2021 |
| TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation. | TRIM28 SUMOylates and stabilizes NLRP3 to facilitate inflammasome activation.
Qin Y, Li Q, Liang W, Yan R, Tong L, Jia M, Zhao C, Zhao W., Free PMC Article | 08/28/2021 |
| Phosphorylation of the HP1beta hinge region sequesters KAP1 in heterochromatin and promotes the exit from naive pluripotency. | Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency.
Qin W, Ugur E, Mulholland CB, Bultmann S, Solovei I, Modic M, Smets M, Wierer M, Forné I, Imhof A, Cardoso MC, Leonhardt H., Free PMC Article | 08/14/2021 |
| KAP1-associated transcriptional inhibitory complex regulates C2C12 myoblasts differentiation and mitochondrial biogenesis via miR-133a repression. | KAP1-associated transcriptional inhibitory complex regulates C2C12 myoblasts differentiation and mitochondrial biogenesis via miR-133a repression.
Zhang J, Hua C, Zhang Y, Wei P, Tu Y, Wei T., Free PMC Article | 05/1/2021 |
| Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia. | Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia.
Tan JHL, Wollmann H, van Pelt AMM, Kaldis P, Messerschmidt DM., Free PMC Article | 04/17/2021 |
| TRIM28 Regulates Dlk1 Expression in Adipogenesis. | TRIM28 Regulates Dlk1 Expression in Adipogenesis.
Lu HP, Lin CJ, Chen WC, Chang YJ, Lin SW, Wang HH, Chang CJ., Free PMC Article | 02/27/2021 |
| Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance. | Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance.
Bond ST, King EJ, Henstridge DC, Tran A, Moody SC, Yang C, Liu Y, Mellett NA, Nath AP, Inouye M, Tarling EJ, de Aguiar Vallim TQ, Meikle PJ, Calkin AC, Drew BG., Free PMC Article | 01/16/2021 |