| Genotype and phenotype correlation of PHACTR1-related neurological disorders. | Genotype and phenotype correlation of PHACTR1-related neurological disorders.
Xu Z, Sadleir L, Goel H, Jiao X, Niu Y, Zhou Z, de Valles-Ibáñez G, Poke G, Hildebrand M, Lieffering N, Qin J, Yang Z. | 05/29/2024 |
| Endothelial PHACTR1 Promotes Endothelial Activation and Atherosclerosis by Repressing PPARgamma Activity Under Disturbed Flow in Mice. | Endothelial PHACTR1 Promotes Endothelial Activation and Atherosclerosis by Repressing PPARγ Activity Under Disturbed Flow in Mice.
Jiang D, Liu H, Zhu G, Li X, Fan L, Zhao F, Xu C, Wang S, Rose Y, Rhen J, Yu Z, Yin Y, Gu Y, Xu X, Fisher EA, Ge J, Xu Y, Pang J., Free PMC Article | 07/31/2023 |
| PHACTR1, a coronary artery disease risk gene, mediates endothelial dysfunction. | PHACTR1, a coronary artery disease risk gene, mediates endothelial dysfunction.
Ma X, Su M, He Q, Zhang Z, Zhang F, Liu Z, Sun L, Weng J, Xu S., Free PMC Article | 10/1/2022 |
| PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice. | PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice.
Rubin S, Bougaran P, Martin S, Abelanet A, Delobel V, Pernot M, Jeanningros S, Bats ML, Combe C, Dufourcq P, Debette S, Couffinhal T, Duplàa C. | 05/7/2022 |
| PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice. | PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice.
Messerschmidt C, Foddis M, Blumenau S, Müller S, Bentele K, Holtgrewe M, Kun-Rodrigues C, Alonso I, do Carmo Macario M, Morgadinho AS, Velon AG, Santo G, Santana I, Mönkäre S, Kuuluvainen L, Schleutker J, Pöyhönen M, Myllykangas L, Senatore A, Berchtold D, Winek K, Meisel A, Pavlovic A, Kostic V, Dobricic V, Lohmann E, Hanagasi H, Guven G, Bilgic B, Bras J, Guerreiro R, Beule D, Dirnagl U, Sassi C., Free PMC Article | 10/16/2021 |
| Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis. | Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis.
Kasikara C, Schilperoort M, Gerlach B, Xue C, Wang X, Zheng Z, Kuriakose G, Dorweiler B, Zhang H, Fredman G, Saleheen D, Reilly MP, Tabas I., Free PMC Article | 10/2/2021 |
| Genetic deficiency of Phactr1 promotes atherosclerosis development via facilitating M1 macrophage polarization and foam cell formation. | Genetic deficiency of Phactr1 promotes atherosclerosis development via facilitating M1 macrophage polarization and foam cell formation.
Li T, Ding L, Wang Y, Yang O, Wang S, Kong J. | 03/28/2021 |
| Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme. | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Fedoryshchak RO, Přechová M, Butler AM, Lee R, O'Reilly N, Flynn HR, Snijders AP, Eder N, Ultanir S, Mouilleron S, Treisman R., Free PMC Article | 02/27/2021 |
| that Phactr1 takes part in neuronal functions regulated in a spatiotemporal manner | Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.
Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI. | 08/25/2018 |
| It has been demonstrated that PHACTR1 gene expression increases with the progression of vascular calcification and that regulation of PHACTR1 in smooth muscle cells modulates the severity of vascular calcification. | Coronary artery disease associated gene Phactr1 modulates severity of vascular calcification in vitro.
Aherrahrou R, Aherrahrou Z, Schunkert H, Erdmann J. | 09/2/2017 |
| This study demonistrated that Phactr1 appeared to be expressed in post-mitotic neurons in developmental brain. | Different expression patterns of Phactr family members in normal and injured mouse brain.
Kim JY, Choi SY, Moon Y, Kim HJ, Chin JH, Kim H, Sun W. | 01/26/2013 |