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    Tgfbr2 transforming growth factor, beta receptor II [ Mus musculus (house mouse) ]

    Gene ID: 21813, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Impaired Tertiary Dentin Secretion after Shallow Injury in Tgfbr2-Deficient Dental Pulp Cells Is Rescued by Extended CGRP Signaling.

    Impaired Tertiary Dentin Secretion after Shallow Injury in Tgfbr2-Deficient Dental Pulp Cells Is Rescued by Extended CGRP Signaling.
    Stanwick M, Fenesha F, Hamid A, Kang K, Kanniard D, Kim I, Mandarano N, Schumacher FL, Peters SB., Free PMC Article

    08/9/2024
    Long non-coding RNA H19 promotes myoblast fibrogenesis via regulating the miR-20a-5p-Tgfbr2 axis.

    Long non-coding RNA H19 promotes myoblast fibrogenesis via regulating the miR-20a-5p-Tgfbr2 axis.
    Lin J, Luo Z, Liu S, Chen Q, Liu S, Chen J.

    07/26/2024
    Long Non-Coding RNA Mir17hg Positively Regulates Melanogenesis by Inhibiting TGFbeta Receptor 2 under Psychological Stress.

    Long Non-Coding RNA Mir17hg Positively Regulates Melanogenesis by Inhibiting TGFβ Receptor 2 under Psychological Stress.
    Dong J, Peng Z, Chen M, Lai Y, Zhang X, Yu M, Zhong H, Liu J, Yue Y, Shang J.

    01/27/2024
    Transforming growth factor beta receptor 2 (Tgfbr2) deficiency in keratocytes results in corneal ectasia.

    Transforming growth factor beta receptor 2 (Tgfbr2) deficiency in keratocytes results in corneal ectasia.
    Wang YC, Zolnik OB, Yasoda S, Yeh LK, Yuan Y, Kao W, Saika S, Liu CY.

    09/8/2023
    miR-17-5p slows progression of hepatocellular carcinoma by downregulating TGFbetaR2.

    miR-17-5p slows progression of hepatocellular carcinoma by downregulating TGFβR2.
    Liu HT, Luo CP, Jiang MJ, Deng ZJ, Teng YX, Su JY, Pan LX, Ma L, Guo PP, Zhong JH.

    08/30/2023
    SPSB1-mediated inhibition of TGF-beta receptor-II impairs myogenesis in inflammation.

    SPSB1-mediated inhibition of TGF-β receptor-II impairs myogenesis in inflammation.
    Li Y, Dörmann N, Brinschwitz B, Kny M, Martin E, Bartels K, Li N, Giri PV, Schwanz S, Boschmann M, Hille S, Fielitz B, Wollersheim T, Grunow J, Felix SB, Weber-Carstens S, Luft FC, Müller OJ, Fielitz J., Free PMC Article

    08/9/2023
    Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow.

    Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow.
    Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD, Mason JC, Randi AM, Ahluwalia A, Raimondi C., Free PMC Article

    05/31/2023
    Depletion of Tgfbr2 in hepatocytes alleviates liver fibrosis and restores hepatic function in fibrotic mice.

    Depletion of Tgfbr2 in hepatocytes alleviates liver fibrosis and restores hepatic function in fibrotic mice.
    Liu SQ, Deng X, Zhu CP, Cui YL, Xie WF, Zhang X.

    05/12/2023
    Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-beta receptor II.

    Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II.
    Ni JY, Wang X, Xie HY, Yang NH, Li JY, Sun XA, Guo HJ, Zhou L, Zhang W, Liu J, Lu LM., Free PMC Article

    03/2/2023
    Loss of MMR and TGFBR2 Increases the Susceptibility to Microbiota-Dependent Inflammation-Associated Colon Cancer.

    Loss of MMR and TGFBR2 Increases the Susceptibility to Microbiota-Dependent Inflammation-Associated Colon Cancer.
    Tosti E, Almeida AS, Tran TTT, Barbachan E Silva M, Broin PÓ, Dubin R, Chen K, Beck AP, Mclellan AS, Vilar E, Golden A, O'Toole PW, Edelmann W., Free PMC Article

    09/3/2022
    SMAD4 and TGFbeta are architects of inverse genetic programs during fate determination of antiviral CTLs.

    SMAD4 and TGFβ are architects of inverse genetic programs during fate determination of antiviral CTLs.
    Chandiran K, Suarez-Ramirez JE, Hu Y, Jellison ER, Ugur Z, Low JS, McDonald B, Kaech SM, Cauley LS., Free PMC Article

    09/3/2022
    Blockade of TGF-beta (Transforming Growth Factor Beta) Signaling by Deletion of Tgfbr2 in Smooth Muscle Cells of 11-Month-Old Mice Alters Aortic Structure and Causes Vasomotor Dysfunction-Brief Report.

    Blockade of TGF-β (Transforming Growth Factor Beta) Signaling by Deletion of Tgfbr2 in Smooth Muscle Cells of 11-Month-Old Mice Alters Aortic Structure and Causes Vasomotor Dysfunction-Brief Report.
    Lee CY, Angelov SN, Zhu J, Bi L, Sanford N, Alp Yildirim I, Dichek DA., Free PMC Article

    06/11/2022
    Dexamethasone attenuated thoracic aortic aneurysm and dissection in vascular smooth muscle cell Tgfbr2-disrupted mice with CCL8 suppression.

    Dexamethasone attenuated thoracic aortic aneurysm and dissection in vascular smooth muscle cell Tgfbr2-disrupted mice with CCL8 suppression.
    Wang X, Li Q, Li W, Zhang T, Li X, Jiao Y, Zhang X, Jiang J, Zhang X, Zhang X.

    06/11/2022
    Inhibition of Integrin alphavbeta6 Activation of TGF-beta Attenuates Tendinopathy.

    Inhibition of Integrin αvβ6 Activation of TGF-β Attenuates Tendinopathy.
    Wang X, Liu S, Yu T, An S, Deng R, Tan X, Crane J, Zhang W, Pan D, Wan M, Carr A, Cao X., Free PMC Article

    04/23/2022
    CCN2 Increases TGF-beta Receptor Type II Expression in Vascular Smooth Muscle Cells: Essential Role of CCN2 in the TGF-beta Pathway Regulation.

    CCN2 Increases TGF-β Receptor Type II Expression in Vascular Smooth Muscle Cells: Essential Role of CCN2 in the TGF-β Pathway Regulation.
    Tejera-Muñoz A, Marquez-Exposito L, Tejedor-Santamaría L, Rayego-Mateos S, Orejudo M, Suarez-Álvarez B, López-Larrea C, Ruíz-Ortega M, Rodrigues-Díez RR., Free PMC Article

    02/12/2022
    Atractylon Treatment Attenuates Pulmonary Fibrosis via Regulation of the mmu_circ_0000981/miR-211-5p/TGFBR2 Axis in an Ovalbumin-Induced Asthma Mouse Model.

    Atractylon Treatment Attenuates Pulmonary Fibrosis via Regulation of the mmu_circ_0000981/miR-211-5p/TGFBR2 Axis in an Ovalbumin-Induced Asthma Mouse Model.
    Zeng H, Gao H, Zhang M, Wang J, Gu Y, Wang Y, Zhang H, Liu P, Zhang X, Zhao L.

    02/5/2022
    Skeletal Deformities in Osterix-Cre;Tgfbr2(f/f) Mice May Cause Postnatal Death.

    Skeletal Deformities in Osterix-Cre;Tgfbr2(f/f) Mice May Cause Postnatal Death.
    Corps K, Stanwick M, Rectenwald J, Kruggel A, Peters SB., Free PMC Article

    02/5/2022
    Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract.

    Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract.
    Ni N, Fang X, Li Q., Free PMC Article

    10/16/2021
    Tgfbeta signaling is critical for maintenance of the tendon cell fate.

    Tgfβ signaling is critical for maintenance of the tendon cell fate.
    Tan GK, Pryce BA, Stabio A, Brigande JV, Wang C, Xia Z, Tufa SF, Keene DR, Schweitzer R., Free PMC Article

    04/24/2021
    Mechanosensitive Control of Articular Cartilage and Subchondral Bone Homeostasis in Mice Requires Osteocytic Transforming Growth Factor beta Signaling.

    Mechanosensitive Control of Articular Cartilage and Subchondral Bone Homeostasis in Mice Requires Osteocytic Transforming Growth Factor β Signaling.
    Bailey KN, Nguyen J, Yee CS, Dole NS, Dang A, Alliston T., Free PMC Article

    03/28/2021
    miR-122-5p negatively regulates the transforming growth factor-beta/Smad signaling pathway in skeletal muscle myogenesis.

    miR-122-5p negatively regulates the transforming growth factor-β/Smad signaling pathway in skeletal muscle myogenesis.
    Ding Z, Lin J, Sun Y, Cong S, Liu S, Zhang Y, Chen Q, Chen J.

    02/2/2021
    Hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein (HIP/PAP) confers protection against hepatic fibrosis through downregulation of transforming growth factor beta receptor II.

    Hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein (HIP/PAP) confers protection against hepatic fibrosis through downregulation of transforming growth factor β receptor II.
    Li Q, Li H, Lv Y, Zhang Q, Zhang X, Li S, Zheng X, Wang Y, Hao Z.

    09/26/2020
    These findings highlight the relevance of TGFBR2-IL-36 interplay in joint homeostasis.

    TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
    Li T, Chubinskaya S, Esposito A, Jin X, Tagliafierro L, Loeser R, Hakimiyan AA, Longobardi L, Ozkan H, Spagnoli A., Free PMC Article

    07/18/2020
    TGFBRII-deficient mice manifest altered composition of gut microbiota; alteration of this gut microbiota by administration of antibiotics significantly alleviates T-cell-mediated infiltration and bile duct damage.

    Gut microbiota translocation promotes autoimmune cholangitis.
    Ma HD, Zhao ZB, Ma WT, Liu QZ, Gao CY, Li L, Wang J, Tsuneyama K, Liu B, Zhang W, Zhou Y, Gershwin ME, Lian ZX., Free PMC Article

    10/5/2019
    Deletion of phosphatase and tensin homolog (Pten) and transforming growth factor-beta receptor type 2 (Tgfbr2) may increase prostate epithelial cell reprogramming efficiency in vitro and cause rapid tumor development and early mortality in vivo.

    Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer.
    Zhao W, Zhu Q, Tan P, Ajibade A, Long T, Long W, Li Q, Liu P, Ning B, Wang HY, Wang RF., Free PMC Article

    09/14/2019
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